07/02/201924,000 patients are diagnosed with brain tumors every year with the 5yr survival for high grade glioblastomas (GBM) only 5%, with median survival of 15 months. These poor statistics have remained static for 30 years due in part to a lack of preclinical models for testing new drugs.
05/02/2019Finding the right dose of medication by trial and error can be a painful experience for patients. Thanks to a new algorithm created by Adrien Coulet, lecturer at the Université de Lorraine and researcher in a joint Inria and Loria team, in collaboration with researchers from Stanford University, an innovative tool can predict in advance whether patients will need a lower dose of medication.
04/02/2019On February 4th is World Cancer Day. The World Cancer Organization (UICC) launched this day in 2007 to raise awareness of various cancers. This year, the focus lies in particular on the prevention and early detection of cancer. In addition, people will be informed about diagnostic, therapeutic and follow-up options.
04/02/2019To provide sufficient oxygen to tissues and organs within the body, blood vessels need to sprout new offshoots to form a widespread blood supply network, much like the trunk, branches, and twigs of a tree. However, the mechanisms by which this sprouting occurs, in both normal healthy conditions and in conditions like cancer, have remained unclear.
04/02/2019Researches from Peter the Great St.Petersburg Polytechnic University (SPbPU), Russian Academic Excellence Initiative participant, in collaboration with the radiologists from St.Petersburg Clinical Research for Specialized Types of Medical Care have developed an intelligent software system for lung cancer diagnostics. It analyzes patients' computed tomography (CT) results within 20 seconds.
29/01/2019Natural thermal water that contains radon has been used for over 100 years to treat chronic degenerative, inflammatory and musculoskeletal conditions. Most patients experience a significant reduction in pain after treatment with radon, but the molecular mechanisms behind the treatment are largely unexplored.
24/01/2019Small infections can be fatal: Millions of people die each year from sepsis, an overreaction of the immune system. A new immune signaling molecule, designed by a research team from the Technical University of Munich (TUM), now provides the basis for potential new approaches in sepsis therapy.
22/01/2019Researchers from the Department of Biomedical Research of the University of Bern and the University Clinic of Visceral Surgery and Medicine of the Inselspital Bern, Switzerland, have discovered that changes in the composition of the intestinal bacteria in patients with chronic inflammatory bowel disease affect the severity of the disease and the success of therapy.
21/01/2019In the largest study to date of rapid TB tests used by the NHS, a team led by researchers at Imperial College London found that available tests are not sensitive enough to rule out a diagnosis of TB in suspected cases, and so have limited clinical use.
11/01/2019With the help of sponges inserted in the bloodstream to absorb excess drugs, doctors are hoping to prevent the dangerous side effects of toxic chemotherapy agents or even deliver higher doses to knock back tumors, like liver cancer, that don't respond to more benign treatments.
10/01/2019It's one of the first questions asked by many cancer patients "What are my chances of beating this?" Often there is no clear answer, with survival rates differing widely. Post-operative testing that provides an accurate prediction of long-term treatment outcomes is the next best thing, allowing clinicians to plan further treatment and more accurately inform patients about their prognoses.
09/01/2019Cytomegalovirus is widespread and remains in the body for a lifetime after infection. In healthy individuals, this virus is usually kept in check but can become dangerous when the immune system is weakened or during pregnancy. DZIF scientists at the Helmholtz Zentrum München have developed an analytic method that can very precisely detect viral infections using immune responses.
08/01/2019A research team led by scientists at the Columbia University Mailman School of Public Health report on a new method to help health officials control outbreaks of methicillin-resistant Staphylococcus aureus, or MRSA, a life-threatening antibiotic-resistant infection often seen in hospitals. The researchers demonstrate a new, more effective method to prevent their spread.
20/12/2018Buruli ulcer is a neglected tropical disease (NTD) resulting in debilitating skin lesions, disabilities and stigmatisation. The current antibiotic treatment is long and has severe adverse side effects.
14/12/2018Scientists at Kyushu University and Tokyo Institute of Technology have developed a technique that enables analysis of DNA-protein interactions using very small numbers of cells, ranging from 100 to 1,000. Their method could capture previously unexamined epigenomic information, facilitate biomarker discovery and open new avenues for precision medicine.
11/12/2018Osaka University researchers have developed a system using artificial intelligence that can automatically differentiate between different types of cancer cell.
27/11/2018Elisa Oltra, head of the Genetic Exppression and Immunity group of the Faculty of Medicine at the Catholic University of Valencia (UCV), in collaboration with Alejandro Caicedo, professor of the Department of Medicine of the University of Miami, have developed a surgical process which makes it possible to place functional fragments of the thymus in the anterior chamber of the eyes of mice.
26/11/2018In the era of personalized medicine, scientists are using new genetic and genomic insights to help them determine the best treatment for a given patient. In the case of cancer, the first step toward these treatments is an investigation into how tumor cells behave in an effort to figure out the best drugs to use to attack them.
01/03/2018Conventional cancer treatment selection typically depends on the location of the tumor. However, this approach ignores the distinct gene mutations in the tumor of the individual patient. New cancer research approaches increasingly emphasize the concept of personalized therapy.
01/09/2017There are many causes of myocarditis or inflammation of the heart muscle. Oftentimes, the culprits are viruses or bacteria and sometimes even an acute heart attack. Regardless of the cause, it creates a challenge for cardiologists: a diagnosis tends to be only nonspecific without a biopsy. A cardiac MRI and molecular imaging promise to provide assistance.
03/04/2017The laboratory is one of the most important and pivotal bastions in patient care. In the laboratory, acute, chronic and genetic diseases are diagnosed, the progression of diseases such as diabetes is regularly checked or specialists look for biomarkers to adapt cancer therapies.