The Binding Site GmbH

Proteinase 3 (cANCA) Antigen Now Available from the Binding Site

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The Binding Site Inc. is pleased to announce the addition of a Proteinase 3 (cANCA) antigen to its expansive offering of clinical and research products and services available to the in-vitro diagnostics (IVD) market. Expressly designed for use as an integral component in solid phase ELISA-based immunoassay test procedures, this Proteinase 3 (cANCA) antigen (manufactured by Arotec Diagnostics) is sure to meet the needs of clinical researchers, medical laboratory professionals and manufacturers of in-vitro diagnostic (IVD) immunoassay kits and diagnostic tests for auto-immune conditions.

Autoantibodies to Proteinase 3 are typically found in the sera of patients with active Wegener's granulomatosis, and less often in other types of systemic vasculitis including microscopic polyangiitis, idiopathic crescentic glomerulonephritis, Churg-Strauss syndrome and polyarteritis nodosa. Derived and sourced from human neutrophils and tested to be free of HBs-Ag, HCV, HIV-1 & HIV-2, this Proteinase 3 auto-antigen exhibits a purity level greater than 95%, as assessed by SDS gel electrophoresis. In addition, this Proteinase 3 antigen displays the highest degrees of activity and specificity, while demonstrating exceptional shelf life stability and lot-to-lot consistency. The product is available in a variety of convenient and operator-oriented packaging formats including 1.0 mg, 0.5 mg and 0.2 mg standard fill vials, with bulk packaging configurations also available.

The Binding Site, Inc. serves the in-vitro diagnostic and life science markets with a comprehensive line of innovative products. For additional information, contact The Binding Site, Inc. at 5889 Oberlin Drive – Suite 101, San Diego, CA 92121 USA. Phone: 800-633-4484; FAX: 858-453-9189; Email: info@thebindingsite.com. Please visit our website at www.thebindingsite.com.