Focus Diagnostics

Quest Diagnostics CE Marks Simplexa™ Test for Cytomegalovirus for Sale in Europe

With the new Focus Diagnostics’ Simplexa molecular test on the 3M™
Integrated Cycler, the company now offers one of the most comprehensive
molecular transplant-testing menus in Europe

Madison, N.J., and Cypress, Calif. – November 15, 2011 -- Quest Diagnostics
Incorporated (NYSE: DGX), the world’s leading provider of diagnostic testing,
information and services, today announced that its Focus Diagnostics business
has CE marked its new Simplexa Cytomegalovirus (CMV) molecular test kit on
the 3M™ Integrated Cycler for distribution to approximately 35 countries in Europe. The test is designed to enable hospital labs to perform advanced molecular testing for cytomegalovirus (CMV), a potentially fatal virus infection in patients with compromised immunity, particularly those undergoing organ transplantation.

Focus Diagnostics will showcase the Simplexa CMV and other Simplexa tests at the MEDICA 2011 International Trade Fair with Congress – World Forum for Medicine, to be held November 16-19, 2011, in Dusseldorf, Germany (Booth
3/C16-1, Hall 3).

The Simplexa CMV test employs real-time polymerase chain reaction to
quantitatively detect CMV in whole blood specimens and plasma. With the CE mark of the Simplexa CMV test, Focus Diagnostics has one of the most comprehensive molecular transplant-testing menus in the European marketplace.
In early 2011, Simplexa EBV and Simplexa BK quantitative assays were granted CE-IVD status. Focus Diagnostics also offers molecular primer pairs for the development of laboratory tests, including JC virus, Varicella-Zoster Virus (VZV), adenovirus and human herpesvirus-6 (HHV-6).

“The ability to detect and quantify CMV and other viruses known to affect organ
transplant and other immunocompromised patients is critical to patient care,” said Jay M. Lieberman, M.D., medical director, infectious disease, Quest Diagnostics
and Focus Diagnostics. “With our Simplexa CMV and other test products, physicians in hospitals and other facilities with molecular labs can more quickly get the laboratory results they need to manage their at-risk patients and avoid potentially life-threatening complications.”

As with other members of the herpes virus family, CMV is typically latent after
primary infection. It can reactivate when the immune system is significantly
weakened, such as following organ transplantation, and cause fever, organ rejection and even death.

Europe represents the largest organ transplantation market in the world, with an
estimated 31,379 organ transplant procedures performed in 2010, according to an analysis by Global Industry Analysis, Inc.

About Simplexa
Focus Diagnostics, a wholly-owned business of Quest Diagnostics, develops and
manufactures the Simplexa line of molecular test products operating on the 3M
Integrated Cycler, a compact, portable testing platform, as part of an exclusive global collaboration with 3M™. Simplexa was the first test kit to be FDA cleared for aiding in the detection and differentiation of the 2009 H1N1 influenza virus, in
May 2010. Additional FDA-cleared Simplexa tests aid the detection of influenza A
and B and respiratory syncytial virus. Several other Simplexa-branded tests,
including for Clostridium difficile, Epstein Barr and BK viruses, are CE marked and
distributed in Europe. In 2011, the Simplexa/3M technology won a gold Medical
Design Excellence Award in the in vitro diagnostics category and an Edison Award for new science and medical diagnostic product.

To learn more about or to order Simplexa and other Focus Diagnostics tests,
please contact Focus Diagnostics at 800-445-0185 (U.S.) or +49-6026-9499540
(Europe), or visit SimplexaDx.com or FocusDx.com.

About Quest Diagnostics
Quest Diagnostics is the world's leading provider of diagnostic testing, information and services that patients and doctors need to make better healthcare decisions. The company offers the broadest access to diagnostic testing services through its network of laboratories and patient service centers, and provides interpretive consultation through its extensive medical and scientific staff. Quest Diagnostics is a pioneer in developing innovative diagnostic tests and advanced healthcare information technology solutions that help improve patient care. Additional company information is available at QuestDiagnostics.com. Follow us at Facebook.com/QuestDiagnostics and Twitter.com/QuestDX.

Quest, Quest Diagnostics, the associated logo, Simplexa, Focus Diagnostics, and all associated Quest Diagnostics marks are the registered trademarks of Quest
Diagnostics. All third party marks - (r)' and (tm)' - are the property of their
respective owners. (c) 2000-2011 Quest Diagnostics Incorporated. All rights

Offermanns S, Rosenthal W (2008). Encyclopedia of Molecular Pharmacology (2nd ed.). Springer. pp. 437–438
Analysts, Inc.