Articles -- MEDICA - World Forum for Medicine

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Clear link between fitness in middle age and risk of dementia


Women who have a high cardiovascular fitness in middle age have a risk of developing dementia when older that is almost 90 percent lower than among women in average physical condition, according to a study published in the journal "Neurology".
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Image: Optical readouts of HL-1 cardiomyocytes in response to chemical uncoupling by CCCP in blue and yellow; Copyright: Irene Georgakoudi, Tufts University

Researchers develop optical tools to detect metabolic changes linked to disease


Metabolic changes in cells can occur at the earliest stages of disease. In most cases, knowledge of those signals is limited, since we usually detect disease only after it has done significant damage.
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New insights into why patients have a higher risk of heart attack in the morning


Cardiovascular disease patients have lower levels of an important family of protective molecules in their blood in the morning, which could be increasing their risk of blood clots and heart attacks at those times, according to early research led by Queen Mary University of London.
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Prediabetes patients at heightened risk for cardiovascular and chronic kidney diseases


Researchers at the Emory Rollins School of Public Health and U.S. Centers for Disease Control and Prevention have found that high proportions of patients with prediabetes are at substantial risk for cardiovascular disease and chronic kidney disease. Their findings are published in "The Lancet Diabetes & Endocrinology".
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Signals of the heart: TU Darmstadt works on algorithms to detect atrial fibrillation


There are currently an estimated 1.8 million people in Germany who have atrial fibrillation but do not know it. Now a Dutch company has developed an app with which a smartphone can be used to detect this dangerous cardiac arrhythmia. Scientists at the TU Darmstadt are helping to ensure the recorded data is interpreted correctly and efficiently.
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Image: blood-patrolling monocytes (red) adhering to inflamed endothelium (green) in the inner curvature of the aortic arch of a mouse with incipient atherosclerosis; Copyright: CNIC

Blocking a protein could improve the effectiveness of intravascular cellular 'policing'


The study shows that blockade of the protease MT4-MMP increases the activity of blood-patrolling monocytes in the circulation.
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Depression linked to reduced arginine levels


People suffering from major depressive disorder, MDD, have reduced arginine levels, a new study from the University of Eastern Finland shows. Arginine is an amino acid which the body uses to produce, e.g., nitric oxide. Nitric oxide, in turn, is a nervous system and immune defence mediator, and it also plays a role in vascular regulation.
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Female sex not a protective factor against heart disease in type 1 diabetes


Constrictions of the coronary blood vessels is a possible consequence of type 1 diabetes, and one that can eventually lead to myocardial infarction or heart failure. Generally speaking, women are afflicted by coronary artery disease later than men, but if a woman has type 2 diabetes, the advantage is negated.
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Asthma drug potential treatment for aortic aneurysm


Aortic aneurysm – the dilation of the aorta – is a serious condition that lacks effective drug treatment. Researchers at Karolinska Institutet in Sweden report in the journal PNAS, however, that a common asthma drug can retard the development of aortic aneurysm in mice.
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Ohio University study shows Vitamin D3 could help heal or prevent cardiovascular damage


A new study conducted by Ohio University scientists suggests that a little more sunlight might help restore damage to your cardiovascular system.
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Premature birth associated with increased risk of heart disease in mothers


A study led by researchers at Keele University has found the risk of death in later life due to coronary heart disease doubles in women who give birth prematurely.
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Everyday exercise has surprisingly positive health benefits


The benefits of low-intensity physical activity, such as standing, walking or doing household chores, can be more health beneficial than once thought. According to a study from Karolinska Institutet published in the journal Clinical Epidemiology, replacing half an hour's sedentariness a day with everyday activity reduces the risk of fatal cardiovascular disease by 24 percent.
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Scientists uncover why sauna bathing is good for your health


Over the past couple of years, scientists at the University of Eastern Finland have shown that sauna bathing is associated with a variety of health benefits.
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"Spray-On" muscle fibers for biomimetic surfaces


Few patients with heart failure are fortunate enough to receive a donor's heart. Ventricular assist devices (or heart pumps) have been around for several years and are designed to buy time as patients wait for a transplant. Unfortunately, the body doesn't always tolerate these devices.
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"Preventicus Heartbeats": An app that's a clinically validated medical device


Stroke is the second leading cause of death in the world. Yet many incidences of stroke are preventable since they are frequently associated with an undetected abnormal heart rhythm. In this case, patients can benefit from using the clinically validated "Preventicus Heartbeats" app, which measures and documents the heart rhythm with a smartphone camera.
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MEDICA 2017: all about laboratory medicine at the MEDICA LABMED FORUM


If you are interested in laboratory medicine and come to the MEDICA 2017, you will quickly notice that Exhibition Halls 1 and 2 were demolished. A new state-of-the art hall is meant to take their place. Until then, exhibitors from the field of laboratory medicine will be showcased at their temporary new location in the lightweight hall structures 3a and 18 on the fairgrounds.
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Coronary heart disease: non-invasive imaging reduces catheter examinations


