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Image: Visualization of a radioactive preparation that docks onto blood cells in a bloodstream; Copyright: B. Schröder/HZDR

B. Schröder/HZDR

Cancer: new theranostic for imaging and treatment

01.06.2023

Thanks to the radiation they emit, radioactive compounds are suited both to imaging and treating cancers. By appropriately combining them in novel, so-called radionuclide theranostics, both applications can be dovetailed.
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Image: Two men and a woman in a doctor's coat: the woman is holding a map of the world and the two men are pointing to Germany and Uzbekistan with a pen; Copyright: Karin Kaiser / MHH

Karin Kaiser / MHH

With ultrasound against liver cancer

24.05.2023

The Hannover Medical School (MHH) enters into a clinic partnership with Uzbekistan and supports with a training program for sonography diagnostics of hepatocellular carcinoma (HCC).
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Image: A computer that evaluates stool samples using bioinformatic methods; Copyright: Anna Schroll/Leibniz-HKI

Anna Schroll/Leibniz-HKI

Model shows intestinal bacteria influence growth of fungi

22.05.2023

The bacteria present in the intestine provide information about the quantities of fungi of the potentially disease-causing Candida genus.
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Image: A man in a gray jacket and white shirt, Miroslaw Bober, smiles at the camera; Copyright: University of Surrey

University of Surrey

UK AI world leader in identifying location and expression of proteins

18.05.2023

A new advanced artificial intelligence (AI) system has shown world-leading accuracy and speed in identifying protein patterns within individual cells.
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Image: Microscopic image of bone-marrow cells of a multiple myeloma patient.; Copyright: Berend Snijder Lab / ETH Zurich

Berend Snijder Lab / ETH Zurich

How to fight blood cancer more effectively

05.05.2023

Despite approved treatments being available, multiple myeloma remains incurable. But researchers at ETH Zurich and University Hospital Zurich set out to improve treatment outcomes by testing hundreds of existing therapeutics outside the body to predict their effectiveness.
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Image: 3D render of the tibias treated with the current clinical treatment option chemotherapeutics or treated with chemotherapeutics plus gene therapy; Copyright: UCD Research and Innovation

UCD Research and Innovation

Novel combination of therapies may provide new treatment option for bone cancer

03.05.2023

New research has identified a potential therapeutic target and developed a unique delivery system to treat osteosarcoma, a bone cancer that primarily affects children and adolescents.
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Image: Medical samples are treated with a plasma pen; Copyright: INP

INP

Plasma against precancerous skin lesions: EU funds international doctoral candidates network

24.04.2023

Under the leadership of the Leibniz Institute for Plasma Science and Technology (INP), the international doctoral candidates network PlasmACT is investigating the use of medical gas plasma technology as a treatment method.
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Image: Schematic illustration: The proposed robotic bronchoscope system for navigation-assisted intervention; Copyright: Cyborg and Bionic Systems

Cyborg and Bionic Systems

Novel robotic bronchoscope system for navigation and biopsy of pulmonary lesions

19.04.2023

A novel robotic bronchoscope system can non-intrusively access the area of interest within the lung for minimally invasive pulmonary lesions sampling, the gold standard of lung cancer diagnoses.
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Image: Johannes Karges smiles for the camera in a light blue shirt and dark blue jacket. In the background is a green area; Copyright: RUB, Marquard

RUB, Marquard

Ultrasound activates anticancer agent

14.04.2023

Chemotherapy treatments produce strong side effects. A new agent that accumulates in the tumour tissue and is activated there by ultrasound waves does not have this problem.
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Image: Dr Ioana Slabu and Benedict Bauer with the nanomodified stent fot he camera; Copyright: Peter Winandy

Peter Winandy

Novel technology for hollow organ tumour therapy

10.04.2023

Ioana Slabu from the Institute of Applied Medical Technology and Benedict Bauer from the Institut für Textiltechnik of RWTH Aachen University have developed a novel technology for the therapy of hollow organ tumours, which was awarded second place in the RWTH Innovation Award.
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Image: Three men and a woman in white lab coats pose for the camera in a laboratory; Copyright: Universidad de Barcelona

Universidad de Barcelona

Microfluidics physics-based device to predict cancer therapy response

06.04.2023

A team of experts has designed a microfluidic device called microfluidic dynamic BH3 profiling (μDBP) that predicts the effectiveness of cancer treatment quickly and automatically.
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Image: ENT doctor or dentist with a medical instrument examining the oral cavity; Copyright: YuriArcursPeopleimages

