25/05/2018A group of researchers from Graduate School of Pharmaceutical Sciences at The University of Tokyo and Institute of Traditional Chinese Medicine and Natural Products at Jinan University, identified the biosynthetic gene cluster for the furanosteroid demethoxyviridin, and deciphered its biosynthetic pathway.
25/05/2018Macrophages are white blood cells involved in a variety of biological functions, from destroying infectious pathogens to repairing damaged tissue. To carry out their different roles, macrophages must first be activated and transformed into different subtypes. However, the mechanisms that lead to macrophage activation are not fully understood.
24/05/2018The transition to modernity – largely driven by the Industrial Revolution – provided us with easier access to food and clean water, with antibiotics, vaccines, and modern medicine. Yet modernity did not just bring fewer infectious diseases and longer life: it also created an environment radically different from the one we evolved in.
24/05/2018Fibrils of the protein alpha-synuclein, that plays a role in Parkinson's disease, form a stiffer and stronger network in water, when temperature is increased. Researchers of the University of Twente show that this has to do with the water-repellent part of the fibres coming to the surface and interacting.
22/05/2018This unusual ally can be extremely valuable in the fight against inflammation in the body: CO (carbon monoxide). As a therapeutic gas, it also promises relief for inflammatory gastrointestinal diseases. Having said that, it is difficult to transport the active ingredient to the exact desired location.
22/05/2018Stem cells in the brain can divide and mature into neurons participating in various brain functions, including memory. In a paper published in the journal Cell Stem Cell, scientists at Helmholtz Zentrum München and Ludwig-Maximilians-Universität München have shown how this works. They found that ion channels play a key role in mediating force signals to the neural stem cells to activate them.
22/05/2018The way you walk can reveal current and future health problems. New research from Halmstad University suggests the use of wearable sensors for analysing your movement. This can potentially result in early detection of for example Parkinson's disease, dementia, multiple sclerosis and other neuro-physiological disorders.
21/05/2018Researchers at the University of Southampton have developed a new computational way of analysing X-ray images of lungs, which could herald a breakthrough in the diagnosis and assessment of Chronic Obstructive Pulmonary Disease (COPD) and other lung diseases.
21/05/2018Researchers at Tokai, Osaka, Tohoku and Fukuoka Universities report in the journal Communications Chemistry on the synthesis of insulin based on the self-assembly of polypeptide chains at about 40% efficiency.
18/05/2018Protein clumping may contribute to heart failure development and could be used as a diagnostic tool for testing therapies or disease progression.
18/05/2018A little-explored group of immune cells plays an important role in the regulation of intestinal bacteria. Changing metabolic states of the microbes have an effect on defense cells at different stages of alert or rest, as researchers from the Department of Biomedicine at the University and University Hospital of Basel report in the journal Mucosal Immunology.
17/05/2018A neuron model of Parkinson's disease and Lewy body dementias shows defects that could suggest treatments to halt or reverse cognitive impairments before the neurons die.
17/05/2018One gram of fish oil a day could help reduce the pain of patients with osteoarthritis, a new study in Rheumatology reports.
16/05/2018Scientists at the Goethe University have discovered that single cells in the innermost layer of blood vessels proliferate after injury and in so doing make a significant contribution to the formation of new vessels.
16/05/2018Have you ever considered that working night shifts may, in the long run, have an impact on your health? A team of researchers from the McGill University affiliated Douglas Mental Health University Institute (DMHUI) has discovered that genes regulating important biological processes are incapable of adapting to new sleeping and eating patterns.
14/05/2018Megha Padi, Ph.D., of the UA Cancer Center has developed a method for probing the genetic underpinnings of cancer and other diseases, which could lead to better treatments.
14/05/2018Researchers from the Institute for Hygiene and Applied Immunology of the Center for Pathophysiology, Infectology and Immunology at MedUni Vienna, led by Hannes Stockinger, have discovered a hitherto unknown function of the protein lactoferrin, which is primarily found in breast milk.
11/05/2018UH professor of pharmacology Tahir Hussain has received $1.6M from the National Institutes of Health to examine a kidney cell that could prevent damage from inflammation caused by obesity. The targeted cells express a protein called the angiotensin type 2 receptor (AT2R), which recently has been indicated to have anti-inflammatory and reno protective actions.
11/05/2018Asking emergency department (ED) providers to self-identify their opioid prescribing practices and then providing them with timely, clinically relevant, individualized, and actionable feedback on their actual opioid prescribing data, significantly decreases future opioid prescribing among providers who underestimate their baseline prescribing.
10/05/2018Cancer drops sparse chemical hints of its presence early on, but unfortunately, many of them are in a class of biochemicals that could not be detected thoroughly, until now. Researchers at the Georgia Institute of Technology have engineered a chemical trap that exhaustively catches what are called glycoproteins, including minuscule traces that have previously escaped detection.
10/05/2018Clinicians caring for vulnerable babies in the neonatal intensive care unit (NICU) need to closely monitor their vital signs, but precisely gauging the function of their tiny hearts has remained elusive.
09/05/2018Diets rich in nuts, such as walnuts, have been shown to play a role in heart health and in reducing colorectal cancer. According to a new study from the University of Illinois, the way walnuts impact the gut microbiome – the collection of trillions of microbes or bacteria in the gastrointestinal tract – may be behind some of those health benefits.
09/05/2018Young parents who have less education and care for more than one child are more likely to have persistent symptoms of depression that linger six months after their newborn is discharged from the neonatal intensive care unit (NICU), according to a Children's National Health System research presentation during the Pediatric Academic Societies 2018 annual meeting.
08/05/2018Neuropathic pain is the chronic, pathological pain that continues even when the cause of pain is removed. Causes include damage to nerve cells and medicines used to treat cancer. A collaboration between research groups from USA and Finland has discovered a novel therapeutic that appears to interrupt the signaling cascades in the body required for multiple forms of neuropathic pain.
08/05/2018Immune cells that are ready to take action against invaders like bacteria have been found in women's breast milk, researchers say. They say the presence of this SWAT team of immune cells called innate lymphoid cells, or ILCs, in human breast milk is more evidence of the benefits of breastfeeding.
