23/04/2018Using a Raman microscope, researchers at Ruhr-Universität Bochum have studied at which targets the cancer drug Neratinib binds in cells and how its chemical structure changes. Compared with other techniques, this method offers a considerable advantage, as it is not necessary to apply a label to the drug that would indicate its distribution indirectly; rather, the drug itself can be monitored.
10/04/2018Hosted by Charité – Universitätsmedizin Berlin, the TrueBrainConnect project aims to systematically study connections between different areas of the brain, and hopes to draw conclusions regarding potential disease patterns.
09/04/2018MPI-P group leader Sapun Parekh and Brown University Professor Nick Fawzi have received $750,000 from the Human Frontier in Science Program (HFSP) over the next 3 years to study the "Structure and biophysics of disordered domains mediating RNP granules: from atoms to cells".
26/03/2018A team from the Research Institute of McGill University Health Centre (RI-MUHC) in Montreal has joined forces with researchers at Johns Hopkins to bring screening and early detection of ovarian and uterine cancers one step closer to clinical implementation. Researchers developed a test that provides a safe and minimally invasive method for earlier diagnosis of ovarian and endometrial cancers.
16/03/2018Metabolic changes in cells can occur at the earliest stages of disease. In most cases, knowledge of those signals is limited, since we usually detect disease only after it has done significant damage.
15/03/2018Working with cells grown in the lab, Johns Hopkins researchers have identified a biochemical pathway that allows a structure within cells, called the Golgi apparatus, to combat stress caused by free radicals and oxidants. The research team showed that this pathway can be activated by a drug called monensin, which is commonly used as an antibiotic in animal feed.
14/03/2018Brown adipose tissue has played a key role in prevention research since its presence was first documented in adults. However, there was no non-invasive method of measuring its heat generation. A team at the Technical University Munich (TUM) and the Helmholtz Zentrum München has now succeeded in making the activity of brown adipose tissue visible without injecting substances.
08/03/2018Automation makes work life easier in many ways but is it also a solution for analyzing medical images? Is a computer actually reliable enough to assist in the medical decision making process? Researchers in Landshut examine how machine learning algorithms can work more reliably and support radiologists.
02/03/2018UZH researchers have discovered a previously unknown way in which proteins interact with one another and cells organize themselves. This new mechanism involves two fully unstructured proteins forming an ultra-high-affinity complex due to their opposite net charge. Proteins usually bind one another as a result of perfectly matching shapes in their three-dimensional structures.
27/02/2018Key repeating moments in the film give viewers the information they need to understand the storyline. The scenes cause identical reactions in the viewer's brain. The results deepen our understanding of how the brain functions, how narratives work in film, and memory mechanisms impaired by conditions such as Alzheimer's disease.
16/02/2018Scientists from the University of Zurich have succeeded for the first time in tracking individual stem cells and their neuronal progeny over months within the intact adult brain. This study sheds light on how new neurons are produced throughout life.
08/02/2018When body tissue is reconnected during a tumor operation in the gastrointestinal tract, surgeons need information about the current state of these so-called anastomoses. The new, non-invasive hyperspectral imaging technology now makes it possible to measure the crucial parameters during surgery and thereby increase surgical precision.
04/01/2018The position and alignment of surgical tools in the patient’s body must always be kept in view during the operation process to guarantee success and safety. With fine sensors at the tip of the instruments and an electromagnetic signal, Fiagon's electromagnetic navigation systems accurately reproduce their position in the body.
04/01/2018Imaging, navigation, integration – these are terms that describe the modern operating room. All of these components play a key role in accurate surgical procedures. They are integrated into surgical navigation systems, which make complicated medical surgeries considerably safer.
04/01/2018While it is commonplace for operating room staff to work together as a team, the collaboration of operating room systems does not always work so well – many devices are still separated from one another, causing the OR processes to be prone to mistakes. The same applies to surgical navigation technologies that represent the interface between imaging, the surgeon and therapeutic devices.
23/10/2017According to the WHO, 300 million people throughout the world are affected by lymphedema. This condition occurs when fluid that flows between cells is no longer transported back into the blood circulation and accumulates in the skin. Triggers can be surgeries, injuries or genetic defects for example. A new microscopy technique could now also indicate the causes.
01/09/2017Coronary heart disease (CHD) can cause heart arrhythmia, heart insufficiency or heart attack. All the more important is an early, reliable diagnosis that helps to treat it and to reduce risk factors. But what is the best method for diagnosis? A recent study found that functional imaging methods can often spare patients the trouble and risks of a coronary angiography.