ONWARD Medical NV

PANDORA test could pave the way for better oral cancer detection

06.04.2023

Surrey scientists have developed a proof-of-concept test called PANDORA that was shown to be over 92% accurate at identifying patients with oral squamous cell carcinoma (OSCC). The test was also shown to be more than 80% accurate at identifying patients with pre-cancer or oral epithelial dysplasia (OED).
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Image: Study co-authors in white coats (from left) Caleb Bashor, Antonios Mikos and Letitia Chim; Copyright: Gustavo Raskosky/Rice University

Gustavo Raskosky/Rice University

Upgraded tumor model optimizes search for cancer therapies

27.03.2023

Rice University researchers developed an upgraded tumor model that houses osteosarcoma cells beside immune cells known as macrophages inside a three-dimensional structure engineered to mimic bone. Using the model, bioengineer Antonios Mikos and collaborators found that the body’s immune response can make tumor cells more resistant to chemotherapy.
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Image: Close-up of a pregnancy belly, the woman is holding her hand on her belly; Copyright: Karin Kaiser/MHH.

Karin Kaiser/MHH.

Better care for pregnant women with precancerous cervical cancer

23.03.2023

Preliminary stages of cervical cancer occur mainly in women between 25 and 35 years of age. The main risk factor for developing cervical cancer is the human papillomavirus (HPV). Surgery is the treatment of choice.
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Image: A woman with blond hair in a white coat sits in a laboratory and works with Petri dishes; Copyright: University of the West of Scotland

University of the West of Scotland

Radiology: Research could improve cancer treatment

22.03.2023

UWS School of Computing Engineering and Physical Sciences are developing breakthrough investigations into advanced radiation treatment technique, after receiving funding from Cancer Research UK RadNet – the charity's radiation research network.
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Image: Close-up of a female hand holding the orange ribbon symbolizing the fight against leukemia; Copyright: JoPanwatD

JoPanwatD

AI finds targets for CAR-T cell therapy against acute myeloid leukemia

20.03.2023

Unlike other forms of blood cancer, acute myeloid leukemia (AML) cannot currently be treated with CAR-T cell immunotherapy. The reason is that specific molecular targets with which certain immune cells could specifically target AML cells are lacking, which would permit the immune system to attack cancer.
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Image: Closeup of ultrasound examination of abdominal cavity, stomach and heart with sonography sensor; Copyright: Natabuena

Natabuena

Ultrasound method could lead to easier disease diagnosis in body tissue

17.03.2023

A new ultrasound method that can measure the level of tension in human tissue for the first time - a key indicator of disease - has been developed by researchers from the University of Sheffield.
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Image: Medical research Close-up of a microplate; Copyright: manjurulhaque

manjurulhaque

RIANA: Viennese start-up develops novel, precise anti-cancer drugs

14.03.2023

The technological basis is a proprietary platform technology for the discovery of drugs that target cancer-causing protein-protein interactions (PPIs).
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Image: Microscopic image: Mouse lymph nodes with colored fluorescent markers; Copyright: AG Hoelzel/UKB

AG Hoelzel/UKB

Artificial intelligence to help tumor immunology

09.03.2023

Developing methods to predict the nature of the tumor microenvironment is the goal of researchers from the Clusters of Excellence ImmunoSensation2 and the Hausdorff Center for Mathematics (HCM) led by Prof. Kevin Thurley at the University of Bonn.
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Image: Two men in white laboratory clothing are working on new quantum light modules; Copyright: FBH/P. Immerz

FBH/P. Immerz

Entangled photon pairs to help fighting cancer

06.03.2023

The recently launched QEED project aims to significantly reduce measurement time in clinical cancer diagnostics by developing a spectrally resolved imaging technique based on entangled photon pairs. FBH scientists will develop the required diode lasers and quantum light modules.
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Image: Two men and a woman stand in front of a building and smile for the camera; Copyright: RUB, Marquard

RUB, Marquard

AI with infrared imaging enables precise colon cancer diagnostics

23.02.2023

Researchers at the Centre for Protein Diagnostics PRODI at Ruhr University Bochum, Germany, are using artificial intelligence in combination with infrared imaging to optimally tailor colon cancer therapy to individual patients.
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Image: Dr Anke Katharina Bergmann in a white coat, holding a tablet, is standing in front of a virtual map of Europe; Copyright: Karin Kaiser / MHH, Freepik.com

