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April 2012: The Lungs
Tumor-activated Protein Promotes Cancer Spread
( Source: MEDICA.de )
[15/05/2013] Researchers at the University of California report that cancers physically alter cells in the lymphatic system – a network of vessels that transports and stores immune cells throughout the body – to promote the spread of disease, a process called metastasis. Tumor-activated Protein Promotes Cancer Spread - Read more
Reversing Paralysis with Restorative Gel
( Source: MEDICA.de )
[14/05/2013] Some parts of the body, like the liver, can regenerate themselves after damage. But others, such as our nervous system, are considered either irreparable or slow to recover, leaving thousands with a lifetime of pain, limited mobility, or even paralysis. Reversing Paralysis with Restorative Gel - Read more
Stability for the Genome
( Source: MEDICA.de )
[10/05/2013] In cancer cells, the genome is often in a chaotic, unstable state. Now, a research group from the Würzburg Biocenter, Germany, found out which enzymes can stabilize DNA. Stability for the Genome - Read more
Cells Control Neuronal Connections
( Source: MEDICA.de )
[07/05/2013] Environment moulds behaviour - and not just that of people in society, but also at the microscopic level. This is because, for their function, neurons are dependent on the cell environment, the so-termed extracellular matrix. Cells Control Neuronal Connections - Read more
The Many Faces of the Bacterial Defense System
( Source: MEDICA.de )
[02/05/2013] Even bacteria have a kind of immune system they use to defend themselves against unwanted intruders – in their case, viruses. Scientists at the Helmholtz Center for Infection Research (HZI) in Braunschweig, Germany, were now able to show that this defense system is much more diverse than previously thought and that it comes in multiple versions. The Many Faces of the Bacterial Defense System - Read more
Conversion from Bad Fat to Good Fat
( Source: MEDICA.de )
[29/04/2013] Scientists from Swiss Federal Institute of Technology (ETH) Zurich have shown for the first time that brown and white fat cells in a living organism can be converted from one cell type to the other. Conversion from Bad Fat to Good Fat - Read more
High Treatment Costs Harming Patients
( Source: MEDICA.de )
[29/04/2013] The increasing cost of treatments for chronic myeloid leukemia (CML) in the United States has reached unsustainably high levels and may be leaving many patients under- or untreated because they cannot afford care, according to a study. High Treatment Costs Harming Patients - Read more
Detecting Autism from Brain Activity
( Source: MEDICA.de )
[19/04/2013] Neuroscientists from Case Western Reserve University School of Medicine and the University of Toronto have developed an efficient and reliable method of analyzing brain activity to detect autism in children. Detecting Autism from Brain Activity - Read more
How Alzheimer's Could Occur
( Source: MEDICA.de )
[12/04/2013] A new hypothesis has been developed by researchers from the Ruhr-Universität Bochum (RUB) on how Alzheimer's disease could occur. They analyzed the interaction of the proteins FE65 and BLM that regulate cell division. How Alzheimer's Could Occur - Read more
Moving Cells Holds Medical Promise
( Source: MEDICA.de )
[09/04/2013] Scientists at Washington University School of Medicine in St. Louis have shown they can coax cells to move toward a beam of light. The feat is a first step toward manipulating cells to control insulin secretion or heart rate using light. Moving Cells Holds Medical Promise - Read more
Capture of Circulating Tumor Cells
( Source: MEDICA.de )
[04/04/2013] A new system for isolating rare circulating tumor cells (CTCs) – living solid tumor cells found at low levels in the bloodstream – shows significant improvement over previously developed devices and does not require prior identification of tumor-specific target molecules. Capture of Circulating Tumor Cells - Read more
Development Depends On Grip
( Source: MEDICA.de )
[02/04/2013] Researchers have generated new insight on how a stem cell's environment influences its development: Whether human mesenchymal stem cells turn into fat or bone cells depends partially on how well they can "grip" the material they are growing in. Development Depends On Grip - Read more
New Nerve Cells Formed
( Source: MEDICA.de )
[28/03/2013] The field of cell therapy, which aims to form new cells in the body in order to cure disease, has taken another important step in the development towards new treatments. A new report from researchers at Lund University in Sweden shows that it is possible to re-programme other cells to become nerve cells, directly in the brain. New Nerve Cells Formed - Read more
The Fates of Individual T Cells
( Source: MEDICA.de )
[21/03/2013] By charting the differing fates of individual T cells, researchers have shown that previously unpredictable aspects of the adaptive immune response can be effectively modeled. The Fates of Individual T Cells - Read more
Macrophages Control Red Blood Cells
( Source: MEDICA.de )
[19/03/2013] Researchers at Albert Einstein College of Medicine and the Icahn School of Medicine at Mount Sinai have found that macrophages – white blood cells that play a key role in the immune response – also help to both produce and eliminate red blood cells. Macrophages Control Red Blood Cells - Read more
Laser Scalpel: Current Research Promises Gentle Surgery
( Source: MEDICA.de )
[13/03/2013] [Intro:] The Picosecond Infrared Laser (PIRL), which was developed at the University Medical Center Hamburg-Eppendorf (UKE), is intended to precisely cut down to the cell when used as a laser scalpel. During surgery, it avoids injuries to nerves or blood vessels and barely leaves any scarring.Laser Scalpel: Current Research Promises Gentle Surgery - Read more
Discovery of Destructive Protein
( Source: MEDICA.de )
[12/03/2013] Oxidative stress turns a protein that normally protects healthy cells into their executioner, according to a current study. This discovery could help scientists develop therapies to combat a host of conditions from stroke to Lou Gehrig's disease. Discovery of Destructive Protein - Read more
A Scanner for Hereditary Defects
( Source: MEDICA.de )
[25/01/2013] The body’s own proteins continually scour the genetic material for signs of damage. Researchers from the Institute of Veterinary Pharmacology and Toxicology at the University of Zurich see new possibilities in this damage recognition for improving cancer treatment in humans. A Scanner for Hereditary Defects - Read more
Oxygen Chamber Can Boost Brain Repair
( Source: MEDICA.de )
[24/01/2013] Doctor Shai Efrati of Tel Aviv University has found a way to restore a significant amount of neurological function in brain tissue thought to be chronically damaged — even years after initial injury. Oxygen Chamber Can Boost Brain Repair - Read more
Key to Proper Cell Division
( Source: MEDICA.de )
[22/01/2013] Studies led by cell biologist Thomas Maresca at the University of Massachusetts Amherst are revealing new details about a molecular surveillance system that helps detect and correct errors in cell division that can lead to cell death or human diseases. Key to Proper Cell Division - Read more
One Form of Neuron Turned into Another
( Source: MEDICA.de )
[21/01/2013] A new finding by Harvard stem cell biologists turns one of the basics of neurobiology on its head – demonstrating that it is possible to turn one type of already differentiated neuron into another within the brain. One Form of Neuron Turned into Another - Read more
Specific Protein Essential for Healthy Eyes
( Source: MEDICA.de )
[07/01/2013] Researchers have found that a specific protein is essential not only for maintaining a healthy retina in the eye, but also may have implications for understanding and possibly treating other conditions in the immune, reproductive, vascular and nervous systems and in various cancers. Specific Protein Essential for Healthy Eyes - Read more
Pair of Proteins Gets Brain Cells into Shape
( Source: MEDICA.de )
[21/12/2012] Scientists at the German Center for Neurodegenerative Diseases (DZNE) in Bonn have gained new insights into the early phase of the brain’s development. They identified two proteins that control the formation of cell protuberances. The typical ramifications through which nerve cells receive and forward signals ultimately originate from these outgrowths. Pair of Proteins Gets Brain Cells into Shape - Read more
”The project’s goal is to grow three-dimensional neural tissue“
( Source: MEDICA.de )
[21/12/2012] The international partners of the “3D-NeuroN” research project want to cultivate nerve tissue in three dimensions. German researchers are working on micro sensors with which they want to measure and evaluate electrical activity of neurons in three-dimensional cell cultures. ”The project’s goal is to grow three-dimensional neural tissue“ - Read more
Silent Stroke Can Cause Parkinson's Disease
( Source: MEDICA.de )
[20/12/2012] Scientists at The University of Manchester have for the first time identified why a patient who appears outwardly healthy may develop Parkinson's disease. Silent Stroke Can Cause Parkinson's Disease - Read more
Hybrid Tunnel Guides Severed Nerves
( Source: MEDICA.de )
[19/12/2012] Building a tunnel made up of both hard and soft materials to guide the reconnection of severed nerve endings may be the first step toward helping patients with extensive nerve trauma regain feeling and movement. Hybrid Tunnel Guides Severed Nerves - Read more
Heart Cells Become 'Biological Pacemakers'
( Source: MEDICA.de )
[17/12/2012] Cedars-Sinai Heart Institute researchers have reprogrammed ordinary heart cells to become exact replicas of highly specialized pacemaker cells by injecting a single gene (Tbx18) – a major step forward in the search for a biological therapy to correct erratic heartbeats. Heart Cells Become 'Biological Pacemakers' - Read more
Interfacing Biological and Artificial Systems
( Source: MEDICA.de )
[14/12/2012] In their recently published article researchers from the University of Tokyo describe how developments in synthesis techniques have liberated the polymer MPC’s potential for a huge range of medical and biological applications. Interfacing Biological and Artificial Systems - Read more
Ultrasound Can Stimulate Different Sensations
( Source: MEDICA.de )
[07/12/2012] A century after the world’s first ultrasonic detection device, Virginia Tech Carilion Research Institute scientists have provided the first neurophysiological evidence for something that researchers have long suspected: ultrasound applied to the periphery, such as the fingertips, can stimulate different sensory pathways leading to the brain. Ultrasound Can Stimulate Different Sensations - Read more
New Technique for Stem Cell Therapy
( Source: MEDICA.de )
[06/12/2012] Researchers from the University of Sheffield show a new method for producing membranes to help in the grafting of stem cells onto the eye, mimicking structural features of the eye itself. New Technique for Stem Cell Therapy - Read more
Precisely Engineering Tissue in 3D
( Source: MEDICA.de )
[03/12/2012] Borrowing from microfabrication techniques used in the semiconductor industry, MIT and Harvard Medical School (HMS) engineers have developed a simple and inexpensive way to create three-dimensional brain tissues in a lab dish. Precisely Engineering Tissue in 3D - Read more
“The body’s memory has an impact on neurological memory”
( Source: MEDICA.de )
[03/12/2012] Our behavior is reflected in our body. Poor nutrition or addictions affect body functions and leave their mark on the body’s memory. The neurological memory also works similarly: the nervous system stores the traces of the signaling pathways in cells and recalls them as required. “The body’s memory has an impact on neurological memory” - Read more
Traffic Cops of the Immune System
( Source: MEDICA.de )
[30/11/2012] A certain type of immune cell – the regulatory T cell, or Treg for short – is in charge of putting on the brakes on the immune response. In a way, this cell type might be considered the immune system’s traffic cop. Now, German scientists have looked into the origin of Tregs and uncovered a central role played by the protein IκBNS. Traffic Cops of the Immune System - Read more
Replication Machinery of Viruses Described
( Source: MEDICA.de )
[23/11/2012] Scientists at The Scripps Research Institute (TSRI) have made a major advance in understanding how flu viruses replicate within infected cells. Replication Machinery of Viruses Described - Read more
Step Forward in Regenerating and Repairing
( Source: MEDICA.de )
