10/08/2018In the age of Big Data, cancer researchers are discovering new ways to monitor the effectiveness of immunotherapy treatments.
10/08/2018A space-exploring robot crashes on a distant planet. In order to gather the pieces of its damaged spaceship, it needs to build emotional rapport with the local alien inhabitants. The aliens speak a different language but their facial expressions are remarkably humanlike.
08/08/2018Researchers at the University of Zurich have developed a novel method for analyzing cells and their components called Iterative Indirect Immunofluorescence Imaging (4i). This innovation greatly refines the standard immunofluorescence imaging technique used in biomedicine and provides clinicians with an enormous amount of data from each individual sample.
08/08/2018Some solutions are simple, though not necessarily obvious. The WAKE-UP study, which included 70 participating European stroke centers, has now studied a relatively simple procedure to manage the acute care of stroke patients and avoid potential long-term effects. Best of all, it is available wherever MRI is offered.
07/08/2018A technology designed to treat injured warfighters on the battlefield is proving its worth to civilian emergency-response teams.
07/08/2018In a recently published study in the journal Nature Microbiology, researchers at Los Alamos National Laboratory show that computer simulations can accurately predict the transmission of HIV across populations, which could aid in preventing the disease.
06/08/2018Researchers have discovered a new nuclear medicine test that could improve care of patients with type 1 diabetes. The new positron emission tomography (PET) imaging method could measure beta-cell mass, which would greatly enhance the ability to monitor and guide diabetes therapies. This study is reported in the featured article of the month in The Journal of Nuclear Medicine's August issue.
27/07/2018Scientists at the Mainz University Medical Center and the Max Planck Institute for Polymer Research (MPI-P) have developed a new method to enable miniature drug-filled nanocarriers to dock on to immune cells, which in turn attack tumors. In the future, this may lead to targeted treatment that can largely eliminate damage to healthy tissue.
27/07/2018A new special issue of SLAS Discovery reflects examples of the recent groundswell of creative new applications for high-throughput flow cytometry (HTFC) in drug discovery.
26/07/2018An international collaborative study between Lawson Health Research Institute, Memorial Sloan Kettering Cancer Center, the Royal Marsden and Epic Sciences is one of the first to demonstrate that a blood test can predict how patients with advanced prostate cancer will respond to specific treatments, leading to improved survival.
26/07/2018Fitness trackers can be valuable tools for assessing the quality of life and daily functioning of cancer patients during treatment, a new study has found. The trackers, also known as wearable activity monitors, include commercial devices worn on the wrist that log a wearer's step counts, stairs climbed, calories, heart rate and sleep.
25/07/2018A new study, presented at the Society of NeuroInterventional Surgery's (SNIS) 15th Annual Meeting, found that new stroke imaging technology could decrease delays in care by up to 60 minutes, giving patients a better chance at making a full recovery.
25/07/2018Recent studies show that 40 percent of Americans over the age of 85 have Alzheimer's disease, and that the disease begins 10 to 20 years before people show up at the doctor's office with memory problems.
24/07/2018Harvard University researchers have bioengineered a three-dimensional model of a human left heart ventricle that could be used to study diseases, test drugs and develop patient-specific treatments for heart conditions such as arrhythmia.
23/07/2018Every year, more than 250,000 patients worldwide receive heart valve implants. Children require repeated replacement surgery because their bodies are still growing, the prosthetic heart valves are not. Regenerative heart valves solve this problem. Until now, we have only been able to monitor how these living implants develop in the body after the fact. Computer models now make this predictable.
23/07/2018Scientists from the New York Stem Cell Foundation (NYSCF) Research Institute have developed a new bone engineering technique called Segmental Additive Tissue Engineering (SATE).
23/07/2018A troubled teenager is hospitalized with suicidal thoughts. The patient is diagnosed, medicated, and counseled by a team of experts. The teen is sent home a few days later, and the following week the parent finds the child's bedsheets fashioned into a noose.
18/07/2018Immobility in old age can lead to lower independence and quality of life and increased risk for falls and chronic disease. In the Lifestyle Interventions and Independence for Elders (LIFE) study, a large multicenter clinical trial, researchers found that a regular program of structured physical activity performed in the clinical setting could reduce mobility loss in older adults.
16/07/2018Charité - Universitätsmedizin Berlin and the Berlin Institute of Health (BIH) are pleased to announce that 'The Virtual Brain' neuroinformatics platform has joined the EU's Flagship 'Human Brain Project'. With financial support from the EU's Horizon 2020 research and innovation program, Charité's researchers are now integrating their open-source platform into the 'Human Brain Project'.
16/07/2018The rise of genomics, the shift from considering genes singly to collectively, is adding a new dimension to medical care; biomedical researchers hope to use the information contained in human genomes to make better predictions about individual health, including responses to therapeutic drugs.
13/07/2018Personalized medicine - delivering therapies specially tailored to a patient's unique physiology - has been a goal of researchers and doctors for a long time. New research provides a way of delivering personalized treatments to patients with neurological disease.
13/07/2018Last month alone, 23 percent of Americans took two or more prescription drugs, according to one CDC estimate, and 39 percent over age 65 take five or more, a number that's increased three-fold in the last several decades. And if that isn't surprising enough, try this one: in many cases, doctors have no idea what side effects might arise from adding another drug to a patient's personal pharmacy.
12/07/2018Like with fingerprints, no two people have the same brain anatomy, a study by researchers of the University of Zurich has shown. This uniqueness is the result of a combination of genetic factors and individual life experiences.
12/07/2018Researchers at Linköping University have for the first time been able to use information from computer tomography images to simulate the heart function of an individual patient. Some of the modelling methods they use have been developed in the motor industry.
11/07/2018Researchers at the Centre for Genomic Regulation (CRG) in Barcelona developed a new method to systematically identify genes contributing to heritable cancer risk. Their work, which is published in Nature Communications, is a success story for data sharing and openness in science. Just three researchers identified new cancer genes only using publically available data.
11/07/2018If you want to learn to walk a tightrope, it's a good idea to go for a short run after each practice session. That’s because a recent study in NeuroImage demonstrates that exercise performed immediately after practicing a new motor skill improves its long-term retention.