08/05/2018Multidrug-resistant organisms that are treated with a dosage that exceeds the regular dose a hundred times and at temperatures of over 40 degrees Celsius – the human organism is unable to handle it. Yet if the diseased organ is treated outside of the body, extreme conditions are an option. For the first time, physicians have succeeded in treating a severe case of pneumonia by using the OCS.
07/05/2018In education circles, it is widely accepted that minorities are overrepresented in special education. New research from the University of Kansas has found, in terms of autism, minorities are widely underrepresented in special education.
07/05/2018Scientists at The University of Texas at Austin have successfully tested in animals a drug that, they say, may one day help block the withdrawal symptoms and cravings that incessantly coax people with alcoholism to drink. If eventually brought to market, it could help the more than 15 million Americans, and many more around the world who suffer from alcoholism stay sober.
04/05/2018Advances in our understanding of the development and persistence of Obsessive-Compulsive Disorder (OCD) have the potential to improve treatment according to a new study by the University of Waterloo.
04/05/2018Results may open new avenues for treating cardiovascular disease.
03/05/2018UT Southwestern researchers today published in Nature atomic-scale blueprints of the most abundant class of brain nicotinic acetylcholine receptors. A structural understanding of the protein, found in neurons, could lead to new ways to treat nicotine addiction from smoking and vaping.
03/05/2018New algorithm could help overcome shortage of physicians trained in disease diagnosis.
02/05/2018When human movements are no longer as smooth as they should be – due to misalignments or as the result of an injury for example – biomechanical measuring systems spring into action. Thanks to different types of sensors and optical technologies, physicians, therapists, and sports scientists embark on a search for possible causes and corrective options.
02/05/2018For most people with hemophilia B, whose bodies can't properly form blood clots, constant injections to replenish their clotting factors are a way of life.
02/05/2018More than 2 million people worldwide live with inherited and untreatable retinal conditions, including retinitis pigmentosa, which slowly erodes vision.
27/04/2018It sounds like a late-night commercial: In just one hour you can reduce your anxiety levels and some heart health risk factors. But a recent study with 14 participants shows preliminary data that even a single session of meditation can have cardiovascular and psychological benefits for adults with mild to moderate anxiety.
27/04/2018New research has found that poorer well-being or 'health-related quality of life' (HRQoL) in adolescence could be an indicator of future cardiovascular disease risk.
26/04/2018International research consortium led by researchers from the University of Helsinki, Finland, discovered new information related to a rare form of leukemia called aggressive NK-cell leukemia. Potential new treatment options were found which are highly warranted as currently this disease usually leads to rapid death of patients. The study was published in Nature Communications.
26/04/2018"Take a deep breath" is the mantra of every anxiety-reducing advice list ever written. And for good reason. There's increasing physiological evidence connecting breathing patterns with the brain regions that control mood and emotion.
25/04/2018Genetics is a crapshoot. During sexual reproduction, genes from both the mother and the father mix and mingle to produce a genetic combination unique to each offspring. In most cases, the chromosomes line up properly and crossover. In some unlucky cases, "selfish DNA" enters the mix, causing abnormal crossovers with deletions or insertions in chromosomes, which can manifest as birth defects.
25/04/2018A new study from Chalmers University of Technology, Sweden, shines more light on the link between consumption of fish and better long-term neurological health. Parvalbumin, a protein found in great quantities in several different fish species, has been shown to help prevent the formation of certain protein structures closely associated with Parkinson's disease.
24/04/2018Whether or not you develop an allergy is largely dependent upon genetic factors. This is the main finding of a study recently published in EBioMedicine, just in time for World Allergy Week (22-28. April 2018). The study was supervision of Winfried F. Pickl from MedUni Vienna's Institute of Immunology.
24/04/2018Tumor heterogeneity describes the differences between different cells within a given tumor. These differences have major implications for the diagnosis, prognosis, and therapy of cancer patients. Different mechanisms have been proposed to account for tumor heterogeneity such as epithelial to mesenchymal transition (EMT).
23/04/2018A bypass is a complicated structure. It is either made of synthetic materials that can cause blood clots and infections or created by using the patient’s veins. However, the latter often does not yield adequate material. A newly developed bioreactor could solve this problem in the future. It is designed to tissue engineer vascular grafts by using the body’s own material.
23/04/2018The European Immunization Week's general slogan "Prevent. Protect. Immunize" is more relevant than ever in times of globalization and migration. It is a political and structural challenge to give as many people as possible access to vaccination. But even the best care is of no use if the individual does not recognize his or her duty to society.
23/04/2018Using a Raman microscope, researchers at Ruhr-Universität Bochum have studied at which targets the cancer drug Neratinib binds in cells and how its chemical structure changes. Compared with other techniques, this method offers a considerable advantage, as it is not necessary to apply a label to the drug that would indicate its distribution indirectly; rather, the drug itself can be monitored.
23/04/2018Obesity is a world health problem since excessive accumulation of fat tissue (or adipose tissue) increases the risk of cardiovascular disease, hypertension, diabetes and some types of cancer. However, some obese individuals are less susceptible to these conditions.
20/04/2018Researchers led by Nagoya University revealed that deficiency of the innate immune adaptor TRIF significantly shortened survival time of ALS mice.
20/04/2018This project is a result of collaboration of the Organic Chemistry Department and the Biophysics Department at the Lobachevsky University with the Research Institute of Macroheterocyclic Compounds.
19/04/2018The high estrogen levels that typically afford younger women protection from cardiovascular disease appear to instead multiply their risk if they have type 1 diabetes, researchers say.
18/04/2018Stable joint cartilage can be produced from adult stem cells originating from bone marrow. This is made possible by inducing specific molecular processes occurring during embryonic cartilage formation, as researchers from the University and University Hospital of Basel report in the scientific journal PNAS.
18/04/2018Study finds maternal depression negatively impacts a child's cognitive development, infancy through age 16.
13/04/2018The brain continues to put up a fight even as neurodegenerative diseases like dementia damage certain areas and functions. In fact, recent findings in a Baycrest-University of Arizona study suggest that one method the brain uses to counter these diseases is the reassigning of tasks to different regions.
13/04/2018Novel technology developed at UT Health San Antonio gives rise to mouse pancreatic tumors that have the same traits as human pancreatic cancer. A U.S. patent is pending on the invention.
12/04/2018UZH researchers have discovered a new way in which certain antibodies interact with the flu virus. This previously unknown form of interaction opens up new possibilities for developing better vaccines and more efficient medication to combat the flu.
