03/04/2019From birth through to death, cells lead an eventful existence. Thanks to single-cell genomics, their destiny can be analyzed. But this method destroys the cell. In order to address this problem, researchers at the Helmholtz Zentrum München and the University of Massachusetts use pseudodynamics, a mathematical model that estimates developmental processes from single-cell time series observations.
25/03/2019Researchers tracked and quantified the production of different kinds of blood cells and immune cells to understand how the body maintains a balanced supply.
07/03/2019Scientists from Utrecht University, University Medical Center Utrecht and Hubrecht Institute have successfully created kidney organoids from urine cells. This could lead to a wide range of new treatments that are less onerous for kidney patients.
01/02/2019Organ-on-a-chip systems are technically a great enhancement of medical research because they facilitate testing of active ingredients on cell cultures in the chambers of a plastic chip. This replaces animal testing and improves patient safety. That being said, they are not a true-to-life replication of the human body and can only simulate a few functions and activities.
31/01/2019Scientists have successfully constructed a three-dimensional human epidermis based on predictions made by their mathematical model of epidermal homeostasis, providing a new tool for basic research and drug development.