18/01/2019Researchers have developed a new way to image the brain with unprecedented resolution and speed. Using this approach, they can locate individual neurons, trace connections between them, and visualize organelles inside neurons, over large volumes of brain tissue.
14/01/2019There are many times when our cells need to move. Mobile cells guide our body's formation (embryonic development). Immune cells roam to capture unwanted intruders. And healing cells (fibroblasts) migrate to mend wounds. But not all movement is desirable: Tumors are most dangerous when cancer cells gain the ability to travel throughout the body (metastasis).
07/01/2019A team of University of Illinois at Urbana-Champaign researchers led by Prof. Stephen Boppart has successfully visualized the tumor microenvironment of human breast tissue after it was surgically removed from a patient in the operating room by using a new portable optical imaging system. This work marks a major step toward providing cancer researchers with a tool for tracking tumor progression.
03/01/2019The National Science Foundation BIGDATA program awarded $1,200,000 to a research team led by the University of Pittsburgh Swanson School of Engineering to study the big brain data for complex brain disorders and design new algorithms that address computational challenges in multi-site collaborative data mining.
21/12/2018Extremely obese people are needing a far higher dose of radiation during x-ray examinations than people of normal weight, increasing their risk of cancer, new research has shown.
21/12/2018A team of University of Illinois at Urbana-Champaign researchers led by Professor Stephen Boppart has successfully visualized the tumor microenvironment of human breast tissue shortly after it was surgically removed from a patient in the operating room. The researchers achieved this using a new portable optical imaging system developed in Boppart's lab.
20/12/2018In mammals, generation of new neurons (neurogenesis) is mainly limited to early childhood and occurs in adulthood only in a few regions of the forebrain. One such exception is olfactory neurons, which develop from stem cells via several intermediate stages.
19/12/2018Does expansion microscopy deliver true-to-life images of cellular structures? That was not sure yet. A new publication in "Nature Methods" shows for the first time that the method actually works reliably.
19/12/2018Continuous monitoring is an essential process with every disease. In the case of eye disorders, frequent retina measurements can facilitate early detection of deterioration to quickly initiate intervention. This calls for comprehensive care settings, easy ways to take measurements and prompt results. However, in reality, this is rarely the case.
18/12/2018Tools allow scientists to understand the activity of naturally occurring microbiomes in response to real-world conditions and diet
18/12/2018Researchers find an effective way to treat an underdiagnosed condition that can cause heart attack and heart-attack-like symptoms.
13/12/2018Researchers at Stanford University, Palo Alto, California, have created a noninvasive technology that detects when nerve cells fire based on changes in shape. The method could be used to observe nerve activity in light-accessible parts of the body, such as the eye, which would allow physicians to quantitatively monitor visual function at the cellular level.
11/12/2018In a study published in Neuron, Emilie Macé from Botond Roska’s group and collaborators demonstrate how functional ultrasound imaging can yield high-resolution, brain-wide activity maps of mice for specific behaviors. The non-invasive technology has promising applications for ophthalmologic, neurologic and psychiatric diseases.
06/12/2018In the diagnosis of Alzheimer's disease and the search for effective treatments, tau tangles in the brain have joined amyloid build-up as markers of the disease and potential therapy targets. In the December issue of The Journal of Nuclear Medicine, the featured article of the month reports on the identification of a promising second-generation positron emission tomography (PET) tracer.
05/12/2018Using precise brain measurements, Yale researchers predicted how people's eyes move when viewing natural scenes, an advance in understanding the human visual system that can improve a host of artificial intelligence efforts, such as the development of driverless cars, said the researchers.
30/11/2018Researchers from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) have found a method for obtaining high-quality images in magnetic resonance imaging (MRI), that requires less contrast medium compared to current methods. An “elastic” protein structure can absorb dissolved xenon in a self-regulating way: The greater the amount of this noble gas, the higher the quality of the image.
28/11/2018Investigators at the Martinos Center for Biomedical Imaging at Massachusetts General Hospital (MGH) have used magnetoencephalography (MEG) - a technology that measures brain activity by detecting the weak magnetic fields produced by the brain's normal electrical currents - to measure levels of the iron-based mineral called magnetite in the human brain.