12/04/2018Long-term memory of specific places is stored in the brain in so-called place cells. A team of neuroscientists headed by Dr Andrea Burgalossi of the University of Tübingen's Werner Reichardt Centre for Integrative Neuroscience (CIN) have now 'reprogrammed' such place cells in free-roaming mice, by sending electrical impulses directly to individual neurons.
11/04/2018Researchers from Case Western Reserve University School of Medicine and colleagues have discovered how two brain regions work together to maintain attention, and how discordance between the regions could lead to attention deficit disorders, including schizophrenia, bipolar disorder, and major depression.
11/04/2018A new method enables genes in living T-cells in mice to be modified quickly and efficiently. It makes use of plasmids, a tried-and-tested method of genetic engineering. Researchers from the Department of Biomedicine at the University of Basel and University Hospital Basel reported these findings in the Journal of Immunology.
10/04/2018Human airways already demonstrate gender-based differences in DNA methylation signatures at birth, providing an early hint of which infants may be predisposed to develop respiratory disorders like asthma later in life, a research team reports in a paper published online April 3, 2018, in Scientific Reports.
10/04/2018Hosted by Charité – Universitätsmedizin Berlin, the TrueBrainConnect project aims to systematically study connections between different areas of the brain, and hopes to draw conclusions regarding potential disease patterns.
09/04/2018When a skin lesion is suspected to exhibit malignant changes, it is usually promptly removed. However, not all cases require an excision of the affected tissue. The startup company Magnosco has developed a procedure that uses a laser to support the diagnosis and early detection of malignant melanoma.
09/04/2018In a groundbreaking development, results from a recent clinical trial to treat lung cancer show that a novel immunotherapy combination is surprisingly effective at controlling the disease's progression. The study, published April 4 in the journal The Lancet Oncology, focused on non-small cell lung cancer, which is the most common form of lung cancer.
09/04/2018MPI-P group leader Sapun Parekh and Brown University Professor Nick Fawzi have received $750,000 from the Human Frontier in Science Program (HFSP) over the next 3 years to study the "Structure and biophysics of disordered domains mediating RNP granules: from atoms to cells".
04/04/2018By modifying a muscle transplant operation, Johns Hopkins surgeons report they are able to restore authentic facial expressions of joy -- wide and even smiles - to selected patients with one-sided facial muscle paralysis due to birth defects, stroke, tumors or Bell's palsy.
03/04/2018Findings have major implications for tick-borne diseases like Lyme disease.
03/04/2018In patients with haemophilia A, the missing blood coagulation factor VIII is administered, and thus replaced, intravenously. A part of the patients, however, develops antibodies (inhibitors) against factor VIII, which, in the worst case scenario, can cause uncontrolled bleeding.
29/03/2018Tuberculosis can be cured and could be eradicated. For this to happen, however, patients have to receive the right treatment. Researchers at the Makerere University and the University of Zurich were able to demonstrate that the levels of medication used are often too low. As a result, patients remained contagious with the dangerous disease for longer than necessary.
29/03/2018An international team of researchers has discovered a new anti-cancer protein. The protein, called LHPP, prevents the uncontrolled proliferation of cancer cells in the liver. The researchers led by Prof. Michael N. Hall from the Biozentrum, University of Basel, report in Nature that LHPP can also serve as a biomarker for the diagnosis and prognosis of liver cancer.
28/03/2018The neurodegenerative condition known as Alzheimer's disease is the commonest cause of dementia. A research group led by molecular biologists Fabian Dorninger and Johannes Berger at MedUni Vienna's Centre for Brain Research investigated changes in certain lipids (choline phospholipids) in the plasma of elderly people who were healthy and those suffering from Alzheimer's disease.
28/03/2018Stopping exercise can result in increased depressive symptoms, according to new mental health research from the University of Adelaide.
27/03/2018Patients that underwent weight-loss surgery ran a significantly lower risk of developing severe chronic kidney disease and kidney failure, when compared to conventionally treated patients, according to a study published in International Journal of Obesity.
27/03/2018A team led by biochemistry professor Felix Hausch of the TU Darmstadt is working on substances that are to help fighting three widespread diseases: depression, chronic pain and obesity.
26/03/2018A team from the Research Institute of McGill University Health Centre (RI-MUHC) in Montreal has joined forces with researchers at Johns Hopkins to bring screening and early detection of ovarian and uterine cancers one step closer to clinical implementation. Researchers developed a test that provides a safe and minimally invasive method for earlier diagnosis of ovarian and endometrial cancers.
26/03/2018Mutations have been found in the bassoon (BSN) gene, which is involved with the central nervous system, in patients with symptoms similar to, but different from, a rare brain disorder called progressive supranuclear palsy (PSP).
23/03/2018Women who have a high cardiovascular fitness in middle age have a risk of developing dementia when older that is almost 90 percent lower than among women in average physical condition, according to a study published in the journal "Neurology".
22/03/2018Rare disease also sheds light on normal cell aging, SLU researcher says.
22/03/2018Virtual reality and medicine are increasingly mentioned in the same context. In addition to the development of applications that support the treatment of patients suffering from chronic pain and anxiety, this technology also benefits medical staff. Two months ago, the Ulm University Hospital has opened the VR Lab, where medical students can train and learn with the help of 3D organs.
21/03/2018Recent developments in neuroscience set high requirements for sophisticated data management, not least when implantable Brain Machine Interfaces are used to establish electronic communication between the brain's nerve cells and computers.
21/03/2018Scientists from the "Hopp Children's Cancer Center" at the NCT Heidelberg (KiTZ) and the Neuropathology Department at Heidelberg University Hospital have substantially enhanced the classification of tumors of the central nervous system (CNS).
20/03/2018German Research Foundation extends project aimed at combating multi-resistant Acinetobacter baumannii strains.
20/03/2018UCalgary researchers discover an important clue to help predict disease.
19/03/2018Washington State University researchers have discovered a genetic variation that predicts how well people perform certain mental tasks when they are sleep deprived.
19/03/2018While cognitive abilities naturally decline with age, eating one serving of leafy green vegetables a day may aid in preserving memory and thinking skills as a person grows older, according to a study by researchers at Rush University Medical Center in Chicago. The study results were published in the December 20, issue of Neurology, the medical journal of the American Academy of Neurology.
