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Camouflaged nanoparticles deliver killer protein to cancer
A biomimetic nanosystem can deliver therapeutic proteins to selectively target cancerous tumors, according to a team of Penn State researchers. Using a protein toxin called gelonin from a plant found in the Himalayan mountains, the researchers caged the proteins in self-assembled metal-organic framework (MOF) nanoparticles to protect them from the body's immune system.
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Simulated procedures on virtual hearts
How can minimally invasive heart surgery be performed more effectively and more gently with the help of modern data and image processing algorithms? The Fraunhofer Institute for Medical Image Computing MEVIS in Bremen is working on this question - and has already achieved decisive success.
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Diabetes added to high risks for people with severe mental illness
People with severe mental illness are more than twice as likely to have Type 2 diabetes, with even higher risks among patients who are African American or Hispanic, according to a new study led by UCSF.
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How 'gatekeepers' to a cell's nucleus let genetic instructions pass through
New structural details emerge about one of the body's biggest protein assemblages, the nuclear pore complex.
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Blood formation: researchers engineer human bone marrow tissue
Researchers have developed an artificial tissue in which human blood stem cells remain functional for a prolonged period of time. Scientists from the University of Basel, University Hospital Basel, and ETH Zurich have reported their findings in the scientific journal PNAS.
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Study finds music therapy brings effective pain relief
New study from University Hospitals Connor Integrative Health Network published in the Journal of Music Therapy.
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Study offers new hope for the fight against genetically determined obesity
Around two to six per cent of all people with obesity develop obesity already in early childhood; it's in their genetic cards. Obesity-causal mutations in one of their "appetite genes" gives them a strong genetic predisposition for developing obesity, also called monogenic obesity. Their experience of hunger is overruling and their feeling of satiety limited.
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UA study links sleep loss with nighttime snacking
The study found poor sleep quality was associated with nighttime snacking and a high likelihood of craving junk food. The study also found that junk food cravings were associated with increased risk of obesity, diabetes and other health problems.
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Why do some sleep-deprived people experience worse cognitive functioning than others?
Penn study reveals that microRNAs predict differences in cognitive impairment in memory and attention after sleep deprivation.
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Immunoglobulin E as a promising new form of anti-cancer immunotherapy
If immunoglobulin E (IgE) antibodies are directed against harmless antigens such as pollen, the result can be an allergic reaction. However the original purpose of these IgE antibodies is to repel harmful exogenous substances rather than to trigger allergies.
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