26/11/2018Colorectal cancer is the third most common form of cancer in the world. Every year in Finland, approximately 3,000 new cases are diagnosed, and roughly 1,200 patients die of it. Between 2004 and 2016, an extensive screening programme was conducted in Finland, intending to study the potential benefits and downsides of a nation-wide screening for colorectal cancer.
23/11/2018A research team headed by Prof. Frank Stienkemeier and Dr. Lukas Bruder of the University of Freiburg’s Institute of Physics has succeeded for the first time in applying 2D-spectroscopy to isolated molecular systems and thus in tracing the interactive processes at a molecular level more precisely.
23/11/2018Biotechnologists at Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) have developed a system to accurately measure muscle weakness caused by structural changes in muscle tissue. The new method allows muscle function to be assessed using imaging without the need for sophisticated biomechanical recordings and could in future even make taking tissue samples for diagnosing myopathy superfluous.
22/11/2018MRI brain scans perform better than common clinical tests at predicting which people will go on to develop Alzheimer's disease, according to a study being presented next week at the annual meeting of the Radiological Society of North America (RSNA).
19/11/2018Scientists at the National Synchrotron Light Source II (NSLS-II) – a U.S. Department of Energy (DOE) Office of Science User Facility at DOE's Brookhaven National Laboratory – have used ultrabright x-rays to image single bacteria with higher spatial resolution than ever before.
09/11/2018Current standard imaging techniques for initial staging of prostate cancer often underestimate the extent of disease beyond the prostate. A study featured in The Journal of Nuclear Medicine's November issue demonstrates that prostate-specific membrane antigen (PSMA) positron emission tomography/computed tomography (PET/CT) can pinpoint prostate cancer locations with superior accuracy.
07/11/2018Artificial intelligence (AI) technology improves the ability of brain imaging to predict Alzheimer's disease, according to a study published in the journal Radiology.
02/11/2018It's time: the world's largest medical trade fair opens its doors from 12 to 15 November. More than 5,000 international exhibitors will present their new innovative products and applications. Frums, conferences and special shows will feature exciting specialist lectures and discussions that will give you an insight into electromedicine, laboratory medicine, medical technology and diagnostics.
26/10/2018Medical imaging, such as X-ray or computerised tomography (CT), may soon be cheaper and safer, thanks to a recent discovery made by chemists from the National University of Singapore (NUS).
25/10/2018More than 60 million people in the U.S. suffer from disorders in the gastrointestinal tract that could be cured by electrical stimulation, but scientists don't fully understand the therapy's effects on a critical organ: the stomach.
05/10/2018Many people have damaged or suboptimally functioning lungs. An accurate diagnosis and subsequent treatment are vital to protect this life-sustaining organ. Modern imaging solutions help physicians and patients understand what happens inside the lungs.
01/10/2018A look inside the lungs is a time-consuming process. To identify the boundaries of the respiratory organ from surrounding other organs, tissues, and structures requires between 200 and 500 computed tomographic images and subsequent manual markings – an elaborate process that can take up to six hours. An optimized computer program is now able to do this in only a few seconds.
01/10/2018Thanks to various imaging supplies, it is possible to make the inside of the body accessible for diagnostics, research and treatment. The lung, one of the most important human organs for survival, is also examined in this way. In our Topic of the Month, we looked at how doctors are getting a closer look at the lung, how the procedures differ, and which ones will be available in the near future.
01/10/2018Lung cancer is one of the most common and deadliest cancers. The symptoms tend to be non-specific, often causing its detection to be too late. Currently, there is no comprehensive screening. This could change with the use of low-dose CT scans. It should be noted that this is not just an issue of technical feasibility. A screening test must also make sense from a health policy perspective.
03/09/2018In a Smart Hospital, all devices are designed to be connected and integrated, thus increasing efficiency and reducing time loss – at least, that is how things are meant to work in theory. In reality, there are still countless vendor-specific point solutions that cannot be integrated. That's why there is a need for solutions that bridge the gap between the different applications and formats.
