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Image: schematic of Mechanism of immune escape by P. falciparum; Copyright: Osaka University

Discovery of key molecules involved in severe malaria – A new target for malaria vaccine

12/12/2017

Malaria is one of three major infectious diseases affecting approximately 300 million people every year, accounting for about 500,000 deaths, but effective vaccine development has not been successful.
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Image: Val223 and Phe258 of SPP interact with the inhibitors for SPP and γ-secretase. (Lower panel) The inhibitor prevents proliferation of protozoa in toxoplasma infect ; Copyright: Osaka University

Dibenzoazepine defender: Drug found to be effective against resistant Hepatitis C

07/12/2017

Osaka University researchers identify class of chemicals that can combat resistant strains of the hepatitis C virus, as well as parasites that cause malaria and toxoplasmosis.
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Image: a row of small glass bottles, in one of them there is a syringe; Copyright: panthermedia.net/NikiLitov

Study opens new avenue in quest to develop TB vaccine

27/11/2017

A team of scientists led by the University of Southampton has taken an important step forward in research efforts that could one day lead to an effective vaccine against the world's deadliest infectious disease.
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Image: blowflies on plants; Copyright: NTU Singapore

Flies could help to monitor disease outbreaks by acting as 'autonomous bionic drones' suggest scientists

27/11/2017

An international research team led by Nanyang Technological University, Singapore (NTU Singapore) have proposed that swarms of flies can be used to help monitor disease outbreaks. This follows their research that shows how whole communities of bacteria – known as a microbiome – can “hitch a ride” on common carrion flies and can be transferred to any surface where the flies land.
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Image: Graphic of round bacteria in a human vessel; Copyright: panthermedia.net/lightsource

Managing antibiotics not enough to reverse resistance

24/11/2017

Researchers have discovered that reducing the use of antibiotics will not be enough to reverse the growing prevalence of antibiotic resistance for some types of bacteria.
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Image: health workers tend to a patient in one of Sierra Leone's military hospitals; Copyright: Kawaoka Lab, UW-Madison

Unlocking the secrets of Ebola

21/11/2017

Scientists identify biomarkers that indicate likelihood of survival in infected patients.
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Image: Laboratory technician holds a Petri dish; Copyright: Fraunhofer ITEM

Fraunhofer launches a pioneering collaboration with iCAIR project

20/10/2017

Bacteria keep developing new resistances to antibiotics. There is a desperate need for new medications. The biggest hurdle in developing these new medications is getting them from the laboratory and into clinical trials. iCAIR will use selected lighthouse projects to establish and demonstrate its position as an expert preclinical development platform for new anti-infective drugs.
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Image: A healthy liver cell and a HCV-infected liver cell in comparison; Copyright: Marianne Doré Hansen & Marit Anthonsen

How hepatitis C hides in the body

17/10/2017

The Hepatitis C (HCV) virus is a sly enemy to have in one’s body. Not only does it manage to make itself invisible to the immune system by breaking down communication between the immune cells, it also builds secret virus "factories" that quickly go into mass production.
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Image: A volunteer receives an injection in the PREVAIL Ebola vaccine clinical trial; Copyright: PREVAIL

Experimental Ebola vaccines elicit year-long immune response

16/10/2017

Results from a large randomized, placebo-controlled clinical trial in Liberia show that two candidate Ebola vaccines pose no major safety concerns and can elicit immune responses by one month after initial vaccination that last for at least one year.
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Image: Vials in a rack; Copyright: Messe Düsseldorf

MEDICA 2017: all about laboratory medicine at the MEDICA LABMED FORUM

02/10/2017

If you are interested in laboratory medicine and come to the MEDICA 2017, you will quickly notice that Exhibition Halls 1 and 2 were demolished. A new state-of-the art hall is meant to take their place. Until then, exhibitors from the field of laboratory medicine will be showcased at their temporary new location in the lightweight hall structures 3a and 18 on the fairgrounds.
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Image: X-ray image of a human chest, showing the lungs; Copyright: panthermedia.net/Guzel