[23/11/2012] A team of researchers from the Institut de recherches cliniques de Montréal (IRCM), led by Doctor Frédéric Charron, recently uncovered a nerve cell’s internal clock, used during embryonic development. Step Forward in Regenerating and Repairing - Read more
Bright Light Reveals Location of Target Tissues
( Source: MEDICA.de )
[22/11/2012] Called BRIGHTs, tiny probes bind to biomarkers of disease and, when swept by an infrared laser, light up to reveal their location. The probes consist of gold nanoparticles covered with molecules called Raman reporters. Bright Light Reveals Location of Target Tissues - Read more
„We are very pleased with the fair. We had lots of visitors at our stand every day”
( Source: MEDICA.de )
[22/11/2012] CompuGroup Medical is one of the biggest exhibitors on MEDICA from the field of medical IT. In this year again, they have presented their products and solutions at a shared stand in hall 15. In the concluding interview from the last fair day, Volker Hess, Head of Marketing & Communications CER of CompuGroup Medical, told MEDICA.de that he is very pleased with the way the trade fair has gone. „We are very pleased with the fair. We had lots of visitors at our stand every day” - Read more
Hope for Regeneration Through Progenitor Cells
( Source: MEDICA.de )
[21/11/2012] A research team of the Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB has discovered cell surface markers that enable the identification and isolation of living functional cardiovascular progenitor cells (CPCs). Hope for Regeneration Through Progenitor Cells - Read more
Synthetic Cell Membrane Channels Made of DNA
( Source: MEDICA.de )
[21/11/2012] Physicists at the Technische Universitaet Muenchen (TUM) and the University of Michigan have shown that synthetic membrane channels can be constructed through "DNA nanotechnology." Synthetic Cell Membrane Channels Made of DNA - Read more
When Helper Cells Become Harmful
( Source: MEDICA.de )
[19/11/2012] In case of strokes, the immune system contributes to the brain injury. Scientists of the Universities of Würzburg and Münster, Germany, now show for the first time in which way certain T helper cells are involved in the process. When Helper Cells Become Harmful - Read more
Slim Electrode Cozies Up to Single Neurons
( Source: MEDICA.de )
[14/11/2012] A thin, flexible electrode developed at the University of Michigan is ten times smaller than the nearest competition and could make long-term measurements of neural activity practical at last. Slim Electrode Cozies Up to Single Neurons - Read more
A ‘Finger’ Pointing the Way to New Medication
( Source: MEDICA.de )
[12/11/2012] Researchers at the Helmholtz Centre for Infection Research (HZI) in Braunschweig, Germany, have discovered new drug leads that are efficient against resistant virus like HCV. A ‘Finger’ Pointing the Way to New Medication - Read more
Fat Molecule Ceramide May Factor in Muscle Loss
( Source: MEDICA.de )
[02/11/2012] A small study of older and younger men conducted at the Jean Mayer USDA Human Nutrition Research Center on Aging (USDA HNRCA) at Tufts University suggests that a build-up of a fat molecule known as ceramide might play a leading role in muscle deterioration in older adults. Fat Molecule Ceramide May Factor in Muscle Loss - Read more
Therapeutic Targets Identified
( Source: MEDICA.de )
[30/10/2012] New insight into the aggressive behavior of certain adult B-acute lymphoblastic leukemias has provided researchers with a potential new prognostic biomarker and a promising new therapeutic target. Therapeutic Targets Identified - Read more
Stimulating Brain Cells with Light
( Source: MEDICA.de )
[29/10/2012] Introducing a light-sensitive protein in transgenic nerve cells or transplanting nerve cells into the brains of laboratory animals to combat Parkinson’s disease – these events may sound like science fiction but they are soon to become a reality in Lund University in Sweden. Stimulating Brain Cells with Light - Read more
"Mechanically Active" DNA Material
( Source: MEDICA.de )
[25/10/2012] Artificial muscles and self-propelled goo may be the stuff of Hollywood fiction, but for scientists from University of California Santa Barbara (UCSB), the reality of it is not that far away. By blending their areas of expertise, the pair have created a dynamic gel made of DNA that mechanically responds to stimuli in much the same way that cells do. "Mechanically Active" DNA Material - Read more
Blood Stem Cells Versus Bone Marrow
( Source: MEDICA.de )
[22/10/2012] Doctor Claudio Anasetti of the Department of Blood & Marrow Transplant at Moffitt Cancer Center, and colleagues from 47 research sites conducted a two-year clinical trial comparing two-year survival probabilities for patients transplanted with peripheral blood stem cells or bone marrow stem cells from unrelated donors. Blood Stem Cells Versus Bone Marrow - Read more
New Findings About Mitchondrial Diseases
( Source: MEDICA.de )
[09/10/2012] Researchers from the Max Planck Institute for Biology of Aging discovered, how and when mitochondrial diseases are inherited, using a new model. This is decided when the future mother herself is still an embryo. New Findings About Mitchondrial Diseases - Read more
Nanoparticles Against Aging
( Source: MEDICA.de )
[05/10/2012] A team of Spanish scientists of the Asociación RUVID has developed an intelligent nanodevice that lays the foundations for the future development of new therapies against aging. The device consists of nanoparticles that can selectively release drugs in aged human cells. Nanoparticles Against Aging - Read more
How Immune Cells Defend Themselves Against HIV
( Source: MEDICA.de )
[27/09/2012] A team of scientists led by virologists Professor Oliver T. Fackler and Professor Oliver T. Keppler from Heidelberg University Hospital, Germany, have decoded a mechanism used by the human immune system to protect itself from HIV viruses. How Immune Cells Defend Themselves Against HIV - Read more
Double Assault on Tough Types of Leukemias
( Source: MEDICA.de )
[24/09/2012] Investigators at Northwestern University Feinberg School of Medicine have identified two promising therapies to treat patients with acute megakaryocytic leukemia (AMKL), a rare form of leukemia where the number of cases is expected to increase with the aging population. Double Assault on Tough Types of Leukemias - Read more
Puzzle of B-Cell Lymphoma Development Solved
( Source: MEDICA.de )
[24/09/2012] Doctor Dinis Pedro Calado and Doctor Klaus Rajewsky of the Max Delbrück Center (MDC) have identified subgroups of B cells in germinal centers in which the proto-oncogene Myc, a critical regulator of cellular proliferation, is highly activated. Puzzle of B-Cell Lymphoma Development Solved - Read more
“People take a reserved stance towards naturopathic procedures"
( Source: MEDICA.de )
[24/09/2012] When people talk about fasting, they often mean caloric restriction in terms of a dietary regimen. Yet medically supervised fasting is so much more than this. Fasting has a positive effect on the human body in many different ways and could provide new perspectives for chronically sick people in the future. What mechanisms are behind all this – what is psychology and what is scientifically proven? “People take a reserved stance towards naturopathic procedures" - Read more
Boosting Efficacy of Drugs
( Source: MEDICA.de )
[20/09/2012] Nanoparticles have shown great promise in the targeted delivery of drugs to cells, but researchers at the University of Georgia have refined the drug delivery process further by using nanoparticles to deliver drugs to a specific organelle within cells. Boosting Efficacy of Drugs - Read more
The Mystery of The Third Signal
( Source: MEDICA.de )
[18/09/2012] At least three protective mechanisms defend the lungs against erroneous attacks by the body's own immune system. This was discovered by the Immuneregulation research group of Professor Dunja Bruder at the Helmholtz Centre for Infection Research (HZI) in Braunschweig, Germany. The Mystery of The Third Signal - Read more
License for Self-destruction
( Source: MEDICA.de )
[07/09/2012] A research team of the University Medical Center Göttingen could now show that the Multiple Sclerosis-causing immune cells are programmed in the lung to be more motile and to efficiently break through blood vessel barriers. License for Self-destruction - Read more
Nanoparticles Reboot Blood Flow
( Source: MEDICA.de )
[27/08/2012] A nanoparticle developed at Rice University and tested in collaboration with Baylor College of Medicine (BCM) may bring great benefits to the emergency treatment of brain-injury victims, even those with mild injuries. Nanoparticles Reboot Blood Flow - Read more
Video Shows The Traffic Inside a Brain Cell
( Source: MEDICA.de )
[24/08/2012] Using bioluminescent proteins from a jellyfish, a team of scientists has lit up the inside of a neuron, capturing spectacular video footage that shows the movement of proteins throughout the cell. Video Shows The Traffic Inside a Brain Cell - Read more
Acute Stress Alters Control of Gene Activity
( Source: MEDICA.de )
[15/08/2012] Acute stress alters the methylation of the DNA and thus the activity of certain genes. This is reported by researchers at the Ruhr-Universität Bochum, Germany, together with colleagues from Basel, Trier and London for the first time. Acute Stress Alters Control of Gene Activity - Read more
New Method May Allow Personalized Clinical Trial
( Source: MEDICA.de )
[14/08/2012] An approach, developed by investigators at Vanderbilt-Ingram Cancer Center, shows that erlotinib – a targeted therapy that acts on a growth factor receptor mutated in some lung, brain and other cancers – does not simply kill tumor cells as was previously assumed. New Method May Allow Personalized Clinical Trial - Read more
White Blood Cells Mediate Insulin Resistance
( Source: MEDICA.de )
[07/08/2012] Researchers at the University of California, San Diego say neutrophils, an abundant type of white blood cell typically tasked with attacking bacteria and other foreign invaders, also plays an unexpected role in mediating insulin resistance – the central characteristic of type 2 diabetes, which afflicts an estimated 26 million Americans. White Blood Cells Mediate Insulin Resistance - Read more
Virus Throws a Wrench in The Immune System
( Source: MEDICA.de )
[17/07/2012] The cytomegalovirus (CMV) is a member of the herpes virus family. Although most people carry CMV for life, it hardly ever makes them sick. Researchers from the Helmholtz Centre for Infection Research and from the USA have now unveiled long term consequences of the on-going presence of CMV. Virus Throws a Wrench in The Immune System - Read more
Trafficking of Immune Cells
( Source: MEDICA.de )
[16/07/2012] Now, working in mice, surgeons and scientists at Washington University School of Medicine in St. Louis, have captured the first images of a beating heart at a resolution so detailed they can track individual immune cells swarming into the heart muscle, causing inflammation. Trafficking of Immune Cells - Read more
Recommendations of Federal Office of Public Health Reinforced
( Source: MEDICA.de )
[06/07/2012] Several clinical trials have looked at whether the number of hip fractures and the horrendous costs associated with them can be reduced by administering prophylactic vitamin D. The results have been inconsistent. Researchers working with Heike Bischoff-Ferrari from the Centre on Ageing and Mobility at Zurich University have now produced a new overview of the data. Recommendations of Federal Office of Public Health Reinforced - Read more
How Fat Regulates Cholesterol Absorption
( Source: MEDICA.de )
[28/06/2012] James Walters and his colleagues at the Carnegie Institution for Science are using zebrafish to better understand the cellular mechanisms of cholesterol processing and have discovered a surprising link between dietary fat and cholesterol absorption. How Fat Regulates Cholesterol Absorption - Read more
Following Oxygen
( Source: MEDICA.de )
[25/06/2012] How single cell organisms like bacteria manage to react to their environment is not yet completely understood. Together with colleagues from Japan, Doctor Samir El-Mashtoly from the Ruhr University Bochum, Germany, has gained new insights into the molecular interactions. Following Oxygen - Read more
Cause of Pain in the Treatment
( Source: MEDICA.de )
[21/06/2012] Apply the ointment, light on, light off – that is how easy it is to cure various forms of non-melanoma skin cancer. However, the majority of patients suffer severe pain during the so-termed photodynamic therapy. Why the treatment can be so painful has now been uncovered. Cause of Pain in the Treatment - Read more
How Many Cells Can Our Blood Tolerate?