08/08/2018Some solutions are simple, though not necessarily obvious. The WAKE-UP study, which included 70 participating European stroke centers, has now studied a relatively simple procedure to manage the acute care of stroke patients and avoid potential long-term effects. Best of all, it is available wherever MRI is offered.
01/08/2018For years, medicine has been exploring AI techniques aimed at easing physician workload. While computers may not have the medical expertise and skills obtained through years of study, they can recognize patterns and specific features in datasets and draw deductions.
23/07/2018Every year, more than 250,000 patients worldwide receive heart valve implants. Children require repeated replacement surgery because their bodies are still growing, the prosthetic heart valves are not. Regenerative heart valves solve this problem. Until now, we have only been able to monitor how these living implants develop in the body after the fact. Computer models now make this predictable.
22/06/2018A drop of blood provides a lot of valuable information. However, it takes several hours to analyze the blood of a patient and make a diagnosis. This takes away a lot of time that's crucial for treatment. A new method intends to considerably speed up this process by testing the cells in the blood in terms of their deformability and immune response.
02/05/2018X-rays for diagnostic imaging and therapy evaluation are still the norm in orthopedics. Meanwhile, patients who frequently need X-rays are repeatedly exposed to radiation. That's why the University Hospital RWTH Aachen uses and develops methods that are not just radiation-free but can also capture motions.
08/03/2018Automation makes work life easier in many ways but is it also a solution for analyzing medical images? Is a computer actually reliable enough to assist in the medical decision making process? Researchers in Landshut examine how machine learning algorithms can work more reliably and support radiologists.
08/02/2018When body tissue is reconnected during a tumor operation in the gastrointestinal tract, surgeons need information about the current state of these so-called anastomoses. The new, non-invasive hyperspectral imaging technology now makes it possible to measure the crucial parameters during surgery and thereby increase surgical precision.
04/01/2018The position and alignment of surgical tools in the patient’s body must always be kept in view during the operation process to guarantee success and safety. With fine sensors at the tip of the instruments and an electromagnetic signal, Fiagon's electromagnetic navigation systems accurately reproduce their position in the body.
04/01/2018While it is commonplace for operating room staff to work together as a team, the collaboration of operating room systems does not always work so well – many devices are still separated from one another, causing the OR processes to be prone to mistakes. The same applies to surgical navigation technologies that represent the interface between imaging, the surgeon and therapeutic devices.
04/01/2018Imaging, navigation, integration – these are terms that describe the modern operating room. All of these components play a key role in accurate surgical procedures. They are integrated into surgical navigation systems, which make complicated medical surgeries considerably safer.
23/10/2017According to the WHO, 300 million people throughout the world are affected by lymphedema. This condition occurs when fluid that flows between cells is no longer transported back into the blood circulation and accumulates in the skin. Triggers can be surgeries, injuries or genetic defects for example. A new microscopy technique could now also indicate the causes.
01/09/2017There are many causes of myocarditis or inflammation of the heart muscle. Oftentimes, the culprits are viruses or bacteria and sometimes even an acute heart attack. Regardless of the cause, it creates a challenge for cardiologists: a diagnosis tends to be only nonspecific without a biopsy. A cardiac MRI and molecular imaging promise to provide assistance.
01/09/2017Coronary heart disease (CHD) can cause heart arrhythmia, heart insufficiency or heart attack. All the more important is an early, reliable diagnosis that helps to treat it and to reduce risk factors. But what is the best method for diagnosis? A recent study found that functional imaging methods can often spare patients the trouble and risks of a coronary angiography.
01/09/2017Many people are affected by heart disease today because - among other reasons- our modern unhealthy lifestyle is taking a toll on our hearts. A reliable diagnosis and treatment are crucial for patients with heart disease since all other organs depend on the pumping of our vital organ. Modern imaging techniques are a key to understanding the heart.
22/08/2017Physics has always supported medical science, especially when it comes to practical implementation. Now physicists and health professionals join in collaborative research at an interdisciplinary Center in Erlangen and incorporate fundamental principles of theoretical physics in their studies of diseases.
