13/02/2019Stimulating the brain with implanted electrodes is a successful, but very drastic measure. Researchers from Eindhoven University of Technology, Kempenhaeghe, Philips and Gent University will therefore be working on a method to stimulate the brain using electrodes that are placed on the head rather than inside it. Their goal is to customize treatment for patients with severe epilepsy.
08/02/2019Researchers at Rensselaer Polytechnic Institute who developed a blood test to help diagnose autism spectrum disorder have now successfully applied their distinctive big data-based approach to evaluating possible treatments.
07/02/201924,000 patients are diagnosed with brain tumors every year with the 5yr survival for high grade glioblastomas (GBM) only 5%, with median survival of 15 months. These poor statistics have remained static for 30 years due in part to a lack of preclinical models for testing new drugs.
06/02/2019Excess weight and obesity are two global health issues. According to data of the World Health Organisation (WHO), over 50% of the European population is overweight and 20% is obese. In Spain, the situation is similar: in the last 30 years, obesity among adults has increased. More than half the adult population (54.5%) is overweight.
05/02/2019Finding the right dose of medication by trial and error can be a painful experience for patients. Thanks to a new algorithm created by Adrien Coulet, lecturer at the Université de Lorraine and researcher in a joint Inria and Loria team, in collaboration with researchers from Stanford University, an innovative tool can predict in advance whether patients will need a lower dose of medication.
05/02/2019A new technique to study tissue samples in 3D has revealed that pancreatic cancers can start and grow in two distinct ways, solving a decades-old mystery of how tumours form. The new method could help researchers to get more information from tissue biopsies and may lead to improved treatments for pancreatic cancers. The technique was developed by scientists at the Francis Crick Institute.
04/02/2019On February 4th is World Cancer Day. The World Cancer Organization (UICC) launched this day in 2007 to raise awareness of various cancers. This year, the focus lies in particular on the prevention and early detection of cancer. In addition, people will be informed about diagnostic, therapeutic and follow-up options.
04/02/2019Researches from Peter the Great St.Petersburg Polytechnic University (SPbPU), Russian Academic Excellence Initiative participant, in collaboration with the radiologists from St.Petersburg Clinical Research for Specialized Types of Medical Care have developed an intelligent software system for lung cancer diagnostics. It analyzes patients' computed tomography (CT) results within 20 seconds.
01/02/2019Heart muscle cells need exercise - even when they grow outside the human body. A new device designed by U of T Engineering researchers uses a rigorous training regimen to grow small amounts of cardiac tissue and measure how strongly it beats. The platform is ideal for testing the effects of potential drug molecules and could help bring personalized medicine closer to reality.
01/02/2019In vitro processes and animal tests are used to develop new medications and novel therapeutic approaches. However, animal testing raises important ethical concerns. Organ-on-a-chip models promise to be a feasible alternative. In a system the size of a smartphone, organs are connected using artificial circulation.
01/02/2019The liver, nervous tissue or the intestines: all are important human organs that have in the past been tested for their function and compatibility using animal or in vitro test methods. In recent years, TissUse GmbH, a spin-off of the Technical University of Berlin (TU Berlin), has launched multi-organ chip platforms. But that’s not all.
11/01/2019A research team led by investigators from the National Institutes of Health and Global Good has developed a computer algorithm that can analyze digital images of a woman's cervix and accurately identify precancerous changes that require medical attention. This artificial intelligence (AI) approach, called automated visual evaluation.
11/01/2019With the help of sponges inserted in the bloodstream to absorb excess drugs, doctors are hoping to prevent the dangerous side effects of toxic chemotherapy agents or even deliver higher doses to knock back tumors, like liver cancer, that don't respond to more benign treatments.
10/01/2019It's one of the first questions asked by many cancer patients "What are my chances of beating this?" Often there is no clear answer, with survival rates differing widely. Post-operative testing that provides an accurate prediction of long-term treatment outcomes is the next best thing, allowing clinicians to plan further treatment and more accurately inform patients about their prognoses.
08/01/2019Parkinson's disease is a progressive nervous system disorder that primarily affects movement of patients and makes their everyday lives very challenging. It also makes regular doctor appointments and treatment sessions necessary. "TelePark" - a project that collects different movement-related parameters using sensors and apps is designed to improve the quality of life for Parkinson’s patients.
02/01/2019Diabetes mellitus or simply diabetes has become very common and is often described as a lifestyle disease. More and more people are suffering from this chronic metabolic disorder. Next to established diagnostic procedures, digital retinal screening has shown to be successful - a promising technique that will also play an important role in the diagnosis of other diseases in the future.
19/12/2018Continuous monitoring is an essential process with every disease. In the case of eye disorders, frequent retina measurements can facilitate early detection of deterioration to quickly initiate intervention. This calls for comprehensive care settings, easy ways to take measurements and prompt results. However, in reality, this is rarely the case.
17/12/2018Collagen is the fundamental building block of muscles, tissues, tendons, and ligaments in mammals. It is also widely used in reconstructive and cosmetic surgery. Although scientists have a good understanding about how it behaves at the tissue-level, some key mechanical properties of collagen at the nanoscale still remain elusive.
