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Image: illustration of equal and unequal crossovers during meiosis; Copyright: University of Rochester illustration / Michael Osadciw

Gene controlling genetic recombination rates

25/04/2018

Genetics is a crapshoot. During sexual reproduction, genes from both the mother and the father mix and mingle to produce a genetic combination unique to each offspring. In most cases, the chromosomes line up properly and crossover. In some unlucky cases, "selfish DNA" enters the mix, causing abnormal crossovers with deletions or insertions in chromosomes, which can manifest as birth defects.
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Image: fish counter; Copyright: Chalmers University of Technology

Eating more fish could prevent Parkinson's disease

25/04/2018

A new study from Chalmers University of Technology, Sweden, shines more light on the link between consumption of fish and better long-term neurological health. Parvalbumin, a protein found in great quantities in several different fish species, has been shown to help prevent the formation of certain protein structures closely associated with Parkinson's disease.
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Image: woman who cleans her nose among flowers; Copyright: Fotolia

Our genes dictate who develops an allergy

24/04/2018

Whether or not you develop an allergy is largely dependent upon genetic factors. This is the main finding of a study recently published in EBioMedicine, just in time for World Allergy Week (22-28. April 2018). The study was supervision of Winfried F. Pickl from MedUni Vienna's Institute of Immunology.
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Image: bright colours that flow into each other: illustration of EMT; Copyright: Université libre de Bruxelles

Cancer: Tumor transition states

24/04/2018

Tumor heterogeneity describes the differences between different cells within a given tumor. These differences have major implications for the diagnosis, prognosis, and therapy of cancer patients. Different mechanisms have been proposed to account for tumor heterogeneity such as epithelial to mesenchymal transition (EMT).
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Image: toddler who gets vaccined in the arms of a nurse; Copyright: panthermedia.net/evgenyataman

European Immunization Week 2018 – the right to be protected or the duty to protect?

23/04/2018

The European Immunization Week's general slogan "Prevent. Protect. Immunize" is more relevant than ever in times of globalization and migration. It is a political and structural challenge to give as many people as possible access to vaccination. But even the best care is of no use if the individual does not recognize his or her duty to society.
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Image: two men in the laboratory, one sitting at a microscope or similar, another standing behind him; Copyright: RUB, Kramer

Cancer drug observed at work

23/04/2018

Using a Raman microscope, researchers at Ruhr-Universität Bochum have studied at which targets the cancer drug Neratinib binds in cells and how its chemical structure changes. Compared with other techniques, this method offers a considerable advantage, as it is not necessary to apply a label to the drug that would indicate its distribution indirectly; rather, the drug itself can be monitored.
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Image: Mouse cells with (left) or without (right) DOR protein in green and blue ob black ground; Copyright: M. Romero, IRB Barcelona

DOR protein deficiency favours the development of obesity

23/04/2018

Obesity is a world health problem since excessive accumulation of fat tissue (or adipose tissue) increases the risk of cardiovascular disease, hypertension, diabetes and some types of cancer. However, some obese individuals are less susceptible to these conditions.
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Image: Abnormally activated astrocytes were accumulated in the lesion of ALS mouse without TRIF signaling; Copyright: Koji Yamanaka

Innate immune adaptor TRIF confers neuroprotection in ALS mice by eliminating abnormal glial cells

20/04/2018

Researchers led by Nagoya University revealed that deficiency of the innate immune adaptor TRIF significantly shortened survival time of ALS mice.
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Image: photo of photosensitizer conjugate; Copyright: Lobachevsky University

New highly selective antitumor photodynamic therapy agents synthesized

20/04/2018

This project is a result of collaboration of the Organic Chemistry Department and the Biophysics Department at the Lobachevsky University with the Research Institute of Macroheterocyclic Compounds.
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Image: scientist in the laboratory - Dr. Ryan A. Davis; Copyright: Phil Jones, Senior Photographer, Augusta University

Antioxidant therapy may reduce cardiovascular risk of young women with type 1 diabetes

19/04/2018

The high estrogen levels that typically afford younger women protection from cardiovascular disease appear to instead multiply their risk if they have type 1 diabetes, researchers say.
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