Mediplus Ltd

Accurate and Easy-to-Use Technology Improves Diagnosis of Bladder Outlet Obstruction

urodynamics, urology, LUTS, BOO, prostate, non-invasive
A recent study by Newcastle University1 has found that by introducing the CT3000, a penile cuff test, as part of assessment in men with Lower Urinary Tract symptoms (LUTS), diagnosis is significantly improved.

Urodynamicists were given a short training session and asked to use the penile cuff test as part of a clinical assessment in 30 men with LUTS. Measurement and categorisation of bladder outlet obstruction (BOO) were then compared to those taken by expert observers.

Findings suggested that the penile cuff test was easy-to-use and that this technique can be readily implemented by any Urodynamicists assessing men with LUTS.

In a recent six-site trial on implementing the CT3000 in the clinical care pathway the results show that “Diagnostic category repeatability was similar to that of conventional urodynamics (and) this supports widespread routine use of the penile cuff test”.2

The Centre for Evidence-based Purchasing (CEP) report of the CT3000 system 3, asserts that it offers greater accuracy in diagnosis of BOO than diagnosis on flow rate measurement alone. It also concludes that it is easier, quicker, less expensive and preferred over invasive urodynamics by 80% of patients.

Thousands of men every year with lower urinary tract symptoms have
Trans-urethral Resection of the Prostate (TURP), yet 30% of patients do not notice any change in their symptoms due to inaccurate diagnosis. The CT3000 increases the accuracy of initial diagnosis and success prediction following TURP to 87%.4 The NHS National Technology Adoption Centre is working to develop a “How two Why to Guide” on the CT3000 based on these high levels of evidence, as the CT3000 could save the NHS up to £60m per annum and avoid unnecessary surgery on nearly 7,000 men. 5

James Urie, Sales & Marketing Director commented, “We have had great success in marketing the product throughout Europe and North America. This latest evidence should help to stimulate its adoption within the NHS to further improve services, patient choice and unlock tens of millions of pounds cost savings”.

1.McArdle F, Clarkson B, Robson W et al. Interobserver Agreement for Noinvasive Bladder Pressure Flow Recording with Penile Cuff. J Urol 2009, 182: 2397
2.Clarkson B, Robson W, Griffiths C, McArdle F, Drinnan M, Pickard R. Multisite Evaluation of Noninvasive Bladder Pressure Flow Recording Using the Penile Cuff Device: Assessment of Test-Retest Agreement. J Urol 2008 180 2515-2521
3.National Health Service Centre for Evidenece-based Purchasing, review CEP 0710: Medpilus CT3000 Cuff Machine for Diagnosis of Bladder Outlet Obstruction, July 2007 Available at: http://www.pasa.nhs.uk/PASAWeb/NHSprocurement/CEP . Accessed October 28 2009
4.Harding C, Robson W, Drinnan M, Sajeel M, Ramsden P, Griffiths C, Pickard P. Predicting the Outcome of Prostatectomy Using Noninvasive Bladder Pressure and Urine Flow Measurements. European Urology, 2007 186-192
5.The NHS National Technology Adoption Centre. http://www.technologyadoptioncentre.nhs.uk/