( Source: MEDICA.de )
[15/06/2012] Bioinformaticians of Jena University calculated the optimal value of hematocrit with the help of Einstein‘s equation. How Many Cells Can Our Blood Tolerate? - Read more
"There is an enormous automation in laboratory techniques"
( Source: MEDICA.de )
[08/06/2012] The function of systems biology is to treat organs and biological organisms as a whole. In doing so, researchers among other things examine interactions and different aspects of the human cell. This still young discipline creates interfaces to biology, mathematics and physics to be able to understand regulatory processes for cells, tissues and organisms and thus get an integrated idea. "There is an enormous automation in laboratory techniques" - Read more
Cell Contents for Controlling Toxicity
( Source: MEDICA.de )
[08/06/2012] New research into the cell-damaging effects of Huntington's disease suggests a potentially new approach for identifying possible therapeutic targets for treating the nerve-destroying disorder. Cell Contents for Controlling Toxicity - Read more
Treating Drug-resistant Tumour Cells
( Source: MEDICA.de )
[05/06/2012] New research from the University of Wisconsin-Madison explains why the incurable brain cancer, glioblastoma multiforme (GBM), is highly resistant to current chemotherapies. Treating Drug-resistant Tumour Cells - Read more
New Technique Mimics the Brain
( Source: MEDICA.de )
[24/05/2012] A new technique that converts stem cells into brain cells has been developed by researchers at Lund University. The method is simpler, quicker and safer than previous research has shown and opens the doors to a shorter route to clinical cell transplants. New Technique Mimics the Brain - Read more
Rainbow of Light to Image Blood Cells
( Source: MEDICA.de )
[22/05/2012] Blood tests convey vital medical information, but the sight of a needle often causes anxiety and results take time. A new device developed by a team of researchers in Israel, however, can reveal much the same information as a traditional blood test in real-time, simply by shining a light through the skin. Rainbow of Light to Image Blood Cells - Read more
“We can convert skin cells into nerve cells more efficiently”
( Source: MEDICA.de )
[22/05/2012] Until now, curing neurological disorders has been a vision of the future. Scientists at the LIFE & BRAIN Centre in Bonn, Germany, however have come a bit closer to achieving this with a new procedure and are now able to convert skin cells into nerve cells. “We can convert skin cells into nerve cells more efficiently” - Read more
Fighting Bacteria's Strength in Numbers
( Source: MEDICA.de )
[21/05/2012] Scientists at The University of Nottingham have opened the way for more accurate research into new ways to fight dangerous bacterial infections by proving a long-held theory about how bacteria communicate with each other. Fighting Bacteria's Strength in Numbers - Read more
Growth Regulator mTORC2 Linked to Diabetes
( Source: MEDICA.de )
[15/05/2012] Scientists of the University of Basel show how inhibition of the protein mTOR signalling can impair carbohydrate metabolism and potentially lead to diabetes. Growth Regulator mTORC2 Linked to Diabetes - Read more
Glial Cells Pass on Metabolites to Neurons
( Source: MEDICA.de )
[11/05/2012] Klaus Armin and his research group from the Max Planck Institute of Experimental Medicine in Göttingen, Germany, have now discovered possible mechanisms by which these glial cells in the brain can support their associated axons and keep them alive in the long term. Glial Cells Pass on Metabolites to Neurons - Read more
”We are not limited to one active ingredient group or one active ingredient“
( Source: MEDICA.de )
[08/05/2012] Drugs that treat brain diseases such as Alzheimer’s disease or multiple sclerosis are most effective directly where they are needed – in the brain. Unfortunately, it is difficult to develop drugs that are capable of getting there specifically, since the so-called blood-brain barrier prevents this from happening. However, now a team led by Doctor Heiko Manninga succeeded in doing precisely that. ”We are not limited to one active ingredient group or one active ingredient“ - Read more
New Understanding of Alzheimer's Trigger
( Source: MEDICA.de )
[07/05/2012] A highly toxic beta-amyloid – a protein that exists in the brains of Alzheimer's disease victims – has been found to greatly increase the toxicity of other more common and less toxic beta-amyloids, serving as a possible "trigger" for the advent and development of Alzheimer's, researchers at the University of Virginia have discovered. New Understanding of Alzheimer's Trigger - Read more
Glycogen Accumulation in Neurons Causes Brain Damage
( Source: MEDICA.de )
[03/05/2012] Collaborative research by groups headed by scientists Joan J. Guinovart and Marco Milán at the Institute for Research in Biomedicine (IRB Barcelona) has revealed conclusive evidence about the harmful effects of the accumulation of glucose chains (glycogen) in fly and mouse neurons. Glycogen Accumulation in Neurons Causes Brain Damage - Read more
Foetal Membrane Transplantation Prevents Blindness
( Source: MEDICA.de )
[30/04/2012] Transplanting tissue from newborn foetal membranes prevents blindness in patients with a devastating disease called Stevens-Johnson syndrome, a Loyola University Medical Centre study has found. Foetal Membrane Transplantation Prevents Blindness - Read more
Pancreatic Tumours Depend on Oncogene Activity
( Source: MEDICA.de )
[27/04/2012] Researchers at Dana-Farber Cancer Institute have shown that advanced pancreatic cancers in mice cannot survive without continued expression of a mutant oncogene that "rewires" key metabolic pathways to fuel the cancer cells. Pancreatic Tumours Depend on Oncogene Activity - Read more
Brain-Machine Interface Moves a Paralysed Hand
( Source: MEDICA.de )
[23/04/2012] A new Northwestern Medicine brain-machine technology delivers messages from the brain directly to the muscles - bypassing the spinal cord - to enable voluntary and complex movement of a paralysed hand. The device could eventually be tested on, and perhaps aid, paralysed patients. Brain-Machine Interface Moves a Paralysed Hand - Read more
New Trigger for Alternate Reproduction Pathway
( Source: MEDICA.de )
[19/04/2012] A research team led by Children’s National Medical Centre has identified a trigger that causes latent Kaposi’s sarcoma-associated herpes virus (KSHV) to rapidly replicate itself. KSHV causes Kaposi’s sarcoma, primary effusion lymphoma, and other cancers that commonly affect immunocompromised patients, including those with AIDS. New Trigger for Alternate Reproduction Pathway - Read more
Unexpected Partnership Drives Immunity
( Source: MEDICA.de )
[16/04/2012] New research of Harvard Medical School (HMS) challenges a well-established theory about antiviral immunity and may lead to a new understanding of the best way to help protect those exposed to potentially lethal viruses, such as rabies. Unexpected Partnership Drives Immunity - Read more
Sequencing Technology Decodes DNA Folding Pattern
( Source: MEDICA.de )
[12/04/2012] Using a powerful DNA sequencing methodology, researchers at the Ludwig Institute for Cancer Research have now investigated the three-dimensional structure of DNA folds in the nucleus of a chromosome. The findings provide scientists with a greater understanding about the basic principles of DNA folding and its role in gene regulation. Sequencing Technology Decodes DNA Folding Pattern - Read more
Hot on the Trail of Metabolic Diseases and Resistance to Antibiotics
( Source: MEDICA.de )
[29/03/2012] Proteins belonging to the large and important family of ABC transporters have been associated with metabolic diseases and can cause resistance to antibiotics. Biochemists from the University of Zurich have succeeded in determining the atomic structure of a new ABC transporter. The insights gained could give rise to new therapies to treat multi-resistant bacteria, cystic fibrosis or gout. Hot on the Trail of Metabolic Diseases and Resistance to Antibiotics - Read more
Unlikely Cause of Atherosclerosis
( Source: MEDICA.de )
[29/03/2012] A number of studies have shown that excess insulin circulating in the bloodstream is a major independent risk factor for cardiovascular disease. However, a new study from Joslin Diabetes Centre finds that this condition, called hyperinsulinemia, is itself not a cause of atherosclerosis. Unlikely Cause of Atherosclerosis - Read more
Growth Rates of Lung Cancers Found
( Source: MEDICA.de )
[27/03/2012] According to the latest report from the International Early Lung Cancer Action Program (I-ELCAP), lung cancers diagnosed in annual repeat rounds of CT screening are similar — both in volume doubling time and cell-type distribution — to those found in clinical practice. Growth Rates of Lung Cancers Found - Read more
Novel Pathway for T-cell Activation in Leprosy
( Source: MEDICA.de )
[27/03/2012] University of California – Los Angeles researchers pinpointed a new mechanism that potently activates T-cells, the group of white blood cells that play a major role in fighting infections. The team specifically studied how dendritic cells, immune cells located at the site of infection, become more specialised to fight the leprosy pathogen known as Mycobacterium leprae. Novel Pathway for T-cell Activation in Leprosy - Read more
Somatic Stem Cells Obtained from Skin Cells
( Source: MEDICA.de )
[23/03/2012] Breaking new ground, scientists at the Max Planck Institute for Molecular Biomedicine in Münster, Germany, have succeeded in obtaining somatic stem cells from fully differentiated somatic cells. Stem cell researcher Hans Schöler and his team took skin cells from mice and have managed to induce the cells' differentiation into neuronal somatic stem cells. Somatic Stem Cells Obtained from Skin Cells - Read more
Bone Marrow Transplant Arrests Symptoms
( Source: MEDICA.de )
[20/03/2012] The Organisation Rett Syndrome Research Trust describes the results of using bone marrow transplant (BMT) to replace faulty immune system cells in models of Rett Syndrome. The procedure arrested many severe symptoms of the childhood disorder, including abnormal breathing and movement, and significantly extended the lifespan of Rett mouse models. Bone Marrow Transplant Arrests Symptoms - Read more
Influence of Nanoparticles on Nutrient Absorption
( Source: MEDICA.de )
[09/03/2012] Nanoparticles are everywhere. From cosmetics and clothes, to soda and snacks. But as versatile as they are, nanoparticles also have a downside, say researchers at Binghamton University and Cornell University. These tiny particles, even in low doses, could have a big impact on our long-term health. Influence of Nanoparticles on Nutrient Absorption - Read more
Tonsils Make T-Cells
( Source: MEDICA.de )
[07/03/2012] A new study provides evidence that a critical type of immune cell can develop in human tonsils. The cells, called T lymphocytes, or T cells, have been thought to develop only in the thymus, an organ of the immune system that sits on the heart. Tonsils Make T-Cells - Read more
Protein Identified that Can Lengthen Our Life
( Source: MEDICA.de )
[02/03/2012] Cells use various methods to break down and recycle worn-out components – autophagy is one of them. Karin Håberg of the Umeå University, Sweden, shows that the protein SNX18 is required for cells to be able to perform autophagy. Protein Identified that Can Lengthen Our Life - Read more
View on Causal Mechanism in ALS
( Source: MEDICA.de )
[01/03/2012] In a study Munich-based researchers refute a widely accepted hypothesis about a causative step in neurodegenerative conditions. These results deal specifically with animal models of human amyotrophic lateral sclerosis (ALS, aka Lou Gehrig's disease) but also raise questions for research on other neurodegenerative diseases, such as Alzheimer's or Huntington's disease. View on Causal Mechanism in ALS - Read more
How the Brain Communicates
( Source: MEDICA.de )
[29/02/2012] An important mechanism by which the human brain hemispheres communicate with each other has been discovered by a team of researchers from Berlin and the University of Bern. The findings provide new insights into nerve cell communication in the brain that could also play a role in stroke. How the Brain Communicates - Read more
How to Rescue the Immune System
( Source: MEDICA.de )
[28/02/2012] In a study Loyola researchers report on a promising new technique that potentially could turn immune system killer T cells into more effective weapons against infections and possibly cancer. How to Rescue the Immune System - Read more
Injectable Gel Could Repair Tissue
( Source: MEDICA.de )
[24/02/2012] University of California, San Diego researchers have developed a new injectable hydrogel that could be an effective and safe treatment for tissue damage caused by heart attacks. Injectable Gel Could Repair Tissue - Read more
”We can reduce the number of animal experiments“
( Source: MEDICA.de )
[22/02/2012] Animal experiments are a part of everyday life in medical research, yet they have been the subject of criticism for decades. Even though scientists all over the world are searching for alternative methods, the complexity of physical processes in the human body however makes this very difficult. ”We can reduce the number of animal experiments“ - Read more
Faulty Fat Sensor Implicated
( Source: MEDICA.de )
[21/02/2012] Defects in a protein that functions as a dietary fat sensor may be a cause of obesity and liver disease, according to a study led by researchers at Imperial College London. The findings highlight a promising target for new drugs to treat obesity and metabolic disorders. Faulty Fat Sensor Implicated - Read more
Pancreatic Hormone Linked with Severe Heart Disease in Obese
( Source: MEDICA.de )
[17/02/2012] Severe heart damage in people who are obese and diabetic is linked with a pancreatic hormone called amylin, University of California Davis researchers have found. In the failing hearts of patients who were obese and diabetic, the scientists discovered strings of proteins, small fibres and plaques made of amylin, the hormone that produces the feeling of being full after eating. Pancreatic Hormone Linked with Severe Heart Disease in Obese - Read more
Antibodies to Intracellular Cancer Antigens Enhance Immunity
( Source: MEDICA.de )
[15/02/2012] An international team of scientists in Japan, Switzerland, and the United States has confirmed that combining chemotherapy and immunotherapy in cancer treatment enhances the immune system's ability to find and eliminate cancer cells, even when the cancer-associated proteins targeted by the immune system are hidden behind the cancer cell membrane. Antibodies to Intracellular Cancer Antigens Enhance Immunity - Read more