10/07/2018Is it possible for microscopes to learn a bit about the brain? Even be taught by neuroscientists to reliably recognize parts of brain cells - all on their own? Though it may seem like something straight out of The Jetsons, a neuroscientist and software engineer in the lab of MPFI's Scientific Director is developing new software with the goal of vastly improving the daily life of a microscope user.
10/07/2018A new positron emission tomography (PET) imaging method more fully evaluates the extent of rheumatoid arthritis by targeting translocator protein (TSPO) expression in the synovium (joint lining tissue). The study is featured in the July issue of The Journal of Nuclear Medicine.
09/07/2018Artificial intelligence (AI) holds real potential for improving both the speed and accuracy of medical diagnostics. But before clinicians can harness the power of AI to identify conditions in images such as X-rays, they have to 'teach' the algorithms what to look for.
09/07/2018Designing new molecules for pharmaceuticals is primarily a manual, time-consuming process that's prone to error. But MIT researchers have now taken a step toward fully automating the design process, which could drastically speed things up - and produce better results.
09/07/2018People who are not ill and do not show any symptoms typically do not visit the doctor. And while most people know that preventive medical checkups for cancer, for example, are important, they still avoid them. They tend to be very hesitant because the doctor might detect a serious illness. In the future, a new type of implant could make it easier to go to a screening test.
06/07/2018In the future, companies will be able to offer flexible production close to their customers. A fully automated production line can be housed inside a 20-foot ISO container, which a heavy truck can transport quickly to wherever it is needed. Medical products can be manufactured in close proximity to a hospital, for instance.
06/07/2018People with disabilities such as ALS, spinal injury or Lou Gehrig's disease, often lose use of their legs, arms or hands. Even at advanced stages of the disease, one may still retain movement in their eyes. Some technologies have incorporated eye-tracking to enable disabled persons to interact with a computer to communicate messages to a caregiver.
05/07/2018New methods of studying the evolution of treatment resistance in head and neck cancer are being developed by researchers at the Johns Hopkins Kimmel Cancer Center. The scientists wanted to examine how cancers acquire resistance to treatment over time and whether those changes could be modeled computationally to determine patient-specific timelines of resistance.
05/07/2018A wireless device designed for detection of heart dysfunction in childhood cancer survivors treated with anthracycline chemotherapy was accurate and displayed a low false-negative rate as compared to cardiac magnetic resonance (CMR) imaging.
04/07/2018A total of 200,000 euros has been granted to the spin-off project Theraselect. The Helmholtz Association and Helmholtz Zentrum München will each provide half the funding for the designated spin-off. The project centres around a mass spectrometry imaging method that makes thousands of molecules visible in tissue samples.
04/07/2018While ultrasound is one of the most common medical imaging tools, conventional electronic ultrasound devices tend to be bulky and cannot be used at the same time as some other imaging technologies. A new ultrasound system that uses optical, instead of electronic components, could improve performance while giving doctors significantly more flexibility in how they use ultrasound.
03/07/2018Enabled by a generous gift from the Roy J. Carver Charitable Trust, the BioMaker Lab at the Frederick Seitz Materials Research Lab (MRL) will be the first state-of-the-art interdisciplinary biofabrication hub in the world.
03/07/2018Researchers have developed an accurate diagnostic score that consists of inexpensive blood tests to identify patients who require immediate treatment against the deadly hepatitis B virus – which can lead to liver damage or cancer.
02/07/2018A metal carbide within a hydrogel composite senses, stretches and heals like human skin for use in medicine and robotics.
02/07/2018Scientists from the University of Sheffield's School of Clinical Dentistry, working in close collaboration with Dermtreat A/S from Copenhagen, have developed a unique patch using special polymers which are able to stick to moist surfaces.
29/06/2018Stereotactic neurosurgery is one of the treatment to a variety of movement and neuropsychiatric disorders, s.a. Parkinson's disease, essential tremor and major depression. It involves a technique that can locate targets of surgical interest using an external positioning system, which is widely applied in brain biopsy, tumor ablation, drug delivery, as well as deep brain stimulation ("DBS").
29/06/2018A joint paper by Kazan Federal University and Tatarstan Republican Clinical Hospital appeared in Frontiers in Medicine. As the publication describes, autologous cells of stromal vascular fraction were transplanted to a 36-year-old man with the use of fibrin matrix. The patient, whose injury had been caused by a fall, then has been under supervision for 2 years.
27/06/2018An algorithm to monitor the joints of patients with arthritis, which could change the way that the severity of the condition is assessed, has been developed by a team of engineers, physicians and radiologists led by the University of Cambridge.
27/06/2018The genetic causes of a group of related infant cancers have been discovered by scientists at the Wellcome Sanger Institute, the University of Wuerzburg and their collaborators. Whole genome sequencing of tumours revealed mutations which are targetable by existing drugs used to treat lung cancer and melanoma.
26/06/2018Scientists may now be able to predict whether carrying a specific genetic variant increases a person's risk for disease using gene editing and stem cell technologies, according to new research in the American Heart Association's journal Circulation.
25/06/2018A biomimetic nanosystem can deliver therapeutic proteins to selectively target cancerous tumors, according to a team of Penn State researchers. Using a protein toxin called gelonin from a plant found in the Himalayan mountains, the researchers caged the proteins in self-assembled metal-organic framework (MOF) nanoparticles to protect them from the body's immune system.
22/06/2018People with severe mental illness are more than twice as likely to have Type 2 diabetes, with even higher risks among patients who are African American or Hispanic, according to a new study led by UCSF.
22/06/2018New structural details emerge about one of the body's biggest protein assemblages, the nuclear pore complex.
22/06/2018A drop of blood provides a lot of valuable information. However, it takes several hours to analyze the blood of a patient and make a diagnosis. This takes away a lot of time that's crucial for treatment. A new method intends to considerably speed up this process by testing the cells in the blood in terms of their deformability and immune response.
21/06/2018New study from University Hospitals Connor Integrative Health Network published in the Journal of Music Therapy.