10/07/2017Radiation therapies are an essential component of today’s oncology because they enable the treatment of localized tumors. Yet they have one major drawback: radiation damages not just tumor cells but also healthy tissue. One solution to solve this problem could be proton minibeam therapy, which uses finely focused beams.
03/07/2017The scalpel is considered the classic surgical instrument and as such, has remained unchanged for quite some time. However, today’s technology opens up a world of new possibilities for cutting tissue. Next to high-frequency electrosurgical scalpels that work with electric power, surgeons also use a variety of different lasers. They promise great usability and better treatment.
03/07/2017Precision work is absolutely essential in eye surgery since the surgical site is very minute and sensitive. This is why eye surgeons have been using lasers for years. Femtosecond lasers are especially well suited to serve this purpose because they are able to cut tissue with great precision and little energy, which prevents unwanted side effects of surgery.
24/04/2017Liver cancer is the fifth most common malignant tumor in the world. The tumor can be removed through surgery or by utilizing thermal ablation techniques. If a treatment with conservative methods is no longer possible, there is an alternative: irreversible electroporation (IRE). The effectiveness of this method was now confirmed by a clinical study.
03/04/2017Instant treatment is absolute vital for patients developing sepsis. Providing a specific therapy early on is key. To manage this the pathogenic organisms need to be identified accurately. But a fungal sepsis can still be a hard nut to crack.
08/03/2017Pneumonia is the most frequent respiratory disease in children and can even cause death. That is why it is extremely important to make an accurate diagnosis as quickly as possible. If this requires imaging tests, normally X-rays are taken. But there is an alternative: ultrasound.
21/12/2016Within the scope of the VIRUSCAN project that is funded by the Horizon 2020 Research and Innovation Program of the European Union, Dr. Charlotte Uetrecht from Hamburg/Germany investigates individual viruses to be able to later identify them on a nanospring structure. MEDICA.de wanted to know: how does this work?
08/12/2016Watching millions of neurons in the brain interacting with each other – for a long time this was possible only to a limited extent. The current techniques can visualize only superficial layers or the imaging they use is too slow. But now, Prof Daniel Razansky and his team have found a new method to visualize the brain activity – by using optoacoustics.
08/09/2016For many patients, the start of hemodialysis marks the lifelong dependency on needing their blood purified. But before they can actually begin treatments, a blood vessel in the patient's arm needs to be enlarged to where it can move enough blood and withstand being connected to the dialysis machine several times per week.
01/09/2016Monitoring individual results during surgery with an angiography system? This is already an option in approximately 200 hospitals in Germany. Thanks to intraoperative imaging, major medical procedures can be replaced by minimally invasive surgery because physicians are able to monitor the results immediately. This is gentler on patients and decreases the number of subsequent revision surgeries.
01/09/2016Patients take center stage during surgery. Their treatment should be as gentle and effective as possible, which is why there is a trend towards minimally invasive surgery (MIS). But minimal procedures require better supporting technologies. The hybrid operating room combines surgery and imaging systems and increasingly replaces conventional open surgery approaches with MIS.
01/09/2016When it comes to the future of medicine, we often ponder how we would like to be treated. On the other hand, there is the issue of how physicians would like to treat their patients. The surgical procedures are determined by the technology that doctors are surrounded by. That’s why technology development also needs to be adapted to the needs of surgeons in the operating room of the future.
22/08/2016A beautiful field of flowers, a trip to the beach or a visit to the zoo. Children can experience all of these at the Clinical Center Dortmund in a 270- degree projection on the wall. The Center created a space that is designed to help its little patients overcome their fear of MRI scans.
02/05/2016Heart failure or cardiac insufficiency presents an extra strain on patients because it severally limits everyday performance and deprives them of energy. Due to their intense need for movement, children are particularly strongly affected. However, the disease is frequently not detected until the physical performance is already declining. An early diagnosis could prevent this.
01/03/2016Fortunately, only a handful of newborns are affected by them, though this determines if not the rest of their lives then, at least, the first few years of affected children: congenital heart defects. After the necessary surgeries, the small patients repeatedly need to return for checkups. Until now, these were conducted using MRI scans. 4D ultrasound can be an alternative.