01/09/2017There are many causes of myocarditis or inflammation of the heart muscle. Oftentimes, the culprits are viruses or bacteria and sometimes even an acute heart attack. Regardless of the cause, it creates a challenge for cardiologists: a diagnosis tends to be only nonspecific without a biopsy. A cardiac MRI and molecular imaging promise to provide assistance.
01/09/2017Many people are affected by heart disease today because - among other reasons- our modern unhealthy lifestyle is taking a toll on our hearts. A reliable diagnosis and treatment are crucial for patients with heart disease since all other organs depend on the pumping of our vital organ. Modern imaging techniques are a key to understanding the heart.
22/08/2017Physics has always supported medical science, especially when it comes to practical implementation. Now physicists and health professionals join in collaborative research at an interdisciplinary Center in Erlangen and incorporate fundamental principles of theoretical physics in their studies of diseases.
10/07/2017Radiation therapies are an essential component of today’s oncology because they enable the treatment of localized tumors. Yet they have one major drawback: radiation damages not just tumor cells but also healthy tissue. One solution to solve this problem could be proton minibeam therapy, which uses finely focused beams.
03/07/2017Precision work is absolutely essential in eye surgery since the surgical site is very minute and sensitive. This is why eye surgeons have been using lasers for years. Femtosecond lasers are especially well suited to serve this purpose because they are able to cut tissue with great precision and little energy, which prevents unwanted side effects of surgery.
03/07/2017The scalpel is considered the classic surgical instrument and as such, has remained unchanged for quite some time. However, today’s technology opens up a world of new possibilities for cutting tissue. Next to high-frequency electrosurgical scalpels that work with electric power, surgeons also use a variety of different lasers. They promise great usability and better treatment.
24/04/2017Liver cancer is the fifth most common malignant tumor in the world. The tumor can be removed through surgery or by utilizing thermal ablation techniques. If a treatment with conservative methods is no longer possible, there is an alternative: irreversible electroporation (IRE). The effectiveness of this method was now confirmed by a clinical study.
03/04/2017Instant treatment is absolute vital for patients developing sepsis. Providing a specific therapy early on is key. To manage this the pathogenic organisms need to be identified accurately. But a fungal sepsis can still be a hard nut to crack.
08/03/2017Pneumonia is the most frequent respiratory disease in children and can even cause death. That is why it is extremely important to make an accurate diagnosis as quickly as possible. If this requires imaging tests, normally X-rays are taken. But there is an alternative: ultrasound.
21/12/2016Within the scope of the VIRUSCAN project that is funded by the Horizon 2020 Research and Innovation Program of the European Union, Dr. Charlotte Uetrecht from Hamburg/Germany investigates individual viruses to be able to later identify them on a nanospring structure. MEDICA.de wanted to know: how does this work?
08/12/2016Watching millions of neurons in the brain interacting with each other – for a long time this was possible only to a limited extent. The current techniques can visualize only superficial layers or the imaging they use is too slow. But now, Prof Daniel Razansky and his team have found a new method to visualize the brain activity – by using optoacoustics.
08/09/2016For many patients, the start of hemodialysis marks the lifelong dependency on needing their blood purified. But before they can actually begin treatments, a blood vessel in the patient's arm needs to be enlarged to where it can move enough blood and withstand being connected to the dialysis machine several times per week.
01/09/2016Patients take center stage during surgery. Their treatment should be as gentle and effective as possible, which is why there is a trend towards minimally invasive surgery (MIS). But minimal procedures require better supporting technologies. The hybrid operating room combines surgery and imaging systems and increasingly replaces conventional open surgery approaches with MIS.
01/09/2016Monitoring individual results during surgery with an angiography system? This is already an option in approximately 200 hospitals in Germany. Thanks to intraoperative imaging, major medical procedures can be replaced by minimally invasive surgery because physicians are able to monitor the results immediately. This is gentler on patients and decreases the number of subsequent revision surgeries.
01/09/2016When it comes to the future of medicine, we often ponder how we would like to be treated. On the other hand, there is the issue of how physicians would like to treat their patients. The surgical procedures are determined by the technology that doctors are surrounded by. That’s why technology development also needs to be adapted to the needs of surgeons in the operating room of the future.
22/08/2016A beautiful field of flowers, a trip to the beach or a visit to the zoo. Children can experience all of these at the Clinical Center Dortmund in a 270- degree projection on the wall. The Center created a space that is designed to help its little patients overcome their fear of MRI scans.
02/05/2016Heart failure or cardiac insufficiency presents an extra strain on patients because it severally limits everyday performance and deprives them of energy. Due to their intense need for movement, children are particularly strongly affected. However, the disease is frequently not detected until the physical performance is already declining. An early diagnosis could prevent this.