21/06/2018Researchers have developed an artificial tissue in which human blood stem cells remain functional for a prolonged period of time. Scientists from the University of Basel, University Hospital Basel, and ETH Zurich have reported their findings in the scientific journal PNAS.
20/06/2018Around two to six per cent of all people with obesity develop obesity already in early childhood; it's in their genetic cards. Obesity-causal mutations in one of their "appetite genes" gives them a strong genetic predisposition for developing obesity, also called monogenic obesity. Their experience of hunger is overruling and their feeling of satiety limited.
20/06/2018The study found poor sleep quality was associated with nighttime snacking and a high likelihood of craving junk food. The study also found that junk food cravings were associated with increased risk of obesity, diabetes and other health problems.
19/06/2018Penn study reveals that microRNAs predict differences in cognitive impairment in memory and attention after sleep deprivation.
19/06/2018If immunoglobulin E (IgE) antibodies are directed against harmless antigens such as pollen, the result can be an allergic reaction. However the original purpose of these IgE antibodies is to repel harmful exogenous substances rather than to trigger allergies.
18/06/2018Serotonin keeps mice hanging on if they are sure of getting rewards, but not sure when.
18/06/2018Researchers at the Cells-in-Motion Cluster of Excellence have decoded a mechanism found at the beginning of almost every inflammatory response. Their study provides a new approach to develop novel treatment options for many inflammatory disorders with many fewer side effects compared to current drugs.
15/06/2018The so called "diabetic retinopathy" and the "diabetic macular edema" are two of the most frequent ocular diseases in patients with diabetes, and both feature pathologic changes of blood vessel functions in the retina. Experimental data and measurements in patients suggest that these changes in blood vessel functions may originate from a lack of vasoinhibin hormones in the retina.
15/06/2018The first antibiotic against tuberculosis that has been developed in Germany is now ready for clinical testing. BTZ043, as the newly developed drug substance is called, is also effective against multidrug-resistant pathogens which are increasingly challenging successful treatment worldwide.
14/06/2018An unexpectedtwo-step mechanism occurs when cells copy DNA.
13/06/2018A new Collaborative Research Center will start in July with a total funding of nearly 14 million euros, headed by the German Institute for Experimental Biomedicine in Würzburg. The aim is to decode the complex and insufficiently understood functions of platelets, the so-called thrombocytes.
13/06/2018The heart of a neonatal mouse is capable of self-repair after tissue damage. However, this ability disappears during the first week of life. Researchers at the University of Helsinki investigate the molecular mechanisms underlying myocardial regenerative ability.
12/06/2018Researchers at the Paul-Ehrlich-Institut have reproduced measles virus transmission in an animal model. They were able to show that an efficient interaction with two cellular receptors plays a decisive role in the efficient transmission of the virus.
12/06/2018For over a century, we have known that high altitude reduces the amount of blood the heart pumps around the body with each beat. New research published in The Journal of Physiology has unearthed why this is the case and the findings will be important for people who live, travel and exercise at high altitudes.
11/06/2018Research from the University of Illinois at Chicago has found that some of the genes affected by alcohol and inflammation are also implicated in processes that clear amyloid beta - the protein that forms globs of plaques in the brain and which contributes to neuronal damage and the cognitive impairment associated with Alzheimer's disease.
11/06/2018Women are more prone to the development of autoimmune diseases. The female hormone estrogen is likely to affect the immune system. A team of scientists from Turku Center for Biotechnology and University of Georgia reported new findings related to the involvement of estrogen hormone receptor in autoimmune diseases.
08/06/2018Developing new medicines to treat pulmonary fibrosis, one of the most common and serious forms of lung disease, is not easy. One reason: it's difficult to mimic how the disease damages and scars lung tissue over time, often forcing scientists to employ a hodgepodge of time-consuming and costly techniques to assess the effectiveness of potential treatments.
08/06/2018A common in optometrists' offices may hold the key to faster diagnosis of schizophrenia, predicting relapse and symptom severity and assessing treatment effectiveness, a Rutgers University study finds.
07/06/2018A new study, affiliated with UNIST has recently presented a novel statistical algorithm, capable of identifying potential disease genes in a more accurate and cost-effective way. This algorithm has also been considered as a new promising approach for the identification of candidate disease genes, as it works effectively with less genomic data and takes only a minute or two to get results.
07/06/2018The researchers investigated faulty versions of a gene called titin which are carried by one in 100 people or 600,000 people in the UK. Titin is crucial for maintaining the elasticity of the heart muscle, and faulty versions are linked to a type of heart failure called dilated cardiomyopathy.
06/06/2018An operation that targets the nerves connected to the kidney has been found to significantly reduce blood pressure in patients with hypertension, according to the results of a clinical trial led in the UK by Queen Mary University of London and Barts Health NHS Trust, and supported by the National Institute for Health Research (NIHR).
06/06/2018A healthy, low-fat diet and undisturbed sleep play an important role in remaining fit and full of energy during the day. Sleep quantity, on the other hand, is of less importance. This is the finding of a recently published study in the journal Health Behavior & Policy Review, which was conducted at Jacobs University Bremen.
05/06/2018When cells become stressed, they activate specific response patterns. Würzburg researchers have identified new details of these responses, which can help to get a better understanding of neurodegenerative diseases.
05/06/2018Antimicrobial resistance is a major medical problem worldwide, impacting both human health and economic well-being. A new strategy for fighting bacteria has now been reported in the latest online issue of Nature by a research group headed by Prof. Dikic at the Goethe University Frankfurt. The scientists revealed the molecular action mechanism of a Legionella toxin and developed a first inhibitor.
04/06/2018Aging is associated with an increase in frailty and age related-diseases. A calorie-restricted diet is known to alleviate these age-related conditions. Researchers from the ERIBA in Groningen, Netherlands, and the FLI in Jena, Germany, now demonstrate in a mouse model that the C/EBPß-LIP gene regulator is involved in the aging process.
