Exploit Technologies Pte Ltd.

COrneaL GrAft Thickness Evaluation based on Optical Coherence Tomography Image (COLGATE)

The cornea is the window of the eye and when it is severely damaged or diseased, vision is impaired.Descemet’s Stripping Automated Endothelial Keratoplasty(DSAEK) is a surgical procedure to replace the malfunctioned Descemet’s membrane with a healthy one in order to restore the patient’s sight. After the operation, ophthalmologists need to monitor the grafted membrane to check for signs of detachment, rejection, etc. and take appropriate actions before graft failure occurs.

The COLGATE System is a semi-automated system we developed to facilitate the evaluation of the corneal graft based on OCT images. It aims to assist ophthalmologists to examine the transplanted graft in Descemet’s Stripping Automated Endothelial Keratoplasty (DSAEK),which is an advanced procedure to replace the diseased Descemet’s membrane. The measurement accuracy is roughly 88.4% at the graft central region and 92.4% at the graft edge region.

The Technology can be implemented in currently available instruments without extensive modifications. The Technology could potentially be of interest to ocular instrument makers to incorporate the Technology into their equipment, and to health institutions such as clinics and hospitals for diagnosis.