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Image: A physician's hands on a laptop with a stethoscope next to it; Copyright: panthermedia.net/Rangizzz

eHealth: antibiotic overprescribing thanks to telemedicine

08/04/2019

Children with acute respiratory infections were prescribed antibiotics more often during direct-to-consumer telemedicine visits than during in-person primary care appointments or urgent care visits, according to UPMC Children's Hospital of Pittsburgh research reported today in Pediatrics.
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Image: close-up of a crying young woman; Copyright: panthermedia.net/IgorTishenko

Data science: treatments for depression

14/03/2019

Major depressive disorder is a debilitating illness that affects more than 350 million people around the world. The most common treatments for depression are Selective Serotonin Reuptake Inhibitors (SSRIs), drugs such as Prozac that increase serotonin levels in some regions of the brain. About half of the patients who take the pills, however, do not respond to treatment.
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Image: graphic showing how Usiigaci works; Copyright: OIST

Machine learning tracks moving cells

14/03/2019

Both developing babies and elderly adults share a common characteristic: the many cells making up their bodies are always on the move. As we humans commute to work, cells migrate through the body to get their jobs done. Biologists have long struggled to quantify the movement and changing morphology of cells through time, but now, scientists have devised an elegant tool to do just that.
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Image: senior coughing man with cigarette; Copyright: panthermedia.net/ljsphotography

All-round care for COPD: diagnosis, treatment, self-management

01/03/2019

COPD affects more than 200 million people in the world. Those affected by this chronic pulmonary disease are often slow to notice the symptoms and get a medical diagnosis. This results in secondary complications and high medical costs. That's why an early diagnosis, comprehensive treatment, and frequent monitoring are very important. Various devices and tools support this all-round care.
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Image: Dosage inhaler and stethoscope in front of a shelf; Copyright: panthermedia.net/liudmilachernetska@gmail.com

React early, breathe free – comprehensive COPD management

01/03/2019

COPD is considered the third most common cause of death worldwide and mainly affects smokers. It is not curable, but with the right combination of early diagnosis, therapy and self-management, a significant part of the quality of life can be regained. The comprehensive care is supported by various devices and technical tools. Learn more about the all-round care of COPD in our Topic of the Month.
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Image: An old man using an asthma inhaler; Copyright: panthermedia.net/ljsphotography

New big data method helps asthma patients

28/02/2019

Physicians will be able to predict which of their patients with severe asthma are likely to benefit from treatment with systemic corticosteroids - and which might only suffer their side effects - with help from a dozen clinical variables researchers have identified using machine learning techniques.
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Image: A man and a woman working in a laboratory; Copyright: Jan-Peter Kasper/University Jena

Test system helps preventing chronic inflammation

25/02/2019

An international research team led by Friedrich Schiller University in Jena has developed a highly sensitive cell model to study the complex effects – and side effects – of anti-inflammatory drugs, with the ultimate aim of preventing chronic inflammation.
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Image: Preemie doll with drug delivery system on the nose; Copyright: Fraunhofer ITEM/Till Holland

Gentle medication for the little ones – with every breath

22/02/2019

According to the WHO, ten percent of babies worldwide are born prematurely. Since most organs of these tiny babies have not fully developed yet, it can quickly lead to complications and disorders and most notably affect the lungs of the premature infants. What's more, infections require gentle treatment, as the preemies themselves are fragile and susceptible – making this a challenging situation.
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Image: two men in the laboratory talking about a document in their hands; Copyright: panthermedia.net/Phovoi R.

Machine learning algorithm helps in the search for new drugs

12/02/2019

Researchers have designed a machine learning algorithm for drug discovery which has been shown to be twice as efficient as the industry standard, which could accelerate the process of developing new treatments for disease.
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Image: 3D bioprinting the Tumor Micro Environment of a glioblastoma; Copyright: University of Twente

3D-bioprinted brain tumor shows interaction with immune cells

11/02/2019

Around a glioblastoma, a very aggressive brain tumor, cells of the human immune system start helping the tumor instead of attacking it. To do research on what happens in the interaction of these cells, scientists of the University of Twente now created a 3D-bioprinted mini model of the brain.
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Image: brain with syringe and medication; Copyright: panthermedia.net / Michael Osterrieder

Breakthrough for brain tumor drug development

07/02/2019

24,000 patients are diagnosed with brain tumors every year with the 5yr survival for high grade glioblastomas (GBM) only 5%, with median survival of 15 months. These poor statistics have remained static for 30 years due in part to a lack of preclinical models for testing new drugs.
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Image: Artificial intelligence-tool; Copyright: Nature/Nigam Shah, Adrien Coulet

Artificial intelligence-tool for chemotherapy dosages

05/02/2019

Finding the right dose of medication by trial and error can be a painful experience for patients. Thanks to a new algorithm created by Adrien Coulet, lecturer at the Université de Lorraine and researcher in a joint Inria and Loria team, in collaboration with researchers from Stanford University, an innovative tool can predict in advance whether patients will need a lower dose of medication.
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Image: A female researcher is looking at a sample on a glass slide; Copyright: Tristan McGuirk

How to train lab-grown heart cells

01/02/2019

Heart muscle cells need exercise - even when they grow outside the human body. A new device designed by U of T Engineering researchers uses a rigorous training regimen to grow small amounts of cardiac tissue and measure how strongly it beats. The platform is ideal for testing the effects of potential drug molecules and could help bring personalized medicine closer to reality.
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Hybrid Imaging – Two Views of the Lungs

25/01/2019

CT scan, MRI or X-ray: All these methods allow doctors to see inside the body - including inside the lungs - and make a diagnosis. The clinic for Nuclear Medicine at the RWTH Aachen University Hospital uses a state-of-the-art gamma camera that combines SPECT and CT.
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The cure is in the capsule: carbon monoxide to treat chronic inflammation

22/05/2018

This unusual ally can be extremely valuable in the fight against inflammation in the body: CO (carbon monoxide). As a therapeutic gas, it also promises relief for inflammatory gastrointestinal diseases. Having said that, it is difficult to transport the active ingredient to the exact desired location.
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Image: a container with the nutrient medium for cancer cells; Copyright: Dr. Markus Wehland

Cells in space – extraterrestrial approaches in cancer research

22/02/2018

Here on Earth, all experiments are bound by gravitation. Yet, freed from gravity's grip, tumor cells, for example, behave in an entirely different way. As part of the "Thyroid Cancer Cells in Space" project by the University of Magdeburg, smartphone-sized containers carrying poorly differentiated thyroid cancer cells are sent into space.
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Image: blood is taken from a finger and analysed by a blood testing device; Copyright:hes_so_valais_wallis

Without any delay: drug dose adjustment at the point of care

01/08/2017

Many therapeutic drugs are very powerful, but they are also very toxic at the same time. Thus, they have to be measured regularly, again and again, so that an adjustment of the individual drug dosage can be made. Until now, the "normal" way was to take the blood sample, send it to a central laboratory and get the results after some days. A new point-of-care test can measure it in 15 minutes.
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Swallowing Disorders – avoiding errors related to medication administration

27/01/2017

Dysphagia creates a stressful situation for patients. Added to this is the fact that acute errors in the treatment of swallowing disorders keep occurring when patients are administered drugs. How can patients with swallowing difficulties receive better care? We visited the Hüttenhospital Dortmund and asked Dr. Martin Jäger, an expert in this particular field.
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