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Protein in mosquito spit can keep Dengue virus in check
Mosquito saliva influences transmission of viruses to a bitten mammalian host. For example, it contains factors that dampen the host immune response and so facilitate infection. A study published in PLOS NTDs reports on a saliva protein with the opposite effect.
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Computational method identifies existing drugs with virus-fighting potential
A new, computer-based screening method could reveal the virus-fighting potential of drugs originally developed to treat other conditions, reports a study in PLOS Computational Biology.
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New strategy identified for treating acute myeloid leukemia
A multi-institutional academic and industry research team led by investigators from Massachusetts General Hospital (MGH) and the Harvard Stem Cell Institute has identified a promising new approach to the treatment of acute myeloid leukemia (AML).
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Potentially harmful chemicals widespread in household dust
First-of-a-kind study reveals top 10 consumer product chemicals in dust with known or suspected health impacts.
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Multifaceted genetic impact of training
Endurance training changes the activity of thousands of genes and give rise to a multitude of altered DNA-copies, RNA, researchers from Karolinska Institutet report. The study, which also nuances the concept of muscle memory, is published in the journal PLOS Genetics.
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Unique molecular atlas of pancreas produced
Researchers at Karolinska Institutet have managed to produce the first molecular map of the genes that are active in the various cells of the human pancreas. They have also revealed differences in genetic activity between people with type 2 diabetes and healthy controls.
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New research delimits the possible causes of celiac disease
The amount of gluten could be a more important clue than breast-feeding or the timing of the introduction of gluten for continued research into the causes of celiac disease (gluten intolerance). This is one of the findings from several extensive studies of children with an increased genetic risk of celiac disease conducted by researchers at Lund University in Sweden.
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Podcasts can help global discussion of palliative care
A new study conducted by the Marie Curie Palliative Care Institute Liverpool (MCPCIL) shows the positive impact and reach podcasts can have on palliative care globally.
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Calls for greater transparency in release of clinical trial data
Researchers have called for greater transparency in the public release of clinical trial data after a study revealed significant under-reporting of side effects in medical treatments.
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Precision medicine trial shows benefit to patients
A clinical trial for types of advanced cancer is the first of its kind to show that precision medicine - or tailoring treatment for individual people - can slow down the time it takes for a tumor to grow back, according to research presented at the Molecular Analysis for Personalized Therapy (MAP) conference.
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