The CF StripAssay (4-410) will cover 34 mutations and one polymorphism (IVS8 5T/7T/9T) in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene. It includes all 23 CFTR mutations that have been recommended by the American College of Medical Genetics (ACMG) to be essential for comprehensive cystic fibrosis (CF) testing. It will therefore be of general and widespread utility in many different areas and populations.
First in a series of population-specific CF StripAssays, we are also releasing a test covering the 24 most common CFTR mutations in the Turkish population (CF Stripassay TUR; 4-420).
Both assays are based on the use of two separate teststrips per patient (i.e. 10 tests per kit).