Karin Kaiser / MHH, Freepik.com

MHH leads EU large-scale project for personalized cancer care

26.01.2023

CAN.HEAL aims to expand the available innovations in cancer prevention, diagnosis and treatment in the Member States in order to improve care for all patients in the EU. The project focuses on measures of personalized medicine. Genomics is an important cornerstone for this.
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Image: Three men poses for the camera, Dr Chiang Chi-leung and Professor Albert Chan Chi-yan. (Right) patient Mr Wan Ying-keung.; Copyright: The University of Hong Kong

The University of Hong Kong

'Reduce and Remove': new treatment strategy for locally advanced liver cancer

19.01.2023

A pioneering phase II clinical study on tri-modality therapy (START-FIT), conducted by the Department of Surgery and Department of Clinical Oncology, School of Clinical Medicine, LKS Faculty of Medicine of the University of Hong Kong (HKUMed), has found that nearly 50% of patients with inoperable locally advanced liver cancer, can be cured through such an innovative approach.
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Image: Representation of a uterus as a hologram. The hologram hovers over two cupped hands; Copyright: Medical University of Vienna

Medical University of Vienna

Locally advanced cervical cancer: Better odds using personalized brachytherapy

17.01.2023

For the first time, a study conducted by a research group at the Comprehensive Cancer Centre Vienna of MedUni Vienna and Vienna General Hospital using data from the multicentre EMBRACE-I trial demonstrated the superiority of a targeted approach in brachytherapy.
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Image: Two men and two women are standing in a laboratory and examining a small apparatus (microphysiological system); Copyright: Amac Garbe/Fraunhofer IWS

Amac Garbe/Fraunhofer IWS

Radioactive substances fight cancer in the mini-lab

13.01.2023

Two Dresden research institutes want to reduce the number of animal experiments in radiopharmaceutical research with a new idea.
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Image: Two doctors in scrubs look at a screen during an AI-assisted colonoscopy; Copyright: Universitätsklinikum Bonn (UKB)

Universitätsklinikum Bonn (UKB)

AI improves colorectal cancer screening in Lynch syndrome

10.01.2023

Researchers at the National Center for Hereditary Tumor Diseases (NZET) at Bonn University Hospital (UKB) have now found that artificial intelligence (AI) can improve the effectiveness of colonoscopy in the presence of Lynch syndrome.
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Image: Small moldecules - illustration in orange; Copyright: Aalto University

Aalto University

Gaining unprecedented view of small molecules by machine learning

06.01.2023

A new tool to identify small molecules offers benefits for diagnostics, drug discovery and fundamental research. A new machine learning model will help scientists identify small molecules, with applications in medicine, drug discovery and environmental chemistry.
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Image: Oncologist looking at patients x-ray photos and making notes in red notebook; Copyright: sofiiashunkina

sofiiashunkina

Complete package for minimally invasive tumor therapy

04.01.2023

License agreement and joint development: Fraunhofer MEVIS commences cooperation with Israeli partner for worldwide use of innovative software technology in ultrasound-aided tumor ablation.
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Image: Scientist works with medical test tube to analyze green liquid; Copyright: DC_Studio

DC_Studio

Diagnosing breast cancer through liquid biopsy

22.09.2022

Breast cancer diagnosis usually includes invasive testing with tissue biopsies. The samples have to be extracted from the cancerous tissue or cells. To make the process easier on the patients, the project LIBIMEDOTS is currently developing a different approach with liquid biopsy technology.
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Image: Thierry Nordmann (left) & Lisa Schweizer are standing in the lab, each with a pipette in hand and a microtiter plate in front of them; Copyright: Susanne Vondenbusch-Teetz, MPI for Biochemistry

Susanne Vondenbusch-Teetz, MPI for Biochemistry

Deep Visual Proteomics: tracking down cancer

08.09.2022

Proteins are frequently called the building blocks of life because they are found everywhere, including in our cells. This makes them an important factor when it comes to diseases. As a result, mapping the protein landscape can be a crucial ally in the fight against diseases. Now, a German-Danish team has developed a method that provides researchers with unprecedented insights into cancer.
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Image: Two drops of water on a screen that shows a pattern of colored bars; Copyright: ktsimage

ktsimage

Big Data in genetics: reaching diagnosis through heaps of data

01.08.2022

Most laboratory tests only produce small amounts of data that are already sufficient for successful diagnosis. It becomes more difficult with genetic questions: whether it is about a genetic disease or the properties of tumors, there are large amounts of data that must be considered. Both research and medicine need help to identify the connections and patterns in the data to find a diagnosis.
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Image: Two men are sitting in front of a laptop computer and are talking about an image on the screen - Josch Konstantin Pauling, Nikolai Köhler; Copytight: LipiTUM

