THE RELIABLE IDENTIFICATION OF RESISTANCE MECHANISMS: ESBL, AmpC, MBL, KPC, OXA-48, hVISA,GISA, VRE, CARB
A major problem of hospital infections !
ROSCO tests for detection and confirmation of resistance mechanisms. Unique characteristics ensure that kits are ideal for use in the laboratory:
Long shelf life (Dry crystalline form)
Stable products (No false positives due to antibiotic destruction)
Optimal phenotypic method (Detect genotypic false negatives)
High sensitivity and specificity
Inexpensive and reliable method
Rosco is the leader in the field of phenotypic methods for detection of beta-lactamases and is focusing its research activities in the increasing need for detecting mechanisms of resistance according to EUCAST guidelines. The capability to detect ESBLs, AmpC and carbapenemases (KPC and metallo-â-lactamases) in the laboratory is important to improve the clinical management of infections. Disk (tablet) approximation tests detecting synergy (or antagonism) are useful to screen and detect the mentioned beta-lactamases. The combination of non-susceptibility to carbapenems with synergism between Phenylboronic Acid and a carbapenem are indicative of KPC beta-lactamase.