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April 2012: The Lungs
Caution When Using Genetic Sequencing
( Source: MEDICA.de )
[17/05/2013] The use of genome-wide analysis (GWA), that examines the entirety of an individual's DNA for genomic mutations or variants which can cause health problems is a useful technology for diagnosing disease. But it can also pose major ethical problems if used incorrectly. Caution When Using Genetic Sequencing - Read more
Stability for the Genome
( Source: MEDICA.de )
[10/05/2013] In cancer cells, the genome is often in a chaotic, unstable state. Now, a research group from the Würzburg Biocenter, Germany, found out which enzymes can stabilize DNA. Stability for the Genome - Read more
The Many Faces of the Bacterial Defense System
( Source: MEDICA.de )
[02/05/2013] Even bacteria have a kind of immune system they use to defend themselves against unwanted intruders – in their case, viruses. Scientists at the Helmholtz Center for Infection Research (HZI) in Braunschweig, Germany, were now able to show that this defense system is much more diverse than previously thought and that it comes in multiple versions. The Many Faces of the Bacterial Defense System - Read more
Novel Therapy is Safe
( Source: MEDICA.de )
[25/04/2013] An investigational treatment for an inherited form of Lou Gehrig’s disease has passed an early phase clinical trial for safety, researchers at Washington University School of Medicine in St. Louis and Massachusetts General Hospital report. Novel Therapy is Safe - Read more
Cholera Mutations Could Lead to Severe Disease
( Source: MEDICA.de )
[17/04/2013] The cholera strain that transferred to Haiti in 2010 has multiple toxin gene mutations that may account for the severity of disease and is evolving to be more like a 1800s version of cholera, reports a new Northwestern University study. Cholera Mutations Could Lead to Severe Disease - Read more
Personalized Medicine Eliminates Need for Drug
( Source: MEDICA.de )
[01/02/2013] Using genome-wide analysis, investigators at the University of Montreal have potentially eliminated a lifetime drug prescription that two children with a previously unknown type of adrenal insufficiency had been receiving for 14 years. Personalized Medicine Eliminates Need for Drug - Read more
A Scanner for Hereditary Defects
( Source: MEDICA.de )
[25/01/2013] The body’s own proteins continually scour the genetic material for signs of damage. Researchers from the Institute of Veterinary Pharmacology and Toxicology at the University of Zurich see new possibilities in this damage recognition for improving cancer treatment in humans. A Scanner for Hereditary Defects - Read more
Viruses Attack Cancer Stem Cells
( Source: MEDICA.de )
[10/01/2013] Scientists at the Paul-Ehrlich-Institut (PEI) have successfully created oncolytic viruses which effectively target CD133-positive cancer stem cells to infect and kill them. In animal experiments, multiple tumour foci could be completely eradicated. Viruses Attack Cancer Stem Cells - Read more
Costs of Bringing Research Into Care
( Source: MEDICA.de )
[09/01/2013] Genomic research is widely expected to transform medicine, but progress has been slower than expected. Critics argue that the genomics "promise" has been broken – and that money might be better spent elsewhere. Costs of Bringing Research Into Care - Read more
Heart Cells Become 'Biological Pacemakers'
( Source: MEDICA.de )
[17/12/2012] Cedars-Sinai Heart Institute researchers have reprogrammed ordinary heart cells to become exact replicas of highly specialized pacemaker cells by injecting a single gene (Tbx18) – a major step forward in the search for a biological therapy to correct erratic heartbeats. Heart Cells Become 'Biological Pacemakers' - Read more
Gastrointestinal Defense More Diverse Than Originally Thought
( Source: MEDICA.de )
[03/12/2012] The body stores parts of its memory in the immune system to protect itself against diseases. What seems to be well known as a whole contains many open questions in particular, because the immunological memory does not work the same way all over the body. Gastrointestinal Defense More Diverse Than Originally Thought - Read more
Asia Faces Challenges and Opportunities
( Source: MEDICA.de )
[28/11/2012] The Hinxton Group, an international working group on stem cell research and regulation, approaches relationships of tension in the field of stem cell research with a new consensus statement that focuses on Japan and China. Asia Faces Challenges and Opportunities - Read more
Replication Machinery of Viruses Described
( Source: MEDICA.de )
[23/11/2012] Scientists at The Scripps Research Institute (TSRI) have made a major advance in understanding how flu viruses replicate within infected cells. Replication Machinery of Viruses Described - Read more
How Social Isolation Disrupts Myelin Production
( Source: MEDICA.de )
[15/11/2012] Animals that are socially isolated for prolonged periods make less myelin in the region of the brain responsible for complex emotional and cognitive behavior, researchers at the University at Buffalo say. How Social Isolation Disrupts Myelin Production - Read more
Genetic Networks Identified
( Source: MEDICA.de )
[14/11/2012] New computational analysis identifies gene networks affected in schizophrenia and shows that schizophrenia and autism share related genetic networks, each composed of hundreds of genes. Genetic Networks Identified - Read more
"Migraine is a complex disorder"
( Source: MEDICA.de )
[08/11/2012] A global collaboration of scientists with participation by a team of researchers from the Headache and Pain Center Kiel (“Schmerzklinik Kiel”) has decoded four new gene locations whose changes significantly increase the risk of migraines. Recently in the world’s largest migraine study, the genes of more than 5,000 migraine patients were being examined and compared to 7,000 control persons. "Migraine is a complex disorder" - Read more
"Mechanically Active" DNA Material
( Source: MEDICA.de )
[25/10/2012] Artificial muscles and self-propelled goo may be the stuff of Hollywood fiction, but for scientists from University of California Santa Barbara (UCSB), the reality of it is not that far away. By blending their areas of expertise, the pair have created a dynamic gel made of DNA that mechanically responds to stimuli in much the same way that cells do. "Mechanically Active" DNA Material - Read more
Study Identifies Pathology
( Source: MEDICA.de )
[19/10/2012] A study led by researchers at Boston University School of Medicine provides novel insight into the disease’s impact on the brain. The findings pinpoint areas of the brain most affected and opens the door to examine why some people experience milder forms of the disease than others. Study Identifies Pathology - Read more
Epigenetic Difference Explains the Different Risk
( Source: MEDICA.de )
[18/10/2012] The research team led by Manel Esteller of the Bellvitge Biomedical Research Institute (IDIBELL) has identified an epigenetic change in the twin who will develop breast cancer but not in the healthy one. Epigenetic Difference Explains the Different Risk - Read more
New Findings About Mitchondrial Diseases
( Source: MEDICA.de )
[09/10/2012] Researchers from the Max Planck Institute for Biology of Aging discovered, how and when mitochondrial diseases are inherited, using a new model. This is decided when the future mother herself is still an embryo. New Findings About Mitchondrial Diseases - Read more
Heart Health Starts Earlier than You Think
( Source: MEDICA.de )
[25/09/2012] On World Heart Day, 29th September, the World Heart Federation is calling for people – specifically mothers who are gatekeepers to the home – to take action now to protect their own heart health, as well as that of their children and families to safeguard future generations. Heart Health Starts Earlier than You Think - Read more
Puzzle of B-Cell Lymphoma Development Solved
( Source: MEDICA.de )
[24/09/2012] Doctor Dinis Pedro Calado and Doctor Klaus Rajewsky of the Max Delbrück Center (MDC) have identified subgroups of B cells in germinal centers in which the proto-oncogene Myc, a critical regulator of cellular proliferation, is highly activated. Puzzle of B-Cell Lymphoma Development Solved - Read more
Moving Toward Regeneration
( Source: MEDICA.de )
