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Efficacy of antibody targeting Devic's disease proven in new animal model
Osaka University study identifies antibody that alleviates symptoms in neuromyelitis optica in rats.
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First vaccine in the world developed against grass pollen allergy
Around 400 million people world-wide suffer in some form or other from a grass pollen allergy (rhinitis) – with the usual symptoms such as a runny nose, cough and severe breathing problems.
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DIPG tumor patterns offer new insight on survival
An analysis of several hundred DIPG and related tumors, including Chad Carr's, finds an overlooked key factor in determining prognosis for the aggressive childhood brain cancer.
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Breakthrough enables screening millions of human antibodies for new drug discovery
A paper just published in "Nature Biotechnology" outlines a pioneering method of screening a person's diverse set of antibodies for rapid therapeutic discovery. Antibody proteins are an important part of the human immune system that specifically target foreign viruses and bacteria, and they have been the fastest-growing class of approved drugs in the past several decades.
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Researchers identify new melatonin-based molecular targets for the design of new drugs against Parkinson's
A team of scientists led by Darío Acuña-Castroviejo, professor at the University of Granada (UGR), has published the results of a new breakthrough in molecular mechanisms of the anti-parkinsonian activity of melatonin.
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Genetic analysis can improve depression therapy
The failure of drugs such as SSRIs, used to treat depression, can be a result of genetic variations in patients. Variations within the gene that encodes the CYP2C19 enzyme results in extreme differences in the levels of escitalopram achieved in patients, according to a new study published in The American Journal of Psychiatry.
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Anorexia aggravates disease progression in heart failure
Researchers of the German Centre for Cardiovascular Research (DZHK) have discovered that patients with heart failure who have anorexia are also more affected in their physical functional capacity and have worse prognosis. Factors that encourage anorexia are the intake of diuretic medication, inflammation, and involuntary weight-loss.
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Successful simulation of a real-time migraine prediction system
UPM researchers, in collaboration with UCM and Hospital Universitario de la Princesa, have successfully simulated a system that alert patients to an incoming migraine crisis in real time. According to the simulation results, the reliability of this system is over 75 percent.
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Researcher publishes groundbreaking plan to end bowel cancer
A groundbreaking report, led by Professor Mark Lawler, Chair in Translational Cancer Genomics at Queen’s University Belfast highlights a plan to end bowel cancer, the second most common cause of cancer death in Europe.
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New therapeutic approach for advanced lung disease
COPD patients suffer from chronic inflammation of the respiratory tract. Certain enzymes, so-called protein kinases, regulate the inflammation process. They are indirectly over-activated due to smoking, due to pro-inflammatory factors characteristic of COPD, and due to respiratory infections.
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