04/06/2018Urine is an everyday liquid which most people pay little attention to and regard as rather unpleasant. It’s quite the opposite for a group of clinical researchers from Kiel University, the University Medical Center Schleswig-Holstein (UKSH) and the Lithuanian University of Health Sciences in Kaunas, who are convinced of the diagnostic potential of this yellowish liquid.
01/06/2018A study of more than 7,000 low-income, urban mothers enrolled in the Boston Birth Cohort found that fewer than 5 percent of them started folic acid supplementation and used it almost daily before pregnancy, a widely recommended public health measure designed to prevent potentially crippling birth defects.
01/06/2018Research by physician-scientists at the University of Colorado Anschutz Medical Campus offers hope for improved quality of life for people who rely on intravenous nutrition due to intestinal damage.
31/05/2018A lot can happen at 160 degrees Fahrenheit: Eggs fry, salmonella bacteria dies, and human skin will suffer third-degree burns.
31/05/2018Considering the size of red blood cells, a new model for blood flow sheds light on why blood sometimes prefers some vessels over others.
30/05/2018Penn Medicine research explores adolescent and young adult social media use and drinking patterns.
30/05/2018Microgravity conditions affect DNA methylation of muscle cells, slowing their differentiation.
29/05/2018Early damage could open door to dementia, lead author says.
28/05/2018Invasion has a long tradition and is being accelerated by globalisation, trade and tourism.
25/05/2018A group of researchers from Graduate School of Pharmaceutical Sciences at The University of Tokyo and Institute of Traditional Chinese Medicine and Natural Products at Jinan University, identified the biosynthetic gene cluster for the furanosteroid demethoxyviridin, and deciphered its biosynthetic pathway.
25/05/2018Macrophages are white blood cells involved in a variety of biological functions, from destroying infectious pathogens to repairing damaged tissue. To carry out their different roles, macrophages must first be activated and transformed into different subtypes. However, the mechanisms that lead to macrophage activation are not fully understood.
24/05/2018The transition to modernity – largely driven by the Industrial Revolution – provided us with easier access to food and clean water, with antibiotics, vaccines, and modern medicine. Yet modernity did not just bring fewer infectious diseases and longer life: it also created an environment radically different from the one we evolved in.
24/05/2018Fibrils of the protein alpha-synuclein, that plays a role in Parkinson's disease, form a stiffer and stronger network in water, when temperature is increased. Researchers of the University of Twente show that this has to do with the water-repellent part of the fibres coming to the surface and interacting.
22/05/2018This unusual ally can be extremely valuable in the fight against inflammation in the body: CO (carbon monoxide). As a therapeutic gas, it also promises relief for inflammatory gastrointestinal diseases. Having said that, it is difficult to transport the active ingredient to the exact desired location.
22/05/2018Stem cells in the brain can divide and mature into neurons participating in various brain functions, including memory. In a paper published in the journal Cell Stem Cell, scientists at Helmholtz Zentrum München and Ludwig-Maximilians-Universität München have shown how this works. They found that ion channels play a key role in mediating force signals to the neural stem cells to activate them.
22/05/2018The way you walk can reveal current and future health problems. New research from Halmstad University suggests the use of wearable sensors for analysing your movement. This can potentially result in early detection of for example Parkinson's disease, dementia, multiple sclerosis and other neuro-physiological disorders.
21/05/2018Researchers at the University of Southampton have developed a new computational way of analysing X-ray images of lungs, which could herald a breakthrough in the diagnosis and assessment of Chronic Obstructive Pulmonary Disease (COPD) and other lung diseases.
21/05/2018Researchers at Tokai, Osaka, Tohoku and Fukuoka Universities report in the journal Communications Chemistry on the synthesis of insulin based on the self-assembly of polypeptide chains at about 40% efficiency.
18/05/2018Protein clumping may contribute to heart failure development and could be used as a diagnostic tool for testing therapies or disease progression.
18/05/2018A little-explored group of immune cells plays an important role in the regulation of intestinal bacteria. Changing metabolic states of the microbes have an effect on defense cells at different stages of alert or rest, as researchers from the Department of Biomedicine at the University and University Hospital of Basel report in the journal Mucosal Immunology.
17/05/2018A neuron model of Parkinson's disease and Lewy body dementias shows defects that could suggest treatments to halt or reverse cognitive impairments before the neurons die.
17/05/2018One gram of fish oil a day could help reduce the pain of patients with osteoarthritis, a new study in Rheumatology reports.
08/05/2018Multidrug-resistant organisms that are treated with a dosage that exceeds the regular dose a hundred times and at temperatures of over 40 degrees Celsius – the human organism is unable to handle it. Yet if the diseased organ is treated outside of the body, extreme conditions are an option. For the first time, physicians have succeeded in treating a severe case of pneumonia by using the OCS.
02/05/2018When human movements are no longer as smooth as they should be – due to misalignments or as the result of an injury for example – biomechanical measuring systems spring into action. Thanks to different types of sensors and optical technologies, physicians, therapists, and sports scientists embark on a search for possible causes and corrective options.
23/04/2018A bypass is a complicated structure. It is either made of synthetic materials that can cause blood clots and infections or created by using the patient’s veins. However, the latter often does not yield adequate material. A newly developed bioreactor could solve this problem in the future. It is designed to tissue engineer vascular grafts by using the body’s own material.
09/04/2018When a skin lesion is suspected to exhibit malignant changes, it is usually promptly removed. However, not all cases require an excision of the affected tissue. The startup company Magnosco has developed a procedure that uses a laser to support the diagnosis and early detection of malignant melanoma.
22/03/2018Virtual reality and medicine are increasingly mentioned in the same context. In addition to the development of applications that support the treatment of patients suffering from chronic pain and anxiety, this technology also benefits medical staff. Two months ago, the Ulm University Hospital has opened the VR Lab, where medical students can train and learn with the help of 3D organs.
08/03/2018Automation makes work life easier in many ways but is it also a solution for analyzing medical images? Is a computer actually reliable enough to assist in the medical decision making process? Researchers in Landshut examine how machine learning algorithms can work more reliably and support radiologists.
01/03/2018Conventional cancer treatment selection typically depends on the location of the tumor. However, this approach ignores the distinct gene mutations in the tumor of the individual patient. New cancer research approaches increasingly emphasize the concept of personalized therapy.
