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Image: graphic of a DNA strand removed from the gold surface using the tip of an atomic force microscope; Copyright: University of Basel, Department of Physics

Cryo-force spectroscopy and computer simulations examine DNA

11/02/2019

Physicists from the University of Basel have developed a new method to examine the elasticity and binding properties of DNA molecules on a surface at extremely low temperatures. With a combination of cryo-force spectroscopy and computer simulations, they were able to show that DNA molecules behave like a chain of small coil springs.
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Image: Schematical drawing to explain a blood test; Copyright: NHLBI

Can a blood test detect lung-transplant rejection?

29/01/2019

Researchers have developed a simple blood test that can detect when a newly transplanted lung is being rejected by a patient, even when no outward signs of the rejection are evident.
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Image: robot hand from above on the keyboard; Copyright: panthermedia.net/ VitalikRadko

Using artificial intelligence for error correction

25/01/2019

Modern technology makes it possible to sequence individual cells and to identify which genes are currently being expressed in each cell. These methods are sensitive and consequently error prone.
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Image: Three men in suits and a woman in a laboratory coat are standing in a laboratory; Copyright: Ministry of Economy of Mecklenburg-Hither Pomerania/Norbert Fellechner

On the trail of cancer: personalized cancer vaccine

01/03/2018

Conventional cancer treatment selection typically depends on the location of the tumor. However, this approach ignores the distinct gene mutations in the tumor of the individual patient. New cancer research approaches increasingly emphasize the concept of personalized therapy.
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Image: A group of physicians is holding large colorful puzzle pieces in their hands and is putting them together; Copyright: panthermedia.net/Andriy Popov

Personalized medicine: a paradigm shift is gaining momentum

01/03/2018

Personalized medicine does not follow a "one-size-fits-all" treatment approach but emphasizes a "tailor-made" paradigm, meaning a treatment is customized to each individual person's case. For patients, this increases the chances of treatment success and means fewer side effects. While the approach originates in the field of oncology, it is now also increasingly applied to other disease patterns.
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Image: yellow tape measure with capsules in front of it; Copyright: panthermedia.net/Jiri Hera

Personalized cancer medicine: customized treatment

01/03/2018

Everyone is different. This statement also applies to our health. Cancer, in particular, can look and progress differently depending on the individual person. That’s why every patient ideally also needs a customized treatment that is tailored to their individual needs. But how feasible is this idea?
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Image: Collage made of two images, one show a round, transparent plastic disc with micro channels, one shows a plastic chip; Copyright: Hahn-Schickard, Image Bernd Müller

Prenatal diagnosis: genetic analysis using droplet PCR

24/07/2017

A new analysis method that uses fetal DNA extracted from the mother’s blood is designed to non-invasively reach a prenatal diagnosis of genetic disorders in a child. A task force of the Hahn Schickard Society for Applied Research is an active part of the "ANGELab" project and co-developed this diagnostic procedure.
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Image: Children playing outside, getting wet in the water; Copyright: panthermedia.net/Wavebreakmedia ltd

Pneumonia in Children: Ultrasound or X-Rays?

08/03/2017

Pneumonia is the most frequent respiratory disease in children and can even cause death. That is why it is extremely important to make an accurate diagnosis as quickly as possible. If this requires imaging tests, normally X-rays are taken. But there is an alternative: ultrasound.
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Image: Different medical pictograms; Copyright: panthermedia.net/aimage

Collect Data? Utilize Data! – The Blessings of Big Data

01/03/2017

Genome data, MRI images, and blood test results – data collected in the medical sector is not only very heterogeneous but also extremely extensive. However, it is important to not only collect this data but to also utilize it. After all, processed, linked and analyzed data provides many opportunities in research, hospital management and ultimately also for the individual patient.
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Image: Image of a bird in greyscale and blurred; Copyright: Universitätsklinikum Tübingen

Gene therapy for the treatment of achromatopsia

01/02/2017

Achromatopsia is a rare hereditary visual disorder. Along with total color blindness, patients most notably suffer from reduced visual acuity and increased sensitivity to light and glare.
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