16/03/2018The accumulation of mutations in the human genome is at the origin of cancers, as well as the development of resistance to treatments. The Cyclin E and Myc genes are active in the control of cell division. When they are mutated, for example in response to a carcinogen, these genes induce cells to start replicating their DNA prematurely during the cell cycle.
16/03/2018Metabolic changes in cells can occur at the earliest stages of disease. In most cases, knowledge of those signals is limited, since we usually detect disease only after it has done significant damage.
15/03/2018Working with cells grown in the lab, Johns Hopkins researchers have identified a biochemical pathway that allows a structure within cells, called the Golgi apparatus, to combat stress caused by free radicals and oxidants. The research team showed that this pathway can be activated by a drug called monensin, which is commonly used as an antibiotic in animal feed.
15/03/2018A newly-discovered hereditary mutation is responsible for an increased production of erythropoietin (EPO) in the blood. This mutation causes a messenger RNA (mRNA) that is not normally involved in the formation of proteins to be reprogrammed so that it produces EPO, thus abnormally increasing the number of red blood cells.
14/03/2018Cardiovascular disease patients have lower levels of an important family of protective molecules in their blood in the morning, which could be increasing their risk of blood clots and heart attacks at those times, according to early research led by Queen Mary University of London.
14/03/2018Brown adipose tissue has played a key role in prevention research since its presence was first documented in adults. However, there was no non-invasive method of measuring its heat generation. A team at the Technical University Munich (TUM) and the Helmholtz Zentrum München has now succeeded in making the activity of brown adipose tissue visible without injecting substances.
13/03/2018A clinical study coordinated by the French National Research Institute for Sustainable Development and Chiang Mai University with their Thai, American, and French partners, strengthens the case for a new strategy to prevent mother-to-child transmission of the hepatitis B virus.
13/03/2018A discovery led by scientists at the University of Alberta and McGill University is providing hope of a new therapeutic target in Multiple Sclerosis (MS) patients, which could one day be used to prevent the symptoms and progression of the disease.
12/03/2018About 1 in 2,500 people have a degenerative nerve disease called Charcot-Marie-Tooth (CMT). The disease is typically diagnosed in children, who can lose their ability to walk and use their hands for fine motor skills. There is no cure – yet.
12/03/2018Scientists on the Norwich Research Park have discovered a key mechanism by which gut bacteria colonise and adhere to their specific hosts. The finding may lead to new, improved probiotics with optimised abilities to colonise our gut and battle infections by forming strong associations with the host as biofilms.
09/03/2018Scientists identify a natural brake on the allergic attack.
09/03/2018Victims are not necessarily on a path towards poor health in adulthood.
08/03/2018There are currently an estimated 1.8 million people in Germany who have atrial fibrillation but do not know it. Now a Dutch company has developed an app with which a smartphone can be used to detect this dangerous cardiac arrhythmia. Scientists at the TU Darmstadt are helping to ensure the recorded data is interpreted correctly and efficiently.
08/03/2018Researchers at the Emory Rollins School of Public Health and U.S. Centers for Disease Control and Prevention have found that high proportions of patients with prediabetes are at substantial risk for cardiovascular disease and chronic kidney disease. Their findings are published in "The Lancet Diabetes & Endocrinology".
08/03/2018Automation makes work life easier in many ways but is it also a solution for analyzing medical images? Is a computer actually reliable enough to assist in the medical decision making process? Researchers in Landshut examine how machine learning algorithms can work more reliably and support radiologists.
07/03/2018A research describes the anti-cancer effects of a natural alkaloid extracted from Daffodils. Led by Denis Lafontaine, affiliated with the Faculty of Sciences at the ULB, the researchers have discovered that this compound triggers the activation of an anti-tumoral surveillance pathway.
07/03/2018The study shows that blockade of the protease MT4-MMP increases the activity of blood-patrolling monocytes in the circulation.
06/03/2018By examining the cornea of the eye with a special microscope it may be possible within ten minutes to diagnose if a person with type 2 diabetes has nerve damage. This according to a study among diabetics in Skellefteå, north Sweden.
06/03/2018Physicists have devised a new method of investigating brain function, opening a new frontier in the diagnoses of neurodegenerative and ageing related diseases.
05/03/2018For seven years as a graduate student at Montana State University, Rebecca Hochstein hiked into the backcountry of Yellowstone National Park.
05/03/2018Prenatal exposure to male hormones influences which activities girls are interested and engage in, but the effects of those hormones don't extend to gender identity or who they socialize with, according to Penn State researchers.
02/03/2018A bone marrow transplant is often the only therapy available to save leukaemia patients, but the risk of complications is high. In spite of devoting considerable time and effort to finding a suitable donor, nearly half of all patients experience an unwanted reaction of their immune system, which often attacks their skin and liver and in up to 50% of cases the intestines.
02/03/2018UZH researchers have discovered a previously unknown way in which proteins interact with one another and cells organize themselves. This new mechanism involves two fully unstructured proteins forming an ultra-high-affinity complex due to their opposite net charge. Proteins usually bind one another as a result of perfectly matching shapes in their three-dimensional structures.
01/03/2018Academy Professor Riitta Lahesmaa’s research group from Turku Centre for Biotechnology of the University of Turku and Åbo Akademi University, Finland, has discovered a new regulator of the immune system, a key factor that controls development of regulatory T cells.
01/03/2018People suffering from major depressive disorder, MDD, have reduced arginine levels, a new study from the University of Eastern Finland shows. Arginine is an amino acid which the body uses to produce, e.g., nitric oxide. Nitric oxide, in turn, is a nervous system and immune defence mediator, and it also plays a role in vascular regulation.
01/03/2018Conventional cancer treatment selection typically depends on the location of the tumor. However, this approach ignores the distinct gene mutations in the tumor of the individual patient. New cancer research approaches increasingly emphasize the concept of personalized therapy.
01/03/2018Personalized medicine does not follow a "one-size-fits-all" treatment approach but emphasizes a "tailor-made" paradigm, meaning a treatment is customized to each individual person's case. For patients, this increases the chances of treatment success and means fewer side effects. While the approach originates in the field of oncology, it is now also increasingly applied to other disease patterns.