01/03/2016Every little thing can be a matter of life or death for premature babies. That is why the right diagnosis plays an extremely important role. This includes examining infants with an MRI scan. Until now, sliding premature babies into an MRI scanner without an incubator was only possible to a limited degree. Now this problem could be solved.
02/11/2015Performing surgery in a hybrid operating room is meant to be a relief for the staff and offer patients new options for treatment. What is actually so different about this hybrid operating room, what can you expect and what should you keep in mind during the planning process?
01/10/2015It is a portmanteau, a mixture of two words. This way it saves us time and trouble while speaking because the human speech apparatus is lazy. And it describes a mixture of procedures: the combination of two procedures that would normally be separate in medicine. We are talking about theranostics.
01/10/2015A proper diagnosis is a part of great therapy. However, it can also be beneficial to be able to quickly respond to changes during a treatment. One example of this is the treatment of uterine myomas. Female patients at the University Hospital Bonn are treated using so-called high-intensity focused ultrasound, HIFU in short. Prof. Holger Strunk explains this procedure.
01/09/2015They can be seen everywhere: at the wrists, in the ear, clipped to the belt. Wearables are small technical assistants who are built to collect and partially also to analyze data. Some of them collect measurable health data, others "only" count their user’s steps or measure the surrounding UV radiation. The fact is, however, that wearables are en vogue and are used for many different cases.
03/08/2015Endoradiotherapy can be very unpleasant for cancer patients, since it does not only harm tumor cells, but also healthy ones. Sometimes, patients even need to stop therapy because of the side effects. Physicians and researchers are thus continuously searching for ways to transport radiopharmaceuticals directly and exclusively to their target.
03/08/2015Nuclear medicine physicians use so-called gamma cameras for myocardial perfusion scintigraphy. The devices record radioactive substances that are injected into the patient and show changes in the heart muscle (myocardium). Now a new gamma camera is able to record images faster and by using much less radiation.
03/08/2015Malignant tumors can be fought with X-rays – usually with radiation therapy from outside the body. Nuclear medicine physicians can also accomplish this inside the body with radioactive materials, called radiopharmaceuticals. They also offer big benefits for clinical diagnostics as long as a specific target can be assigned to them.
04/05/2015Whether it is a mammogram, colonoscopy or a skin cancer screening – after a certain age, we are subject to various early cancer detection screenings. Yet many of us don’t know that these screening tests are also associated with risks. This is something what Dr. Sylvia Sänger from the University Medical Center Hamburg-Eppendorf discovered in a study.
01/10/2014On November 10, 2014, astronaut Alexander Gerst will return to Earth from the International Space Station (ISS). He is not just anxiously expected by his family, but also by Dr. Anna-Maria Liphardt from the Institute of Biomechanics and Orthopedics at the German Sport University Cologne
01/10/2014Herniated discs can have very different effects: some cause no discomfort and are only discovered by accident; others can cause paralysis or cause patients to be in great pain. For the most part, these problems develop suddenly after an awkward movement – at least that is what patients report.
02/06/2014Sudden deaths of football players make headlines time after time: competitive athletes who are the idols of many people die just when they are on the playing field and in the limelight. Congenital heart defects often cause their death. Sports physicians and FIFA now plan to ascertain data that can help improve preventive examinations in competitive football.
04/03/2014Prenatal care, cancer check-up, vascular examinations – sonography is versatile, provides reliable imaging to physicians and does not tax patients with radiation. It is comprehensively available, from doctor’s office to university medical center. A sound continuing education of sonography users is essential for good diagnostics, also since different devices have different strong points.
03/02/2014Shortening a time-consuming procedure from four hours to five minutes and automate it at the same time sounds like a dream come true for employees in all fields and industry sectors. This dream could soon become a reality for radiologists. Software could take away the tedious processing of CT images, which is required before cancer radiation therapy.
03/02/2014Radiologists usually do their work after oncologists when it comes to cancer treatment. Yet modern radiology also provides treatments at this point. MEDICA.de spoke with Professor Stefan Schönberg, Director of the Institute of Clinical Radiology and Nuclear Medicine at the University Medical Center Mannheim, Germany, about the use of a new computer tomograph and its benefits for patients.