[03/09/2012] Stowers scientists show how pluripotent stem cells mobilize in wounded planarian worms, to better understand stem cell behaviour in regeneration and disease. Moving Toward Regeneration - Read more
Acute Stress Alters Control of Gene Activity
( Source: MEDICA.de )
[15/08/2012] Acute stress alters the methylation of the DNA and thus the activity of certain genes. This is reported by researchers at the Ruhr-Universität Bochum, Germany, together with colleagues from Basel, Trier and London for the first time. Acute Stress Alters Control of Gene Activity - Read more
Mysterious Paralysis of Childhood
( Source: MEDICA.de )
[30/07/2012] Researchers at Duke University Medical Centre have now discovered that mutations in one gene cause the disease in the majority of patients with a diagnosis of Alternating hemiplegia of childhood (AHC), and because of the root problem they discovered, a treatment may become possible. Mysterious Paralysis of Childhood - Read more
Cancer Drugs with Gene Targets
( Source: MEDICA.de )
[17/07/2012] A new study of NIH/National Cancer Institute details how a suite of web-based tools provides the research community with greatly improved capacity to compare data derived from large collections of genomic information against thousands of drugs. Cancer Drugs with Gene Targets - Read more
New Insights into the Parkinson’s Disease
( Source: MEDICA.de )
[17/07/2012] Scientists at the Hertie Institute for Clinical Brain Research and the University Hospital of Tübingen have –as leaders of a large, international joint study – demonstrated the significance of new genetic risk factors for Parkinson’s disease in different population groups. New Insights into the Parkinson’s Disease - Read more
New Gene Transfer
( Source: MEDICA.de )
[09/07/2012] The challenge of treating patients with genetic disorders in which a single mutated gene is simply too large to be replaced using traditional gene therapy techniques may soon be a thing of the past. A Nationwide Children's Hospital study describes a new gene therapy approach capable of delivering full-length versions of large genes and improving skeletal muscle function. New Gene Transfer - Read more
Gene Mutation Lead to Enlarged Brain Size, Cancer, Autism, Epilepsy
( Source: MEDICA.de )
[04/07/2012] A research team led by Seattle Children's Research Institute has discovered new gene mutations associated with markedly enlarged brain size, or megalencephaly. Mutations in three genes, AKT3, PIK3R2 and PIK3CA, were also found to be associated with a constellation of disorders including cancer, hydrocephalus, epilepsy, autism, vascular anomalies and skin growth disorders. Gene Mutation Lead to Enlarged Brain Size, Cancer, Autism, Epilepsy - Read more
Programmable DNA Scissors
( Source: MEDICA.de )
[03/07/2012] Genetic engineers and genomics researchers should welcome the news from the Lawrence Berkeley National Laboratory (Berkeley Lab) where an international team of scientists has discovered a new and possibly more effective means of editing genomes. Programmable DNA Scissors - Read more
Cognitive-behavioural Therapy Effective in Combating Anxiety Disorders
( Source: MEDICA.de )
[02/07/2012] Whether it is a phobia like spiders or a diagnosis such as obsessive compulsive disorder, new research by University of Houston finds patients suffering from anxiety disorders showed the most improvement when treated with cognitive-behavioural therapy (CBT) in conjunction with a "transdiagnostic" approach – a model that allows therapists to apply one set of principles across anxiety disorders. Cognitive-behavioural Therapy Effective in Combating Anxiety Disorders - Read more
Gene Expression Test Identifies Low-risk Nodules
( Source: MEDICA.de )
[27/06/2012] A new test can be used to identify low-risk thyroid nodules, reducing unnecessary surgeries for people with thyroid nodules that have indeterminate results after biopsy – according to researchers of the University of Pennsylvania. Gene Expression Test Identifies Low-risk Nodules - Read more
Pathogens in Biofilm
( Source: MEDICA.de )
[19/06/2012] People with the hereditary disease "cystic fibrosis" usually die as a result of chronic pulmonary infections. Scientists of the University of Basel have discovered that genetic modifications in a pathogen causing pneumonia help it to persist life-long in the lungs of a patient. Pathogens in Biofilm - Read more
How Infection Can Lead to Cancer
( Source: MEDICA.de )
[13/06/2012] One of the biggest risk factors for liver, colon or stomach cancer is chronic inflammation of those organs, often caused by viral or bacterial infections. A new study from Massachusetts Institute of Technology (MIT) offers the most comprehensive look yet at how such infections provoke tissues into becoming cancerous. How Infection Can Lead to Cancer - Read more
Mutations Impair Childhood Growth
( Source: MEDICA.de )
[30/05/2012] Researchers at the Children's Hospital of Philadelphia studying rare genetic disorders have uncovered insights into those diseases in biological structures that regulate chromosomes when cells divide. Mutations Impair Childhood Growth - Read more
"Personality Genes" May Help Account for Longevity
( Source: MEDICA.de )
[25/05/2012] Researchers at Albert Einstein College of Medicine have found that personality traits like being outgoing, optimistic, easygoing, and enjoying laughter as well as staying engaged in activities may also be part of the longevity genes mix. "Personality Genes" May Help Account for Longevity - Read more
Infections: New Discoveries About Severe Malaria
( Source: MEDICA.de )
[23/05/2012] International researchers have uncovered new knowledge related to host-parasite interaction in severe malaria, concerning how malaria parasites are able to bind to cells in the brain and cause cerebral malaria – the most lethal form of the disease.Infections: New Discoveries About Severe Malaria - Read more
Direct-to-consumer Genetics Tests
( Source: MEDICA.de )
[11/05/2012] Patients see potential benefits from direct-to-consumer genetic testing, but are also concerned about how the test results will be used, and generally are unwilling to pay more than 10 or 20 Dollars for them, according to focus groups conducted by researchers at Loyola University Chicago. Direct-to-consumer Genetics Tests - Read more
Brain Regions Associated with Schizophrenia
( Source: MEDICA.de )
[09/05/2012] New research from the Royal College of Surgeons in Ireland (RCSI) has shown physical changes to exist in specific brain areas implicated in schizophrenia following the use of cannabis during adolescence. The research has shown how cannabis use during adolescence can interact with a gene, called the COMT gene, to cause physical changes in the brain. Brain Regions Associated with Schizophrenia - Read more
Glycogen Accumulation in Neurons Causes Brain Damage
( Source: MEDICA.de )
[03/05/2012] Collaborative research by groups headed by scientists Joan J. Guinovart and Marco Milán at the Institute for Research in Biomedicine (IRB Barcelona) has revealed conclusive evidence about the harmful effects of the accumulation of glucose chains (glycogen) in fly and mouse neurons. Glycogen Accumulation in Neurons Causes Brain Damage - Read more
Nano Nod for Lab on a Chip
( Source: MEDICA.de )
[02/05/2012] You would not know it from appearances, but a metal cube the size of a toaster, created at the University of Alberta, is capable of performing the same genetic tests as most fully equipped modern laboratories — and in a fraction of the time. Nano Nod for Lab on a Chip - Read more
Breakthrough for Degenerative Vision Disorder
( Source: MEDICA.de )
[25/04/2012] A research team, led by Doctor John Guy of Bascom Palmer Eye Institute of the University of Miami, has pioneered a novel technological treatment for Leber Hereditary Optic Neuropathy (LHON), an inherited genetic defect that causes rapid, permanent, and bilateral loss of vision in people of all ages, but primarily males ages 20-40. Breakthrough for Degenerative Vision Disorder - Read more
New Type of Mutation Found
( Source: MEDICA.de )
[16/04/2012] Mayo Clinic researchers have discovered a new class of molecular mutation in various forms of breast cancer, a finding that may shed new light on development and growth of different types of breast tumours. Called fusion transcripts, the mutated forms of RNA may also provide a way to identify tumour subtypes and offer new strategies to treat them, investigators say. New Type of Mutation Found - Read more