01/03/2018Personalized medicine does not follow a "one-size-fits-all" treatment approach but emphasizes a "tailor-made" paradigm, meaning a treatment is customized to each individual person's case. For patients, this increases the chances of treatment success and means fewer side effects. While the approach originates in the field of oncology, it is now also increasingly applied to other disease patterns.
01/03/2018Everyone is different. This statement also applies to our health. Cancer, in particular, can look and progress differently depending on the individual person. That’s why every patient ideally also needs a customized treatment that is tailored to their individual needs. But how feasible is this idea?
22/02/2018Here on Earth, all experiments are bound by gravitation. Yet, freed from gravity's grip, tumor cells, for example, behave in an entirely different way. As part of the "Thyroid Cancer Cells in Space" project by the University of Magdeburg, smartphone-sized containers carrying poorly differentiated thyroid cancer cells are sent into space.
08/02/2018When body tissue is reconnected during a tumor operation in the gastrointestinal tract, surgeons need information about the current state of these so-called anastomoses. The new, non-invasive hyperspectral imaging technology now makes it possible to measure the crucial parameters during surgery and thereby increase surgical precision.
22/01/2018Research does not always occur in laboratory settings. As part of citizen science, citizens collect data and make it available for research projects. Now, this approach is also adopted in medicine by way of patient science: in a new project, patients take part in cystic fibrosis research. The goal is to improve the lives of those who are affected by this chronic disease.
08/01/2018Few patients with heart failure are fortunate enough to receive a donor's heart. Ventricular assist devices (or heart pumps) have been around for several years and are designed to buy time as patients wait for a transplant. Unfortunately, the body doesn't always tolerate these devices.
04/01/2018While it is commonplace for operating room staff to work together as a team, the collaboration of operating room systems does not always work so well – many devices are still separated from one another, causing the OR processes to be prone to mistakes. The same applies to surgical navigation technologies that represent the interface between imaging, the surgeon and therapeutic devices.
20/12/2017Sixty percent of newborns are affected by jaundice during their first days of life. In most cases, the condition is harmless. The ailment is more pronounced in premature babies, whose treatment involves irradiation with blue light in a special incubator – naked and alone.
22/11/2017Human trafficking is a global crime that often preys on underage persons and forces them into prostitution and forced labor. In most cases, people are smuggled across borders with fake passports. Scientists at the Fraunhofer IBMT have now developed a non-invasive, handheld smartphone-compatible scanner that uses ultrasound to determine whether a person has reached full legal age.
08/11/2017Major surgeries in the abdominal region often result in kidney injury in patients. Meanwhile, the clinical manifestations don't present until one or two days after the procedure. This causes physicians to lose valuable time to treat patients. The University Hospital Regensburg has researched a new concept for the treatment of kidney injuries for several years.
23/10/2017According to the WHO, 300 million people throughout the world are affected by lymphedema. This condition occurs when fluid that flows between cells is no longer transported back into the blood circulation and accumulates in the skin. Triggers can be surgeries, injuries or genetic defects for example. A new microscopy technique could now also indicate the causes.
09/10/2017Whole-body electromyostimulation (WB-EMS) promises time-efficient muscle strength training that has positive effects after just a few sessions per week. Its objective is a fast increase in muscle mass and reduction of body fat. Can WB-EMS training replace conventional strength and endurance training? And can it help to prevent diseases or pain?
02/10/2017If you are interested in laboratory medicine and come to the MEDICA 2017, you will quickly notice that Exhibition Halls 1 and 2 were demolished. A new state-of-the art hall is meant to take their place. Until then, exhibitors from the field of laboratory medicine will be showcased at their temporary new location in the lightweight hall structures 3a and 18 on the fairgrounds.
22/09/2017Many people all over the world suffer from myopia, also known as nearsightedness. A severe elongation of the eyeball is the cause behind it. If it continues to progress, it ultimately leads to complete loss of vision. Now an innovative medical device intends to stop this progression in the future.
01/09/2017There are many causes of myocarditis or inflammation of the heart muscle. Oftentimes, the culprits are viruses or bacteria and sometimes even an acute heart attack. Regardless of the cause, it creates a challenge for cardiologists: a diagnosis tends to be only nonspecific without a biopsy. A cardiac MRI and molecular imaging promise to provide assistance.
22/08/2017Physics has always supported medical science, especially when it comes to practical implementation. Now physicists and health professionals join in collaborative research at an interdisciplinary Center in Erlangen and incorporate fundamental principles of theoretical physics in their studies of diseases.
08/08/2017For centuries, scientific research has succeeded by chronicling experiments with pinpoint accuracy. Yet despite all the progress in the actual laboratory, recording is often still done manually, in notebooks, logs or computer systems for instance. In the future, a gesture recognition system could perform this task for scientists.
01/08/2017An increasing percentage of the world population suffers from chronic inflammatory disorders of the respiratory system. Acute attacks often lead to a worsening of the disease and considerably reduce the patient’s lung volume. Nine institutes of a research alliance under the Leibniz Institute umbrella are working on technologies designed to predict and thus prevent exacerbations.
01/08/2017Many therapeutic drugs are very powerful, but they are also very toxic at the same time. Thus, they have to be measured regularly, again and again, so that an adjustment of the individual drug dosage can be made. Until now, the "normal" way was to take the blood sample, send it to a central laboratory and get the results after some days. A new point-of-care test can measure it in 15 minutes.
24/07/2017A new analysis method that uses fetal DNA extracted from the mother’s blood is designed to non-invasively reach a prenatal diagnosis of genetic disorders in a child. A task force of the Hahn Schickard Society for Applied Research is an active part of the "ANGELab" project and co-developed this diagnostic procedure.
10/07/2017Radiation therapies are an essential component of today’s oncology because they enable the treatment of localized tumors. Yet they have one major drawback: radiation damages not just tumor cells but also healthy tissue. One solution to solve this problem could be proton minibeam therapy, which uses finely focused beams.