Key to Taming Chronic Pain
( Source: MEDICA.de )
[15/02/2012] A team of researchers led by McGill neuroscientist Terence Coderre, who is also affiliated with the Research Institute of the McGill University Health Centre, has found the key to understanding how memories of pain are stored in the brain. More importantly, the researchers are also able to suggest how these memories can be erased, making it possible to ease chronic pain. Key to Taming Chronic Pain - Read more
Protein Protects Cells from HIV Infection
( Source: MEDICA.de )
[13/02/2012] A novel discovery by researchers at New York University Langone Medical Centre and colleagues reveals a mechanism by which the immune system tries to halt the spread of HIV. Harnessing this mechanism may open up new paths for therapeutic research aimed at slowing the virus' progression to AIDS. Protein Protects Cells from HIV Infection - Read more
Why the Middle Finger Has Such a Slow Connection
( Source: MEDICA.de )
[07/02/2012] Each part of the body has its own nerve cell area in the brain –we therefore have a map of our bodies in our heads. The functional significance of these maps is largely unclear. What effects they can have is now shown by Ruhr-Universität Bochum, Germany, neuroscientists through reaction time measurements combined with learning experiments and “computational modelling”. Why the Middle Finger Has Such a Slow Connection - Read more
Small Molecules at the Cell’s Membrane Enable Cell Movement
( Source: MEDICA.de )
[03/02/2012] Cell biologists at Johns Hopkins have identified key steps in how certain molecules alter a cell’s skeletal shape and drive the cell’s movement. Results of their research have implications for figuring out what triggers the metastatic spread of cancer cells and wound-healing. Small Molecules at the Cell’s Membrane Enable Cell Movement - Read more
Leukaemia Cells Are “Bad to the Bone”
( Source: MEDICA.de )
[30/01/2012] University of Rochester Medical Centre researchers have discovered new links between leukaemia cells and cells involved in bone formation, offering a fresh perspective on how the blood cancer progresses and raising the possibility that therapies for bone disorders could help in the treatment of leukaemia. Leukaemia Cells Are “Bad to the Bone” - Read more
Drug Kills Cancerous T-Cells While Sparing Normal Immunity
( Source: MEDICA.de )
[26/01/2012] Leukemic cutaneous T-cell lymphoma (L-CTCL) is a leukaemia arising from T-cells, a type of white blood cell. This cancer can involve the skin and other organs, and patients often die within three years. Researchers of Brigham and Women's Hospital (BWH) report a new study that low-dose Campath not only treats patients with L-CTCL but does so without increasing their risk of infections. Drug Kills Cancerous T-Cells While Sparing Normal Immunity - Read more
Entry Point for Hepatitis C Infection Identified
( Source: MEDICA.de )
[25/01/2012] A molecule embedded in the membrane of human liver cells that aids in cholesterol absorption also allows the entry of hepatitis C virus, the first step in hepatitis C infection, according to research at the University of Illinois at Chicago College of Medicine. Entry Point for Hepatitis C Infection Identified - Read more
New Understanding of Chronic Pain
( Source: MEDICA.de )
[23/01/2012] Millions of people worldwide suffer from a type of chronic pain called neuropathic pain, which is triggered by nerve damage. Precisely how this pain persists has been a mystery, and current treatments are largely ineffective. But a team led by scientists from The Scripps Research Institute, using a new approach known as metabolomics, has now discovered a major clue: dimethylsphingosine (DMS). New Understanding of Chronic Pain - Read more
Where Categories Live in the Brain
( Source: MEDICA.de )
[18/01/2012] Hundreds of times during a baseball game, the home plate umpire must instantaneously categorise a fast-moving pitch as a ball or a strike. In new research from the University of Chicago, scientists have pinpointed an area in the brain where these kinds of visual categories are encoded. Where Categories Live in the Brain - Read more
How Immune Cells Destroy Cancer Cells
( Source: MEDICA.de )
[17/01/2012] Doctor Kathleen Anders and Professor Thomas Blankenstein of the Max Delbrück Centre (MDC) Berlin-Buch and researchers of the Beckman Research Institute of the City of Hope Cancer Centre in Duarte, California, USA showed that drug-based cancer treatment and adoptive T cell therapy are both highly effective against large tumours. How Immune Cells Destroy Cancer Cells - Read more
Novel Way to Prevent Drug-Induced Liver Injury
( Source: MEDICA.de )
[17/01/2012] Rutgers University and Massachusetts General Hospital (MGH) investigators have developed a novel strategy to protect the liver from drug-induced injury and improve associated drug safety. Novel Way to Prevent Drug-Induced Liver Injury - Read more
Novel Approach to View Inner Workings of Viruses
( Source: MEDICA.de )
[13/01/2012] Since the discovery of the microscope, scientists have tried to visualise smaller and smaller structures to provide insights into the inner workings of human cells, bacteria and viruses. Now, researchers at the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) have developed a new way to see structures within viruses that were not clearly seen before. Novel Approach to View Inner Workings of Viruses - Read more
High Rates of Disability and Health Care
( Source: MEDICA.de )
[12/01/2012] Older patients with cirrhosis have significant functional disability, require twice the amount of informal care giving, and contribute added strain on the health care system, according to University of Michigan research. Given the increase in obesity and aging of those with hepatitis C (HCV), researchers expect the prevalence of cirrhosis to climb among older Americans. High Rates of Disability and Health Care - Read more
New Strategy to Deliver Chemotherapy to Cancer Cells
( Source: MEDICA.de )
[11/01/2012] Honing chemotherapy delivery to cancer cells is a challenge for many researchers. Getting the cancer cells to take the chemotherapy "bait" is a greater challenge. But perhaps such a challenge has not been met with greater success than by the nanotechnology research team of Brigham and Women's Hospital (BWH). New Strategy to Deliver Chemotherapy to Cancer Cells - Read more
New Test Spots Early Signs of Inherited Metabolic Disorders
( Source: MEDICA.de )
[09/01/2012] A team of scientists, led by researchers at the University of California, San Diego School of Medicine, have developed a simple, reliable test for identifying biomarkers for mucopolysaccharidoses (MPS), a group of inherited metabolic disorders that are currently diagnosed in patients only after symptoms have become serious and the damage possibly irreversible. New Test Spots Early Signs of Inherited Metabolic Disorders - Read more
Benefits of Statin Therapy May Extend Beyond Lowering Lipids
( Source: MEDICA.de )
[05/01/2012] A study led by researchers from the University of North Carolina at Chapel Hill School of Medicine, has identified a molecular pathway that leads to this abnormal blood clotting and turned it off using a popular class of cholesterol-lowering drugs, statins. Benefits of Statin Therapy May Extend Beyond Lowering Lipids - Read more
Fewer Animal Experiments Thanks to Nanosensors
( Source: MEDICA.de )
[04/01/2012] Experiments on animals have been the subject of criticism for decades. The number of tests involving laboratory animals has in fact gone up. Now, researchers of the Fraunhofer Research Institution for Modular Solid State Technologies EMFT in Munich, Germany have found an alternative approach: they hope sensor nanoparticles will reduce the need for animal testing. Fewer Animal Experiments Thanks to Nanosensors - Read more
Novel Compound to Halt Virus Replication
( Source: MEDICA.de )
[04/01/2012] Scientists of Boston University School of Medicine (BUSM) have identified a novel compound that inhibits viruses from replicating. The findings could lead to the development of highly targeted compounds to block the replication of poxviruses, such as the emerging infectious disease Monkey pox. Novel Compound to Halt Virus Replication - Read more
Hepatitis C Virus Hijacks Liver MicroRNA
( Source: MEDICA.de )
[03/01/2012] Scientists at the University of North Carolina, working with colleagues from the University of Colorado, have shown for the first time how a small RNA molecule that regulates gene expression in human liver cells has been hijacked by the hepatitis C virus to ensure its own survival – helping medical scientists understand why a new antiviral drug appears to be effective against the virus. Hepatitis C Virus Hijacks Liver MicroRNA - Read more
Multisensory Integration - When Correlation Implies Causation
( Source: MEDICA.de )
[16/12/2011] New research involving scientists from the Max Planck Institute for Biological Cybernetics, the Bernstein Center for Computational Neuroscience Tübingen (Germany), the University of Oxford, and the University of Bielefeld (Germany) has demonstrated that humans exploit the correlation between the temporal structures of signals to decide which of them to combine and which to keep segregated. Multisensory Integration - When Correlation Implies Causation - Read more
Cholesterol-Lowering Medication Accelerates Depletion of Plaque in Arteries
( Source: MEDICA.de )
[15/12/2011] In a new study, NYU Langone Medical Centre researchers have discovered how cholesterol-lowering drugs called statins promote the breakdown of plaque in the arteries. The findings support a large clinical study that recently showed patients taking high-doses of the cholesterol-lowering medications not only reduced their cholesterol levels but also reduced the amount of plaque in their arteries. Cholesterol-Lowering Medication Accelerates Depletion of Plaque in Arteries - Read more
Protection Against Early Stages of Atherosclerosis
( Source: MEDICA.de )
[14/12/2011] Researchers from Boston University School of Medicine (BUSM) have identified for the first time the A2b adenosine receptor (A2bAR) as a possible new therapeutic target against atherosclerosis resulting from a diet high in fat and cholesterol. The findings may have significant public health implications. Protection Against Early Stages of Atherosclerosis - Read more
Role of Proteins in the Cell Environment
( Source: MEDICA.de )
[14/12/2011] How astrocytes, certain cells of the nervous system, are generated was largely unknown up to now. Researchers of Ruhr-Universität Bochum (Germany) have now investigated what influence the cell environment, known as the extracellular matrix, has on this process. Role of Proteins in the Cell Environment - Read more
Early Success Against Hereditary Bleeding Disorder
( Source: MEDICA.de )
[13/12/2011] Symptoms improved significantly in adults with the bleeding disorder haemophilia B following a single treatment with gene therapy developed by researchers at St. Jude Children's Research Hospital in Memphis and demonstrated to be safe in a clinical trial conducted at the University College London (UCL) in the United Kingdom. Early Success Against Hereditary Bleeding Disorder - Read more
Stopping Dangerous Cell Regrowth Reduces Risk
( Source: MEDICA.de )
[08/12/2011] Like Yin and Yang, the two proteins have opposite effects in the walls of blood vessels. AIF-1 stimulates undesirable formation of new cells after a vascular injury, and IRT-1 has the opposite effect. It is the latter, IRT-1, that researcher of Lund University in Sweden and Temple University in the USA want to use to stop a dangerous development in the artery. Stopping Dangerous Cell Regrowth Reduces Risk - Read more
An Eye on Stem Cells
( Source: MEDICA.de )
[06/12/2011] A single stem cell has the potential to generate offspring that differentiates into a variety of specialised cell types. This has now been shown by a team of biologists at the Heidelberg University (Germany) in the adult retina of the medaka fish as a model system. An Eye on Stem Cells - Read more
New Clues to Development of Autism
( Source: MEDICA.de )
[29/11/2011] Neuroscientists at Stanford University School of Medicine have homed in on potential differences in autistic people's brain cells by studying brain like spheres grown in an elaborate process from skin cells. New Clues to Development of Autism - Read more
Researchers Decode a Puzzling Movement Disorder
( Source: MEDICA.de )
[28/11/2011] Neurodegenerative diseases represent one of the greatest challenges of our aging society. However, investigation into these diseases is made particularly difficult due to the limited availability of human brain tissue. Scientists from the Life and Brain Research Centre and Neurology Clinic of Bonn University (Germany) have now taken a roundabout path. Researchers Decode a Puzzling Movement Disorder - Read more
Better Dealing with Osteoarthritis
( Source: MEDICA.de )
[25/11/2011] A step towards better understanding of the biological mechanism involved in the onset of osteoarthritis (OA), which affects millions of people around the world, has been shown in research carried out at the Hebrew University of Jerusalem and in the United States. Better Dealing with Osteoarthritis - Read more
Improved Method of Electrical Stimulation Could Help Treat
( Source: MEDICA.de )
[24/11/2011] Earlier this fall, a plastic surgery research team at Beth Israel Deaconess Medical Centre (BIDMC) found a new method of nerve stimulation that reduces the device's electrical threshold by 40 per cent, compared with traditional FES therapy. The findings could help researchers develop a safer, more efficient functional electrical stimulation (FES) therapy with fewer side effects. Improved Method of Electrical Stimulation Could Help Treat - Read more
Substance in Cancer Medicine Could Prevent Heart Attacks
( Source: MEDICA.de )
[24/11/2011] A substance in medicines for cancer and epilepsy could also prevent heart attacks, according to researchers at the Sahlgrenska Academy at the University of Gothenburg, Sweden, who have been using it to stimulate the body’s own defence system against blood clots. Substance in Cancer Medicine Could Prevent Heart Attacks - Read more
New Class of Drugs for the Reversible Inhibition of Proteasomes
( Source: MEDICA.de )