01/03/2018Everyone is different. This statement also applies to our health. Cancer, in particular, can look and progress differently depending on the individual person. That’s why every patient ideally also needs a customized treatment that is tailored to their individual needs. But how feasible is this idea?
28/02/2018The bacterium Streptomyces chartreusis is an antibiotic-producing bacterium that releases more metabolites into the surrounding medium than scientists assumed based on the analysis of the genome. Many of the substances are likely released to mediate interactions with its environment. They might also include molecules that are of interest as potential pharmaceutical agents.
27/02/2018The Women's Health Initiative found that hormone therapy (HT) use was associated with a reduction in vertebral fracture risk. A new study shows these same benefits may also guard against a woman's risk of developing hyperkyphosis, an exaggerated curvature of the spine that creates a forward stooped posture.
27/02/2018Key repeating moments in the film give viewers the information they need to understand the storyline. The scenes cause identical reactions in the viewer's brain. The results deepen our understanding of how the brain functions, how narratives work in film, and memory mechanisms impaired by conditions such as Alzheimer's disease.
26/02/2018Constrictions of the coronary blood vessels is a possible consequence of type 1 diabetes, and one that can eventually lead to myocardial infarction or heart failure. Generally speaking, women are afflicted by coronary artery disease later than men, but if a woman has type 2 diabetes, the advantage is negated.
26/02/2018Bacteria-killing viruses could be employed not just in health care, but also in the food industry, a study conducted at the University of Helsinki indicates. The researchers have been investigating the possibility of utilising phages in eradicating foodborne pathogens and preventing food poisoning.
22/02/2018Here on Earth, all experiments are bound by gravitation. Yet, freed from gravity's grip, tumor cells, for example, behave in an entirely different way. As part of the "Thyroid Cancer Cells in Space" project by the University of Magdeburg, smartphone-sized containers carrying poorly differentiated thyroid cancer cells are sent into space.
08/02/2018When body tissue is reconnected during a tumor operation in the gastrointestinal tract, surgeons need information about the current state of these so-called anastomoses. The new, non-invasive hyperspectral imaging technology now makes it possible to measure the crucial parameters during surgery and thereby increase surgical precision.
22/01/2018Research does not always occur in laboratory settings. As part of citizen science, citizens collect data and make it available for research projects. Now, this approach is also adopted in medicine by way of patient science: in a new project, patients take part in cystic fibrosis research. The goal is to improve the lives of those who are affected by this chronic disease.
08/01/2018Few patients with heart failure are fortunate enough to receive a donor's heart. Ventricular assist devices (or heart pumps) have been around for several years and are designed to buy time as patients wait for a transplant. Unfortunately, the body doesn't always tolerate these devices.
04/01/2018While it is commonplace for operating room staff to work together as a team, the collaboration of operating room systems does not always work so well – many devices are still separated from one another, causing the OR processes to be prone to mistakes. The same applies to surgical navigation technologies that represent the interface between imaging, the surgeon and therapeutic devices.
20/12/2017Sixty percent of newborns are affected by jaundice during their first days of life. In most cases, the condition is harmless. The ailment is more pronounced in premature babies, whose treatment involves irradiation with blue light in a special incubator – naked and alone.
22/11/2017Human trafficking is a global crime that often preys on underage persons and forces them into prostitution and forced labor. In most cases, people are smuggled across borders with fake passports. Scientists at the Fraunhofer IBMT have now developed a non-invasive, handheld smartphone-compatible scanner that uses ultrasound to determine whether a person has reached full legal age.
08/11/2017Major surgeries in the abdominal region often result in kidney injury in patients. Meanwhile, the clinical manifestations don't present until one or two days after the procedure. This causes physicians to lose valuable time to treat patients. The University Hospital Regensburg has researched a new concept for the treatment of kidney injuries for several years.
23/10/2017According to the WHO, 300 million people throughout the world are affected by lymphedema. This condition occurs when fluid that flows between cells is no longer transported back into the blood circulation and accumulates in the skin. Triggers can be surgeries, injuries or genetic defects for example. A new microscopy technique could now also indicate the causes.
09/10/2017Whole-body electromyostimulation (WB-EMS) promises time-efficient muscle strength training that has positive effects after just a few sessions per week. Its objective is a fast increase in muscle mass and reduction of body fat. Can WB-EMS training replace conventional strength and endurance training? And can it help to prevent diseases or pain?
02/10/2017If you are interested in laboratory medicine and come to the MEDICA 2017, you will quickly notice that Exhibition Halls 1 and 2 were demolished. A new state-of-the art hall is meant to take their place. Until then, exhibitors from the field of laboratory medicine will be showcased at their temporary new location in the lightweight hall structures 3a and 18 on the fairgrounds.
22/09/2017Many people all over the world suffer from myopia, also known as nearsightedness. A severe elongation of the eyeball is the cause behind it. If it continues to progress, it ultimately leads to complete loss of vision. Now an innovative medical device intends to stop this progression in the future.
01/09/2017There are many causes of myocarditis or inflammation of the heart muscle. Oftentimes, the culprits are viruses or bacteria and sometimes even an acute heart attack. Regardless of the cause, it creates a challenge for cardiologists: a diagnosis tends to be only nonspecific without a biopsy. A cardiac MRI and molecular imaging promise to provide assistance.
22/08/2017Physics has always supported medical science, especially when it comes to practical implementation. Now physicists and health professionals join in collaborative research at an interdisciplinary Center in Erlangen and incorporate fundamental principles of theoretical physics in their studies of diseases.
08/08/2017For centuries, scientific research has succeeded by chronicling experiments with pinpoint accuracy. Yet despite all the progress in the actual laboratory, recording is often still done manually, in notebooks, logs or computer systems for instance. In the future, a gesture recognition system could perform this task for scientists.
01/08/2017An increasing percentage of the world population suffers from chronic inflammatory disorders of the respiratory system. Acute attacks often lead to a worsening of the disease and considerably reduce the patient’s lung volume. Nine institutes of a research alliance under the Leibniz Institute umbrella are working on technologies designed to predict and thus prevent exacerbations.
01/08/2017Many therapeutic drugs are very powerful, but they are also very toxic at the same time. Thus, they have to be measured regularly, again and again, so that an adjustment of the individual drug dosage can be made. Until now, the "normal" way was to take the blood sample, send it to a central laboratory and get the results after some days. A new point-of-care test can measure it in 15 minutes.