Sequencing Technology Decodes DNA Folding Pattern
( Source: MEDICA.de )
[12/04/2012] Using a powerful DNA sequencing methodology, researchers at the Ludwig Institute for Cancer Research have now investigated the three-dimensional structure of DNA folds in the nucleus of a chromosome. The findings provide scientists with a greater understanding about the basic principles of DNA folding and its role in gene regulation. Sequencing Technology Decodes DNA Folding Pattern - Read more
Blueprint for New Drugs That Can Inhibit Hepatitis C Virus
( Source: MEDICA.de )
[20/03/2012] The molecule prompts the Hepatitis C’s viral RNA to open up a portion of its hinge-like structure and encapsulate the inhibitor like a perfectly fit glove. Chemists at the University of California, San Diego have produced the first high resolution structure of a molecule that when attached to the genetic material of the hepatitis C virus prevents it from reproducing. Blueprint for New Drugs That Can Inhibit Hepatitis C Virus - Read more
More Children Living with 'Life-limiting' Conditions
( Source: MEDICA.de )
[12/03/2012] The number of children with conditions such as muscular dystrophy, neurodegenerative disorders or severe cerebral palsy who are surviving into adulthood has been underestimated, a new study led from the University of Leeds shows. More Children Living with 'Life-limiting' Conditions - Read more
How to Rescue the Immune System
( Source: MEDICA.de )
[28/02/2012] In a study Loyola researchers report on a promising new technique that potentially could turn immune system killer T cells into more effective weapons against infections and possibly cancer. How to Rescue the Immune System - Read more
Genome Sequencing Finds Unknown Cause of Epilepsy
( Source: MEDICA.de )
[24/02/2012] Only 10 years ago, deciphering the genetic information from one individual in a matter of weeks to find a certain disease-causing genetic mutation would have been written off as science fiction. Now researchers of the University of Arizona applied Next Generation Genome Sequencing to decipher the entire DNA from a patient who had died from sudden unexplained epileptic death. Genome Sequencing Finds Unknown Cause of Epilepsy - Read more
Cellular Aging Increases Risk
( Source: MEDICA.de )
[17/02/2012] Researchers have long speculated that the shortening of telomeres increases the risk of heart attack and early death. Now a large-scale population study in Denmark involving nearly 20,000 people shows that there is in fact a direct link, and has also given physicians a future way to test the actual cellular health of a person. Cellular Aging Increases Risk - Read more
New Software Key for Personalised Medicine
( Source: MEDICA.de )
[14/02/2012] DNA Sequencing technologies provide massive amounts of data that are not easily processed and translated by scientists. That is why Georgia Tech has created a new data analysis algorithm that quickly transforms complex RNA sequence data into usable content for biologists and clinicians. New Software Key for Personalised Medicine - Read more
Treatment of Tuberculosis Can Be Guided by Patients' Genetics
( Source: MEDICA.de )
[09/02/2012] A gene that influences the inflammatory response to infection may also predict the effectiveness of drug treatment for a deadly form of tuberculosis. That shows a study of an international collaboration between researchers at the University of Washington in Seattle, Duke University, Harvard University, the Oxford University Clinical Research Unit in Vietnam and Kings College London. Treatment of Tuberculosis Can Be Guided by Patients' Genetics - Read more
Accelerates CAGE Analysis on a Single Molecule Sequence
( Source: MEDICA.de )
[02/02/2012] Researchers at the RIKEN Omics Science Center have developed a robotic workflow for sample preparation on a single molecule sequencer which reduces sample preparation time to from 42 days to only 8 days. The workflow uses Cap Analysis of Gene Expression (CAGE), a unique method developed at the OSC for determining transcriptional starting sites in the genome and their expression levels. Accelerates CAGE Analysis on a Single Molecule Sequence - Read more
“The risk of patients dying from sepsis increases the longer the diagnosis takes”
( Source: MEDICA.de )
[01/02/2012] On the website of the German Sepsis Society (Deutsche Sepsis-Gesellschaft) you can find the following definition for the disease called sepsis: A modern definition of sepsis was published in 1989 by Bone. He wrote: Sepsis is defined as an invasion of microorganisms and / or their toxins into the blood stream along with the reaction of the organism to the invasion. “The risk of patients dying from sepsis increases the longer the diagnosis takes” - Read more
Processes Leading to Acute Myeloid Leukaemia
( Source: MEDICA.de )
[31/01/2012] Researchers at UC Santa Barbara have discovered a molecular pathway that may explain how a particularly deadly form of cancer develops. The discovery may lead to new cancer therapies that reprogram cells instead of killing them. Processes Leading to Acute Myeloid Leukaemia - Read more
Rare Disease and Mechanism of Hypertension
( Source: MEDICA.de )
[24/01/2012] Analysing all the genes of dozens of people suffering from a rare form of hypertension, Yale University researchers have discovered a new mechanism that regulates the blood pressure of all humans. Rare Disease and Mechanism of Hypertension - Read more
Novel Approach to View Inner Workings of Viruses
( Source: MEDICA.de )
[13/01/2012] Since the discovery of the microscope, scientists have tried to visualise smaller and smaller structures to provide insights into the inner workings of human cells, bacteria and viruses. Now, researchers at the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) have developed a new way to see structures within viruses that were not clearly seen before. Novel Approach to View Inner Workings of Viruses - Read more
New Gene that Regulates Body Weight
( Source: MEDICA.de )
[05/01/2012] Abraham Kovoor of the University of Rhode Island's College of Pharmacy was studying a brain protein, called RGS9 2, that he had previously related to the involuntary, random and repetitive body movements that are side effects of drugs used to treat Parkinson's disease and schizophrenia. New Gene that Regulates Body Weight - Read more
“Our findings are especially interesting for cancer research”
( Source: MEDICA.de )
[02/01/2012] Today, genome analyses can take up to 30 days. A new database technology is meant to help in analyzing and evaluating vast amounts of medical data in real-time. Doctor Matthieu-P. Schapranow from the Hasso Plattner Institute for Software Systems Engineering (HPI) explains how in-memory technology works and how it benefits personalized medicine. “Our findings are especially interesting for cancer research” - Read more
Cholesterol-Lowering Medication Accelerates Depletion of Plaque in Arteries
( Source: MEDICA.de )
[15/12/2011] In a new study, NYU Langone Medical Centre researchers have discovered how cholesterol-lowering drugs called statins promote the breakdown of plaque in the arteries. The findings support a large clinical study that recently showed patients taking high-doses of the cholesterol-lowering medications not only reduced their cholesterol levels but also reduced the amount of plaque in their arteries. Cholesterol-Lowering Medication Accelerates Depletion of Plaque in Arteries - Read more
Measurements Towards Earlier Diagnosis in Alzheimer's Disease
( Source: MEDICA.de )
[15/12/2011] European PredictAD project, lead by Principal Scientist Jyrki Lötjönen from VTT Technical Research Centre of Finland, has developed a decision support tool for objective diagnostics of Alzheimer's disease. Measurements Towards Earlier Diagnosis in Alzheimer's Disease - Read more
Role of Proteins in the Cell Environment
( Source: MEDICA.de )
[14/12/2011] How astrocytes, certain cells of the nervous system, are generated was largely unknown up to now. Researchers of Ruhr-Universität Bochum (Germany) have now investigated what influence the cell environment, known as the extracellular matrix, has on this process. Role of Proteins in the Cell Environment - Read more
Early Success Against Hereditary Bleeding Disorder
( Source: MEDICA.de )