[23/11/2011] As the “recycling plant” of the cell, the proteasome regulates vitally important functions. Cancer cells, in particular, are very sensitive because they need the proteasome for their uncontrolled growth. Biochemists at the Technische Universitaet Muenchen (TUM) have now identified the lead structure of a new class of drugs that attacks the proteasome in an unusual way. New Class of Drugs for the Reversible Inhibition of Proteasomes - Read more
Probiotic Protects Intestine from Radiation Injury
( Source: MEDICA.de )
[22/11/2011] Scientists at Washington University School of Medicine in St. Louis have shown that taking a probiotic before radiation therapy can protect the intestine from damage — at least in mice. The new study suggests that taking a probiotic also may help cancer patients avoid intestinal injury, a common problem in those receiving radiation therapy for abdominal cancers. Probiotic Protects Intestine from Radiation Injury - Read more
Protection from Severe Malaria Explained
( Source: MEDICA.de )
[22/11/2011] Why do people with a hereditary mutation of the red blood pigment haemoglobin (as is the case with sickle-cell anaemia prevalent in Africa) not contract severe malaria? Scientists in the group headed by Professor Michael Lanzer of the Department of Infectious Diseases at Heidelberg University Hospital (Germany) have now solved this mystery. Protection from Severe Malaria Explained - Read more
“Nerves cannot be compared with telephone wires“
( Source: MEDICA.de )
[22/11/2011] Chronic neuropathic pain has many reasons and is often poorly diagnosed - at the same time, the origin of the pain has not been fully understood. Therefore scientific pain research has been trying to analyse specific neuropathic pain for some time. “Nerves cannot be compared with telephone wires“ - Read more
Brain Plays Role in Regulating Blood Sugar
( Source: MEDICA.de )
[10/11/2011] Researchers at Albert Einstein College of Medicine of Yeshiva University have demonstrated for the first time that the brain is a key player in regulating glucose metabolism in humans. The findings suggest that drugs targeting the brain and central nervous system could be a novel approach to treating diabetes. Brain Plays Role in Regulating Blood Sugar - Read more
“The cell activity can be modulated as desired“
( Source: MEDICA.de )
[08/11/2011] What exactly happens in the brain during an epileptic seizure? And can this knowledge help in finding better therapies for patients in the future? “The cell activity can be modulated as desired“ - Read more
Metabolic Protein Plays Unexpected Role
( Source: MEDICA.de )
[07/11/2011] The embryonic enzyme pyruvate kinase M2 (PKM2) has a well-established role in metabolism and is highly expressed in human cancers. Now, a team led by researchers at the University of Texas MD Anderson Cancer Centre reports that PKM2 has important non-metabolic functions in cancer formation. Metabolic Protein Plays Unexpected Role - Read more
Nano-Technology Makes Medicine Greener
( Source: MEDICA.de )
[07/11/2011] Researchers at the University of Copenhagen are behind the development of a new method that will make it possible to develop drugs faster and greener. This will lead to cheaper medicine for consumers. Nano-Technology Makes Medicine Greener - Read more
"Among experts we focus far too little on the basics"
( Source: MEDICA.de )
[02/11/2011] If a wound does not heal within four to twelve weeks after emergence, doctors call it a chronic wound. In many cases underlying diseases such as venous or vascular disease or diabetes mellitus are the cause. A successful therapy, however, still presents a challenge and requires an interdisciplinary cooperation. "Among experts we focus far too little on the basics" - Read more
“Junk DNA” May Give Rise to Evolutionary Innovation
( Source: MEDICA.de )
[02/11/2011] The vast majority of the human genome consists of DNA without any apparent function, so-called “junk DNA”. A study of Heidelberg University's Centre for Organismal Studies now highlights this “dark matter” of the genome as a resource for evolutionary novelty. “Junk DNA” May Give Rise to Evolutionary Innovation - Read more
New Top-Down Strategy of Identifying Proteins
( Source: MEDICA.de )
[31/10/2011] The human genome has been mapped. Now, it's on to proteins, a much more daunting task. There are 20,300 genes, but there are millions of distinct protein molecules in our bodies. Many of these hold keys to understanding disease and targeting treatment. A team led by Northwestern University has developed a new "top-down" method that can separate and identify thousands of protein molecules quickly. New Top-Down Strategy of Identifying Proteins - Read more
New Pathway Critical to Heart Arrhythmia
( Source: MEDICA.de )
[28/10/2011] University of Maryland School of Medicine researchers have uncovered a previously unknown molecular pathway that is critical to understanding cardiac arrhythmia and other heart muscle problems. Understanding the basic science of heart and muscle function could open the door to new treatments. New Pathway Critical to Heart Arrhythmia - Read more
Enzyme Controlling Cell Death
( Source: MEDICA.de )
[26/10/2011] Brain damage due to birth asphyxia – where the brain is starved of oxygen around the time of delivery – is normally treated by cooling the infant, but this only helps one baby in nine. New research from the Sahlgrenska Academy at the University of Gothenburg, Sweden, could now pave the way for new ways of treating brain damage in newborns. Enzyme Controlling Cell Death - Read more
“You must not underestimate the capability of these viruses“
( Source: MEDICA.de )
[22/10/2011] Tropical diseases used to appear almost exclusively in remote countries – hence the name. The mosquito bite was annoying, but nevertheless harmless in European regions. But the flying pests keep spreading and spreading. And they carry tiny, but dangerous pathogens. Scientists now found out that these viruses are now settling down in Europe. They are called Sindbis, Batai or Usutu. “You must not underestimate the capability of these viruses“ - Read more
Gene Therapy Without a Needle
( Source: MEDICA.de )
[19/10/2011] For the first time, researchers of Ohio State University have found a way to inject a precise dose of a gene therapy agent directly into a single living cell without a needle. The technique uses electricity to “shoot” bits of therapeutic bio molecules through a tiny channel and into a cell in a fraction of a second. Gene Therapy Without a Needle - Read more
Older Beta Cells Act Young Again
( Source: MEDICA.de )
[14/10/2011] Now, long-time by Juvenile Diabetes Research Foundation International (JDRF)-funded researchers at Stanford University have identified a pathway responsible for the age-related decline, and have shown that they can tweak it to get older beta cells to act young again - and start dividing. Older Beta Cells Act Young Again - Read more
Battle Between the Placenta and Uterus Could Help Explain Preeclampsia
( Source: MEDICA.de )
[12/10/2011] A battle that brews in the mother's womb between the father's biological goal to produce the biggest, healthiest baby possible versus the mother's need to live through delivery might help explain preeclampsia, an often deadly disease of pregnancy. In a new study, Yale researchers describe the mechanism that keeps these conflicting goals in balance. Battle Between the Placenta and Uterus Could Help Explain Preeclampsia - Read more
Circadian Clock May Impact Organ Transplant Success
( Source: MEDICA.de )
[05/10/2011] Health care providers assess blood and tissue type as well as organ size and health to enhance transplant success. New research indicates that checklist might also need to include the circadian clock. Circadian Clock May Impact Organ Transplant Success - Read more
Hormonal Role in Glucose and Fat Metabolism
( Source: MEDICA.de )
[04/10/2011] Hormone researchers at the University of Houston (UH) have their sights set on providing long-term treatment options for diabetes, obesity and cardiovascular diseases by better understanding estradiol, the most potent naturally occurring oestrogen. Hormonal Role in Glucose and Fat Metabolism - Read more
How Viruses Find Their Way Into the Cell Nucleus
( Source: MEDICA.de )
[04/10/2011] Adenoviruses cause respiratory diseases and are more dangerous for humans than previously assumed. They manipulate gatekeeper molecules and infiltrate the cell nucleus with the aid of the host cell. A team of researchers have succeeded in demonstrating this mechanism in detail for the first time. How Viruses Find Their Way Into the Cell Nucleus - Read more
Researchers Discover Key to Survival of Brain Cells
( Source: MEDICA.de )
[30/09/2011] Professor Nicolas G. Bazan and his colleagues of Louisiana State University Health Sciences Centre (LSUHSC) New Orleans have discovered how a key chemical neurotransmitter that interacts with two receptors in the brain promotes either normal function or a disease process - determining whether brain cells live or die. Researchers Discover Key to Survival of Brain Cells - Read more
Scientists Expand Bone Marrow-derived Stem Cells in Culture
( Source: MEDICA.de )
[20/09/2011] All stem cells share the capability to replenish themselves by undergoing self-renewal. So far, efforts to grow and expand scarce blood-forming stem cells in culture for therapeutic applications have been met with limited success. Researchers at the Stowers Institute for Medical Research now successfully expanded cultured hematopoietic stem cells to a hundredfold. Scientists Expand Bone Marrow-derived Stem Cells in Culture - Read more
GPS in the Head?
( Source: MEDICA.de )
[16/09/2011] Professor Motoharu Yoshida and colleagues from Boston University investigated how the rhythmic activity of nerve cells supports spatial navigation. The research scientists showed that cells in the entorhinal cortex, which is important for spatial navigation, oscillate with individual frequencies. These frequencies depend on the position of the cells within the entorhinal cortex. GPS in the Head? - Read more
Uterine Stem Cells to Treat Diabetes
( Source: MEDICA.de )
[16/09/2011] Controlling diabetes may someday involve mining stem cells from the lining of the uterus, Yale School of Medicine researchers report in a new study. The team treated diabetes in mice by converting cells from the uterine lining into insulin-producing cells. Uterine Stem Cells to Treat Diabetes - Read more
Separating a Cancer Prevention Drug from Heart Disease Risk
( Source: MEDICA.de )
[15/09/2011] Several clinical studies have shown that taking the anti-inflammatory drug celecoxib can reduce the risk of developing polyps that lead to colon cancers, at the cost of increasing the risk of heart disease. Researchers at Winship Cancer Institute of Emory University have identified a way that celecoxib pushes cancer cells into suicide, separately from its known effects. Separating a Cancer Prevention Drug from Heart Disease Risk - Read more
New 'Bouncer' Molecule Halts Rheumatoid Arthritis
( Source: MEDICA.de )
[12/09/2011] Researchers at Northwestern University Feinberg School of Medicine have discovered why the immune cells of people with rheumatoid arthritis become hyperactive and attack the joints and bones. The immune cells have lost their bouncer, the burly protein that keeps them in line the same way a bouncer in a nightclub controls rowdy patrons. New 'Bouncer' Molecule Halts Rheumatoid Arthritis - Read more
Researchers Investigate the Attachment of the Bacteria in Detail
( Source: MEDICA.de )
[08/09/2011] Scientists from the Helmholtz Centre for Infection Research (Helmholtz-Zentrum für Infektionsforschung, HZI) in Braunschweig, Germany, have now in cooperation with German and American colleagues uncovered new details of how canonical "entero-hemorrhagic Escherichia coli" bacteria (EHEC), serotype O157:H7, attach to intestinal cells. They deciphered at the atomic level how this binding works. Researchers Investigate the Attachment of the Bacteria in Detail - Read more
Researchers Found Mechanism That Can Help Design Future Therapies
( Source: MEDICA.de )
[06/09/2011] An international team of researchers has found a group of mutations involved in T-cell acute lymphoblastic leukaemia (T-ALL), and showed that certain drugs, already in clinical use to treat other diseases, can eliminate the cells carrying these mutations. Researchers Found Mechanism That Can Help Design Future Therapies - Read more
Endogenous Approach to the Prevention of Allergies
( Source: MEDICA.de )
[05/09/2011] Universitätsmedizin Berlin and the Johannes Gutenberg University in Mainz have clarified an endogenous mechanism that can prevent the development of allergies. They were able to show that certain cells of the immune system, so-called killer dendritic cells, are capable of eliminating allergy cells. The results of the study open up new perspectives for strategies to protect against allergies. Endogenous Approach to the Prevention of Allergies - Read more
New Insight into Impulse Control
( Source: MEDICA.de )
[05/09/2011] How the brain controls impulsive behavior may be significantly different than psychologists have thought for the last 40 years. That is the unexpected conclusion of a study by an international team of neuroscientists. New Insight into Impulse Control - Read more
New Way to Target Shape-shifting Proteins
( Source: MEDICA.de )
[01/09/2011] A molecule which can stop the formation of long protein strands, known as amyloid fibrils, that cause joint pain in kidney dialysis patients has been identified by researchers at the University of Leeds. New Way to Target Shape-shifting Proteins - Read more
Differences in First Temperature Response within Living Cells Shown
( Source: MEDICA.de )
[31/08/2011] Using a modern version of open-wide-and-keep-this-under-your-tongue, scientists today reported taking the temperature of individual cells in the human body, and finding for the first time that temperatures inside do not adhere to the familiar 98.6 degree Fahrenheit norm. Differences in First Temperature Response within Living Cells Shown - Read more
In Cell Culture, the Neighbourhood Matters
( Source: MEDICA.de )
[30/08/2011] Ever since scientists first began growing human cells in lab dishes, they have focused on improving the chemical soup that feeds the cells and helps regulate their growth. But surfaces also matter, says Laura Kiessling, a professor of chemistry at the University of Wisconsin-Madison. In Cell Culture, the Neighbourhood Matters - Read more
New Target for Treatment of Type 2 Diabetes and Prediabetes
( Source: MEDICA.de )
