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Image: The microscope image shows mitochondria, the cell's power plants; Copyright: AG Herrmann

Proteins surf to mitochondria – Novel transport pathway discovered

18/09/2018

Prof. Johannes Herrmann, a researcher at the Technische Universität Kaiserslautern, and his team discovered a novel mechanism by which newly synthesized proteins reach their respective target compartment in the cell. Proteins destined to mitochondria, are not directly transported to mitochondria but are directed to the surface of the endoplasmic reticulum.
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Image: Dr. Dao Nguyen looking at Pseudomonas aeruginosa; Copyright: McGill University Health Centre

New means to fight "un-killable" bacteria in healthcare settings

18/09/2018

Scientists at the Research Institute of the McGill University Health Centre (RI-MUHC) have identified new means of fighting drug-tolerant bacteria, a growing global threat as menacing as drug-resistant microbes. Little is known about the mechanisms leading to tolerance, a strategy that makes bacteria "indifferent" to antibiotics and almost "un-killable," which results in chronic infections.
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Image: Bacterial multiplication, which can lead to inflammations; Copyright: panthermedia.net / frenta

New nanoparticles wait to release drugs, target infection

17/09/2018

Current WSU research shows stimuli-responsive nanoparticles can specifically target infections to simultaneously prevent the spread of bacteria and reduce the inflammation it causes. These microscopic particles are loaded with antibiotic and anti-inflammatory agents which are released when the particles encounter infection in the body.
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Image: viral infectivity; Copyright: Lumacyte

New technology transforming vaccine development

13/09/2018

Could we finally have a faster, more objective analytical tool to rapidly measure viral infectivity for vaccine development and production? Scientists and bioengineers at Thermo Fisher Scientific and LumaCyte believe we do. This peer reviewed work is published in the prestigious journal, Vaccine, by Elsevier.
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Image: New tests for secondary heart attack risk; Copyright: Baker Heart and Diabetes Institute

New blood test to screen for secondary heart attack

07/09/2018

A blood test that quickly and easily detects whether a person is at risk of a secondary heart attack is being developed by scientists at the Baker Heart and Diabetes Institute.
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Image: A young man sitting at the curb with a laptop; Copyright: panthermedia.net/DragonImages

$8.8 million for Online HIV prevention program

03/09/2018

The National Institutes of Health (NIH) has awarded an $8.8 million grant to Keep It Up!, a novel online HIV prevention program that has been shown to reduce sexually transmitted infections in gay young men by 40 percent.
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Image: A single UVC light-diffusing optical fiber.; Copyright: David Welch, Ph.D., Columbia University Vagelos College of Physicians and Surgeons

'Safe' UV light may prevent infections

27/08/2018

Optical fibers that emit a type of UV light that's safe for skin--but deadly for drug-resistant bacteria--may be able to prevent infections around skin-penetrating medical devices
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Image: female laboratory assistant at the microscope, man shows her something on a tablet; Copyright: panthermedia.net/matej kastelic

Using big data to predict immunotherapy responses

10/08/2018

In the age of Big Data, cancer researchers are discovering new ways to monitor the effectiveness of immunotherapy treatments.
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Image: graphic showing the function of the nanocarrier; Copyright: Stefan Schuhmacher

Targeting headaches and tumors with nano-submarines

27/07/2018

Scientists at the Mainz University Medical Center and the Max Planck Institute for Polymer Research (MPI-P) have developed a new method to enable miniature drug-filled nanocarriers to dock on to immune cells, which in turn attack tumors. In the future, this may lead to targeted treatment that can largely eliminate damage to healthy tissue.
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Image: person in protective clothing holding the sensor in his hand; Copyright: RMIT University

New detection sensor for type 1 diabetes

19/07/2018

Researchers are developing early detection technology for Type 1 diabetes that can accurately predict if a child is at risk of the chronic disease.
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Image: Three men in suits and a woman in a laboratory coat are standing in a laboratory; Copyright: Ministry of Economy of Mecklenburg-Hither Pomerania/Norbert Fellechner

On the trail of cancer: personalized cancer vaccine

01/03/2018

Conventional cancer treatment selection typically depends on the location of the tumor. However, this approach ignores the distinct gene mutations in the tumor of the individual patient. New cancer research approaches increasingly emphasize the concept of personalized therapy.
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Image: Collage of several MRI images of the heart, in which different locations are marked with red arrows; Copyright: University Hospital Münster/Ali Yilmaz

Myocarditis: more specific diagnosis thanks to molecular imaging

01/09/2017

There are many causes of myocarditis or inflammation of the heart muscle. Oftentimes, the culprits are viruses or bacteria and sometimes even an acute heart attack. Regardless of the cause, it creates a challenge for cardiologists: a diagnosis tends to be only nonspecific without a biopsy. A cardiac MRI and molecular imaging promise to provide assistance.
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Image: A petri dish with yellow bacterial cultures on a black ground; Copyright: panthermedia.net/kwanchaichaiudom

Laboratory medicine: confronting infections with speed and foresight

03/04/2017

The laboratory is one of the most important and pivotal bastions in patient care. In the laboratory, acute, chronic and genetic diseases are diagnosed, the progression of diseases such as diabetes is regularly checked or specialists look for biomarkers to adapt cancer therapies.
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Photo: Child gets pierced into the finger using a lancing device

Diabetes: comprehensive prevention, early "vaccination"?

08/04/2016

A diagnosis of diabetes often catches new patients off guard - for instance if they end up in the emergency room suffering from metabolic decompensation. Children are often affected by this. Their immune system destroys the insulin-producing cells in the pancreas early on in their lives, thus causing type 1 diabetes.
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Cancer Immunotherapy: Individual mutations as new target structures

01/06/2015

A tumor is as unique as the person who is affected by it. For a long time, it was assumed this would make treatment more difficult since cancer drugs are not able to be one hundred percent effective in targeting the affected cells. In this interview with MEDICA.de, Professor Ugur Sahin explains why it is precisely these individual mutations that make him hopeful for a new type of therapy.
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Multi-resistant bacteria want to conquer the world

01/08/2014

Bacteria lurk everywhere: on the skin, in the intestines and in every puddle. Most of them that are hanging out in the human body are good bacteria. But not all of them. Those pathogens that exhibit resistance and are thus very hard to combat are the most dangerous kind. Their spread threatens people all over the world.
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