Blood vessel-on-a-chips show anti-cancer drug effects in human cells -- MEDICA Trade Fair

Blood vessel-on-a-chips show anti-cancer drug effects in human cells

02/09/2018

Image: VEGF stimulates the formation of sprouts on the vessel; Copyright: 2018 Yukiko Matsunaga, Institute of Industrial Science, the University of Tokyo

"The biochemistry of sprouting angiogenesis is well understood. VEGF leads endothelial cells to express DLL4, which activates NOTCH signaling. What is lacking is a good system to study drugs that are effective on angiogenesis," said Matsunaga.