14/12/2018Scientists at Kyushu University and Tokyo Institute of Technology have developed a technique that enables analysis of DNA-protein interactions using very small numbers of cells, ranging from 100 to 1,000. Their method could capture previously unexamined epigenomic information, facilitate biomarker discovery and open new avenues for precision medicine.
14/12/2018Researchers at Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago used a blood test and microarray technology to identify distinct molecular signatures in children with cystic fibrosis. These patterns of gene expression could help predict disease severity and treatment response, and lead to therapies tailored to each patient's precise biology.
13/12/2018To help patients with muscle disorders, scientists at The University of Texas Health Science Center at Houston (UTHealth) have engineered a new stem cell line to study the conversion of stem cells into muscle. Findings appeared in Cell Reports.
11/12/2018Osaka University researchers have developed a system using artificial intelligence that can automatically differentiate between different types of cancer cell.
10/12/2018Tuberculosis of the brain - or tuberculosis meningitis (TBM) - is often deadly, always hard to treat, and a particular threat to young children. It may leave survivors with lifelong brain damage. Now, researchers at Johns Hopkins Medicine report they have used PET scans, a rabbit model and the TB drug rifampin to advance physicians' understanding of this disease.
07/12/2018Scientists at the Max Planck Institute of Molecular Biomedicine in Münster and of the Medical Faculty of the University of Münster have developed a technique that allows the characterisation of the three-dimensional organisation of the DNA in the nucleus directly in patient's cells.
04/12/2018A new study from the University of Iowa finds rural hospitals that use tele-medicine to back up their emergency room health care providers not only save money, but find it easier to recruit new physicians.
04/12/2018A significant shift in the health care market is well underway, with various insurers, medical groups, vendors and supply chains pursuing acquisitions and mergers to expand their services, and retail outlets, from Walmart and Amazon to Rite-Aid and Albertsons, delivering health care services, including telehealth.
03/12/2018Breast cancer survivors who used a smartphone app created at Houston Methodist consistently lost weight, largely due to daily, real-time interactions with their health care team via the mobile app. Few clinically-tested mobile apps exist today with clear measurable goals to support continued care of cancer survivors and patients.
03/12/2018Strengthening and healing thanks to the power of electrical pulses - is that really possible? When mobility is restricted or muscles are no longer as strong as they used to be, electrical treatment options can lead to improvement or even cure of diseases. But why are more and more people turning to these alternatives, what are the advantages and what are their limitations and drawbacks?
30/11/2018A research team from Nanyang Technological University, Singapore (NTU Singapore) and Tan Tock Seng Hospital (TTSH) have invented a smart handheld medical device that could enable early intervention for patients with congestive heart failure.
28/11/2018Investigators at the Martinos Center for Biomedical Imaging at Massachusetts General Hospital (MGH) have used magnetoencephalography (MEG) - a technology that measures brain activity by detecting the weak magnetic fields produced by the brain's normal electrical currents - to measure levels of the iron-based mineral called magnetite in the human brain.
27/11/2018Tablets and other mobile computing devices are part of everyday life, but using them can be difficult for people with paralysis. New research from the BrainGate* consortium shows that a brain-computer interface (BCI) can enable people with paralysis to directly operate an off-the-shelf tablet device just by thinking about making cursor movements and clicks.
26/11/2018Colorectal cancer is the third most common form of cancer in the world. Every year in Finland, approximately 3,000 new cases are diagnosed, and roughly 1,200 patients die of it. Between 2004 and 2016, an extensive screening programme was conducted in Finland, intending to study the potential benefits and downsides of a nation-wide screening for colorectal cancer.
22/11/2018Every year between 250.000 and 500.000 people suffer a spinal cord injury, MoreGrasp is intended to make their lives easier. The project aims to restore the lost gripping function in people with high paraplegia. Researchers at Graz University of Technology have developed a neuroprosthesis that is currently undergoing a feasibility study.
08/11/2018Not enough exercise, an unhealthy diet: Kidney stones develop when urine contains too many insoluble compounds and are now one of the most common diseases worldwide. The ailment annually affects 1.2 million people in Germany alone. The stones are broken up and taken out via endoscopic surgery. Now it’s possible to remove even the tiniest residual fragments. The solution: a biocompatible adhesive.
02/11/2018It’s safe to say that patients and their prompt medical care take center stage at any hospital. Digitization of the healthcare sector is quickly advancing to make this a reality: data is stored in a digital medium, devices are linked together. But how safe are hospitals in the age of innovation?
02/11/2018This is what diagnostic investigation normally looks like: a patient sample is collected, sent to the laboratory and analyzed. Once that's completed, the patient is told of the lab test result. But if the patient is a high-performance athlete and has to follow and stick to a rigid training schedule, he or she needs these results immediately. What makes this possible? Point-of-care testing!
22/10/2018Today’s society is faced with an aging population. The past has seen the development of many methods for measuring body composition in older adults. However, some of these techniques are not available to medical practices and hospital facilities or are in dire need of optimization.