24/07/2017A new analysis method that uses fetal DNA extracted from the mother’s blood is designed to non-invasively reach a prenatal diagnosis of genetic disorders in a child. A task force of the Hahn Schickard Society for Applied Research is an active part of the "ANGELab" project and co-developed this diagnostic procedure.
10/07/2017Radiation therapies are an essential component of today’s oncology because they enable the treatment of localized tumors. Yet they have one major drawback: radiation damages not just tumor cells but also healthy tissue. One solution to solve this problem could be proton minibeam therapy, which uses finely focused beams.
22/06/2017The doctor's profession is exhausting and involves many different activities. For a long time, there have been discussions about how doctors can be supported by other specialists. One solution: help from so-called physician assistants.
08/06/2017After earthquakes or other types of disasters, infrastructures are often damaged and local hospitals destroyed. A modular hospital, developed under the direction of the European Commission’s Humanitarian Aid and Civil Protection Department is designed to be ready for these types of disaster situations and support the emergency response.
01/06/2017After a stroke or as a result of aging, there are many situations when people are impaired in their walking ability and rely on a personal assistant or auxiliary aids and services. The XoSoft Project offers a solution: a soft exoskeleton that can be worn like a pair of leggings and stiffens or softens, depending on the situation.
22/05/2017For many years, cochlear implants have restored a sense of hearing in people with certain types of hearing loss. For surgeons, the implantation requires a precise attention to detail under the microscope. The results for the patients improve significantly with a more precise placement of the electrode array. The use of a surgical robot can increase the accuracy of the procedure.
08/05/2017How can emergency room associates continue to educate themselves in a fast manner and without bureaucratic hurdles? The A.L.I.N.A Project, which gives associates new tools with special assistance services and learning environments, delivers the solution. We spoke with Prof. Sabine Blaschke at the University Hospital Göttingen about these tools and how they work.
02/05/2017India is a land of contradictions. On the one hand, it has densely populated cities with state of the art technology. On the other hand, two-thirds of the population still live under challenging hygienic and financial conditions in the rural areas. Despite these conditions or perhaps because of them, more and more medical technology companies from all over the world are interested in this market.
02/05/2017When it comes to the production and development of tech products, many people immediately think of Germany, Japan, the U.S. or Taiwan. What’s often unknown is that an emerging market like India also offers great potential. After all, the country has a large number of experts and just as much technical knowledge at its disposal.
24/04/2017Liver cancer is the fifth most common malignant tumor in the world. The tumor can be removed through surgery or by utilizing thermal ablation techniques. If a treatment with conservative methods is no longer possible, there is an alternative: irreversible electroporation (IRE). The effectiveness of this method was now confirmed by a clinical study.
10/04/2017People with hip osteoarthritis often suffer from severe pain and only an endoprosthesis implantation can provide relief. This involves a major intervention and long-term rehabilitation because the implant requires the removal of a section of the thigh bone. The "MioHIP" research project looks for an elastic alternative.
03/04/2017Instant treatment is absolute vital for patients developing sepsis. Providing a specific therapy early on is key. To manage this the pathogenic organisms need to be identified accurately. But a fungal sepsis can still be a hard nut to crack.
03/04/2017Many aspects are uniformly regulated in Europe, however, hospital hygiene and MRSA prevention, for example, are not. The Netherlands plays a pioneering role in the fight against hospital-acquired infections. The country is an often-cited role model. But can other countries simply adopt the same system? And what makes it so different? MEDICA asked expert Prof. Alexander W. Friedrich.
03/04/2017The laboratory is one of the most important and pivotal bastions in patient care. In the laboratory, acute, chronic and genetic diseases are diagnosed, the progression of diseases such as diabetes is regularly checked or specialists look for biomarkers to adapt cancer therapies.
01/03/2017In the "KDI – Clinical Data Intelligence Project", researchers are trying to consolidate various types of data to make them useable and useful to both medical professionals and scientists. This is a tremendous undertaking, considering the data volumes from different sources. In this conversation with MEDICA, Dr. Martin Sedlmayr explains the project setup.
22/02/2017Surgeons need a great sense of touch. They first have to acquire this skill in simulation training before they can perform surgery on actual patients. Having said that, simulators are not just meant to teach the right movements; ideally, they should also provide a true-to-life experience of the surgical field – as is the case in RealSpine surgical training.
08/02/2017Listening to your favorite music for at least 90 minutes a day and treating your tinnitus with it? Almost sounds too good to be true. Yet more and more German statutory health insurance providers pay for this treatment. We wanted to know more about it and spoke with Jörg Land, the CEO of Sonormed GmbH, about Tinnitracks.
01/02/2017Using stents to treat glaucoma is not a new procedure but they have not been implanted into patients on a regular basis until only recently. But this is about to change, which is why MEDICA.de asked what these glaucoma mini-stents are able to do and who may be a good candidate for them. Professor Norbert Pfeiffer answered our questions.
01/02/2017Achromatopsia is a rare hereditary visual disorder. Along with total color blindness, patients most notably suffer from reduced visual acuity and increased sensitivity to light and glare.
02/01/2017Treatments for children need to be different from treatment for adults – this also applies in oncology. Having said that, children do not just need new and different treatment concepts that still necessitate research. They also require the support from their families, who need to be nearby during treatment.
21/12/2016Within the scope of the VIRUSCAN project that is funded by the Horizon 2020 Research and Innovation Program of the European Union, Dr. Charlotte Uetrecht from Hamburg/Germany investigates individual viruses to be able to later identify them on a nanospring structure. MEDICA.de wanted to know: how does this work?
08/12/2016Watching millions of neurons in the brain interacting with each other – for a long time this was possible only to a limited extent. The current techniques can visualize only superficial layers or the imaging they use is too slow. But now, Prof Daniel Razansky and his team have found a new method to visualize the brain activity – by using optoacoustics.
22/11/2016It happens about 1,800 times per year: after a sporting or traffic-related accident, a person’s spinal cord is injured to where nerve tracts are severed and he/she becomes paralyzed. Researchers now want to develop software that measures the brain signals of paralyzed patients and sends out electrical impulses via a system to stimulate muscles, causing them to move again.
