21/09/2018A team of researchers at the University of Cologne's Faculty of Medicine and the German Center for Infection Research (DZIF) has achieved a scientific breakthrough in the accelerated diagnosis of multi-resistant hospital pathogens. Using a novel immunochromatographic method, the researchers detected bacteria that are resistant to the antibiotic group carbapenemes.
31/07/2018Patients with spinal fractures caused by tumors or osteoporosis usually undergo a procedure called kyphoplasty, where the fracture is filled with surgical cement. While kyphoplasty can stabilize the bone, cancer patients are still often left with spinal column tumors that are very hard to reach with conventional chemotherapy, which has to cross the blood-brain barrier when delivered intravenously.
27/07/2018Scientists at the Mainz University Medical Center and the Max Planck Institute for Polymer Research (MPI-P) have developed a new method to enable miniature drug-filled nanocarriers to dock on to immune cells, which in turn attack tumors. In the future, this may lead to targeted treatment that can largely eliminate damage to healthy tissue.
27/07/2018A new special issue of SLAS Discovery reflects examples of the recent groundswell of creative new applications for high-throughput flow cytometry (HTFC) in drug discovery.
24/07/2018Scientists from the University of Freiburg have developed materials systems that are composed of biological components and polymer materials and are capable of perceiving and processing information.
24/07/2018Harvard University researchers have bioengineered a three-dimensional model of a human left heart ventricle that could be used to study diseases, test drugs and develop patient-specific treatments for heart conditions such as arrhythmia.
16/07/2018The rise of genomics, the shift from considering genes singly to collectively, is adding a new dimension to medical care; biomedical researchers hope to use the information contained in human genomes to make better predictions about individual health, including responses to therapeutic drugs.
13/07/2018Last month alone, 23 percent of Americans took two or more prescription drugs, according to one CDC estimate, and 39 percent over age 65 take five or more, a number that's increased three-fold in the last several decades. And if that isn't surprising enough, try this one: in many cases, doctors have no idea what side effects might arise from adding another drug to a patient's personal pharmacy.
09/07/2018Designing new molecules for pharmaceuticals is primarily a manual, time-consuming process that's prone to error. But MIT researchers have now taken a step toward fully automating the design process, which could drastically speed things up - and produce better results.
22/05/2018This unusual ally can be extremely valuable in the fight against inflammation in the body: CO (carbon monoxide). As a therapeutic gas, it also promises relief for inflammatory gastrointestinal diseases. Having said that, it is difficult to transport the active ingredient to the exact desired location.
22/02/2018Here on Earth, all experiments are bound by gravitation. Yet, freed from gravity's grip, tumor cells, for example, behave in an entirely different way. As part of the "Thyroid Cancer Cells in Space" project by the University of Magdeburg, smartphone-sized containers carrying poorly differentiated thyroid cancer cells are sent into space.
01/08/2017Many therapeutic drugs are very powerful, but they are also very toxic at the same time. Thus, they have to be measured regularly, again and again, so that an adjustment of the individual drug dosage can be made. Until now, the "normal" way was to take the blood sample, send it to a central laboratory and get the results after some days. A new point-of-care test can measure it in 15 minutes.
01/12/2016A German proverb says, "Old age is like a hospital that accepts all diseases," and medicine confirms that older people are not only considerably more susceptible to infectious diseases than they were in middle age, but that body and mind are also less resilient and recover slower or not at all from adverse effects or injuries.
04/01/2016Most Europeans think it was a long time ago, but the residents of West Africa clearly feel the consequences of the Ebola epidemic that broke out in December 2013 and still continues today. So far, approximately 11,300 people have died as a result of the outbreak; more than 28,000 contracted the disease.
01/12/2015Each year, approximately 250,000 Germans suffer a stroke. This makes stroke the third leading cause of death after heart disease and cancer. The circulatory disorder that occurs in the brain is normally treated using systemic thrombolysis, a procedure that bears various risks. Unlike mechanical thrombectomy, which offers clear advantages by comparison.
03/08/2015Malignant tumors can be fought with X-rays – usually with radiation therapy from outside the body. Nuclear medicine physicians can also accomplish this inside the body with radioactive materials, called radiopharmaceuticals. They also offer big benefits for clinical diagnostics as long as a specific target can be assigned to them.
03/08/2015Endoradiotherapy can be very unpleasant for cancer patients, since it does not only harm tumor cells, but also healthy ones. Sometimes, patients even need to stop therapy because of the side effects. Physicians and researchers are thus continuously searching for ways to transport radiopharmaceuticals directly and exclusively to their target.
01/07/2015Deep vein thrombosis is not just a risk factor for frequent flyers but also for wearers of cardiovascular implants and newly operated patients. Blood thinners prevent these dangerous blood clots from forming, but they need to be carefully adjusted and do not work the same way in every patient. A detailed analysis of platelets (thrombocytes) could prevent complications in the future.
01/06/2015A tumor is as unique as the person who is affected by it. For a long time, it was assumed this would make treatment more difficult since cancer drugs are not able to be one hundred percent effective in targeting the affected cells. In this interview with MEDICA.de, Professor Ugur Sahin explains why it is precisely these individual mutations that make him hopeful for a new type of therapy.
01/12/2014Several weeks ago on November 1, 2014, 29-year-old Brittany Maynard, who suffered from terminal brain cancer, took drugs to end her life surrounded by her family. This was preceded by months of despair and anguish, but also by love and a lust for life as the young woman describes in several videos she recorded to fight for the right to die with dignity.