[25/08/2011] Researchers at the Joslin Diabetes Center have shown that an enzyme found in the mitochondria of cells is decreased in the skeletal muscle of those with diabetes, a finding that could lead to the development of drugs to boost the activity of this enzyme in an effort to fight the disease. New Target for Treatment of Type 2 Diabetes and Prediabetes - Read more
Children's Hospitals Are Not Equipped
( Source: MEDICA.de )
[24/08/2011] A new study of children's hospitals nationwide has found them underequipped to handle a major surge of patients in the event of a pandemic, and urges health care institutions and government agencies to immediately review emergency preparedness plans as flu season approaches. Children's Hospitals Are Not Equipped - Read more
Treatments for Breast and Colon Cancers
( Source: MEDICA.de )
[24/08/2011] University of Houston (UH) researchers have their sights set on developing possible treatments for breast and colon cancer. In two separate, yet related, studies professor Cecilia Williams and her team at the Center for Nuclear Receptors and Cell Signaling (CNRCS) explored the role of estrogen hormones in potentially treating and preventing these cancers. Treatments for Breast and Colon Cancers - Read more
Newly Discovered Cell Mechanism to Fight C. Diff
( Source: MEDICA.de )
[23/08/2011] Groundbreaking research encompassing Case Western Reserve University School of Medicine and University Hospitals Case Medical Center, has uncovered a natural defense mechanism that is capable of inactivating the toxin that spreads Clostridium difficile (C. diff) an increasingly common bacterial infection in hospitals and long-term care settings. Newly Discovered Cell Mechanism to Fight C. Diff - Read more
New Risk Score Spots Patients at High Risk of Serious Blood Clots
( Source: MEDICA.de )
[18/08/2011] A new risk prediction tool can identify patients at high risk of serious blood clots who might need preventative treatment. The tool is based on simple variables which the patient is likely to know and could be easily integrated into GP computer systems to risk assess patients prior to hospital admission, long haul flights, or starting medications that carry an increased clotting risk. New Risk Score Spots Patients at High Risk of Serious Blood Clots - Read more
Improved Method Holds Promise for Biomedical Research
( Source: MEDICA.de )
[17/08/2011] Antibodies are the backbone of the immune system—capable of targeting proteins associated with infection and disease. They are also vital tools for biomedical research, the development of diagnostic tests and for new therapeutic remedies. Improved Method Holds Promise for Biomedical Research - Read more
Molecular Pathway Leads to Inflammation in Asthma
( Source: MEDICA.de )
[12/08/2011] Researchers at the University of Pittsburgh have identified a molecular pathway that helps explain how an enzyme elevated in asthma patients can lead to increased mucus production and inflammation that is characteristic of the lung condition. Their findings reveal unique interactions between biological molecules that could be targeted to develop new asthma treatments. Molecular Pathway Leads to Inflammation in Asthma - Read more
How Yeast Chromosomes Avoid the Bad Breaks
( Source: MEDICA.de )
[10/08/2011] During meiosis—the cell division that produces sperm and eggs—repetitive elements place the genome at risk for dangerous rearrangements from genome reshuffling. This recombination typically does not occur in repetitive DNA, in part because much of it is assembled into specialised heterochromatin. Other mechanisms that restrain recombination in repetitive DNA have remained elusive, until now. How Yeast Chromosomes Avoid the Bad Breaks - Read more
Natural Food Preservative That Kills Food-Borne Bacteria
( Source: MEDICA.de )
[09/08/2011] University of Minnesota researchers have discovered and received a patent for a naturally occurring lantibiotic — a peptide produced by a harmless bacteria — that could be added to food to kill harmful bacteria like salmonella, E. coli and listeria. Natural Food Preservative That Kills Food-Borne Bacteria - Read more
New Therapeutic Approaches Against Viruses, Bacteria and Cancer
( Source: MEDICA.de )
[09/08/2011] Scientists from Freie Universität Berlin and the NeuroCure Cluster of Excellence in collaboration with colleagues from Australia and the Leibniz Institute for Molecular Pharmacology (FMP) in Berlin have developed small molecules that inhibit the internalisation of important signaling molecules but also of pathogenic organisms such as the immunodeficiency virus (HIV) and bacteria into cells. New Therapeutic Approaches Against Viruses, Bacteria and Cancer - Read more
Own Skin Cells May Treat Multiple Diseases
( Source: MEDICA.de )
[08/08/2011] The possibility of developing stem cells from a patient's own skin and using them to treat conditions as diverse as Parkinson's disease, Alzheimer's disease and cancer has generated tremendous excitement in the stem cell research community in recent years. Such therapies would avoid the controversial need for using stem cells derived from human embryos. Own Skin Cells May Treat Multiple Diseases - Read more
Why Women Suffer More Autoimmune Disease
( Source: MEDICA.de )
[08/08/2011] Researchers at National Jewish Health have discovered a type of cell that may contribute to autoimmune disease. The findings also suggest why diseases such as lupus, multiple sclerosis and rheumatoid arthritis strike women more frequently than men. Why Women Suffer More Autoimmune Disease - Read more
Protecting Blood Vessels from Complications of Diabetes
( Source: MEDICA.de )
[05/08/2011] Hydrogen sulfide is a foul-smelling gas with an odor resembling that of rotten eggs. Sometimes called "swamp gas," this toxic substance is generally associated with decaying vegetation, sewers and noxious industrial emissions. And — as odd as it may seem — it also plays a critical role in protecting blood vessels from the complications of diabetes, according to a new study. Protecting Blood Vessels from Complications of Diabetes - Read more
Mitochondrial Genome Mutates When Reprogrammed
( Source: MEDICA.de )
[04/08/2011] Induced pluripotent stem cells (iPS cells) can be generated individually for every single person. iPS cells can be generated from adult body cells using the technique of “cellular reprogramming”. The method raises no ethical concerns as it does not involve the destruction of embryos. Mitochondrial Genome Mutates When Reprogrammed - Read more
Safety Checks Could Reduce Radiotherapy Errors
( Source: MEDICA.de )
[04/08/2011] A combination of several well-known safety procedures could greatly reduce patient-harming errors in the use of radiation to treat cancer, according to a new study led by Johns Hopkins researchers. Safety Checks Could Reduce Radiotherapy Errors - Read more
New Light on the Mechanisms of Brain Development
( Source: MEDICA.de )
[03/08/2011] Scientists at the Allen Institute for Brain Science have taken an important step in identifying how the brain organizes itself during development. The findings describe – in more detail than ever before – the consequences of the loss of a key molecule involved in establishing proper brain architecture during brain development. New Light on the Mechanisms of Brain Development - Read more
Cell Position in the Intestinal Epithelium
( Source: MEDICA.de )
[02/08/2011] How do cells know where to position themselves and where to accumulate in order to carry out their functions correctly within each organ? Researchers have revealed the molecular mechanisms responsible for organizing the intestinal epithelium into distinct comportments, defined by frontiers or territories. Cell Position in the Intestinal Epithelium - Read more
Introducing Maspin Protein into Tumor Nucleus Can Stop Growth
( Source: MEDICA.de )
[01/08/2011] According to the Canadian Cancer Society, one in four Canadians will die of cancer. Lawson Health Research Institute's Doctor John Lewis, Doctor Ann Chambers, and colleagues have found new hope for survival. Their new study shows that maspin, a cellular protein, can reduce the growth and spread of cancer cells - but only when it is in the nucleus. Introducing Maspin Protein into Tumor Nucleus Can Stop Growth - Read more
Reprogrammed Kidney Cells Could Cure Kidney Disease
( Source: MEDICA.de )
[28/07/2011] Approximately 60 million people across the globe have chronic kidney disease, and many will need dialysis or a transplant. A new research indicates that patients' own kidney cells can be gathered and reprogrammed. Reprogramming patients' kidney cells could mean that in the future, fewer patients with kidney disease would require complicated, expensive procedures that affect their quality of life. Reprogrammed Kidney Cells Could Cure Kidney Disease - Read more
Unexpected Discovery on Hormone Secretion
( Source: MEDICA.de )
[28/07/2011] A team of geneticists at the Institut de recherches cliniques de Montréal (IRCM), directed by Doctor Jacques Drouin, made an unexpected discovery on hormone secretion. Contrary to common belief, the researchers found that pituitary cells are organized in structured networks. Unexpected Discovery on Hormone Secretion - Read more
Fast Prediction of Axon Behaviour
( Source: MEDICA.de )
[26/07/2011] Researchers at Case Western Reserve University have developed a computer modeling method to accurately predict how a peripheral nerve axon responds to electrical stimuli, slashing the complex work from an inhibitory weeks-long process to just a few seconds. Fast Prediction of Axon Behaviour - Read more
Software Helps Customize Protein Production
( Source: MEDICA.de )
[22/07/2011] A software program developed by a Penn State synthetic biologist could provide biotechnology companies with genetic plans to help them turn bacteria into molecular factories, capable of producing everything from biofuels to medicine. Software Helps Customize Protein Production - Read more
‘Cord-stopper’ Protein Complex Makes Easier to Move
( Source: MEDICA.de )
[20/07/2011] In a study scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have discovered how a protein complex called condensin keeps chromosome arms folded and easy-to-transport, potentially acting as a cord-stopper. ‘Cord-stopper’ Protein Complex Makes Easier to Move - Read more
Regulator of Aggressive Breast Cancer
( Source: MEDICA.de )
[04/07/2011] Researchers at Cold Spring Harbor Laboratory (CSHL) have identified an enzyme that appears to be a significant regulator of breast cancer development. Called PTPN23, the enzyme is a member of a family called protein tyrosine phosphatases, or PTPs, that plays a fundamental role in switching cell signaling on and off. Regulator of Aggressive Breast Cancer - Read more
Bladder Cancer Cells More Susceptible
( Source: MEDICA.de )
[01/07/2011] Researchers at the UC Davis Cancer Center have discovered a way of sensitizing muscle-invasive bladder cancer cells so that they succumb to the toxic effects of chemotherapy. The finding adds to mounting evidence that tiny strands of RNA — called microRNA — play key roles in some of the deadliest types of cancer. Bladder Cancer Cells More Susceptible - Read more
New Brain Cell Production in Adults
( Source: MEDICA.de )
[01/07/2011] A team of North Carolina State University researchers has discovered more about how a gene connected to the production of new brain cells in adults does its job. Their findings could pave the way to new therapies for brain injury or disease. New Brain Cell Production in Adults - Read more
Aurora Proteins in Cell Division
( Source: MEDICA.de )
[29/06/2011] When a cell divides, the genetic information in the chromosomes must be passed on error-free to the daughter cells. Researchers at the Friedrich Miescher Laboratory in Tübingen are studying this process using fission yeast as a model organism. Aurora Proteins in Cell Division - Read more
New Molecular Pathway Involved in Wound-Healing
( Source: MEDICA.de )
[29/06/2011] Scientists from The Scripps Research Institute have identified a surprising new molecular pathway in skin cells that is involved in wound-healing and sensory communication. New Molecular Pathway Involved in Wound-Healing - Read more
“You might describe it as gymnastics for cells“
( Source: MEDICA.de )
[22/06/2011] The cells of our body work within a three-dimensional environment. But under laboratory conditions, experiments are often still performed in Petri dishes, which provide a 2D environment. “You might describe it as gymnastics for cells“ - Read more
Skin Cells Converted Into Brain Cells
( Source: MEDICA.de )
[14/06/2011] A research has proven that it is possible to reprogram mature cells from human skin directly into brain cells, without passing through the stem cell stage. The unexpectedly simple technique involves activating three genes in the skin cells; genes which are already known to be active in the formation of brain cells at the foetal stage. Skin Cells Converted Into Brain Cells - Read more
Eating a High-Fat Diet May Rapidly Injure Brain Cells
( Source: MEDICA.de )
[09/06/2011] Obesity among people who eat a high-fat diet may involve injury to neurons, or nerve cells, in a key part of the brain that controls body weight, according to the authors of a new animal study. Eating a High-Fat Diet May Rapidly Injure Brain Cells - Read more
To Pinpoint Body’s Immunity 'Switch'
( Source: MEDICA.de )
[07/06/2011] Using the only microscope of its kind in Australia, medical scientists have been able for the first time to see the inner workings of T-cells, the front-line troops that alert our immune system to go on the defensive against germs and other invaders in our bloodstream. To Pinpoint Body’s Immunity 'Switch' - Read more
Regulating Angiogenesis May Fight Retinal Disease
( Source: MEDICA.de )
[31/05/2011] Scientists identify a new molecular pathway used to suppress blood vessel branching in the developing retina – a finding with potential therapeutic value for fighting diseases of the retina and a variety of cancers. Regulating Angiogenesis May Fight Retinal Disease - Read more
Researchers Discover Key Molecule
( Source: MEDICA.de )
[30/05/2011] Researchers have discovered what enables embryonic stem cells to differentiate into diverse cell types and thus to be pluripotent. This pluripotency depends on a specific molecule – E-cadherin – hitherto primarily known for its role in mediating cell-cell adhesion as a kind of “intracellular glue”. If E-cadherin is absent, the stem cells lose their pluripotency. Researchers Discover Key Molecule - Read more
Dance as a Minuet or a Mosh?