[13/12/2011] Symptoms improved significantly in adults with the bleeding disorder haemophilia B following a single treatment with gene therapy developed by researchers at St. Jude Children's Research Hospital in Memphis and demonstrated to be safe in a clinical trial conducted at the University College London (UCL) in the United Kingdom. Early Success Against Hereditary Bleeding Disorder - Read more
PSA Testing Can Reduce Unnecessary Prostate Biopsies
( Source: MEDICA.de )
[12/12/2011] Prostate cancer screening that combines an adjusted blood test with other factors including the size of the gland, the patient’s overall weight and family history, can help up to one-quarter of men avoid biopsies and the risks associated with them, a Beth Israel Deaconess Medical Centre-led research team says. PSA Testing Can Reduce Unnecessary Prostate Biopsies - Read more
An Eye on Stem Cells
( Source: MEDICA.de )
[06/12/2011] A single stem cell has the potential to generate offspring that differentiates into a variety of specialised cell types. This has now been shown by a team of biologists at the Heidelberg University (Germany) in the adult retina of the medaka fish as a model system. An Eye on Stem Cells - Read more
Better Dealing with Osteoarthritis
( Source: MEDICA.de )
[25/11/2011] A step towards better understanding of the biological mechanism involved in the onset of osteoarthritis (OA), which affects millions of people around the world, has been shown in research carried out at the Hebrew University of Jerusalem and in the United States. Better Dealing with Osteoarthritis - Read more
Girls with Family History of Breast Disease Should Avoid Alcohol
( Source: MEDICA.de )
[21/11/2011] Adding to research linking alcohol to breast cancer risk, a new study from Washington University School of Medicine in St. Louis shows that adolescent girls with a family history of breast disease — either cancer or the benign lesions that can become cancer – have a higher risk of developing benign breast disease as young women than other girls. Girls with Family History of Breast Disease Should Avoid Alcohol - Read more
Polio Still a Threat to Public Health
( Source: MEDICA.de )
[09/11/2011] Health professionals and researchers across the globe believe they are on the verge of eradicating polio, a devastating virus which can lead to paralysis and death. Despite successful eradication in most countries, there are still four countries where the virus is considered endemic — and many more in which the virus still lurks. Polio Still a Threat to Public Health - Read more
Metabolic Protein Plays Unexpected Role
( Source: MEDICA.de )
[07/11/2011] The embryonic enzyme pyruvate kinase M2 (PKM2) has a well-established role in metabolism and is highly expressed in human cancers. Now, a team led by researchers at the University of Texas MD Anderson Cancer Centre reports that PKM2 has important non-metabolic functions in cancer formation. Metabolic Protein Plays Unexpected Role - Read more
Nano-Technology Makes Medicine Greener
( Source: MEDICA.de )
[07/11/2011] Researchers at the University of Copenhagen are behind the development of a new method that will make it possible to develop drugs faster and greener. This will lead to cheaper medicine for consumers. Nano-Technology Makes Medicine Greener - Read more
“Junk DNA” May Give Rise to Evolutionary Innovation
( Source: MEDICA.de )
[02/11/2011] The vast majority of the human genome consists of DNA without any apparent function, so-called “junk DNA”. A study of Heidelberg University's Centre for Organismal Studies now highlights this “dark matter” of the genome as a resource for evolutionary novelty. “Junk DNA” May Give Rise to Evolutionary Innovation - Read more
New Top-Down Strategy of Identifying Proteins
( Source: MEDICA.de )
[31/10/2011] The human genome has been mapped. Now, it's on to proteins, a much more daunting task. There are 20,300 genes, but there are millions of distinct protein molecules in our bodies. Many of these hold keys to understanding disease and targeting treatment. A team led by Northwestern University has developed a new "top-down" method that can separate and identify thousands of protein molecules quickly. New Top-Down Strategy of Identifying Proteins - Read more
Strides Toward Drug Therapy
( Source: MEDICA.de )
[31/10/2011] Scientists at University of California, Santa Barbara have discovered that patients with an inherited kidney disease may be helped by a drug that is currently available for other uses. Strides Toward Drug Therapy - Read more
Skin Colour Matters When it Comes to Health
( Source: MEDICA.de )
[13/10/2011] A new University of British Columbia study finds that Black Canadians with darker skin are more likely to report poorer health than Black Canadians with lighter skin. The study also suggests that a mismatched racial identity can negatively affect health. Skin Colour Matters When it Comes to Health - Read more
How Viruses Find Their Way Into the Cell Nucleus
( Source: MEDICA.de )
[04/10/2011] Adenoviruses cause respiratory diseases and are more dangerous for humans than previously assumed. They manipulate gatekeeper molecules and infiltrate the cell nucleus with the aid of the host cell. A team of researchers have succeeded in demonstrating this mechanism in detail for the first time. How Viruses Find Their Way Into the Cell Nucleus - Read more
Genetic Factors Behind High Blood Pressure
( Source: MEDICA.de )
[23/09/2011] High blood pressure is a well-known risk factor for heart disease. Researchers at the Sahlgrenska Academy at the University of Gothenburg, Sweden, have participated in an international study of 200,000 Europeans which has identified 16 new genetic variations that affect blood pressure. The discovery is an important step towards better diagnostics and treatment. Genetic Factors Behind High Blood Pressure - Read more
“It is an investment in our economic development“
( Source: MEDICA.de )
[22/09/2011] Prevention is the best medicine, according to the proverb. To internalise this wisdom into as many people as possible is the most important goal of the health prevention. With a view to rising illnesses such as diabetes, mental disorders or adiposity, it is becoming more and more important. “It is an investment in our economic development“ - Read more
New Strategy to Fight AIDS and Other Diseases
( Source: MEDICA.de )
[13/09/2011] Mayo Clinic researchers have developed a genome-based immunization strategy to fight feline AIDS and illuminate ways to combat human HIV/AIDS and other diseases. The goal is to create cats with intrinsic immunity to the feline AIDS virus. New Strategy to Fight AIDS and Other Diseases - Read more
Researchers Successfully Complete Genetic Expedition
( Source: MEDICA.de )
[09/09/2011] Scientists at Charité – Universitätsmedizin Berlin and Max-Delbrück-Center for Molecular Medicine (MDC) have succeeded, in collaboration with 23 research teams from 15 different countries, in discovering a total of 29 new genetic variants that are involved in the genesis of multiple sclerosis (MS), an inflammatory disease of the nervous system. Researchers Successfully Complete Genetic Expedition - Read more
How Yeast Chromosomes Avoid the Bad Breaks
( Source: MEDICA.de )
[10/08/2011] During meiosis—the cell division that produces sperm and eggs—repetitive elements place the genome at risk for dangerous rearrangements from genome reshuffling. This recombination typically does not occur in repetitive DNA, in part because much of it is assembled into specialised heterochromatin. Other mechanisms that restrain recombination in repetitive DNA have remained elusive, until now. How Yeast Chromosomes Avoid the Bad Breaks - Read more
Mutations Cause More Than Half the Cases of Schizophrenia
( Source: MEDICA.de )
[10/08/2011] Columbia University Medical Center researchers have shown that new, or "de novo," protein-altering mutations—genetic errors that are present in patients but not in their parents—play a role in more than 50 percent of "sporadic"—for example, not hereditary—cases of schizophrenia. Mutations Cause More Than Half the Cases of Schizophrenia - Read more
Mitochondrial Genome Mutates When Reprogrammed
( Source: MEDICA.de )
[04/08/2011] Induced pluripotent stem cells (iPS cells) can be generated individually for every single person. iPS cells can be generated from adult body cells using the technique of “cellular reprogramming”. The method raises no ethical concerns as it does not involve the destruction of embryos. Mitochondrial Genome Mutates When Reprogrammed - Read more
