Miele OxiVario Plus reprocessing method: 'In vivo' proof of prion decontamination
Miele's OxiVario Plus instrument reprocessing method, which ensures particularly high levels of cleaning performance in washer-disinfectors, has recently been investigated with respect to its ability to decontaminate surface-adherent prions, the pathogens behind the Creutzfeld-Jacob disease. These results have since been confirmed by further 'in vivo' experiments performed by the Institute of Neuropathology at the University of Munich. This paves the way for a declaration of efficacy according to the criteria laid down by Germany's Robert Koch Institute, which requires that 'in vivo' tests be performed.
The current series of tests involved involved implanting tiny metal plates previously contaminated with tissue containing prions in mice. Only the mice implanted with material previously decontaminated in the OxiVario Plus process or sterilised in steam for two hours at 134°C showed no signs of contracting the disease. On the other hand, mice implanted with metal plates reprocessed using the standard Vario TD process or with an 100 million fold prion solution dilution contracted the disease and died. Work is already underway to publish the test results.