30/07/2018A panel of 19 microRNAs identified using next-generation sequencing could categorize indeterminate thyroid nodule samples into malignant and benign. The study was Published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.
27/07/2018A new special issue of SLAS Discovery reflects examples of the recent groundswell of creative new applications for high-throughput flow cytometry (HTFC) in drug discovery.
19/07/2018A team led by the University of California San Diego has developed a chip that can detect a type of genetic mutation known as a single nucleotide polymorphism (SNP) and send the results in real time to a smartphone, computer, or other electronic device. The chip is at least 1,000 times more sensitive at detecting an SNP than current technology.
16/07/2018The rise of genomics, the shift from considering genes singly to collectively, is adding a new dimension to medical care; biomedical researchers hope to use the information contained in human genomes to make better predictions about individual health, including responses to therapeutic drugs.
12/07/2018Like with fingerprints, no two people have the same brain anatomy, a study by researchers of the University of Zurich has shown. This uniqueness is the result of a combination of genetic factors and individual life experiences.
11/07/2018Researchers at the Centre for Genomic Regulation (CRG) in Barcelona developed a new method to systematically identify genes contributing to heritable cancer risk. Their work, which is published in Nature Communications, is a success story for data sharing and openness in science. Just three researchers identified new cancer genes only using publically available data.
05/07/2018New methods of studying the evolution of treatment resistance in head and neck cancer are being developed by researchers at the Johns Hopkins Kimmel Cancer Center. The scientists wanted to examine how cancers acquire resistance to treatment over time and whether those changes could be modeled computationally to determine patient-specific timelines of resistance.
26/06/2018Scientists may now be able to predict whether carrying a specific genetic variant increases a person's risk for disease using gene editing and stem cell technologies, according to new research in the American Heart Association's journal Circulation.
22/06/2018New structural details emerge about one of the body's biggest protein assemblages, the nuclear pore complex.
20/06/2018Around two to six per cent of all people with obesity develop obesity already in early childhood; it's in their genetic cards. Obesity-causal mutations in one of their "appetite genes" gives them a strong genetic predisposition for developing obesity, also called monogenic obesity. Their experience of hunger is overruling and their feeling of satiety limited.
14/06/2018An unexpectedtwo-step mechanism occurs when cells copy DNA.
07/06/2018A new study, affiliated with UNIST has recently presented a novel statistical algorithm, capable of identifying potential disease genes in a more accurate and cost-effective way. This algorithm has also been considered as a new promising approach for the identification of candidate disease genes, as it works effectively with less genomic data and takes only a minute or two to get results.
07/06/2018The researchers investigated faulty versions of a gene called titin which are carried by one in 100 people or 600,000 people in the UK. Titin is crucial for maintaining the elasticity of the heart muscle, and faulty versions are linked to a type of heart failure called dilated cardiomyopathy.
04/06/2018Aging is associated with an increase in frailty and age related-diseases. A calorie-restricted diet is known to alleviate these age-related conditions. Researchers from the ERIBA in Groningen, Netherlands, and the FLI in Jena, Germany, now demonstrate in a mouse model that the C/EBPß-LIP gene regulator is involved in the aging process.
04/06/2018Urine is an everyday liquid which most people pay little attention to and regard as rather unpleasant. It’s quite the opposite for a group of clinical researchers from Kiel University, the University Medical Center Schleswig-Holstein (UKSH) and the Lithuanian University of Health Sciences in Kaunas, who are convinced of the diagnostic potential of this yellowish liquid.
25/05/2018A group of researchers from Graduate School of Pharmaceutical Sciences at The University of Tokyo and Institute of Traditional Chinese Medicine and Natural Products at Jinan University, identified the biosynthetic gene cluster for the furanosteroid demethoxyviridin, and deciphered its biosynthetic pathway.
24/05/2018The transition to modernity – largely driven by the Industrial Revolution – provided us with easier access to food and clean water, with antibiotics, vaccines, and modern medicine. Yet modernity did not just bring fewer infectious diseases and longer life: it also created an environment radically different from the one we evolved in.
01/03/2018Conventional cancer treatment selection typically depends on the location of the tumor. However, this approach ignores the distinct gene mutations in the tumor of the individual patient. New cancer research approaches increasingly emphasize the concept of personalized therapy.
01/03/2018Everyone is different. This statement also applies to our health. Cancer, in particular, can look and progress differently depending on the individual person. That’s why every patient ideally also needs a customized treatment that is tailored to their individual needs. But how feasible is this idea?
01/03/2018Personalized medicine does not follow a "one-size-fits-all" treatment approach but emphasizes a "tailor-made" paradigm, meaning a treatment is customized to each individual person's case. For patients, this increases the chances of treatment success and means fewer side effects. While the approach originates in the field of oncology, it is now also increasingly applied to other disease patterns.
24/07/2017A new analysis method that uses fetal DNA extracted from the mother’s blood is designed to non-invasively reach a prenatal diagnosis of genetic disorders in a child. A task force of the Hahn Schickard Society for Applied Research is an active part of the "ANGELab" project and co-developed this diagnostic procedure.
08/03/2017Pneumonia is the most frequent respiratory disease in children and can even cause death. That is why it is extremely important to make an accurate diagnosis as quickly as possible. If this requires imaging tests, normally X-rays are taken. But there is an alternative: ultrasound.
01/03/2017Genome data, MRI images, and blood test results – data collected in the medical sector is not only very heterogeneous but also extremely extensive. However, it is important to not only collect this data but to also utilize it. After all, processed, linked and analyzed data provides many opportunities in research, hospital management and ultimately also for the individual patient.
01/02/2017Achromatopsia is a rare hereditary visual disorder. Along with total color blindness, patients most notably suffer from reduced visual acuity and increased sensitivity to light and glare.
01/06/2016Until now, plasma, the fourth state of matter,was consideredfascinatingonly to astrophysicists and science fiction fans. But at this point, it also attracts the interest of medicine because plasma can have many uses in this field. In the future, plasma sterilization could become an important component of hospital hygiene-provided that the right device is being used.
08/04/2016A diagnosis of diabetes often catches new patients off guard - for instance if they end up in the emergency room suffering from metabolic decompensation. Children are often affected by this. Their immune system destroys the insulin-producing cells in the pancreas early on in their lives, thus causing type 1 diabetes.
01/04/2016Human genetics is the study of the genetic makeup of human beings. DNA, chromosomes, and genes are extensively analyzed by medical specialists. Physicians of Germany need to have a qualification in genetic counseling to successfully advise patients.
22/02/2016Easy solutions that deliver results quickly are a great asset in medicine: patients receive their diagnosis faster and physicians have more time to treat them. Such tools also work without sophisticated resources and trained personal. A device currently developed in a project funded by the European Commission could bring all of this to point-of-care-testing for infectious diseases.
01/06/2015A tumor is as unique as the person who is affected by it. For a long time, it was assumed this would make treatment more difficult since cancer drugs are not able to be one hundred percent effective in targeting the affected cells. In this interview with MEDICA.de, Professor Ugur Sahin explains why it is precisely these individual mutations that make him hopeful for a new type of therapy.
02/06/2014"Sports are good for your health", as the saying goes. Regular exercise promotes the health of our blood vessels and prevents vascular diseases. However, many years of competitive sports can also have negative effects on vascular health and increase the risk of myocardial infarction. Prof. Martin Halle of the Technical University Munich explains at MEDICA.de what athletes need to pay attention to.