22/06/2017The doctor's profession is exhausting and involves many different activities. For a long time, there have been discussions about how doctors can be supported by other specialists. One solution: help from so-called physician assistants.
08/06/2017After earthquakes or other types of disasters, infrastructures are often damaged and local hospitals destroyed. A modular hospital, developed under the direction of the European Commission’s Humanitarian Aid and Civil Protection Department is designed to be ready for these types of disaster situations and support the emergency response.
01/06/2017After a stroke or as a result of aging, there are many situations when people are impaired in their walking ability and rely on a personal assistant or auxiliary aids and services. The XoSoft Project offers a solution: a soft exoskeleton that can be worn like a pair of leggings and stiffens or softens, depending on the situation.
22/05/2017For many years, cochlear implants have restored a sense of hearing in people with certain types of hearing loss. For surgeons, the implantation requires a precise attention to detail under the microscope. The results for the patients improve significantly with a more precise placement of the electrode array. The use of a surgical robot can increase the accuracy of the procedure.
08/05/2017How can emergency room associates continue to educate themselves in a fast manner and without bureaucratic hurdles? The A.L.I.N.A Project, which gives associates new tools with special assistance services and learning environments, delivers the solution. We spoke with Prof. Sabine Blaschke at the University Hospital Göttingen about these tools and how they work.
02/05/2017India is a land of contradictions. On the one hand, it has densely populated cities with state of the art technology. On the other hand, two-thirds of the population still live under challenging hygienic and financial conditions in the rural areas. Despite these conditions or perhaps because of them, more and more medical technology companies from all over the world are interested in this market.
02/05/2017When it comes to the production and development of tech products, many people immediately think of Germany, Japan, the U.S. or Taiwan. What’s often unknown is that an emerging market like India also offers great potential. After all, the country has a large number of experts and just as much technical knowledge at its disposal.
24/04/2017Liver cancer is the fifth most common malignant tumor in the world. The tumor can be removed through surgery or by utilizing thermal ablation techniques. If a treatment with conservative methods is no longer possible, there is an alternative: irreversible electroporation (IRE). The effectiveness of this method was now confirmed by a clinical study.
10/04/2017People with hip osteoarthritis often suffer from severe pain and only an endoprosthesis implantation can provide relief. This involves a major intervention and long-term rehabilitation because the implant requires the removal of a section of the thigh bone. The "MioHIP" research project looks for an elastic alternative.
03/04/2017Instant treatment is absolute vital for patients developing sepsis. Providing a specific therapy early on is key. To manage this the pathogenic organisms need to be identified accurately. But a fungal sepsis can still be a hard nut to crack.
03/04/2017Many aspects are uniformly regulated in Europe, however, hospital hygiene and MRSA prevention, for example, are not. The Netherlands plays a pioneering role in the fight against hospital-acquired infections. The country is an often-cited role model. But can other countries simply adopt the same system? And what makes it so different? MEDICA asked expert Prof. Alexander W. Friedrich.
03/04/2017The laboratory is one of the most important and pivotal bastions in patient care. In the laboratory, acute, chronic and genetic diseases are diagnosed, the progression of diseases such as diabetes is regularly checked or specialists look for biomarkers to adapt cancer therapies.
01/03/2017In the "KDI – Clinical Data Intelligence Project", researchers are trying to consolidate various types of data to make them useable and useful to both medical professionals and scientists. This is a tremendous undertaking, considering the data volumes from different sources. In this conversation with MEDICA, Dr. Martin Sedlmayr explains the project setup.
22/02/2017Surgeons need a great sense of touch. They first have to acquire this skill in simulation training before they can perform surgery on actual patients. Having said that, simulators are not just meant to teach the right movements; ideally, they should also provide a true-to-life experience of the surgical field – as is the case in RealSpine surgical training.
08/02/2017Listening to your favorite music for at least 90 minutes a day and treating your tinnitus with it? Almost sounds too good to be true. Yet more and more German statutory health insurance providers pay for this treatment. We wanted to know more about it and spoke with Jörg Land, the CEO of Sonormed GmbH, about Tinnitracks.
01/02/2017Using stents to treat glaucoma is not a new procedure but they have not been implanted into patients on a regular basis until only recently. But this is about to change, which is why MEDICA.de asked what these glaucoma mini-stents are able to do and who may be a good candidate for them. Professor Norbert Pfeiffer answered our questions.
01/02/2017Achromatopsia is a rare hereditary visual disorder. Along with total color blindness, patients most notably suffer from reduced visual acuity and increased sensitivity to light and glare.
02/01/2017Treatments for children need to be different from treatment for adults – this also applies in oncology. Having said that, children do not just need new and different treatment concepts that still necessitate research. They also require the support from their families, who need to be nearby during treatment.
21/12/2016Within the scope of the VIRUSCAN project that is funded by the Horizon 2020 Research and Innovation Program of the European Union, Dr. Charlotte Uetrecht from Hamburg/Germany investigates individual viruses to be able to later identify them on a nanospring structure. MEDICA.de wanted to know: how does this work?
08/12/2016Watching millions of neurons in the brain interacting with each other – for a long time this was possible only to a limited extent. The current techniques can visualize only superficial layers or the imaging they use is too slow. But now, Prof Daniel Razansky and his team have found a new method to visualize the brain activity – by using optoacoustics.
22/11/2016It happens about 1,800 times per year: after a sporting or traffic-related accident, a person’s spinal cord is injured to where nerve tracts are severed and he/she becomes paralyzed. Researchers now want to develop software that measures the brain signals of paralyzed patients and sends out electrical impulses via a system to stimulate muscles, causing them to move again.
02/11/2016Call systems: every hospital patient is familiar with them, but hardly anyone gives any thought to how they work. And yet they fulfill an important function because in an emergency, they "call" for help. Just think what might happen if they didn’t work. That is why they are subject to stringent safety regulations. We spoke with D.Eng. Matthias Rychetsky, who is familiar with call systems.
04/10/2016So far, avatars could only be found in computer games. But if researchers of the EU-wide www.myhealthavatar.eu project have their way, this could soon change.
