01/02/2019Heart muscle cells need exercise - even when they grow outside the human body. A new device designed by U of T Engineering researchers uses a rigorous training regimen to grow small amounts of cardiac tissue and measure how strongly it beats. The platform is ideal for testing the effects of potential drug molecules and could help bring personalized medicine closer to reality.
23/07/2018Every year, more than 250,000 patients worldwide receive heart valve implants. Children require repeated replacement surgery because their bodies are still growing, the prosthetic heart valves are not. Regenerative heart valves solve this problem. Until now, we have only been able to monitor how these living implants develop in the body after the fact. Computer models now make this predictable.
23/04/2018A bypass is a complicated structure. It is either made of synthetic materials that can cause blood clots and infections or created by using the patient’s veins. However, the latter often does not yield adequate material. A newly developed bioreactor could solve this problem in the future. It is designed to tissue engineer vascular grafts by using the body’s own material.