03/01/2019A technique that enables biologically active enzymes to survive the rigors of inkjet printing presents a promising alternative to routine blood screening exams faced by diabetic patients. The KAUST-led team used this approach to make disposable devices that can measure glucose concentrations in human saliva.
02/01/2019For a study published in Genome Biology, a team at the Salk Institute analyzed skin cells ranging from the very young to the very old and looked for molecular signatures that can be predictive of age. Developing a better understanding of the biological processes of aging could eventually help to address health conditions that are more common in old age, such as heart disease and dementia.
02/01/2019The spread of invasive cancer cells from a tumor's original site to distant parts of the body is known as metastasis. It is the leading cause of death in people with cancer. In a paper published online in iScience, University of California San Diego School of Medicine researchers reported engineering sensors that can detect and measure the metastatic potential of single cancer cells.
06/12/2018In the diagnosis of Alzheimer's disease and the search for effective treatments, tau tangles in the brain have joined amyloid build-up as markers of the disease and potential therapy targets. In the December issue of The Journal of Nuclear Medicine, the featured article of the month reports on the identification of a promising second-generation positron emission tomography (PET) tracer.
05/11/2018A chemical that highlights tumour cells has been used by surgeons to help spot and safely remove brain cancer in a trial presented at the 2018 NCRI Cancer Conference.
01/11/2018A team led by a Cedars-Sinai physician-scientist has discovered a biomarker - a protein found in the blood - for the most common type of heart failure.
30/10/2018Autism spectrum disorder (ASD) is a neurodevelopmental disorder that can impair communication ability, socialization, and verbal and motor skills. It generally starts in early childhood and is diagnosed through behavior observation. This means of assessment can be imprecise, which is especially problematic when early identification is vital for developmental follow up.
09/07/2018People who are not ill and do not show any symptoms typically do not visit the doctor. And while most people know that preventive medical checkups for cancer, for example, are important, they still avoid them. They tend to be very hesitant because the doctor might detect a serious illness. In the future, a new type of implant could make it easier to go to a screening test.
01/03/2018Personalized medicine does not follow a "one-size-fits-all" treatment approach but emphasizes a "tailor-made" paradigm, meaning a treatment is customized to each individual person's case. For patients, this increases the chances of treatment success and means fewer side effects. While the approach originates in the field of oncology, it is now also increasingly applied to other disease patterns.
08/11/2017Major surgeries in the abdominal region often result in kidney injury in patients. Meanwhile, the clinical manifestations don't present until one or two days after the procedure. This causes physicians to lose valuable time to treat patients. The University Hospital Regensburg has researched a new concept for the treatment of kidney injuries for several years.
24/07/2017A new analysis method that uses fetal DNA extracted from the mother’s blood is designed to non-invasively reach a prenatal diagnosis of genetic disorders in a child. A task force of the Hahn Schickard Society for Applied Research is an active part of the "ANGELab" project and co-developed this diagnostic procedure.
03/04/2017The laboratory is one of the most important and pivotal bastions in patient care. In the laboratory, acute, chronic and genetic diseases are diagnosed, the progression of diseases such as diabetes is regularly checked or specialists look for biomarkers to adapt cancer therapies.
08/04/2016A diagnosis of diabetes often catches new patients off guard - for instance if they end up in the emergency room suffering from metabolic decompensation. Children are often affected by this. Their immune system destroys the insulin-producing cells in the pancreas early on in their lives, thus causing type 1 diabetes.
22/03/2016Medical apps like diabetes or high blood pressure diaries are becoming increasingly popular with smartphone users. There are many available choices out there but they are not always clear. Added to this is the question of how the data collected by the apps can be sensibly incorporated into treatment.
08/03/2016Pancreatic cancer is one of the deadliest forms of cancer because it is difficult to diagnose and only presents with symptoms in the later stages. In the future, a laboratory test developed at the Greifswald University Medicine could make an early detection of this type of cancer and consequently a faster and better treatment possible.
01/10/2015It is a portmanteau, a mixture of two words. This way it saves us time and trouble while speaking because the human speech apparatus is lazy. And it describes a mixture of procedures: the combination of two procedures that would normally be separate in medicine. We are talking about theranostics.
01/09/2015They can be seen everywhere: at the wrists, in the ear, clipped to the belt. Wearables are small technical assistants who are built to collect and partially also to analyze data. Some of them collect measurable health data, others "only" count their user’s steps or measure the surrounding UV radiation. The fact is, however, that wearables are en vogue and are used for many different cases.
03/08/2015Endoradiotherapy can be very unpleasant for cancer patients, since it does not only harm tumor cells, but also healthy ones. Sometimes, patients even need to stop therapy because of the side effects. Physicians and researchers are thus continuously searching for ways to transport radiopharmaceuticals directly and exclusively to their target.
01/06/2015Can liquid biopsies become the new trend in cancer diagnostics? The medical world has asked this question for quite some time. The first globally approved liquid biopsy-based test for lung cancer shows that this can work. Yet further findings and research are still required to establish this less invasive method in diagnostics.
01/06/2015A tumor is as unique as the person who is affected by it. For a long time, it was assumed this would make treatment more difficult since cancer drugs are not able to be one hundred percent effective in targeting the affected cells. In this interview with MEDICA.de, Professor Ugur Sahin explains why it is precisely these individual mutations that make him hopeful for a new type of therapy.
01/06/2015When cancer is diagnosed, the terms tumor markers or biomarkers keep popping up. They describe characteristics that are not found in healthy persons. The classic tumor markers can be easily detected in blood samples or other body fluids. Other analysis methods require more effort. Yet they all share one thing in common: biomarkers indicate a potential tumor.
02/02/2015Only projects with a solid foundation are successful in the long run. This is also true for science. Biobanks are the most important component of this foundation when it comes to fundamental biomedical research: Only high quality tissue samples that are stored there make conclusive research possible - for example in search of the causes of tumorigenesis.