01/03/2016Fortunately, only a handful of newborns are affected by them, though this determines if not the rest of their lives then, at least, the first few years of affected children: congenital heart defects. After the necessary surgeries, the small patients repeatedly need to return for checkups. Until now, these were conducted using MRI scans. 4D ultrasound can be an alternative.
01/03/2016Every little thing can be a matter of life or death for premature babies. That is why the right diagnosis plays an extremely important role. This includes examining infants with an MRI scan. Until now, sliding premature babies into an MRI scanner without an incubator was only possible to a limited degree. Now this problem could be solved.
02/11/2015Performing surgery in a hybrid operating room is meant to be a relief for the staff and offer patients new options for treatment. What is actually so different about this hybrid operating room, what can you expect and what should you keep in mind during the planning process?
01/10/2015It is a portmanteau, a mixture of two words. This way it saves us time and trouble while speaking because the human speech apparatus is lazy. And it describes a mixture of procedures: the combination of two procedures that would normally be separate in medicine. We are talking about theranostics.
01/10/2015A proper diagnosis is a part of great therapy. However, it can also be beneficial to be able to quickly respond to changes during a treatment. One example of this is the treatment of uterine myomas. Female patients at the University Hospital Bonn are treated using so-called high-intensity focused ultrasound, HIFU in short. Prof. Holger Strunk explains this procedure.
01/09/2015They can be seen everywhere: at the wrists, in the ear, clipped to the belt. Wearables are small technical assistants who are built to collect and partially also to analyze data. Some of them collect measurable health data, others "only" count their user’s steps or measure the surrounding UV radiation. The fact is, however, that wearables are en vogue and are used for many different cases.
03/08/2015Endoradiotherapy can be very unpleasant for cancer patients, since it does not only harm tumor cells, but also healthy ones. Sometimes, patients even need to stop therapy because of the side effects. Physicians and researchers are thus continuously searching for ways to transport radiopharmaceuticals directly and exclusively to their target.
03/08/2015Nuclear medicine physicians use so-called gamma cameras for myocardial perfusion scintigraphy. The devices record radioactive substances that are injected into the patient and show changes in the heart muscle (myocardium). Now a new gamma camera is able to record images faster and by using much less radiation.
03/08/2015Malignant tumors can be fought with X-rays – usually with radiation therapy from outside the body. Nuclear medicine physicians can also accomplish this inside the body with radioactive materials, called radiopharmaceuticals. They also offer big benefits for clinical diagnostics as long as a specific target can be assigned to them.
04/05/2015Whether it is a mammogram, colonoscopy or a skin cancer screening – after a certain age, we are subject to various early cancer detection screenings. Yet many of us don’t know that these screening tests are also associated with risks. This is something what Dr. Sylvia Sänger from the University Medical Center Hamburg-Eppendorf discovered in a study.
01/10/2014On November 10, 2014, astronaut Alexander Gerst will return to Earth from the International Space Station (ISS). He is not just anxiously expected by his family, but also by Dr. Anna-Maria Liphardt from the Institute of Biomechanics and Orthopedics at the German Sport University Cologne
01/10/2014Herniated discs can have very different effects: some cause no discomfort and are only discovered by accident; others can cause paralysis or cause patients to be in great pain. For the most part, these problems develop suddenly after an awkward movement – at least that is what patients report.
02/06/2014Sudden deaths of football players make headlines time after time: competitive athletes who are the idols of many people die just when they are on the playing field and in the limelight. Congenital heart defects often cause their death. Sports physicians and FIFA now plan to ascertain data that can help improve preventive examinations in competitive football.
04/03/2014Prenatal care, cancer check-up, vascular examinations – sonography is versatile, provides reliable imaging to physicians and does not tax patients with radiation. It is comprehensively available, from doctor’s office to university medical center. A sound continuing education of sonography users is essential for good diagnostics, also since different devices have different strong points.
03/02/2014Shortening a time-consuming procedure from four hours to five minutes and automate it at the same time sounds like a dream come true for employees in all fields and industry sectors. This dream could soon become a reality for radiologists. Software could take away the tedious processing of CT images, which is required before cancer radiation therapy.
03/02/2014Radiologists usually do their work after oncologists when it comes to cancer treatment. Yet modern radiology also provides treatments at this point. MEDICA.de spoke with Professor Stefan Schönberg, Director of the Institute of Clinical Radiology and Nuclear Medicine at the University Medical Center Mannheim, Germany, about the use of a new computer tomograph and its benefits for patients.