Max Planck Innovation GmbH, the technology transfer agency of the Max Planck Society, Germany’s leading basic research organization, has signed a co-exclusive license agreement with GHE-member Leica Microsystems and Carl Zeiss MicroImaging GmbH for the RESOLFT (reversible saturable optical fluorescent transitions) technology, a method providing molecular scale resolution with visible light and regular lenses for use in microscopy.
The technology is breaking the century-old diffraction resolution barrier in conventional microscopy and allows for resolution of the size order of a dye molecule, i.e. a sharpness of one or two nanometers. While a number of technologies such as electron microscopy exist to visualize virus particles, sub cellular structures and macromolecules, RESOLFT fluorescence microscopy for the first time enables researchers to observe these structures inside of living cells without destroying them.
Both licensees will now seek to develop novel microscopes and imaging technologies based on the RESOLFT technology.