Respiratory diseases, musculoskeletal conditions, depressive symptoms and diabetes

22/09/2017

Respiratory diseases are major causes of disease burden and mortality. They are also the focus of the latest issue of the Journal of Health Monitoring, which features a Focus article that considers acute respiratory diseases such as influenza as well as chronic lung diseases including lung cancer, chronic obstructive pulmonary disease (COPD) and asthma.
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Image: flu vaccination standing on the table; Copyright: Lancaster University

Why only half of healthcare workers have the flu vaccine

20/09/2017

The low uptake of flu vaccination among medical students and doctors is influenced by social attitudes say researchers. Despite a recommendation from the Chief Medical Officer for England that all healthcare workers are vaccinated annually, only 55 percent are protected against the spread of influenza, this could contribute to staff sickness and mortality among elderly patients.
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Image: Collage of several MRI images of the heart, in which different locations are marked with red arrows; Copyright: University Hospital Münster/Ali Yilmaz

Myocarditis: more specific diagnosis thanks to molecular imaging

01/09/2017

There are many causes of myocarditis or inflammation of the heart muscle. Oftentimes, the culprits are viruses or bacteria and sometimes even an acute heart attack. Regardless of the cause, it creates a challenge for cardiologists: a diagnosis tends to be only nonspecific without a biopsy. A cardiac MRI and molecular imaging promise to provide assistance.
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Image: woman holding a sketch of a human lung; Copyright: panthermedia.net/Monkeybusiness

Molecular Microsystems: Preventing Exacerbations of Asthma and COPD

01/08/2017

An increasing percentage of the world population suffers from chronic inflammatory disorders of the respiratory system. Acute attacks often lead to a worsening of the disease and considerably reduce the patient’s lung volume. Nine institutes of a research alliance under the Leibniz Institute umbrella are working on technologies designed to predict and thus prevent exacerbations.
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Image: A petri dish with yellow bacterial cultures on a black ground; Copyright: panthermedia.net/kwanchaichaiudom

Laboratory medicine: confronting infections with speed and foresight

03/04/2017

The laboratory is one of the most important and pivotal bastions in patient care. In the laboratory, acute, chronic and genetic diseases are diagnosed, the progression of diseases such as diabetes is regularly checked or specialists look for biomarkers to adapt cancer therapies.
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Image: Demonstrator; Copyright: Leibniz-IPHT

Medical imaging is onto septic fungi

03/04/2017

Instant treatment is absolute vital for patients developing sepsis. Providing a specific therapy early on is key. To manage this the pathogenic organisms need to be identified accurately. But a fungal sepsis can still be a hard nut to crack.
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Image: Graphic representation of Europe with small figures depicting the population; Copyright: panthermedia.net/Takahase Segundo

Hospital-acquired infections: pathogens know no borders

03/04/2017

Many aspects are uniformly regulated in Europe, however, hospital hygiene and MRSA prevention, for example, are not. The Netherlands plays a pioneering role in the fight against hospital-acquired infections. The country is an often-cited role model. But can other countries simply adopt the same system? And what makes it so different? MEDICA asked expert Prof. Alexander W. Friedrich.
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Image: Single room with a window in a hospital; Copyright: panthermedia.net/epstock

Hospital construction: infection prevention through architecture?

09/01/2017

Hospitals apply many infection prevention and control measures. They all have one thing in common: they are individual parts of an overall concept that is aimed at preventing the spread of highly infectious and resistant pathogens in hospitals. Nevertheless, previous hygiene concepts ignore one aspect of hospitals: the architecture of the actual hospital facility itself.
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Image: Graphic of an ebola virus against a blue background; Copyright: panthermedia.net/krishna creations

Who am I? Viruses on Nanosprings

21/12/2016

Within the scope of the VIRUSCAN project that is funded by the Horizon 2020 Research and Innovation Program of the European Union, Dr. Charlotte Uetrecht from Hamburg/Germany investigates individual viruses to be able to later identify them on a nanospring structure. MEDICA.de wanted to know: how does this work?
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Photo: Hospital  bed