( Source: MEDICA.de )
[23/05/2011] The physical forces that guide how cells migrate—how they manage to get from place to place in a coordinated fashion inside the living body— are poorly understood. Scientists have, for the first time, devised a way to measure these forces during collective cellular migration. Dance as a Minuet or a Mosh? - Read more
A Key to Fight Drug-Resistant Leukemia
( Source: MEDICA.de )
[20/05/2011] An international team led by researchers at the University of California, San Francisco and joined by scientists of the Freiburg excellence cluster BIOSS – Centre for Biological Signalling Studies, has now identified a protein called BCL6 which plays a key role in the development of drug-resistance in leukemia. A Key to Fight Drug-Resistant Leukemia - Read more
Risk Reduced by Genetic Predisposition for Cell Suicide
( Source: MEDICA.de )
[20/05/2011] A human genetic variant associated with an almost 30 percent reduced risk of developing severe malaria has been identified. Scientists reveal that a variant at the FAS locus can prevent an excessive and potentially hazardous immune response in infected children. Risk Reduced by Genetic Predisposition for Cell Suicide - Read more
Carbon Black Nanoparticles Can Cause Cell Death
( Source: MEDICA.de )
[19/05/2011] Researchers have found that inhaled carbon black nanoparticles create a double source of inflammation in the lungs. Carbon Black Nanoparticles Can Cause Cell Death - Read more
Breast Cancer Cells Adapt to Environmental Stress
( Source: MEDICA.de )
[17/05/2011] An international research team has discovered a new aspect of “metabolic transformation”, the process whereby tumour cells adapt and survive under conditions that would kill normal cells. Breast Cancer Cells Adapt to Environmental Stress - Read more
Discovery of Faint “Quark” Workings
( Source: MEDICA.de )
[13/05/2011] Three years of microscopic experiments on heart cells has led to a discovery by a team of University of Maryland researchers and collaborators of the workings of faint calcium signals in the heart cells, a discovery that may translate into new therapies for heart disease. Discovery of Faint “Quark” Workings - Read more
Thinking Outside the Column
( Source: MEDICA.de )
[02/05/2011] For more than 50 years, a dominating assumption in brain research was that nerve cells in the cortex of the brain are organised in the form of microscopically small columns. Subsequently, it became a textbook standard that connections are created predominantly between nerve cells within these columns. Thinking Outside the Column - Read more
“A diagnosis and classification is still difficult“
( Source: MEDICA.de )
[02/05/2011] Multifaceted clinical patterns hide behind skin blistering. The different types of skin rashes can be caused by infections, allergies as well as internal diseases and are often beyond a reliable diagnosis. “A diagnosis and classification is still difficult“ - Read more
Cancer Cells' Survival Kit
( Source: MEDICA.de )
[27/04/2011] Scientists have discovered new details of how cancer cells escape from tumor suppression mechanisms that normally prevent these damaged cells from multiplying. They also demonstrated a potential link between this cell proliferation control mechanism and the cognitive deficits caused by Down syndrome. Cancer Cells' Survival Kit - Read more
GM-CSF Required in Multiple Sclerosis
( Source: MEDICA.de )
[26/04/2011] The neutralization of the cytokine GM-CSF could halt the development of multiple sclerosis. This was demonstrated by the research team at the University of Zurich in an animal model. GM-CSF Required in Multiple Sclerosis - Read more
Call of the Riled
( Source: MEDICA.de )
[05/04/2011] Researchers say a "stress response" mechanism used by normal cells to cope with harsh or demanding conditions is exploited by cancer cells, which transmit the same stress signal to surrounding cells, triggering an inflammatory response in them that can aid tumor growth. Call of the Riled - Read more
Nurturing Newborn Neurons Sharpens Mind
( Source: MEDICA.de )
[04/04/2011] Researchers, for the first time, pinpointed the effects of enhanced adult neurogenesis by creating mice lacking a gene required for programmed cell death of newborn neurons in the adult hippocampus. Nurturing Newborn Neurons Sharpens Mind - Read more
Development of Acute Myeloid Leukaemia
( Source: MEDICA.de )
[28/03/2011] Researchers have described how the most common gene mutation found in acute myeloid leukaemia starts the process of cancer development and how it can cooperate with a well-defined group of other mutations to cause full-blown leukaemia. Development of Acute Myeloid Leukaemia - Read more
Promise for People With Rapidly Progressing MS
( Source: MEDICA.de )
[22/03/2011] A long term study reports about the effectiveness of replacing bone marrow, purposely destroyed by chemotherapy, with autologous (self) stem cell rescue for people with aggressive forms of multiple sclerosis. Promise for People With Rapidly Progressing MS - Read more
Anxiety Pathways in the Brain
( Source: MEDICA.de )
[10/03/2011] Scientists at Stanford University recently used light to activate mouse neurons and precisely identify neural circuits that increase or decrease anxiety-related behaviors. Anxiety Pathways in the Brain - Read more
Gene Could Hold Key to Cancer
( Source: MEDICA.de )
[09/03/2011] ADAM-12 is the name of a gene that researchers believe could be an important element in the fight against cancer, arthritis, and cardiac hypertrophy, or thickening of the heart's walls. Gene Could Hold Key to Cancer - Read more
How Ovarian Cancer Resists Chemotherapy
( Source: MEDICA.de )
[04/03/2011] Researchers in the university's Faculty of Science & Engineering studied a tiny strand of our genetic makeup known as a MicroRNA, involved in the regulation of gene expression. Cancer occurs when gene regulation goes haywire. How Ovarian Cancer Resists Chemotherapy - Read more
Protein May Help the Virus's Resurgence
( Source: MEDICA.de )
[28/02/2011] New research enhances the current knowledge of how human immunodeficiency virus type-1 (HIV-1), which causes AIDS, controls the cell cycle of cells that it infects. The new findings may shed light on how the virus reactivates after entering a dormant state, called latency. Protein May Help the Virus's Resurgence - Read more
Family of Proteins Essential for Cell Function
( Source: MEDICA.de )
[24/02/2011] Researchers have completed the 3D structural sequence adopted by several essential proteins in the exchange of substances between the extra and intracellular milieu. Family of Proteins Essential for Cell Function - Read more
Strategy for Identifying Biomarkers
( Source: MEDICA.de )
[18/02/2011] A team of biologists, clinical oncologists, pathologists and information scientists has established a strategy for identifying biomarkers. If a particular pattern of these biomarkers can be detected in the blood, this indicates a cancerous disease. Strategy for Identifying Biomarkers - Read more
Problems with Mitochondria
( Source: MEDICA.de )
[17/02/2011] For the last several years, neurologists have been probing a connection between Parkinson's disease and problems with mitochondria, the miniature power plants of the cell. Problems with Mitochondria - Read more
Sugar Residues Regulate Growth and Survival of Nerve Cells
( Source: MEDICA.de )
[15/02/2011] Researchers in Bochum have found out that certain sugar residues in the spinal cord regulate the growth and survival of nerve cells which control the movement of muscles. Sugar Residues Regulate Growth and Survival of Nerve Cells - Read more
How The Immune System is Regulated
( Source: MEDICA.de )
[07/02/2011] Asthma, diabetes, rheumatism: Such diseases can arise when the immune system does not work properly. Researchers from the Universities of Würzburg and Mainz have discovered new findings about the regulation of the immune defense. How The Immune System is Regulated - Read more
Cocktail Helps Turn Skin Cells into Stem Cells
( Source: MEDICA.de )
[04/02/2011] Stem cells are ideal tools to understand disease and develop new treatments; however, they can be difficult to obtain in necessary quantities. Cocktail Helps Turn Skin Cells into Stem Cells - Read more
Brain Nerve Cells Can Be Influenced
( Source: MEDICA.de )
[28/01/2011] What sounds like science fiction is actually possible: thanks to magnetic stimulation, the activity of certain brain nerve cells can be deliberately influenced. What happens in the brain in this context has been unclear up to now. Brain Nerve Cells Can Be Influenced - Read more
Experimental Cancer Approach
( Source: MEDICA.de )
[26/01/2011] The strategy takes aim at a key signaling pathway, called Notch, involved in forming new blood vessels that feed tumor growth. When researchers targeted the Notch1 signaling pathway in mice, the animals developed vascular tumors, primarily in the liver, which led to massive hemorrhages that caused their death. Experimental Cancer Approach - Read more
Reactivating Cancer Suppressor Genes
( Source: MEDICA.de )
[19/01/2011] Scientists have brought cancer cells back under normal control — by reactivating their cancer suppressor genes. The discovery could form a powerful new technology platform for the treatment of cancer of the breast and other cancers. Reactivating Cancer Suppressor Genes - Read more
Skin Provides Australia’s First Adult Stem Cells
( Source: MEDICA.de )
[14/01/2011] Scientists have developed Australia’s first adult induced pluripotent stem cell lines using skin biopsies from patients with the rare genetic disease Friedreich Ataxia (FA). Skin Provides Australia’s First Adult Stem Cells - Read more
New Markers for Allergic Disorders
( Source: MEDICA.de )
[12/01/2011] Researchers at the University of Gothenburg, Sweden, have developed new methods for analysing medical databases that can be used to identify diagnostic markers more quickly and to personalise medication for allergic disorders. They could also reduce the need for animal trials in clinical studies. New Markers for Allergic Disorders - Read more
Not Caused by XMRV
( Source: MEDICA.de )
[21/12/2010] A virus previously thought to be associated with chronic fatigue syndrome is not the cause of the disease, a detailed study led by UCL scientists has shown. Not Caused by XMRV - Read more
Stem Cells Turned into Complex, Functioning Intestinal Tissue
( Source: MEDICA.de )
[13/12/2010] For the first time, scientists have created functioning human intestinal tissue in the laboratory from pluripotent stem cells. Stem Cells Turned into Complex, Functioning Intestinal Tissue - Read more
Mechanism Linked to Tumors Becoming More Aggressive
( Source: MEDICA.de )
[09/12/2010] Researchers at the University of Georgia have discovered a central switch that controls whether cells move or remain stationary. The misregulation of this switch may play a role in the increased movement of tumor cells and in the aggressiveness of tumors themselves. Mechanism Linked to Tumors Becoming More Aggressive - Read more
Possibility of Reversing Damage Caused by MS
( Source: MEDICA.de )
[07/12/2010] Damage caused by multiple sclerosis could be reversed by activating stem cells that can repair injury in the central nervous system, a study has shown. Possibility of Reversing Damage Caused by MS - Read more
Scientists Map Changes in Genetic Networks Caused by DNA Damage
( Source: MEDICA.de )
[06/12/2010] Using a new technology called "differential epistasis maps," an international team of scientists, led by researchers at the University of California, San Diego School of Medicine, has documented for the first time how a cellular genetic network completely rewires itself in response to stress by DNA-damaging agents. Scientists Map Changes in Genetic Networks Caused by DNA Damage - Read more
Incitement to suicide
( Source: MEDICA.de )
[01/12/2010] Each of our somatic cells contains a genetic suicide program, which can be activated by patrolling immune cells. Cancer cells avoid this elimination mechanism. Incitement to suicide - Read more
Miracles can happen
( Source: MEDICA.de )
[01/12/2010] Even in patients with terminal cancer, time and again there are miraculous tumor regressions. Such spectacular developments demonstrate what our self-healing powers are capable off in extreme cases. Miracles can happen - Read more
Potential New Strategy for Treating HIV
( Source: MEDICA.de )
[01/12/2010] Scientists at Gladstone Institute of Virology and Immunology have solved a long-standing mystery about HIV infection—namely how HIV promotes the death of CD4 T cells. Potential New Strategy for Treating HIV - Read more
“A targeted switch off of only the disease-enhancing memory cells would be desirable“
( Source: MEDICA.de )
[01/12/2010] As the core of the adaptive immune system, our memory assumes a central function. The human immune system recognizes a myriad of exogenous agents and scans new pathogens after they invade the body. Subsequently, our immunological memory will remember these pathogens, identify them faster and effectively destroy them. “A targeted switch off of only the disease-enhancing memory cells would be desirable“ - Read more
Melanoma Does Not Conform
( Source: MEDICA.de )
[19/11/2010] University of Michigan researchers have determined that most types of melanoma cells can form malignant tumors, providing new evidence that the deadliest form of skin cancer does not conform to the increasingly popular cancer stem cell model. Melanoma Does Not Conform - Read more
