Chronic wounds, allergies and recurrent infections of the skin are a continuous burden for patients. Physical plasma is able to bring relief and is an alternative to already established therapies. Prof. Klaus-Dieter Weltmann from the Leibniz Institute for Plasma Science and Technology e.V. in Greifswald talks about the generation and possibilities of physical plasma for medical purposes. Dr. Georg Daeschlein from the University Hospital Greifswald describes the multiple uses of plasma in skin treatment.