05/04/2019Researchers have developed a computational model for human MEK1, a protein with potential as a drug target for a variety of human cancers.
01/04/2019A research team led by biophysical chemist Professor Edward Lemke has engineered a designer organelle in a living mammalian cell in a new complex biological translation process. The created membraneless organelle can build proteins from natural and synthetic amino acids carrying new functionalities.
01/04/2019High-resolution optical microscopy methods promise breakthroughs in materials science, biology, and medicine. Today, their possibilities basically reach those of scanning electron microscopy.
18/03/2019A new method to diagnose cancer cells inside lymph nodes could allow doctors to treat cancers before they spread around the body
19/02/2019Researchers from Chalmers University of Technology, Sweden, have devised a new method to study how single biological cells react to stressful situations. Understanding these responses could help develop more effective drugs for serious diseases.
08/02/2019Human tissues experience a variety of mechanical stimuli that can affect their ability to carry out their physiological functions, such as protecting organs from injury. The controlled application of such stimuli to living tissues in vivo and in vitro has now proven instrumental to studying the conditions that lead to disease.
07/02/2019X-rays provide unique insights into the interior of materials, tissues, and cells. Researchers at the Paul Scherrer Institute PSI have developed a new method that makes X-ray images even better: The resolution is higher and allows more precise inferences about the properties of materials.
07/02/201924,000 patients are diagnosed with brain tumors every year with the 5yr survival for high grade glioblastomas (GBM) only 5%, with median survival of 15 months. These poor statistics have remained static for 30 years due in part to a lack of preclinical models for testing new drugs.
06/02/2019Excess weight and obesity are two global health issues. According to data of the World Health Organisation (WHO), over 50% of the European population is overweight and 20% is obese. In Spain, the situation is similar: in the last 30 years, obesity among adults has increased. More than half the adult population (54.5%) is overweight.
01/02/2019In vitro processes and animal tests are used to develop new medications and novel therapeutic approaches. However, animal testing raises important ethical concerns. Organ-on-a-chip models promise to be a feasible alternative. In a system the size of a smartphone, organs are connected using artificial circulation.
01/02/2019The liver, nervous tissue or the intestines: all are important human organs that have in the past been tested for their function and compatibility using animal or in vitro test methods. In recent years, TissUse GmbH, a spin-off of the Technical University of Berlin (TU Berlin), has launched multi-organ chip platforms. But that’s not all.
08/01/2019Parkinson's disease is a progressive nervous system disorder that primarily affects movement of patients and makes their everyday lives very challenging. It also makes regular doctor appointments and treatment sessions necessary. "TelePark" - a project that collects different movement-related parameters using sensors and apps is designed to improve the quality of life for Parkinson’s patients.
02/01/2019Diabetes mellitus or simply diabetes has become very common and is often described as a lifestyle disease. More and more people are suffering from this chronic metabolic disorder. Next to established diagnostic procedures, digital retinal screening has shown to be successful - a promising technique that will also play an important role in the diagnosis of other diseases in the future.
01/02/2018Hospitals need an accurate assessment of the location and quantity of their materials to eliminate sources of error. Automated processes can also help employees to make these materials available at the right time and at the right place. Digital network systems will substantially support the logistics in the hospital of the future.
22/05/2017For many years, cochlear implants have restored a sense of hearing in people with certain types of hearing loss. For surgeons, the implantation requires a precise attention to detail under the microscope. The results for the patients improve significantly with a more precise placement of the electrode array. The use of a surgical robot can increase the accuracy of the procedure.
22/02/2017Surgeons need a great sense of touch. They first have to acquire this skill in simulation training before they can perform surgery on actual patients. Having said that, simulators are not just meant to teach the right movements; ideally, they should also provide a true-to-life experience of the surgical field – as is the case in RealSpine surgical training.