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Are Patients Losing Sleep?
Measuring blood pressure at night:
both anticipating and inducing
cardiovascular events; © SXC
Rajiv Agarwal of Indiana University analysed the results of 24-hour blood pressure monitoring in 103 patients with kidney disease. This ambulatory blood pressure monitoring test is commonly performed to assess variations in blood pressure from daytime to nighttime. Blood pressure normally "dips" at night—when it does not, the cardiovascular risks of high blood pressure are much greater. As part of a research study, the patients' activity levels were measured using a wristwatch-like device called an actiwatch.
“We were measuring activity, sleep and ambulatory BP for diagnosing masked hypertension and found this interesting observation,” explains Dr. Agarwal. The lack of the normal nighttime 'dip' in blood pressure was related to increased activity levels, because the blood pressure monitor was disturbing the patients' sleep. On nights when patients were using the blood pressure monitor, they spent an average of 90 minutes less time in bed. They also spent less time asleep and slept less efficiently.
"Blood pressure (BP), measured during sleep correlates better with heart attacks and strokes compared to blood pressure measured in the doctor's office," explains Rajiv Agarwal. "However, if blood pressure measurement disturbs sleep, then it may weaken the relationship between 'sleeping BP' and these cardiovascular events."
Patients who awoke at night during blood pressure monitoring were ten times less as likely to have the normal nighttime 'dip.' "Nighttime blood pressure is lower not because of the time of the day, but because people are asleep," said Agarwal. "The ambulatory monitoring technique can disturb sleep, and therefore raise the nighttime blood pressure as an artifact.”
"Thus sleep quality should be taken into account when interpreting blood pressure during sleep," Agarwal added. He noted that the wristwatch actigraph provides a simple and useful way of measuring activity during 24-hour blood pressure monitoring.
MEDICA.de; Source: American Society of Nephrology (ASN)