Molecular Basis for DNA Breakage
( Source: MEDICA.de )
[21/07/2011] Scientists from the Hebrew University have identified the molecular basis for DNA breakage, a hallmark of cancer cells. Molecular Basis for DNA Breakage - Read more
New Link Between Parkinson’s Disease and Cellular Sorting
( Source: MEDICA.de )
[20/07/2011] Scientists at the Helmholtz Zentrum München and the Technische Universität München working in cooperation with the Medical University of Vienna have identified a mutation associated with a inherited form of late-onset Parkinson’s disease. The mutation occurs in a gene that plays a role in intracellular protein sorting. New Link Between Parkinson’s Disease and Cellular Sorting - Read more
‘Cord-stopper’ Protein Complex Makes Easier to Move
( Source: MEDICA.de )
[20/07/2011] In a study scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have discovered how a protein complex called condensin keeps chromosome arms folded and easy-to-transport, potentially acting as a cord-stopper. ‘Cord-stopper’ Protein Complex Makes Easier to Move - Read more
New Genetic Clues for Schizophrenia
( Source: MEDICA.de )
[12/07/2011] De novo mutations – genetic errors that are present in patients but not in their parents – are more frequent in schizophrenic patients than in normal individuals, according to an international group of scientists led by Doctor Guy A. Rouleau of the University of Montreal and CHU Sainte-Justine Hospital. New Genetic Clues for Schizophrenia - Read more
New Light on Auto-Immune Arthritis
( Source: MEDICA.de )
[12/07/2011] Researchers are one step closer to understanding how an individual’s genetic make-up predisposes them to Ankylosing Spondylitis (AS), a common auto-immune arthritis which causes pain and stiffness of the spine, and in serious cases, progressive fusion of the vertebrae and other affected joints. New Light on Auto-Immune Arthritis - Read more
Diet Can Influence Course of Macular Degeneration
( Source: MEDICA.de )
[07/07/2011] Eating a diet high in vitamin D, as well as the nutrients betaine and methionine, might help reduce the risk of macular degeneration, according to new research conducted by Tufts Medical Center scientists. Diet Can Influence Course of Macular Degeneration - Read more
Early Embryos Can Correct Genetic Abnormalities
( Source: MEDICA.de )
[07/07/2011] Professor William G. Kearns told the annual meeting of the European Society of Human Reproduction and Embryology that a three-day-old embryo with an incorrect number of chromosomes was capable of undergoing "a dynamic process of genetic normalisation" so that by day five, when it had developed to the blastocyst stage, it had become euploid, with the correct number of chromosomes. Early Embryos Can Correct Genetic Abnormalities - Read more
“There is a worldwide advance”
( Source: MEDICA.de )
[01/07/2011] Despite continuing technological and pharmacological advances, physicians are still faced with several medical mysteries. Oftentimes however there is no time to intensely devote to the research for innovative possible solutions of modern diseases. “There is a worldwide advance” - Read more
New Marker to Predict Progressive Kidney Failure
( Source: MEDICA.de )
[17/06/2011] A high level of a hormone that regulates phosphate is associated with an increased risk of kidney failure and death among chronic kidney disease (CKD) patients. New Marker to Predict Progressive Kidney Failure - Read more
Disease Risk Depends on Parental Gender
( Source: MEDICA.de )
[06/06/2011] Overexposure to stress hormones in the womb can program the potential for adverse health effects in those children and the next generation, but effects vary depending on whether the mother or father transmits them, a new animal study suggests. Disease Risk Depends on Parental Gender - Read more
Fighting Cancer With Cancer
( Source: MEDICA.de )
[06/06/2011] A mutant gene long thought to accelerate tumor growth in thyroid cancer patients actually inhibits the spread of malignant cells, showing promise for novel cancer therapies, a Mayo Clinic study has found. Fighting Cancer With Cancer - Read more
Researchers Discover Key Molecule
( Source: MEDICA.de )
[30/05/2011] Researchers have discovered what enables embryonic stem cells to differentiate into diverse cell types and thus to be pluripotent. This pluripotency depends on a specific molecule – E-cadherin – hitherto primarily known for its role in mediating cell-cell adhesion as a kind of “intracellular glue”. If E-cadherin is absent, the stem cells lose their pluripotency. Researchers Discover Key Molecule - Read more
Scientists Find Genetic Basis for Key Parasite Function
( Source: MEDICA.de )
[27/05/2011] Snug inside a human red blood cell, the malaria parasite hides from the immune system and fuels its growth by digesting hemoglobin, the cell's main protein. The parasite, however, must obtain additional nutrients from the bloodstream via tiny pores in the cell membrane. Now, investigators have found the genes that malaria parasites use to create these feeding pores. Scientists Find Genetic Basis for Key Parasite Function - Read more
Heredity Behind Subjective Effects of Alcohol
( Source: MEDICA.de )
[24/05/2011] Scientists have long known that people who have a close relative with alcohol problems themselves run an increased risk of starting to abuse alcohol. The reason for this has not been known, but a study from the University of Gothenburg, Sweden, provides part of the answer. The study shows that people who have a close relative who is an alcoholic react more positively to alcohol than other people. Heredity Behind Subjective Effects of Alcohol - Read more
Identification of a New Protein
( Source: MEDICA.de )
[23/05/2011] Researchers have identified a new protein involved in the development of drug resistance in breast cancer which could be a target for new treatments. Identification of a New Protein - Read more
Risk Reduced by Genetic Predisposition for Cell Suicide
( Source: MEDICA.de )
[20/05/2011] A human genetic variant associated with an almost 30 percent reduced risk of developing severe malaria has been identified. Scientists reveal that a variant at the FAS locus can prevent an excessive and potentially hazardous immune response in infected children. Risk Reduced by Genetic Predisposition for Cell Suicide - Read more
Researchers Identify DNA Region
( Source: MEDICA.de )
[18/05/2011] Researchers at Washington University School of Medicine in St. Louis and King’s College London have independently identified DNA on chromosome 3 that appears to be related to depression. Researchers Identify DNA Region - Read more
'Master Switch' Gene Discovered
( Source: MEDICA.de )
[16/05/2011] Researchers have found that a gene linked to type 2 diabetes and cholesterol levels is in fact a 'master regulator' gene, which controls the behavior of other genes found within fat in the body. 'Master Switch' Gene Discovered - Read more
Serendipity Leads To Lifesaving Discovery
( Source: MEDICA.de )
[12/05/2011] About two years ago, Doctor Philippe Gros, McGill University/Department of Biochemistry, described a mouse mutant that was immunodeficient and hypersensitive to the Bacille Calmette-Guérin (BCG) vaccine and to tuberculosis (TB). In this model, Gros's team had found that the immunodeficiency was caused by a mutation in a regulatory protein of the immune system named IRF8. Serendipity Leads To Lifesaving Discovery - Read more
Clocks in the Human Brain
( Source: MEDICA.de )
[28/04/2011] Until now, the genes contributing to this timing, known as clock genes, have only been found to be active in areas outside the brain, such as the skin and blood cells. Recent findings are the first to show that these genes function in multiple areas of the human brain as well, as was shown previously in animals. Clocks in the Human Brain - Read more
Cancer Cells' Survival Kit
( Source: MEDICA.de )
[27/04/2011] Scientists have discovered new details of how cancer cells escape from tumor suppression mechanisms that normally prevent these damaged cells from multiplying. They also demonstrated a potential link between this cell proliferation control mechanism and the cognitive deficits caused by Down syndrome. Cancer Cells' Survival Kit - Read more
What’s Your Gut Type?