'Grow Rett Syndrome' in a Petri dish
( Source: MEDICA.de )
[18/11/2010] A groundbreaking study revealed that a team of investigators had successfully generated nerve cells using skin cells from four individuals with Rett syndrome. 'Grow Rett Syndrome' in a Petri dish - Read more
Jumpstart and Sustain Liver Regeneration
( Source: MEDICA.de )
[16/11/2010] The liver's unique ability among organs to regenerate itself has been little understood. Now scientists have shed light on how the liver restores itself by demonstrating that endothelial cells - the cells that form the lining of blood vessels - play a key role. Jumpstart and Sustain Liver Regeneration - Read more
Therapy for Patients with a Deadly Subset
( Source: MEDICA.de )
[09/11/2010] A monoclonal antibody targeting a well known cell surface protein inhibited prostate cancer growth and metastasis in an aggressive form of the disease that did not respond to hormone therapy, according to a study by researchers with the UCLA Department of Urology and UCLA’s Jonsson Comprehensive Cancer Center. Therapy for Patients with a Deadly Subset - Read more
Body´s Bacteria Affect the Outcome
( Source: MEDICA.de )
[18/10/2010] New findings suggesting that bacteria in the mouth and/or intestine can affect the the outcome pathogenesis of atherosclerosis and lead to new treatment strategies, reveals research from the University of Gothenburg, Sweden. Body´s Bacteria Affect the Outcome - Read more
Cells Switch Their Profile
( Source: MEDICA.de )
[18/10/2010] Scientists at the University of East Anglia have made an important breakthrough in the way anti-cancer drugs are tested. Cells Switch Their Profile - Read more
Sneaking Spies Into a Cell's Nucleus
( Source: MEDICA.de )
[30/09/2010] Duke University bioengineers have not only figured out a way to sneak molecular spies through the walls of individual cells, they can now slip them into the command center – or nucleus – of those cells, where they can report back important information or drop off payloads. Sneaking Spies Into a Cell's Nucleus - Read more
Neuronal field simulates brain activity
( Source: MEDICA.de )
[29/09/2010] RUB Scientists of the Bernstein Group for Computational Neuroscience developed a computational model, which allows a mathematical description of far reaching interactions between cortical neurons. Neuronal field simulates brain activity - Read more
Researchers Unlock Mystery
( Source: MEDICA.de )
[22/09/2010] Researchers at Columbia University Medical Center have identified a defect in the T cell regulatory pathway which normally controls autoreactive T cells that attack the body’s own tissues. A majority of people with Type 1 Diabetes who were tested in the study were found to have the newly-identified cellular/molecular defect. The researchers were able to successfully correct the defect in-vitro. Researchers Unlock Mystery - Read more
Mechanism Discovered to Increase Immune Response
( Source: MEDICA.de )
[10/09/2010] A team of scientists has discovered a sensor in dendritic cells that recognizes HIV, spurring a more potent immune response by the sentinels to the virus. Mechanism Discovered to Increase Immune Response - Read more
New Frontier in Fighting Cancer
( Source: MEDICA.de )
[02/09/2010] A "game-changing" technique using near infrared light enables scientists to look deeper into the guts of cells, potentially opening up a new frontier in the fights against cancer and many other diseases. New Frontier in Fighting Cancer - Read more
Antibiotic May Reduce Stroke Risk And Injury
( Source: MEDICA.de )
[30/08/2010] A daily dose of an old antibiotic may help diabetics avoid a stroke or at least minimise its damage, Medical College of Georgia researchers report. Antibiotic May Reduce Stroke Risk And Injury - Read more
Waiting For The Right Moment
( Source: MEDICA.de )
[26/08/2010] Pathogens make themselves feel at home in the human body, invading cells and living off the plentiful amenities on offer. Waiting For The Right Moment - Read more
Key in Parkinson's Disease
( Source: MEDICA.de )
[17/08/2010] The immune system may have a key role in the development of Parkinson's disease, say US researchers. Key in Parkinson's Disease - Read more
Genes Associated
( Source: MEDICA.de )
[16/08/2010] Researchers at the University of Gothenburg, Sweden, have for the first time identified 12 genes that could be associated with aggressive breast tumours. The discovery could result in more reliable prognoses and better treatment strategies for patients. Genes Associated - Read more
Human Embryonic Stem Cells and Reprogrammed Cells
( Source: MEDICA.de )
[09/08/2010] Human embryonic stem cells and adult cells reprogrammed to an embryonic stem cell-like state—so-called induced pluripotent stem or iPS cells—exhibit very few differences in their gene expression signatures and are nearly indistinguishable in their chromatin state, according to researchers. Human Embryonic Stem Cells and Reprogrammed Cells - Read more
Gene Brings Teeth in Shape
( Source: MEDICA.de )
[06/08/2010] No healthy teeth without this gene: if during tooth formation (odontogenesis) the so-called Jagged2 gene is inactivated, and hence the Notch signalling pathway interrupted, tooth crowns will be malformed and enamel will be lacking. Gene Brings Teeth in Shape - Read more
Potential Key Regulator Detected
( Source: MEDICA.de )
[04/08/2010] Research into inflammatory bowel disease (IBD) led by UCD Conway Institute scientists has identified a key regulator involved in maintaining the functional integrity of the gut lining. Potential Key Regulator Detected - Read more
Supply and Demand
( Source: MEDICA.de )
[04/08/2010] Most organisms need iron to survive, but too much iron is toxic, and can cause fatal organ failure. The same is true inside cells, where iron balance must also be maintained. Scientists have now identified proteins that ensure iron balance. Supply and Demand - Read more
Helps to Observe Protein Movement
( Source: MEDICA.de )
[28/07/2010] Scientists have shown that a variant form of a fluorescent protein (FP) originally isolated from a reef coral has excellent properties as a marker protein for super-resolution microscopy in live cells. Helps to Observe Protein Movement - Read more
Colon Inflammation Singles out Dangerous Immune Cells
( Source: MEDICA.de )
[23/07/2010] Scientists have constructed a mathematical and computational model of inflammatory bowel disease that allows researchers to simulate the cellular and molecular changes underlying chronic inflammation in humans. Colon Inflammation Singles out Dangerous Immune Cells - Read more
Studying Cells in 3-D
( Source: MEDICA.de )
[23/06/2010] Showing movies in 3-D has produced a box-office bonanza in recent months. Could viewing cell behaviour in three dimensions lead to important advances in cancer research? Studying Cells in 3-D - Read more
Novel Enzyme Linked to Cancer Cell Migration
( Source: MEDICA.de )
[01/06/2010] Scientists at the University of California, San Diego have identified a previously unknown kinase that regulates cell proliferation, shape and migration, and may play a major role in the progression or metastasis of cancer cells. Novel Enzyme Linked to Cancer Cell Migration - Read more
Shortened Therapy Leads to Success
( Source: MEDICA.de )
[01/06/2010] You have breast cancer. A sentence, that is life changing and one that more and more women get to hear. Yet there is reason for hope: According to early research results, a new treatment method could prove more effective than the standard therapy – and it could also prevent women from having nasty side effects. Shortened Therapy Leads to Success - Read more
Picturing infertility
( Source: MEDICA.de )
[19/05/2010] Scientists from Ruhr-Universität Bochum have developed a non-invasive technique that within seconds can distinguish healthy fertile and infertile sperm cells by collecting the spectral chemical fingerprint. The method has the potential for a novel fertility technology and a test scheme which does not only rely on morphological characteristics, but also utilizes chemical signatures. Picturing infertility - Read more
Profile Tumor Cells from Small Samples
( Source: MEDICA.de )
[14/05/2010] Researchers have developed a technique for analyzing the genome of single tumor cells. This allows them to study how tumors develop. It has the potential to help doctors identify dangerous tumor cells from small samples. Profile Tumor Cells from Small Samples - Read more
A "Fat Forward" Research Tool
( Source: MEDICA.de )
[12/05/2010] Researchers in tissue engineering have developed a "fat finder", a microscope-based cell scanner, that can help scientists accelerate their research into new fat-melting drugs. A "Fat Forward" Research Tool - Read more
In Search of a Master Controller
( Source: MEDICA.de )
[10/05/2010] New research suggests that a closely connected trio of regulatory proteins are the “master regulators” in hematopoietic stem cells (HSCs), the self-renewing cells the body uses to make new blood cells. In Search of a Master Controller - Read more
Tumour Cells Need Different Treatment
( Source: MEDICA.de )
[15/04/2010] Cancer cells leftover in the brain after surgery have different properties than the cells in the centre of the tumour, researchers found out. They also react differently to radiation therapy and chemotherapeutic substances. Tumour Cells Need Different Treatment - Read more
Probing Gene Activation
( Source: MEDICA.de )
[13/04/2010] Researchers have developed a new method to investigate the discrete steps necessary to turn on individual genes. The finding allows scientists to analyse the unfolding of DNA, a process required for gene activation. Probing Gene Activation - Read more
“Plasma Makes Bacteria Cell Walls Burst“
( Source: MEDICA.de )
[22/03/2010] Never wash without using soap – this is a slogan that surgeons should keep in mind at work. Hygiene of the future may look quite differently though, according to recent physicist’s findings. “Plasma Makes Bacteria Cell Walls Burst“ - Read more
Surprise for Stroke Researchers
( Source: MEDICA.de )
[16/03/2010] Strokes are less damaging if certain immune cells are absent in the blood. This previously unknown mechanism will be presented by researchers from the University of Würzburg. Surprise for Stroke Researchers - Read more
Insight into Failing Heart Cells
( Source: MEDICA.de )
[26/02/2010] Researchers have been able to see how heart failure affects the surface of an individual heart muscle cell in minute detail, using a new nanoscale scanning technique. Insight into Failing Heart Cells - Read more
Enzyme Critical for Function
( Source: MEDICA.de )
[25/02/2010] Scientists are reporting data to show that the enzyme calcineurin is critical in controlling normal development and function of heart cells, and that loss of the protein leads to heart problems and death in genetically modified mice. Enzyme Critical for Function - Read more
How Nerve Cells Grow
( Source: MEDICA.de )
[24/02/2010] Brain researcher Hiroshi Kawabe has discovered the workings of a process that allows nerve cells in the brain to grow and form complex networks. How Nerve Cells Grow - Read more
New Screening System for Hepatitis C
( Source: MEDICA.de )
[12/02/2010] A newly designed system of identifying molecules for treating hepatitis C might enable scientists to discover novel and effective therapies for the disease of the liver, according to a researcher. New Screening System for Hepatitis C - Read more
Tracing Mutations that Lead to Drug Resistance
( Source: MEDICA.de )
[09/02/2010] Chemists and statisticians have developed a new way to trace mutations in HIV that lead to drug resistance. Tracing Mutations that Lead to Drug Resistance - Read more
Promising for Combating Cancer
( Source: MEDICA.de )
[04/02/2010] Scientists have further developed a potential new treatment against cancer that uses magnetic nanoparticles to attach to cancer cells, removing them from the body. Promising for Combating Cancer - Read more
New 'Suicide' Molecule Halts Arthritis
( Source: MEDICA.de )
[29/01/2010] A researcher has invented a novel way to halt and even reverse rheumatoid arthritis in mice. He developed an imitation of a suicide molecule that floats undetected into overactive immune cells responsible for the disease. New 'Suicide' Molecule Halts Arthritis - Read more
Cells Can Suppress Immune Reaction
( Source: MEDICA.de )
[24/10/2008] In the future, bone marrow transfer to patients with leukaemia could be more secure. Mice experiments have shown that certain cells of the immune system can suppress the dangerous side effects resulting from treatment. Cells Can Suppress Immune Reaction - Read more
Detecting Bacteria With Fish Cells
( Source: MEDICA.de )
[26/09/2008] Microbiologists have developed a possible new way to detect illness-causing bacteria. The approach builds on the colour changes in pigment-bearing cells from Siamese fighting fishes. Detecting Bacteria With Fish Cells - Read more
Hepatitis B Virus Triggers Cell ‘Suicide’
( Source: MEDICA.de )
[11/04/2008] Scientists from the University College London (UCL) have identified a key difference between people who can fight the Hepatitis B virus (HBV) off successfully and those who fail to do so. Hepatitis B Virus Triggers Cell ‘Suicide’ - Read more
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