LipiTUM

MoSBi: Algorithm identifies disease subtypes

01.08.2022

Doctors have always used symptoms, imaging, and laboratory data to define and diagnose diseases, but at times it is simply not enough: while patients may have the same illness, it may exhibit different changes at the molecular level. A team from the Technical University of Munich has developed the so-called MoSBi algorithm and makes it available to researchers to identify molecular differences.
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Image: Two male researchers analyzing data sets on a computer screen; Copyright: Felix Petermann | MDC

Felix Petermann | MDC

Project "ikarus" provides new insights for cancer research

01.08.2022

Artificial intelligence (AI) is about to become a game changer, especially in diagnostics. However, there are still limits to the use of AI. Dr. Altuna Akalin had to recognize this as well. The head of the Max Delbrück Center's (MDC) technology platform for "Bioinformatics and Omics Data Science" developed "ikarus" with his team.
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Image: Professor Dr Peter Hillemanns and PD Dr Matthias Jentschke with the HPV self-tests; Copyright: Karin Kaiser/MHH

Karin Kaiser/MHH

Prevention of cervical cancer with HPV self-testing

28.10.2021

Cervical cancer is one of the most common diseases of the female reproductive organs. Human papilloma viruses are almost always responsible for cervical cancer and the corresponding precancerous lesions. As part of the statutory preventive medical check-up, women from the age of 20 can have a cell smear taken from the cervix once a year, the so-called Pap test, to detect cell changes.
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Image: Two surgeons are standing at the control console of an OR device; Copyright: Christian Morawe/Universitätsmedizin Magdeburg

Christian Morawe/Universitätsmedizin Magdeburg

Histotripsy: fighting tumors with microbubbles

08.09.2021

Focused ultrasound waves create microbubbles in a fluid – a phenomenon called cavitation. In a current study, this process is used to destroy liver tumors and metastases.
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Image: Four men next to a CT - Peter Brotchie, Dr. Ruwan Tennakoon, Prof. John Thangarajah, Dr. Mark Page; Copyright: St Vincent's Hospital Melbourne

St Vincent's Hospital Melbourne

New AI tech for early detection of prostate cancer

16.07.2021

Prostate cancer is the most diagnosed cancer and a leading cause of death by cancer in Australian men. Early detection is key to successful treatment, but men often dodge the doctor, avoiding diagnosis tests until it is too late.
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Image: Two small, angular-shaped, electrical devices that are held with tweezers; Copyright: Fraunhofer EMFT/Bernd Müller

Tumor therapy: drug delivery pump instead of injection

01.02.2021

Drugs always have undesired side effects. Cytostatics are powerful drugs used to treat cancer. They reach almost all cells in the body, killing healthy cells as well as cancer cells in the process. A targeted delivery to the specific cellular site would be a gentler treatment.
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Image: Artist’s rendering of small star-shaped machines between red blood cells; Copyright: PantherMedia/Michael Osterrieder

Autonomous medical devices: running well in your body

01.02.2021

In theory, autonomous medical technologies can be used in a diagnostic or therapeutic capacity inside the body under certain conditions. This may not sound like a new invention at first. After all, implantable cardioverter-defibrillators have monitored and fixed abnormal heart rhythm for many years.
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Image: Laboratory situation - Prof. Popp shows a young man a small object in his hand; Copyright: Leibniz-IPHT/Sven Döring

Leibniz-IPHT/Sven Döring

Tumor excision: triple imaging for unique diagnostics

08.08.2019

After their tumor has been removed, some patients have to return to the hospital to undergo surgery again. That's because the tumor was not precisely identified and was subsequently not completely removed. That's both an ethical and financial dilemma. A new surgery-adjacent procedure is designed to rapidly and accurately detect tumors.
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Image: Preview picture of video

Functional Imaging: The puls of modern oncology

17.06.2019

Medical imaging techniques have developed considerably in recent decades. In addition to morphological imaging techniques more and more functional imaging techniques are used in oncology that can continously record the functions of specific organs locally and regionally in real time. These are groundbreaking for diagnostics, therapies and preoperative preparations.
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Photo: Preview picture of video

Where imaging and radiation meet – Radiotherapy with the MR-Linac

13.02.2019

In conventional radiotherapy, the tumor is first localized using CT and MRT images in order to calculate the irradiated areas. The major drawback in this case: the subsequent radiation only shows bone structures in the body but not the tumor itself. As a result, the radiated area is often larger than necessary. In our video you will learn how the MR-Linac can be used for more precise radiotherapy.
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