( Source: MEDICA.de )
[21/04/2011] In the future, when you walk into a doctor’s surgery or hospital, you could be asked not just about your allergies and blood group, but also about your gut type. What’s Your Gut Type? - Read more
Rapid Spread Between Bacteria
( Source: MEDICA.de )
[13/04/2011] The part of bacterial DNA that often carries antibiotic resistance is a master at moving between different types of bacteria and adapting to widely differing bacterial species, shows a study. Rapid Spread Between Bacteria - Read more
When a reliable diagnosis becomes rare
( Source: MEDICA.de )
[01/04/2011] There are childhood diseases which are not actually defined as this. Rare diseases just don’t belong in the list of classic infectious diseases. Nevertheless, in over 50 percent of cases they still occur in infancy and during childhood. In most cases it is difficult to put the disease symptoms of these types of illnesses in children into a clear medical category. When a reliable diagnosis becomes rare - Read more
Development of Acute Myeloid Leukaemia
( Source: MEDICA.de )
[28/03/2011] Researchers have described how the most common gene mutation found in acute myeloid leukaemia starts the process of cancer development and how it can cooperate with a well-defined group of other mutations to cause full-blown leukaemia. Development of Acute Myeloid Leukaemia - Read more
Origin of Colon Cancer and Detection of Relapse
( Source: MEDICA.de )
[18/03/2011] Scientists report new data in support of link between stem cells and cancer, opening door to new tools for diagnosis and treatment. Origin of Colon Cancer and Detection of Relapse - Read more
Not Always A Nutritional Problem
( Source: MEDICA.de )
[17/03/2011] Researchers and scientists have succeeded in identifying a genetic cause of magnesium deficiency. Not Always A Nutritional Problem - Read more
Reverse Symptoms of Parkinson's Disease
( Source: MEDICA.de )
[17/03/2011] A gene therapy called NLX-P101 dramatically reduces movement impairment in Parkinson's patients, according to results of a Phase 2 study. The approach introduces a gene into the brain to normalize chemical signaling. Reverse Symptoms of Parkinson's Disease - Read more
Anxiety Pathways in the Brain
( Source: MEDICA.de )
[10/03/2011] Scientists at Stanford University recently used light to activate mouse neurons and precisely identify neural circuits that increase or decrease anxiety-related behaviors. Anxiety Pathways in the Brain - Read more
Gene Could Hold Key to Cancer
( Source: MEDICA.de )
[09/03/2011] ADAM-12 is the name of a gene that researchers believe could be an important element in the fight against cancer, arthritis, and cardiac hypertrophy, or thickening of the heart's walls. Gene Could Hold Key to Cancer - Read more
Strategy for Identifying Biomarkers
( Source: MEDICA.de )
[18/02/2011] A team of biologists, clinical oncologists, pathologists and information scientists has established a strategy for identifying biomarkers. If a particular pattern of these biomarkers can be detected in the blood, this indicates a cancerous disease. Strategy for Identifying Biomarkers - Read more
Gonorrhea Acquires a Piece Of Human DNA
( Source: MEDICA.de )
[15/02/2011] If a human cell and a bacterial cell met at a speed-dating event, they would never be expected to exchange phone numbers, much less genetic material. In more scientific terms, a direct transfer of DNA has never been recorded from humans to bacteria. Until now. Gonorrhea Acquires a Piece Of Human DNA - Read more
Partnership of Genes Affects the Brain's Development
( Source: MEDICA.de )
[14/02/2011] The human brain consists of approximately one hundred billion nerve cells. Each of these cells needs to connect to specific other cells during the brain's development in order to form a fully functional organism. Partnership of Genes Affects the Brain's Development - Read more
Gene Protects Lung from Damage
( Source: MEDICA.de )
[09/02/2011] Lung injury is a common cause of death among patients with pneumonia, sepsis or trauma and in those who have had lung transplants. The damage often occurs suddenly and can cause life-threatening breathing problems and rapid lung failure. Gene Protects Lung from Damage - Read more
Mediator of Blood Pressure Regulation in the Liver Identified
( Source: MEDICA.de )
[27/01/2011] Scientist have now discovered a new group of sensory neurons in the mouse liver which mediates the regulation of blood pressure and metabolism. This control center outside of the brain is triggered simply by drinking water and leads to an elevation of blood pressure in sick and elderly people. Mediator of Blood Pressure Regulation in the Liver Identified - Read more
Promise for Melanoma Diagnosis
( Source: MEDICA.de )
[26/01/2011] A new study shows that a test of biomarkers for DNA methylation is technically feasible and could aid in earlier, more precise diagnosis of melanoma. Promise for Melanoma Diagnosis - Read more
Genetic Variety Causing AIDS
( Source: MEDICA.de )
[20/01/2011] Identifying the time of HIV infection, researchers have identified a simple method to establish when a patient contracted the virus causing . The time of infection can be of importance for the treatment of the illness and it contributes to the understanding of the course of the epidemic. Genetic Variety Causing AIDS - Read more
Reactivating Cancer Suppressor Genes
( Source: MEDICA.de )
[19/01/2011] Scientists have brought cancer cells back under normal control — by reactivating their cancer suppressor genes. The discovery could form a powerful new technology platform for the treatment of cancer of the breast and other cancers. Reactivating Cancer Suppressor Genes - Read more
Kidney Gene Implicated in Increased Heart Failure Risk
( Source: MEDICA.de )
[18/01/2011] Scientists have identified the first DNA sequence variant common in the population that is not only associated with an increased risk of heart failure, but appears to play a role in causing it. Kidney Gene Implicated in Increased Heart Failure Risk - Read more
Skin Provides Australia’s First Adult Stem Cells
( Source: MEDICA.de )
[14/01/2011] Scientists have developed Australia’s first adult induced pluripotent stem cell lines using skin biopsies from patients with the rare genetic disease Friedreich Ataxia (FA). Skin Provides Australia’s First Adult Stem Cells - Read more
Scientists Map Changes in Genetic Networks Caused by DNA Damage
( Source: MEDICA.de )
[06/12/2010] Using a new technology called "differential epistasis maps," an international team of scientists, led by researchers at the University of California, San Diego School of Medicine, has documented for the first time how a cellular genetic network completely rewires itself in response to stress by DNA-damaging agents. Scientists Map Changes in Genetic Networks Caused by DNA Damage - Read more
A Molecular Switch for Memory and Addiction
( Source: MEDICA.de )
[29/11/2010] Scientists from Germany, UK and Italy identify a molecular switch that leads to a sustained increase of calcium in nerve cells and plays a crucial role in the formation of memory and addictive behaviours. A Molecular Switch for Memory and Addiction - Read more
Effective Gene Therapy for Wiskott-Aldrich-Syndrome
( Source: MEDICA.de )
[15/11/2010] A Severe Inborn Immunodeficiency Disease: In a first application of gene therapy for the treatment of Wiskott-Aldrich Syndrome, blood forming bone marrow cells have been corrected by gene transfer. Effective Gene Therapy for Wiskott-Aldrich-Syndrome - Read more
The Use of Gene Defect Discovery
( Source: MEDICA.de )
[02/11/2010] Cardiovascular disease patients who have a genetic defect that makes them less responsive to blood thinners may be helped with an increased dosage, according to results of a pilot study led by a cardiologist at The University of Texas Health Science Center at Houston. The Use of Gene Defect Discovery - Read more