04/10/2016Chronic inflammatory bowel diseases like Crohn’s disease and ulcerative colitis increasingly develop at a younger age and affect patients for life. Regular check-ups need to occur every two to three months. Now, a specially designed app intends to provide relief.
08/09/2016For many patients, the start of hemodialysis marks the lifelong dependency on needing their blood purified. But before they can actually begin treatments, a blood vessel in the patient's arm needs to be enlarged to where it can move enough blood and withstand being connected to the dialysis machine several times per week.
01/09/2016Patients take center stage during surgery. Their treatment should be as gentle and effective as possible, which is why there is a trend towards minimally invasive surgery (MIS). But minimal procedures require better supporting technologies. The hybrid operating room combines surgery and imaging systems and increasingly replaces conventional open surgery approaches with MIS.
22/08/2016A beautiful field of flowers, a trip to the beach or a visit to the zoo. Children can experience all of these at the Clinical Center Dortmund in a 270- degree projection on the wall. The Center created a space that is designed to help its little patients overcome their fear of MRI scans.
08/08/2016What happens when stem cells differentiate? What molecular characteristics do they have? Questions that can now be easier answered with the help of a new open-source software. We spoke with Prof. Fabian Theis at the Helmholtz Center Munich, who participated in the software development.
22/07/2016Millions of people all over the world suffer from partial blindness – caused by glaucoma, a stroke or traumatic brain injury. For years, the loss of vision was deemed irreversible. But now a new treatment makes it possible to improve eyesight and vision.
08/06/2016Just a few minutes can make the difference between life and death when a person loses consciousness or goes into sudden cardiac arrest. Unfortunately, emergency medical services cannot always be on location as fast as needed. To ensure immediate life-sustaining measures, the "mobile rescue" app was developed, which alerts emergency medical responders in the immediate vicinity of an emergency.
01/06/2016Some hospitals have long banned the status symbol of physicians – the white coat. Research has shown that especially the sleeves were contaminated with various types of bacteria. But it’s not just lab coats that can spread germs in healthcare settings. This field uses a variety of different textiles. Wouldn’t it, therefore, make sense to apply antimicrobial finishes?
22/05/2016The treatment for diabetes is very time-consuming for patients: they need to regularly monitor blood sugar levels, take medication and inject insulin. Poor self-management may result in a dangerous lapse in blood glucose levels. Yet external factors can also contribute to diabetes being out of control. An artificial pancreas system could offer relief.
02/05/2016Heart failure or cardiac insufficiency presents an extra strain on patients because it severally limits everyday performance and deprives them of energy. Due to their intense need for movement, children are particularly strongly affected. However, the disease is frequently not detected until the physical performance is already declining. An early diagnosis could prevent this.
22/04/2016How can you print ceramics, what purpose do they have and how benefits medical technology? Answers provides Dr. Tassilo Moritz from Fraunhofer Institute for Ceramic Technologies and Systems IKTS.
22/03/2016Medical apps like diabetes or high blood pressure diaries are becoming increasingly popular with smartphone users. There are many available choices out there but they are not always clear. Added to this is the question of how the data collected by the apps can be sensibly incorporated into treatment.
08/03/2016Pancreatic cancer is one of the deadliest forms of cancer because it is difficult to diagnose and only presents with symptoms in the later stages. In the future, a laboratory test developed at the Greifswald University Medicine could make an early detection of this type of cancer and consequently a faster and better treatment possible.
22/02/2016Easy solutions that deliver results quickly are a great asset in medicine: patients receive their diagnosis faster and physicians have more time to treat them. Such tools also work without sophisticated resources and trained personal. A device currently developed in a project funded by the European Commission could bring all of this to point-of-care-testing for infectious diseases.
09/02/2016Many people suffer from atherosclerosis, especially in developed countries. The buildup of fatty deposits inside the arterial blood vessels leads to strokes and heart attacks. Now, a new method is designed to get to the root of the problem, and with the help of nanoparticles inject new turbo replacement cells into the blood vessels which are intended to exert their curative effect.
22/01/2016It may fits, but somewhere it still tweaks. Although a suit off the rack serves its purpose, it is still far from being an ideal solution. With a custom made heart it is different. It is similar with implants. Often patients complain about the fact that those implants feel strange. 3D printing is on the best way to change this. Here, the implants are adapted to the carrier.
08/01/2016There are various artificial heart valves available for children, but they have one essential drawback: they need to be replaced because the children are still growing. The artificial valve, on the other hand, remains the same size – and subsequently becomes too small. This is why an artificial heart valve that grows over time would be ideal.
04/01/2016Most Europeans think it was a long time ago, but the residents of West Africa clearly feel the consequences of the Ebola epidemic that broke out in December 2013 and still continues today. So far, approximately 11,300 people have died as a result of the outbreak; more than 28,000 contracted the disease.
01/12/2015If you could stimulate brain cells to grow in a specific direction, you would probably be able to achieve a significant improvement in the health of patients suffering from Parkinson’s disease. This is why the MAGNEURON project focuses on this approach. The EU is funding the project with approximately 3.5 million Euros.
02/11/2015Minimally invasive surgeries are gentler on the patient but have one distinct disadvantage for the surgeon: he is not able to interact directly with the operating field. Sometimes he misses impressions that are very important to the success of the intervention. The MiroSurge robot for surgical applications which transmits feedback to the surgeon can help.
01/10/2015Semiconductor nanoparticles for biomedical applications have been researched for some time now. Not only are they millionths of a millimeter in size, they also offer great potential for cancer diagnostics and therapy, so-called theranostics. They enter cells, are activated by ultrasonic radiation and destroy the cells using the generated vibration.
01/10/2015It is a portmanteau, a mixture of two words. This way it saves us time and trouble while speaking because the human speech apparatus is lazy. And it describes a mixture of procedures: the combination of two procedures that would normally be separate in medicine. We are talking about theranostics.
01/09/2015They can be seen everywhere: at the wrists, in the ear, clipped to the belt. Wearables are small technical assistants who are built to collect and partially also to analyze data. Some of them collect measurable health data, others "only" count their user’s steps or measure the surrounding UV radiation. The fact is, however, that wearables are en vogue and are used for many different cases.