02/11/2016Call systems: every hospital patient is familiar with them, but hardly anyone gives any thought to how they work. And yet they fulfill an important function because in an emergency, they "call" for help. Just think what might happen if they didn’t work. That is why they are subject to stringent safety regulations. We spoke with D.Eng. Matthias Rychetsky, who is familiar with call systems.
04/10/2016So far, avatars could only be found in computer games. But if researchers of the EU-wide www.myhealthavatar.eu project have their way, this could soon change.
04/10/2016Chronic inflammatory bowel diseases like Crohn’s disease and ulcerative colitis increasingly develop at a younger age and affect patients for life. Regular check-ups need to occur every two to three months. Now, a specially designed app intends to provide relief.
08/09/2016For many patients, the start of hemodialysis marks the lifelong dependency on needing their blood purified. But before they can actually begin treatments, a blood vessel in the patient's arm needs to be enlarged to where it can move enough blood and withstand being connected to the dialysis machine several times per week.
01/09/2016Patients take center stage during surgery. Their treatment should be as gentle and effective as possible, which is why there is a trend towards minimally invasive surgery (MIS). But minimal procedures require better supporting technologies. The hybrid operating room combines surgery and imaging systems and increasingly replaces conventional open surgery approaches with MIS.
22/08/2016A beautiful field of flowers, a trip to the beach or a visit to the zoo. Children can experience all of these at the Clinical Center Dortmund in a 270- degree projection on the wall. The Center created a space that is designed to help its little patients overcome their fear of MRI scans.
08/08/2016What happens when stem cells differentiate? What molecular characteristics do they have? Questions that can now be easier answered with the help of a new open-source software. We spoke with Prof. Fabian Theis at the Helmholtz Center Munich, who participated in the software development.
22/07/2016Millions of people all over the world suffer from partial blindness – caused by glaucoma, a stroke or traumatic brain injury. For years, the loss of vision was deemed irreversible. But now a new treatment makes it possible to improve eyesight and vision.
08/06/2016Just a few minutes can make the difference between life and death when a person loses consciousness or goes into sudden cardiac arrest. Unfortunately, emergency medical services cannot always be on location as fast as needed. To ensure immediate life-sustaining measures, the "mobile rescue" app was developed, which alerts emergency medical responders in the immediate vicinity of an emergency.
01/06/2016Some hospitals have long banned the status symbol of physicians – the white coat. Research has shown that especially the sleeves were contaminated with various types of bacteria. But it’s not just lab coats that can spread germs in healthcare settings. This field uses a variety of different textiles. Wouldn’t it, therefore, make sense to apply antimicrobial finishes?
22/05/2016The treatment for diabetes is very time-consuming for patients: they need to regularly monitor blood sugar levels, take medication and inject insulin. Poor self-management may result in a dangerous lapse in blood glucose levels. Yet external factors can also contribute to diabetes being out of control. An artificial pancreas system could offer relief.
02/05/2016Heart failure or cardiac insufficiency presents an extra strain on patients because it severally limits everyday performance and deprives them of energy. Due to their intense need for movement, children are particularly strongly affected. However, the disease is frequently not detected until the physical performance is already declining. An early diagnosis could prevent this.
22/04/2016How can you print ceramics, what purpose do they have and how benefits medical technology? Answers provides Dr. Tassilo Moritz from Fraunhofer Institute for Ceramic Technologies and Systems IKTS.
22/03/2016Medical apps like diabetes or high blood pressure diaries are becoming increasingly popular with smartphone users. There are many available choices out there but they are not always clear. Added to this is the question of how the data collected by the apps can be sensibly incorporated into treatment.
08/03/2016Pancreatic cancer is one of the deadliest forms of cancer because it is difficult to diagnose and only presents with symptoms in the later stages. In the future, a laboratory test developed at the Greifswald University Medicine could make an early detection of this type of cancer and consequently a faster and better treatment possible.
22/02/2016Easy solutions that deliver results quickly are a great asset in medicine: patients receive their diagnosis faster and physicians have more time to treat them. Such tools also work without sophisticated resources and trained personal. A device currently developed in a project funded by the European Commission could bring all of this to point-of-care-testing for infectious diseases.
09/02/2016Many people suffer from atherosclerosis, especially in developed countries. The buildup of fatty deposits inside the arterial blood vessels leads to strokes and heart attacks. Now, a new method is designed to get to the root of the problem, and with the help of nanoparticles inject new turbo replacement cells into the blood vessels which are intended to exert their curative effect.
22/01/2016It may fits, but somewhere it still tweaks. Although a suit off the rack serves its purpose, it is still far from being an ideal solution. With a custom made heart it is different. It is similar with implants. Often patients complain about the fact that those implants feel strange. 3D printing is on the best way to change this. Here, the implants are adapted to the carrier.
08/01/2016There are various artificial heart valves available for children, but they have one essential drawback: they need to be replaced because the children are still growing. The artificial valve, on the other hand, remains the same size – and subsequently becomes too small. This is why an artificial heart valve that grows over time would be ideal.
04/01/2016Most Europeans think it was a long time ago, but the residents of West Africa clearly feel the consequences of the Ebola epidemic that broke out in December 2013 and still continues today. So far, approximately 11,300 people have died as a result of the outbreak; more than 28,000 contracted the disease.
01/12/2015If you could stimulate brain cells to grow in a specific direction, you would probably be able to achieve a significant improvement in the health of patients suffering from Parkinson’s disease. This is why the MAGNEURON project focuses on this approach. The EU is funding the project with approximately 3.5 million Euros.
02/11/2015Minimally invasive surgeries are gentler on the patient but have one distinct disadvantage for the surgeon: he is not able to interact directly with the operating field. Sometimes he misses impressions that are very important to the success of the intervention. The MiroSurge robot for surgical applications which transmits feedback to the surgeon can help.
01/10/2015Semiconductor nanoparticles for biomedical applications have been researched for some time now. Not only are they millionths of a millimeter in size, they also offer great potential for cancer diagnostics and therapy, so-called theranostics. They enter cells, are activated by ultrasonic radiation and destroy the cells using the generated vibration.
01/10/2015It is a portmanteau, a mixture of two words. This way it saves us time and trouble while speaking because the human speech apparatus is lazy. And it describes a mixture of procedures: the combination of two procedures that would normally be separate in medicine. We are talking about theranostics.