Healthy Lifestyle Confirms Lower Risk
( Source: MEDICA.de )
[13/10/2010] Having a family history of breast cancer can lead some people to wonder if their risk is out of their control. A study of more than 85,000 postmenopausal women observed that regular physical activity, maintaining a healthy weight, and drinking less alcohol lowers breast cancer risk for women with, and without a family history of the disease. Healthy Lifestyle Confirms Lower Risk - Read more
On The Trail of The Epigenetic Code
( Source: MEDICA.de )
[12/10/2010] Scientists from the Max Planck Institute for Biophysical Chemistry in Göttingen have succeeded in creating an experimental system for testing the function of such chemical histone modifications and their influence on the organism. On The Trail of The Epigenetic Code - Read more
Researcher Links Maternal Genes to Selfish Behaviour
( Source: MEDICA.de )
[23/09/2010] If you are more inclined to love thyself than thy neighbour, it could be your mother's fault. Those are the findings of Francisco Úbeda, assistant professor of ecology and evolutionary biology at the University of Tennessee, Knoxville. Researcher Links Maternal Genes to Selfish Behaviour - Read more
Childhood Viral Infection May Be a Cause of Obesity
( Source: MEDICA.de )
[20/09/2010] The emerging idea that obesity may have an infectious origin gets new support in a cross-sectional study by University of California, San Diego School of Medicine researchers who found that children exposed to a particular strain of adenovirus were significantly more likely to be obese. Childhood Viral Infection May Be a Cause of Obesity - Read more
Link to Autism in Boys
( Source: MEDICA.de )
[16/09/2010] New research provides further clues as to why Autism Spectrum Disorder (ASD) affects four times more males than females. Link to Autism in Boys - Read more
Gene's Role for a Lifetime of Memories
( Source: MEDICA.de )
[19/08/2010] St. Jude Children's Research Hospital scientists identify a novel feedback mechanism that regulates differentiation of adult neural stem cells Gene's Role for a Lifetime of Memories - Read more
Genes Associated
( Source: MEDICA.de )
[16/08/2010] Researchers at the University of Gothenburg, Sweden, have for the first time identified 12 genes that could be associated with aggressive breast tumours. The discovery could result in more reliable prognoses and better treatment strategies for patients. Genes Associated - Read more
Genetic Differences Make Some People Susceptible to Meningitis
( Source: MEDICA.de )
[10/08/2010] The research is the largest ever genetic study of meningitis and septicaemia caused by meningococcal bacteria. It suggests that people who develop these diseases have innate differences in their natural defences that leave them unable to attack meningococcal bacteria successfully. Genetic Differences Make Some People Susceptible to Meningitis - Read more
Human Embryonic Stem Cells and Reprogrammed Cells
( Source: MEDICA.de )
[09/08/2010] Human embryonic stem cells and adult cells reprogrammed to an embryonic stem cell-like state—so-called induced pluripotent stem or iPS cells—exhibit very few differences in their gene expression signatures and are nearly indistinguishable in their chromatin state, according to researchers. Human Embryonic Stem Cells and Reprogrammed Cells - Read more
Gene Brings Teeth in Shape
( Source: MEDICA.de )
[06/08/2010] No healthy teeth without this gene: if during tooth formation (odontogenesis) the so-called Jagged2 gene is inactivated, and hence the Notch signalling pathway interrupted, tooth crowns will be malformed and enamel will be lacking. Gene Brings Teeth in Shape - Read more
Helps to Observe Protein Movement
( Source: MEDICA.de )
[28/07/2010] Scientists have shown that a variant form of a fluorescent protein (FP) originally isolated from a reef coral has excellent properties as a marker protein for super-resolution microscopy in live cells. Helps to Observe Protein Movement - Read more
Identification of Critical Genes
( Source: MEDICA.de )
[21/07/2010] Down syndrome is a well known cause of mental retardation and other medical problems, including early onset of Alzheimer disease. It has long been known that Down syndrome is associated with an individual having an additional copy of chromosome 21. Identification of Critical Genes - Read more
Identification of Genes
( Source: MEDICA.de )
[25/06/2010] A team led by a Los Angeles researcher developed a novel approach to efficiently identify disease relevant genes in human complex neurological disorders and demonstrated the effectiveness of this method by applying it to Amyotrophic Lateral Sclerosis (ALS), or Lou Gehrig's Disease. Identification of Genes - Read more
Inhibited Genes Stop Tumour
( Source: MEDICA.de )
[16/06/2010] Tumours disappear if you inhibit the genes responsible for their formation. Previously, any suggestions as to why they behave in this way were nothing more than theories. Researchers at the University of Würzburg now present concrete evidence, confirming a long-held assumption in this matter. Inhibited Genes Stop Tumour - Read more
Effective at protecting children
( Source: MEDICA.de )
[07/06/2010] A new study found out that children and adolescents in non-smoking homes and counties with law promoting smoke-free public places live healthier. Effective at protecting children - Read more
Navigation of Stem Cells in Central Nervous System
( Source: MEDICA.de )
[04/06/2010] By discovering how adult neutral stem cells navigate to injure sites in the central nervous system, US researchers have helped solve a puzzle in the creation of stem cell-based treatments. Navigation of Stem Cells in Central Nervous System - Read more
Biologie of the Breast Cancer Gene
( Source: MEDICA.de )
[26/05/2010] Studies have now established that woman who harbour a mutation in a tumor suppressor gene are at greater risk for developing breats and ovarian cancers. Biologie of the Breast Cancer Gene - Read more
Profile Tumor Cells from Small Samples
( Source: MEDICA.de )
[14/05/2010] Researchers have developed a technique for analyzing the genome of single tumor cells. This allows them to study how tumors develop. It has the potential to help doctors identify dangerous tumor cells from small samples. Profile Tumor Cells from Small Samples - Read more
Genetically Engineered Mosquitoes Against Malaria
( Source: MEDICA.de )
[01/05/2010] Mosquitoes transmit infectious diseases to millions of people every year, including malaria. New research reveals that mosquito genetic engineering may turn the transmitter into a natural 'flying vaccinator'. Genetically Engineered Mosquitoes Against Malaria - Read more
“A Genetic Test for Your Graduation Present“
( Source: MEDICA.de )
[01/05/2010] Individual, goal oriented and without any side effects – this is how more and more patients should be treated in the future. Treatments according to the key-lock principle already partially exist today. MEDICA.de talked to Ivar Roots from the Charité Institute for Clinical Pharmacology and Toxicology about cancer, genes and an unusual present. “A Genetic Test for Your Graduation Present“ - Read more
“Man Is A Giant Lego Building Set“
( Source: MEDICA.de )
[01/05/2010] Some build cars, others houses, and yet others - human cells. Researchers of Synthetic Biology piece genes together as they need them. This is how they intend to cure and even prevent diseases. There are progresses. MEDICA.de spoke to Martin Fussenegger, Professor of Biotechnology and Bioengineering at the Swiss Federal Institute of Technology on how to build a cell and what one can do with it.
