BioLynx Technologies launches Fluorescent-Tagged Drug Surrogates of Chloroquine

Fluorescent labelling of high value drugs that retain biological activity are enormously valuable tools for research and diagnostics.

Chloroquine, best known for its antimalarial properties, has also found other important therapeutic uses in anti-inflammatory, anti-cancer, and treatment of HIV infection.

LynxTag-CQ™BLUE and LynxTag-CQ™GREEN. are proprietary blue and green fluorophore-tagged chloroquine for direct visualization and detection of intracellular drug-cell interactions at low micromolar concentrations. Conventional laboratory equipment such as flow cytometry and fluorescence microscopy is sufficient for qualitative and quantitative studies of drug activity in good comparison to the parent compound chloroquine.

Key Advantages
1. Easy to use. Live cell visualization using Fluorescent-Tagged Drugs (FTDs) requires neither specialized nor complex equipment, or reagents other than flow cytometry or fluorescence microscopy setups, which would allow even small-scale laboratories to utilize this technology
2. Enables in vitro visualization of drug localization in live cells. For drug resistance mechanism studies, it is important to be able to track and record the movement of drugs within live cells.
3. Does not alter the effectiveness of the drug. These FTDs have been shown not to interfere with cellular pathways in the host cell, which results in more precise and useful information pertaining to drug-cell interactions.

Visit us at http://www.biolynxtech.com for more information