01/09/2015They can be seen everywhere: at the wrists, in the ear, clipped to the belt. Wearables are small technical assistants who are built to collect and partially also to analyze data. Some of them collect measurable health data, others "only" count their user’s steps or measure the surrounding UV radiation. The fact is, however, that wearables are en vogue and are used for many different cases.
03/08/2015Malignant tumors can be fought with X-rays – usually with radiation therapy from outside the body. Nuclear medicine physicians can also accomplish this inside the body with radioactive materials, called radiopharmaceuticals. They also offer big benefits for clinical diagnostics as long as a specific target can be assigned to them.
01/07/2015When measuring myocardial activity, it is important for the skin to always stay moist under the electrodes of the ECG. Only then can data be consistently transferred. Athletes have an easier time with this: they are used to sweating. This is a lot harder for older patients.
01/06/2015When cancer is diagnosed, the terms tumor markers or biomarkers keep popping up. They describe characteristics that are not found in healthy persons. The classic tumor markers can be easily detected in blood samples or other body fluids. Other analysis methods require more effort. Yet they all share one thing in common: biomarkers indicate a potential tumor.
01/06/2015A tumor is as unique as the person who is affected by it. For a long time, it was assumed this would make treatment more difficult since cancer drugs are not able to be one hundred percent effective in targeting the affected cells. In this interview with MEDICA.de, Professor Ugur Sahin explains why it is precisely these individual mutations that make him hopeful for a new type of therapy.
04/05/2015Since the end of April 2015, the long-awaited evaluation report on the skin cancer screening programs offered by German health insurance providers is now finally available. We spoke with Dr. Ralph von Kiedrowski, Board Member of the German Dermatologist Association (German: Berufsverband Deutscher Dermatologen) on what the screening can accomplish and his take on the G-BA report.
02/03/2015How should a hospital best respond to an emergency and which types of crises should it be prepared for? We spoke with Professor Ronald Glasberg at the SRH Hochschule Berlin on this subject.
02/02/2015Only projects with a solid foundation are successful in the long run. This is also true for science. Biobanks are the most important component of this foundation when it comes to fundamental biomedical research: Only high quality tissue samples that are stored there make conclusive research possible - for example in search of the causes of tumorigenesis.
05/01/2015T-cells are the guardians of our immune system. When they show changes, it can lead to severe inflammatory responses in the body. It is believed that the T-cells in persons who are affected by inflammatory bowel disease don’t work properly. Two proteins that can be found on activated T-cells and that interact with each other are now being analyzed.
01/12/2014How does a physician handle a patient, who wants to die and what rights do I actually have as a patient? Legal practitioners do not automatically answer these and other questions. We talked about this subject with MD-PhD Ralf Jox from the Institute of Ethics, History and Theory of Medicine at the Ludwig Maximilians University of Munich, Germany.
03/11/2014As an imaging procedure, magnetic resonance tomography has become essential in clinical practice, since it can easily make organs and tissue visible. However, until now abnormal cancer cells or small centers of inflammation remained almost invisible. Now cell biologists from Berlin, Germany, have succeeded in fixing this problem with xenon magnetic resonance imaging.
03/11/2014The treatment of chronic wounds is extremely problematic. Chronic wounds can take months or years to heal and some even never heal resulting in over 100.000 amputations taking place annually in the US alone. A new technology from Iceland, that is based on fish skin and is already used clinically, allows for improved healing of chronic and burn wounds.
01/10/2014On November 10, 2014, astronaut Alexander Gerst will return to Earth from the International Space Station (ISS). He is not just anxiously expected by his family, but also by Dr. Anna-Maria Liphardt from the Institute of Biomechanics and Orthopedics at the German Sport University Cologne
01/09/2014The public only notices diseases when celebrities become patients: in the spring of 2014, Formula One driver Michael Schumacher fell into a coma for several months as the result of a head injury caused by a skiing accident. These types of accidents show how delicate the brain responds to injuries. Brain stimulation could possibly support the rehabilitation of vegetative patients.
01/09/2014When very young children already need to be in the operating room, it’s not just the parents that are concerned. This type of situation is a special challenge for the entire operating team, because children are always very special patients - especially since they are not just simply small grown-ups!
01/07/2014In patients with Parkinson's, neural cells in the brain die off that produce the neurotransmitter dopamine. Certain physical symptoms that can indicate the disease follow years later. But a reliable diagnosis can only be made through examination of the brain after the patient's death, and not during his lifetime.
01/07/2014The not so popular “love handles“ could revolutionize medicine in the near future. In cooperation with the University of Rostock (Professor Hermann Seitz), the human med AG Company currently seeks to develop a device that is able to gently remove adipose tissue during surgery and subsequently isolate stem cells.
02/06/2014When are sports healthy, how often should you engage in sports and what effect do sports have on the body – over the past few decades, there were always different answers to these questions. Many studies that were conducted in the past however confirm the assumption that sports and exercise always support health, even if someone is already sick.
02/05/2014Staying active and mobile when you are old – who doesn’t want that? People suffering from dementia can often only dream about that. The fear of not finding your way back home or not getting any help in an emergency severally restricts many affected people in the way they live their lives. Yet there are many people, who could still independently participate in life despite mild dementia.
04/03/2014Continuing education is an integral part of the medical profession, because research continuously delivers new findings that sooner or later make their way into patient treatments. How does an event need to be organized to provide the highest level of benefit for the participants? MEDICA.de spoke with Eva Ningel, Managing Director for beta seminare bonn berlin GmbH (bsbb).
03/02/2014Radiologists usually do their work after oncologists when it comes to cancer treatment. Yet modern radiology also provides treatments at this point. MEDICA.de spoke with Professor Stefan Schönberg, Director of the Institute of Clinical Radiology and Nuclear Medicine at the University Medical Center Mannheim, Germany, about the use of a new computer tomograph and its benefits for patients.
06/01/2014Whether a surgical suture is better applied manually or with a surgical stapler can be determined through trial and error. Determining which method guarantees patient safety best should also not just be based on a surgeon’s experience. Controlled studies are the method of choice to assess both well-proven and new techniques in the operating room.
06/01/2014Even medical risk products are not always tested as thoroughly as would be necessary – be it because of criminal energy, lack of know-how or financial reasons. A revision of clinical trial procedures could not only fix loop holes and methodological flaws. Products and methods could also be brought into general medical care more quickly under new rules.