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Scientists discover how treating eczema could also alleviate asthma
Scientists from VIB-UGent have discovered insights for a possible new therapy for eczema that also reduces the severity of asthma. The findings are an important next step in understanding the relationship between the two inflammatory diseases and to developing effective therapies. The results of the study are published in the Journal of Investigative Dermatology.
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Research reveals atomic-level changes in ALS-linked protein
For the first time, researchers have described atom-by-atom changes in a family of proteins linked to amyotrophic lateral sclerosis (ALS), a group of brain disorders known as frontotemporal dementia and degenerative diseases of muscle and bone. Their findings appear in the journal "Molecular Cell".
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Zika virus damages placenta, which may explain malformed babies
Study finds abnormalities and decreased oxygen levels in placenta during fetal development.
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Efficacy of antibody targeting Devic's disease proven in new animal model
Osaka University study identifies antibody that alleviates symptoms in neuromyelitis optica in rats.
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First vaccine in the world developed against grass pollen allergy
Around 400 million people world-wide suffer in some form or other from a grass pollen allergy (rhinitis) – with the usual symptoms such as a runny nose, cough and severe breathing problems.
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DIPG tumor patterns offer new insight on survival
An analysis of several hundred DIPG and related tumors, including Chad Carr's, finds an overlooked key factor in determining prognosis for the aggressive childhood brain cancer.
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Breakthrough enables screening millions of human antibodies for new drug discovery
A paper just published in "Nature Biotechnology" outlines a pioneering method of screening a person's diverse set of antibodies for rapid therapeutic discovery. Antibody proteins are an important part of the human immune system that specifically target foreign viruses and bacteria, and they have been the fastest-growing class of approved drugs in the past several decades.
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Researchers identify new melatonin-based molecular targets for the design of new drugs against Parkinson's
A team of scientists led by Darío Acuña-Castroviejo, professor at the University of Granada (UGR), has published the results of a new breakthrough in molecular mechanisms of the anti-parkinsonian activity of melatonin.
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Genetic analysis can improve depression therapy
The failure of drugs such as SSRIs, used to treat depression, can be a result of genetic variations in patients. Variations within the gene that encodes the CYP2C19 enzyme results in extreme differences in the levels of escitalopram achieved in patients, according to a new study published in The American Journal of Psychiatry.
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