Secret to Long Life May Not be in the Genes

The researchers, directed by Universitat Autònoma de Barcelona professor Adolfo Díez Pérez, pointed out a healthy lifestyle, a Mediterranean diet, a temperate climate and regular physical activity as the reasons for his excellent health.

The research team studied the bone mass and analysed the genetics of a man with enviable health who at the time of the study was 113 years old. The research was carried out with four other members of his family: a 101-year-old brother, two daughters aged 81 and 77, and a nephew aged 85, all of them born and still living in a small town of the island of Menorca.

With regard to the genetical analyses, researchers were unsuccessful in finding any mutations in the KLOTHO gene, which is generally related to a good level of mineral density and therefore healthy bones. Neither did they find any mutations in the LRP5 gene, which is associated with longevity. None of the members of the family who participated in the study presented any mutations in this gene.

The results of the research do not rule out the possibility that other genetic mutations could positively influence longevity. However, researchers do point out the fact that the excellent health of this family and of the 113-year-old man in particular, is a healthy lifestyle and regular physical activity.; Source: University of Barcelona