Broad Use of Medication in Toddlers

Pediatric cough and cold medications are widely marketed in the U.S. but surprisingly little is known about just how often they are used in children. This information is especially important in light of recent revelations that cough and cold medications are responsible for serious adverse events and even deaths among children, the scientists state.

To define the frequency and patterns of use, the researchers analysed data between 1999 and 2006 from the Slone Survey, a national telephone survey of medication use in a representative sample of the U.S. population. The authors considered all oral medicines that are approved by the U.S. Food and Drug Administration (FDA) to treat children's coughs and colds.

The researchers found that in a given week, at least one cough and cold medication was used by 10.1 percent of U.S. children. In terms of active ingredients contained in these medications, exposure was highest to decongestants and antihistamines (6.3 percent each), followed by anti-cough ingredients (4.1 percent) and expectorants (1.5 percent). Exposures to cough and cold medications was highest among two- to five-year olds and children under two years of age.

Among all the products used, 64.2 percent contained more than one active ingredient. The most commonly used product types were single-ingredient antihistamines, antihistamine/decongestant combinations and antihistamine/decongestant/anti-cough combinations. The researchers also found the use of cough and cold medications declined from 12.3 percent in 1999 to 2000 to 8.4 percent in 2005 to 2006.

According to the researchers, the especially common use of cough and cold medications among young children is noteworthy. "Given concerns about potential harmful effects and lack of evidence proving that these medications are effective in young children, the fact that one in ten U.S. children is using one of these medications is striking," said lead author Louis Vernacchio from Boston University School of Medicine.

MEDICA.de; Source: Boston University