Textiles used in hospitals and medical offices – germs don’t stand a chance

01/06/2016

Some hospitals have long banned the status symbol of physicians – the white coat. Research has shown that especially the sleeves were contaminated with various types of bacteria. But it’s not just lab coats that can spread germs in healthcare settings. This field uses a variety of different textiles. Wouldn’t it, therefore, make sense to apply antimicrobial finishes?
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Photo: physicians at station

Gram-negative bacteria pose a major challenge for hospitals

01/06/2016

Every day, people are admitted to the hospital, discharged or they visit patients. This large number of people increases the risk of bacteria transmission. Preventative measures such as short-sleeved uniforms and copper surfaces can help by improving hospital hygiene but they cannot replace the legal requirements for hygiene measures.
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Photo: Researcher is looking at a microfluidic LabDisc

Point-of-care-testing: from disc to diagnosis

22/02/2016

Easy solutions that deliver results quickly are a great asset in medicine: patients receive their diagnosis faster and physicians have more time to treat them. Such tools also work without sophisticated resources and trained personal. A device currently developed in a project funded by the European Commission could bring all of this to point-of-care-testing for infectious diseases.
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Graphic of the operation

Filling bone defects – replacement tissue with its own blood supply

01/02/2016

First grow tissue in the lab, then insert it into patients when they need it and you’re done! Unfortunately, things are not as easy as people hoped at the onset of “tissue engineering”. Although robust tissues for bone defects can be grown in a petri dish, for example, they unfortunately quickly die off again inside the body if there is no corresponding nutrient supply.
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Photo: white jeep

Rapid Tests: valuable helpers for use in the field

04/01/2016

Infectious diseases are widespread in conflict areas. When basic medical care is lacking on location, people cannot be appropriately treated. Laboratory tests are limited in the field. Rapid diagnostic tests make it possible for medical personnel to quickly and accurately test patients for several infectious diseases, for instance for the presence of malaria or HIV infection.
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Photo: Pregnancy test

Disaster medicine or disastrous medicine?

04/01/2016

Most Europeans think it was a long time ago, but the residents of West Africa clearly feel the consequences of the Ebola epidemic that broke out in December 2013 and still continues today. So far, approximately 11,300 people have died as a result of the outbreak; more than 28,000 contracted the disease.
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Photo: Ebola test

Ebola: detection strips instead of lab tests

04/01/2016

When infectious diseases such as Ebola break out, a rapid diagnosis is important because the early detection of a virus along with the right hygiene measures can prevent its continued spread. However, laboratories and skilled personnel are not available everywhere. Low-cost and portable detection strips can bring relief.
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Hospitals: many small measures against infections and sepsis

01/08/2014

If neither the immune system nor antibiotics are able to control an infection, a sepsis can arise out of it - an infection that attacks several organs at the same time and causes the immune system to overreact. This is a life-threatening condition.
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Hygiene: "The sensor applies the principle of so-called photonic structures"

01/08/2014

Detecting infections quickly and reliably with the naked eye: This is what many doctors in hospitals and in the doctor's surgeries wish for. To make this dream come true, Prof. Holger Schönherr, a scientist from Siegen, is researching a sensor that should show an infection by a color change.
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Multi-resistant bacteria want to conquer the world

01/08/2014

Bacteria lurk everywhere: on the skin, in the intestines and in every puddle. Most of them that are hanging out in the human body are good bacteria. But not all of them. Those pathogens that exhibit resistance and are thus very hard to combat are the most dangerous kind. Their spread threatens people all over the world.
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"The immunosensory system goes beyond the actual immune cells"

22/01/2014

It guards the body but can become its enemy: the immune system defends us from intruding pathogens; it is also able to cause severe diseases if it falsely recognizes the body itself as a threat. Molecular receptors in the whole body enable the immune system to “sense” what happens within.
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"The Virus Manipulates the Host Cell on Different Levels"

08/01/2014

Heart diseases can be triggered by special viruses that affect the cardiac muscle. Preventive drugs could definitely be developed – if the virus does not mutate.
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