“Man Is A Giant Lego Building Set“ - Read more
Calculating Prostate Cancer Risk
( Source: MEDICA.de )
[29/04/2010] Researchers found: The more of a man's direct relatives are affected, the higher is his personal risk to develop prostate cancer himself. The personal risk is the higher the younger affected relatives were at the time of diagnosis. Calculating Prostate Cancer Risk - Read more
New Molecular Subtype of Brain Cancer
( Source: MEDICA.de )
[21/04/2010] A study may lead to better insight into the clinical outcome for some patients with a particularly aggressive type of brain cancer. The research may also provide a framework for development of targeted drug treatments. New Molecular Subtype of Brain Cancer - Read more
Probing Gene Activation
( Source: MEDICA.de )
[13/04/2010] Researchers have developed a new method to investigate the discrete steps necessary to turn on individual genes. The finding allows scientists to analyse the unfolding of DNA, a process required for gene activation. Probing Gene Activation - Read more
Personalised Blood Tests for Cancer
( Source: MEDICA.de )
[19/02/2010] Scientists have used data from the whole genome sequencing of cancer patients to develop individualised blood tests they believe can help physicians tailor patients’ treatments. Personalised Blood Tests for Cancer - Read more
New Genetic Signature Linked to Autism Found
( Source: MEDICA.de )
[09/11/2009] Researchers have uncovered a new genetic signature that correlates strongly with autism and which does not involve changes to the DNA sequence itself. Rather, the changes are in the way the genes are turned on and off. The finding may suggest new approaches to diagnosis and treatment of autism. New Genetic Signature Linked to Autism Found - Read more
Potential Pathogenic Mutation Found
( Source: MEDICA.de )
[29/09/2009] An international team of researchers led by scientists at the Mayo Clinic campus in Florida have found what they believe is the first mutated gene linked to restless legs syndrome, a common neurologic disorder. Potential Pathogenic Mutation Found - Read more
Mutation in a Gene Associated with Cancer
( Source: MEDICA.de )
[19/08/2009] An international group of researchers found three mutations responsible for a form of hereditary deafness in a gene that is implicated in cancer. Mutation in a Gene Associated with Cancer - Read more
Mutation Promotes Restless Legs
( Source: MEDICA.de )
[10/08/2009] An international team of researchers have found what they believe is the first mutated gene linked to restless legs syndrome, a common neurologic disorder. Mutation Promotes Restless Legs - Read more
Genetic Marker Has Been Found
( Source: MEDICA.de )
[30/07/2009] A common variation of the gene involved in regulating neurotransmitters in the brain may be linked to problem behaviors in adults with developmental and intellectual disabilities. Genetic Marker Has Been Found - Read more
PGD May Pose Risks
( Source: MEDICA.de )
[29/07/2009] A new long-term analysis of Preimplantation Genetic Diagnosis (PGD) in mice suggests that this procedure may increase risks of weight gain and memory decline in adulthood. PGD May Pose Risks - Read more
Key Gene Discovered
( Source: MEDICA.de )
[14/07/2009] Scientists have just discovered the gene behind Recessive Omodysplasia, a rare skeletal disease characterised by short-limbed dwarfism and craniofacial anomalies. Key Gene Discovered - Read more
Faster, More Cost-Effective Test Developed
( Source: MEDICA.de )
[10/07/2009] Scientists in Japan are reporting development of a faster, less expensive version of the polymerase chain reaction (PCR), a DNA test widely used in disease diagnosis and other applications. Faster, More Cost-Effective Test Developed - Read more
Hearing Loss Caused By Genes
( Source: MEDICA.de )
[28/04/2009] With the help of a new mouse model, researchers found that the respective microRNA seed region influences the production of sensory hair cells in the inner ear, both in the mouse and in humans. Hearing Loss Caused By Genes - Read more
Magnetic Nanoparticles Navigate Genes
( Source: MEDICA.de )
[06/03/2009] Scientists have developed a new measuring method with which the efficiency of gene transfers in cases of cardiovascular diseases can be investigated. Therefore, magnetic nanoparticles navigate the genes through the body. Magnetic Nanoparticles Navigate Genes - Read more
Depression More Influential Than Genes Or Environment
( Source: MEDICA.de )
[05/03/2009] A history of major depression increases the risk of heart disease over and above any genetic risks common to depression and heart disease, according to researchers. Depression More Influential Than Genes Or Environment - Read more
Genes Linked to Dry AMD
( Source: MEDICA.de )
[29/08/2008] Scientists have discovered a genetic mutation that offers protection against a type of age-related macular degeneration (AMD), a disease of the eye. Genes Linked to Dry AMD - Read more
Checking the Genotype through Click and Buy
( Source: MEDICA.de )
[01/08/2008] Genetic tests offer big potential in the fight against illnesses – if they are used sensible. However, a few years ago the first tests appeared on the internet and now everybody can determine his personal risk to fall ill one day with osteoporosis, high blood pressure or Parkinson - so it seems. It rather is an expensive and unreliable glimpse in the future. Checking the Genotype through Click and Buy - Read more
Secret to Long Life May Not be in the Genes
( Source: MEDICA.de )
[05/05/2008] A research on the bone health of one of the oldest persons in the world, who recently died at the age of 114, reveals that there were no genetic modifications which could have contributed to this longevity. Secret to Long Life May Not be in the Genes - Read more
Hepatitis B Virus Triggers Cell ‘Suicide’
( Source: MEDICA.de )
[11/04/2008] Scientists from the University College London (UCL) have identified a key difference between people who can fight the Hepatitis B virus (HBV) off successfully and those who fail to do so. Hepatitis B Virus Triggers Cell ‘Suicide’ - Read more
Back Pain May Be Influenced by Genes
( Source: MEDICA.de )
[09/04/2008] The findings of a Twin Spine Study have led to a paradigm shift in the way disc degeneration is understood. Researchers find proof that back pain problems may be more a matter of genetics than physical strain. Back Pain May Be Influenced by Genes - Read more
Influence of Genes Involved in Inflammation
( Source: MEDICA.de )
[03/03/2008] A University of Southampton research team has identified a new genetic risk factor for age-related macular degeneration (AMD), a major cause of untreatable blindness in elderly people in developed countries. Influence of Genes Involved in Inflammation - Read more
Genes Related to Disabling Form of Arthritis
( Source: MEDICA.de )
[25/10/2007] Researchers have discovered two genes that cause ankylosing spondylitis(AS), an inflammatory and potentially disabling disease. Genes Related to Disabling Form of Arthritis - Read more
Involved Genes Identified
( Source: MEDICA.de )
[11/09/2007] The human genome has been thoroughly screened in the hunt for the genetic causes of rheumatoid arthritis. An international science team has now presented the involved genes. Involved Genes Identified - Read more
Smoking Turns On Some Genes Permanently
( Source: MEDICA.de )
[07/09/2007] Some changes in genes which occur when smoking are irreversible according to new findings. This could explain why former smokers are still more susceptible to lung cancer. Smoking Turns On Some Genes Permanently - Read more
Genes Restored in Human Inner Ear Cells
( Source: MEDICA.de )
[18/06/2007] Researchers have discovered a way to transfer genes, which they hope will restore hearing, into diseased tissue of the human inner ear. Genes Restored in Human Inner Ear Cells - Read more
Genes May Determine Success
( Source: MEDICA.de )
[16/03/2007] The success of long term hip replacement surgery may lie in the genes, suggests new research. Genes May Determine Success - Read more
Key Genes Identified
( Source: MEDICA.de )
[01/03/2007] The most important genes associated with a risk of developing type-2 diabetes have been identified, researchers report in a new study. This should enable scientists to develop a genetic test to show an individual likelihood of developing diabetes mellitus type 2. Key Genes Identified - Read more
Big Hips or Big Belly - It's in your Genes
( Source: MEDICA.de )
[13/04/2006] Obesity and body fat distribution is more in the genes than previously known, a Joslin Diabetes Center-led study shows. Big Hips or Big Belly - It's in your Genes - Read more
Genes Predict Outcome for Breast Cancer Patients
( Source: MEDICA.de )
[03/04/2006] The 2-gene expression profile of HOXB13 and IL17BR in a woman’s breast cancer predicts risk of recurrence in node-negative patients treated with tamoxifen. Genes Predict Outcome for Breast Cancer Patients - Read more
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