03/08/2015Malignant tumors can be fought with X-rays – usually with radiation therapy from outside the body. Nuclear medicine physicians can also accomplish this inside the body with radioactive materials, called radiopharmaceuticals. They also offer big benefits for clinical diagnostics as long as a specific target can be assigned to them.
01/07/2015When measuring myocardial activity, it is important for the skin to always stay moist under the electrodes of the ECG. Only then can data be consistently transferred. Athletes have an easier time with this: they are used to sweating. This is a lot harder for older patients.
01/06/2015When cancer is diagnosed, the terms tumor markers or biomarkers keep popping up. They describe characteristics that are not found in healthy persons. The classic tumor markers can be easily detected in blood samples or other body fluids. Other analysis methods require more effort. Yet they all share one thing in common: biomarkers indicate a potential tumor.
01/06/2015A tumor is as unique as the person who is affected by it. For a long time, it was assumed this would make treatment more difficult since cancer drugs are not able to be one hundred percent effective in targeting the affected cells. In this interview with MEDICA.de, Professor Ugur Sahin explains why it is precisely these individual mutations that make him hopeful for a new type of therapy.
04/05/2015Since the end of April 2015, the long-awaited evaluation report on the skin cancer screening programs offered by German health insurance providers is now finally available. We spoke with Dr. Ralph von Kiedrowski, Board Member of the German Dermatologist Association (German: Berufsverband Deutscher Dermatologen) on what the screening can accomplish and his take on the G-BA report.
02/03/2015How should a hospital best respond to an emergency and which types of crises should it be prepared for? We spoke with Professor Ronald Glasberg at the SRH Hochschule Berlin on this subject.
02/02/2015Only projects with a solid foundation are successful in the long run. This is also true for science. Biobanks are the most important component of this foundation when it comes to fundamental biomedical research: Only high quality tissue samples that are stored there make conclusive research possible - for example in search of the causes of tumorigenesis.
05/01/2015T-cells are the guardians of our immune system. When they show changes, it can lead to severe inflammatory responses in the body. It is believed that the T-cells in persons who are affected by inflammatory bowel disease don’t work properly. Two proteins that can be found on activated T-cells and that interact with each other are now being analyzed.
01/12/2014How does a physician handle a patient, who wants to die and what rights do I actually have as a patient? Legal practitioners do not automatically answer these and other questions. We talked about this subject with MD-PhD Ralf Jox from the Institute of Ethics, History and Theory of Medicine at the Ludwig Maximilians University of Munich, Germany.
03/11/2014As an imaging procedure, magnetic resonance tomography has become essential in clinical practice, since it can easily make organs and tissue visible. However, until now abnormal cancer cells or small centers of inflammation remained almost invisible. Now cell biologists from Berlin, Germany, have succeeded in fixing this problem with xenon magnetic resonance imaging.
03/11/2014The treatment of chronic wounds is extremely problematic. Chronic wounds can take months or years to heal and some even never heal resulting in over 100.000 amputations taking place annually in the US alone. A new technology from Iceland, that is based on fish skin and is already used clinically, allows for improved healing of chronic and burn wounds.
01/10/2014On November 10, 2014, astronaut Alexander Gerst will return to Earth from the International Space Station (ISS). He is not just anxiously expected by his family, but also by Dr. Anna-Maria Liphardt from the Institute of Biomechanics and Orthopedics at the German Sport University Cologne
01/09/2014The public only notices diseases when celebrities become patients: in the spring of 2014, Formula One driver Michael Schumacher fell into a coma for several months as the result of a head injury caused by a skiing accident. These types of accidents show how delicate the brain responds to injuries. Brain stimulation could possibly support the rehabilitation of vegetative patients.
01/09/2014When very young children already need to be in the operating room, it’s not just the parents that are concerned. This type of situation is a special challenge for the entire operating team, because children are always very special patients - especially since they are not just simply small grown-ups!
01/07/2014In patients with Parkinson's, neural cells in the brain die off that produce the neurotransmitter dopamine. Certain physical symptoms that can indicate the disease follow years later. But a reliable diagnosis can only be made through examination of the brain after the patient's death, and not during his lifetime.
01/07/2014The not so popular “love handles“ could revolutionize medicine in the near future. In cooperation with the University of Rostock (Professor Hermann Seitz), the human med AG Company currently seeks to develop a device that is able to gently remove adipose tissue during surgery and subsequently isolate stem cells.
02/06/2014When are sports healthy, how often should you engage in sports and what effect do sports have on the body – over the past few decades, there were always different answers to these questions. Many studies that were conducted in the past however confirm the assumption that sports and exercise always support health, even if someone is already sick.
02/05/2014Staying active and mobile when you are old – who doesn’t want that? People suffering from dementia can often only dream about that. The fear of not finding your way back home or not getting any help in an emergency severally restricts many affected people in the way they live their lives. Yet there are many people, who could still independently participate in life despite mild dementia.
04/03/2014Continuing education is an integral part of the medical profession, because research continuously delivers new findings that sooner or later make their way into patient treatments. How does an event need to be organized to provide the highest level of benefit for the participants? MEDICA.de spoke with Eva Ningel, Managing Director for beta seminare bonn berlin GmbH (bsbb).
03/02/2014Radiologists usually do their work after oncologists when it comes to cancer treatment. Yet modern radiology also provides treatments at this point. MEDICA.de spoke with Professor Stefan Schönberg, Director of the Institute of Clinical Radiology and Nuclear Medicine at the University Medical Center Mannheim, Germany, about the use of a new computer tomograph and its benefits for patients.
06/01/2014Whether a surgical suture is better applied manually or with a surgical stapler can be determined through trial and error. Determining which method guarantees patient safety best should also not just be based on a surgeon’s experience. Controlled studies are the method of choice to assess both well-proven and new techniques in the operating room.
06/01/2014Even medical risk products are not always tested as thoroughly as would be necessary – be it because of criminal energy, lack of know-how or financial reasons. A revision of clinical trial procedures could not only fix loop holes and methodological flaws. Products and methods could also be brought into general medical care more quickly under new rules.