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Image: graphic of a DNA strand removed from the gold surface using the tip of an atomic force microscope; Copyright: University of Basel, Department of Physics

Cryo-force spectroscopy and computer simulations examine DNA

11/02/2019

Physicists from the University of Basel have developed a new method to examine the elasticity and binding properties of DNA molecules on a surface at extremely low temperatures. With a combination of cryo-force spectroscopy and computer simulations, they were able to show that DNA molecules behave like a chain of small coil springs.
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Image: robot hand from above on the keyboard; Copyright: panthermedia.net/ VitalikRadko

Using artificial intelligence for error correction

25/01/2019

Modern technology makes it possible to sequence individual cells and to identify which genes are currently being expressed in each cell. These methods are sensitive and consequently error prone.
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Image: black-white-photo of an old woman; Copyright: panthermedia.net/ photographee eu

Early Prediction of Alzheimer’s Progression in Blood

23/01/2019

Years before symptoms of Alzheimer’s disease manifest, the brain starts changing and neurons are slowly degraded.
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Image: blood vessel system in bones; Copyright: UDE/Matthias Gunzer, Annika Grüneboom

New blood vessel system discovered in bones

23/01/2019

A previously unknown network of fine capillaries directly connecting the bone marrow with the circulation of the periosteum has been discovered.
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Image: human lung; Copyright: panthermedia.net/net ilexx

Molecular profiling could catch lung cancer

22/01/2019

The world's first genetic sequencing of precancerous lung lesions could pave the way for very early detection and new treatments, reports a new study led by UCL researchers.
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Image: Schematic model of ChIL reaction; Copyright: Yuko Sato (Tokyo Institute of Technology)

When less is more: Approach for low-cell-number epigenomic profiling

14/12/2018

Scientists at Kyushu University and Tokyo Institute of Technology have developed a technique that enables analysis of DNA-protein interactions using very small numbers of cells, ranging from 100 to 1,000. Their method could capture previously unexamined epigenomic information, facilitate biomarker discovery and open new avenues for precision medicine.
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Image: Systic fibrosis treatment; Copyright: panthermedia.net / Ibrfzhjpf.gmail.com

Blood test could lead to cystic fibrosis treatment

14/12/2018

Researchers at Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago used a blood test and microarray technology to identify distinct molecular signatures in children with cystic fibrosis. These patterns of gene expression could help predict disease severity and treatment response, and lead to therapies tailored to each patient's precise biology.
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Image: The MPI team: Noelia Díaz, Kai Kruse and Juanma Vaquerizas; Copyright: MPI Münster

Nuclear architecture diagnostics within reach of the clinic

07/12/2018

Scientists at the Max Planck Institute of Molecular Biomedicine in Münster and of the Medical Faculty of the University of Münster have developed a technique that allows the characterisation of the three-dimensional organisation of the DNA in the nucleus directly in patient's cells.
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Image: Doctor on a computer display examines RNA-sequences; Copyright: panthermedia.net / Lev Dolgachov

New technique improves single cell RNA sequencing

26/11/2018

In the era of personalized medicine, scientists are using new genetic and genomic insights to help them determine the best treatment for a given patient. In the case of cancer, the first step toward these treatments is an investigation into how tumor cells behave in an effort to figure out the best drugs to use to attack them.
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Image: A group of physicians is holding large colorful puzzle pieces in their hands and is putting them together; Copyright: panthermedia.net/Andriy Popov

Personalized medicine: a paradigm shift is gaining momentum

01/03/2018

Personalized medicine does not follow a "one-size-fits-all" treatment approach but emphasizes a "tailor-made" paradigm, meaning a treatment is customized to each individual person's case. For patients, this increases the chances of treatment success and means fewer side effects. While the approach originates in the field of oncology, it is now also increasingly applied to other disease patterns.
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Image: Three men in suits and a woman in a laboratory coat are standing in a laboratory; Copyright: Ministry of Economy of Mecklenburg-Hither Pomerania/Norbert Fellechner

On the trail of cancer: personalized cancer vaccine

01/03/2018

Conventional cancer treatment selection typically depends on the location of the tumor. However, this approach ignores the distinct gene mutations in the tumor of the individual patient. New cancer research approaches increasingly emphasize the concept of personalized therapy.
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Image: Different medical pictograms; Copyright: panthermedia.net/aimage

Collect Data? Utilize Data! – The Blessings of Big Data

01/03/2017

Genome data, MRI images, and blood test results – data collected in the medical sector is not only very heterogeneous but also extremely extensive. However, it is important to not only collect this data but to also utilize it. After all, processed, linked and analyzed data provides many opportunities in research, hospital management and ultimately also for the individual patient.
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Image: Look over the shoulder of an eye surgeon who is operating at a microscope; Copyright: panthermedia.net/mearicon

Ophthalmology today and tomorrow: surgery and more

01/02/2017

Ophthalmology procedures and eye surgeries have been around since ancient times. Today we can hardly imagine the types of circumstances that surrounded any surgical procedures to our perhaps most important sense organ in those days and later eras. Meanwhile, the present and future of this medical specialty looks all the more promising.
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Image: Image of a bird in greyscale and blurred; Copyright: Universitätsklinikum Tübingen

Gene therapy for the treatment of achromatopsia

01/02/2017

Achromatopsia is a rare hereditary visual disorder. Along with total color blindness, patients most notably suffer from reduced visual acuity and increased sensitivity to light and glare.
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