08/10/2018Did you know that we can influence up to 50 percent of our health ourselves? If we eat a balanced diet and exercise regularly, this not only ensures longer independence in old age. Diseases can also be treated with exercise. But in many cases, physicians and patients still rely more on medication than on exercise.
05/10/2018Many people have damaged or suboptimally functioning lungs. An accurate diagnosis and subsequent treatment are vital to protect this life-sustaining organ. Modern imaging solutions help physicians and patients understand what happens inside the lungs.
10/09/2018About eight in ten Germans suffer from back pain during their lifetime. Too much or the wrong movements can also cause problems. "Ran Rücken", the interdisciplinary research project aims to determine the right minimum dose of exercise that proves effective. (Explanatory note: "Ran Rücken" can be loosely translated as "Target the Back")
03/09/2018Artificial intelligence makes the diagnosis, robots perform the surgery and physicians manage all processes via touchscreen – is that what hospitals of the future will look like? And how far away are we actually from this future? Many hospital facilities are already on their way to becoming Smart Hospitals with the latest technology and where everything and everyone is linked and connected.
01/08/2018All of us generate data every day without even realizing it – sometimes it happens unconsciously and unintentionally. At this point, we are made of data and not just in the eyes of tech companies but also from a healthcare system perspective. Our electronic health records are a smorgasbord of data for example.
30/04/2018Medicine is getting more and more personalized. This is particularly interesting for oncology, since a cancer is as individual as the respective patient. When choosing a therapy, both the characteristics of the tumor and the personal characteristics of the patient must be considered. To see exactly what this looks like, we visited the diagnostics company TherapySelect, based in Heidelberg.
23/04/2018A bypass is a complicated structure. It is either made of synthetic materials that can cause blood clots and infections or created by using the patient’s veins. However, the latter often does not yield adequate material. A newly developed bioreactor could solve this problem in the future. It is designed to tissue engineer vascular grafts by using the body’s own material.
01/03/2018Personalized medicine does not follow a "one-size-fits-all" treatment approach but emphasizes a "tailor-made" paradigm, meaning a treatment is customized to each individual person's case. For patients, this increases the chances of treatment success and means fewer side effects. While the approach originates in the field of oncology, it is now also increasingly applied to other disease patterns.
01/03/2018Conventional cancer treatment selection typically depends on the location of the tumor. However, this approach ignores the distinct gene mutations in the tumor of the individual patient. New cancer research approaches increasingly emphasize the concept of personalized therapy.
01/03/2018Everyone is different. This statement also applies to our health. Cancer, in particular, can look and progress differently depending on the individual person. That’s why every patient ideally also needs a customized treatment that is tailored to their individual needs. But how feasible is this idea?
01/08/2017Many therapeutic drugs are very powerful, but they are also very toxic at the same time. Thus, they have to be measured regularly, again and again, so that an adjustment of the individual drug dosage can be made. Until now, the "normal" way was to take the blood sample, send it to a central laboratory and get the results after some days. A new point-of-care test can measure it in 15 minutes.
01/06/2017A stroke, an accident or just because you are aging – there are many reasons to take advantage of physiotherapeutic or rehabilitative measures. More and more new technologies are designed to support patients in this process. They run the gamut from sensor technology and robotics to exergames and virtual reality.
01/06/2017Movement is good for health, but people do it less and less as they age. The Dutch company SilverFit wants to counteract this. Their devices that combine sport and game are primarily aimed at elderly people. Their goal: to give people joy, fun and motivation to move – both in rehabilitation and in daily life.
02/05/2017There are recurring questions that companies are seeking to invest or produce in India. Here are some questions and their answers.
03/04/2017Many aspects are uniformly regulated in Europe, however, hospital hygiene and MRSA prevention, for example, are not. The Netherlands plays a pioneering role in the fight against hospital-acquired infections. The country is an often-cited role model. But can other countries simply adopt the same system? And what makes it so different? MEDICA asked expert Prof. Alexander W. Friedrich.
01/03/2017Genome data, MRI images, and blood test results – data collected in the medical sector is not only very heterogeneous but also extremely extensive. However, it is important to not only collect this data but to also utilize it. After all, processed, linked and analyzed data provides many opportunities in research, hospital management and ultimately also for the individual patient.
01/03/2017In the "KDI – Clinical Data Intelligence Project", researchers are trying to consolidate various types of data to make them useable and useful to both medical professionals and scientists. This is a tremendous undertaking, considering the data volumes from different sources. In this conversation with MEDICA, Dr. Martin Sedlmayr explains the project setup.
12/01/2017Long waiting times in medical practices are not a rarity. The telemedicine can provide remedy. The program of the Institute for Applied Telemedicine at the Heart and Diabetes Center NRW in Bad Oeynhausen is aimed primarily at chronically ill people. Daily, they send their body values via telecommunication to the institute.
02/01/2017Treatments for children need to be different from treatment for adults – this also applies in oncology. Having said that, children do not just need new and different treatment concepts that still necessitate research. They also require the support from their families, who need to be nearby during treatment.