Coronary heart disease (CHD) can cause heart arrhythmia, heart insufficiency or heart attack. All the more important is an early, reliable diagnosis that helps to treat it and to reduce risk factors. But what is the best method for diagnosis? A recent study found that functional imaging methods can often spare patients the trouble and risks of a coronary angiography.
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Image: Collage of several MRI images of the heart, in which different locations are marked with red arrows; Copyright: University Hospital Münster/Ali Yilmaz

Myocarditis: more specific diagnosis thanks to molecular imaging


There are many causes of myocarditis or inflammation of the heart muscle. Oftentimes, the culprits are viruses or bacteria and sometimes even an acute heart attack. Regardless of the cause, it creates a challenge for cardiologists: a diagnosis tends to be only nonspecific without a biopsy. A cardiac MRI and molecular imaging promise to provide assistance.
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Collect Data? Utilize Data! – The Blessings of Big Data


Genome data, MRI images, and blood test results – data collected in the medical sector is not only very heterogeneous but also extremely extensive. However, it is important to not only collect this data but to also utilize it. After all, processed, linked and analyzed data provides many opportunities in research, hospital management and ultimately also for the individual patient.
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Sodium intake and blood pressure: too much salt is bad for you. What about too little salt?


Common salt – or sodium chloride – is essential as a stimulant for nerve conduction. What is more, sodium ions also regulate the water balance in the body. Yet when it came to salt consumption, for the longest time the rule was "less is more". However, a recent study publication calls this belief into question.
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Hemodialysis: Creating the AV fistula using catheters


For many patients, the start of hemodialysis marks the lifelong dependency on needing their blood purified. But before they can actually begin treatments, a blood vessel in the patient's arm needs to be enlarged to where it can move enough blood and withstand being connected to the dialysis machine several times per week.
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Emergency: app alerts first responders


Just a few minutes can make the difference between life and death when a person loses consciousness or goes into sudden cardiac arrest. Unfortunately, emergency medical services cannot always be on location as fast as needed. To ensure immediate life-sustaining measures, the "mobile rescue" app was developed, which alerts emergency medical responders in the immediate vicinity of an emergency.
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Cardiac insufficiency: early diagnosis with ultrasound


Heart failure or cardiac insufficiency presents an extra strain on patients because it severally limits everyday performance and deprives them of energy. Due to their intense need for movement, children are particularly strongly affected. However, the disease is frequently not detected until the physical performance is already declining. An early diagnosis could prevent this.
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Ultrasound: four dimensions for pediatric cardiac diagnostics


Fortunately, only a handful of newborns are affected by them, though this determines if not the rest of their lives then, at least, the first few years of affected children: congenital heart defects. After the necessary surgeries, the small patients repeatedly need to return for checkups. Until now, these were conducted using MRI scans. 4D ultrasound can be an alternative.
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Wanted: rapid test to prevent deep vein thrombosis


Deep vein thrombosis is not just a risk factor for frequent flyers but also for wearers of cardiovascular implants and newly operated patients. Blood thinners prevent these dangerous blood clots from forming, but they need to be carefully adjusted and do not work the same way in every patient. A detailed analysis of platelets (thrombocytes) could prevent complications in the future.
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ECG measurements: "Our chest strap moistens itself"


When measuring myocardial activity, it is important for the skin to always stay moist under the electrodes of the ECG. Only then can data be consistently transferred. Athletes have an easier time with this: they are used to sweating. This is a lot harder for older patients.
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Transcatheter Pacing System: The world’s smallest cardiac pacemaker


In the case of cardiac arrhythmia, the normal heart rate gets out of balance due to various reasons. In some cases, it is necessary to implant a cardiac pacemaker. Just like with any intervention, this type of surgery also involves risks. In the worst-case scenario, this can lead to abnormal wound healing or obliteration of the vascular system.
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MEDICA EDUCATION CONFERENCE: Preventing diabetes from affecting the kidneys


November 14, 2014 is World Diabetes Day – and MEDICA is also concerned with this metabolic disorder: several lectures at the MEDICA EDUCATION CONFERENCE are dedicated to the so-called “sugar disease” that affects 382 million people worldwide. The Conference addresses the damages caused by the disease, its prevention and therapy.
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Football: "We want to globally determine deaths for the first time"


Sudden deaths of football players make headlines time after time: competitive athletes who are the idols of many people die just when they are on the playing field and in the limelight. Congenital heart defects often cause their death. Sports physicians and FIFA now plan to ascertain data that can help improve preventive examinations in competitive football.
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Vascular health in athletes


"Sports are good for your health", as the saying goes. Regular exercise promotes the health of our blood vessels and prevents vascular diseases. However, many years of competitive sports can also have negative effects on vascular health and increase the risk of myocardial infarction. Prof. Martin Halle of the Technical University Munich explains at what athletes need to pay attention to.
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