Differences Analysed

Although inflammatory bowel disease (IBD) - comprising mainly Crohn's disease and ulcerative colitis - is thought to affect about 150,000 people in the United Kingdom, the prevalence of severe IBD is not known. Mortality following hospitalisation for IBD is significant but little has been reported on long-term follow-up.

A new research article addresses this question. The research team from United Kingdom determined the hospitalised prevalence of severe IBD and subsequent five-year mortality in Wales, and investigated associations between severe IBD and social deprivation, distance travelled to hospital, and other socio-demographic characteristics.

They found that hospitalisation for severe Crohn’s disease was more common among women than men and it peaked among younger people aged 16 years. Ulcerative colitis was similar among men and women and was more common among older people. There was no link between social deprivation and ulcerative colitis, but Crohn’s disease was more common among more deprived social groups.

The differing demographic profiles between Crohn’s disease and ulcerative colitis, suggest that environmental factors play a more significant role in the etiology of Crohn’s disease. The findings of this large population-based study on the prevalence and mortality of IBD are also important for service planning and provision, according to the researchers.

MEDICA.de; Source: World Journal of Gastroenterology