Novel transcriptomic signature of type 2 diabetic islets identified -- MEDICA - World Forum for Medicine

Novel transcriptomic signature of type 2 diabetic islets identified

12/13/2017

Image: green structure with pink spots on black background; Copyright: TU Dresden

Validation of PDX1 as transcription factors located upstream of the T2D islet signature genes. Co- immunostaining for insulin (green) and PDX1 (red) in human EndoC-βH1 cells. Nuclei are counterstained with DAPI (blue).